Clinical, Cosmetic and Investigational Dentistry最新文献

{"title":"Effect of Alveolar Ridge Inclination on Dynamic Navigation Accuracy of Implant Surgery: A Retrospective Clinical Study.","authors":"Xuechun Jiang, Ran Zhang, Huiyun Jiang, Ni Zeng, Huimin Nie, Wenjuan Zhou, Zhonghao Liu","doi":"10.2147/CCIDE.S636643","DOIUrl":"10.2147/CCIDE.S636643","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the accuracy of dynamic navigation-guided dental implantation system across different alveolar ridge inclinations.</p><p><strong>Materials and methods: </strong>This retrospective study included 34 patients (120 implants) who underwent dynamic navigation-assisted dental implantation between January 2021 and December 2025. Deviations at the entry point of the initial drill and pilot drill were recorded to analyze the influence of alveolar ridge inclination on surgical accuracy. Preoperative and postoperative cone-beam computed tomography (CBCT) scans were automatically superimposed using specialized software to calculate deviations between planned and actual implant positions. Angular, entry point, and apex deviations were measured in both two-dimensional and three-dimensional measurements.</p><p><strong>Results: </strong>The adjusted GEE analysis showed no significant overall difference in initial drill deviation among the three inclination groups (<i>P</i>=0.062), whereas a significant overall difference was observed in implant entry-point deviation (<i>P</i>=0.023). None of the pairwise comparisons remained statistically significant after FDR correction. In the continuous-angle analysis, ridge angle was significantly associated with initial drill deviation after FDR correction.</p><p><strong>Conclusion: </strong>Alveolar ridge inclination was associated with differences in initial drill deviation in dynamic navigation-assisted implant surgery. Patients with high alveolar ridge inclinations exhibit lower accuracy compared with those with low inclinations.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"636643"},"PeriodicalIF":1.8,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13679535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Modalities for Temporomandibular Disorders: A Cross-Sectional Survey of Knowledge, Perceptions, and Practice Patterns Among Dental Professionals in Sana'a, Yemen.","authors":"Ehab M Abdu, Basem H Al-Huthaifi, Khalid Aldhorae, Abdulrahman M Sadhan, Fatema M Al-Murtadha, Reem Y Al-Qanes, Reem N Alyousofi, Samah A Al-Dailami, Shaima'a K Al-Najar, Asalh N Al-Alie","doi":"10.2147/CCIDE.S641339","DOIUrl":"https://doi.org/10.2147/CCIDE.S641339","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMDs) are common musculoskeletal conditions for which physical modalities-including manual therapy, therapeutic jaw exercises, thermotherapy, electrotherapy, posture correction, and patient education-are recommended as first-line management. However, their implementation remains inconsistent, particularly in low- and middle-income and conflict-affected settings. This study evaluated knowledge, attitudes, clinical practices, and perceived barriers related to physical modalities for TMD management among dental practitioners in Sana'a, Yemen, and identified factors associated with adequate knowledge and practice.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted between February and April 2026 among 426 licensed dentists working in universities, private clinics, and public hospitals in Sana'a. A validated, self-administered questionnaire assessed knowledge (10 items), attitudes (6), practices (6), and barriers (5). Content validity (S-CVI=0.89) and reliability (Cronbach's α: 0.78-0.831) were confirmed. Adequacy was defined as ≥70% of the maximum score. Descriptive statistics, chi-square tests, and multivariable logistic regression were performed.</p><p><strong>Results: </strong>The mean knowledge score was 5.65 ± 1.99/10, with only 32.9% achieving adequate knowledge. Although 68.3% reported positive attitudes, only 37.1% demonstrated adequate clinical practice. The main moderate-to-major barriers were limited access to physiotherapy resources/equipment (63.1%) and lack of formal training (59.9%). Attendance at a TMD course/workshop was the strongest predictor of adequate knowledge (AOR=3.11, 95% CI: 1.95-4.96), positive attitude (AOR=2.74, 95% CI: 1.62-4.63), and adequate practice (AOR=3.86, 95% CI: 2.39-6.23). Six or more TMD patients per month and having ten or more years of clinical experience were also significant predictors.</p><p><strong>Conclusion: </strong>Among dental practitioners in Sana'a, knowledge about evidence-based physical modalities for TMD is insufficient, with a notable gap between positive attitudes and actual clinical practice. These findings highlight the need for strengthened undergraduate and continuing education, improved interprofessional collaboration with physiotherapy services, and enhanced access to physical therapy resources in this resource-limited, conflict-affected setting.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"641339"},"PeriodicalIF":1.8,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Different Origin-Derived Exosomes for Future Regenerative Endodontic Therapies: A Systematic Review.","authors":"Dini Asrianti Bagio, Anggraini Margono, Sylva Dinie Alinda, Shalina Ricardo, Indah Julianto","doi":"10.2147/CCIDE.S638894","DOIUrl":"https://doi.org/10.2147/CCIDE.S638894","url":null,"abstract":"<p><strong>Background: </strong>Exosomes are gaining considerable attention as a cell-free approach for regenerative endodontic procedures, because they naturally regulate cell signaling and actively drive tissue healing. However, the regenerative potential of exosomes may vary by cellular origin, highlighting the need to evaluate source-dependent therapeutic applications.</p><p><strong>Objective: </strong>This systematic review aimed to compare the regenerative potential of exosomes derived from different cellular sources and assess their biological effects, molecular mechanisms, and translational relevance for regenerative endodontic therapies.</p><p><strong>Methods: </strong>A systematic review following PRISMA flow chart 2020 guidelines and a percentage summary of risk-of-bias assessment using the Modified SYRCLE Risk of Bias tool identified 216 eligible studies from PubMed, Web of Science, and Scopus, with 30 studies included in the final detailed synthesis.</p><p><strong>Results: </strong>Evidence consistently demonstrated that exosomes promote cell proliferation, migration, odontogenic differentiation, angiogenesis, and immunomodulation through signaling pathways including AKT, ERK, PI3K/AKT, Wnt/β-catenin, and TGF-β/SMAD. Exosomes derived from dental stem cells exhibited superior tissue-specific regenerative and odontogenic potential, making them particularly suitable for dental pulp regeneration. In contrast, exosomes from non-dental sources offered advantages in accessibility, scalability, and enhancement of early proliferative and angiogenic responses. Furthermore, engineered exosomes and advanced delivery platforms, including hydrogels and biomaterial-based scaffolds, improved therapeutic efficacy by enhancing cargo stability, retention, and targeted tissue regeneration.</p><p><strong>Conclusion: </strong>Exosome-based therapies represent a promising strategy for regenerative endodontics, with therapeutic outcomes strongly influenced by exosome source. Endogenous sources, such as DPSC-derived exosomes, appear most suitable for pulp-dentin complex regeneration but are less practical than exogenous sources, such as PRP, WJMSC, and ADSVF exosomes, for scalable clinical applications. To reach the clinic, upcoming studies need to standardize exosome isolation and profiling, pinpoint specific clinical uses for each source, and incorporate modern delivery biomaterials.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"638894"},"PeriodicalIF":1.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Practices and Attitudes of Dental Practitioners in Managing Alveolar Osteitis: A Cross-Sectional Survey in Yemen.","authors":"Basem H Al-Huthaifi, Ehab M Abdu, Khalid Aldhorae, Abdullmalik N Al-Hamati, Mohammed Al-Maqaleh, Mohammed Al-Labani, Abdullah A Al-Radhi, Nezar M Ayash, Ebrahim G Al-Hakimi, Madyan Hussain Al-Hamidi, Sawraj F Sawraj","doi":"10.2147/CCIDE.S637984","DOIUrl":"https://doi.org/10.2147/CCIDE.S637984","url":null,"abstract":"<p><strong>Background: </strong>Alveolar osteitis (AO) is a common and challenging complication after tooth extraction, with significant variability in clinical practices despite existing guidelines. This study evaluated the practices and attitudes of dental practitioners regarding AO prevention and management and identified factors associated with evidence-based preventive practices in Sana'a, Yemen.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among 412 dental practitioners using a validated questionnaire. Data on demographic characteristics, preventive and management practices, and attitudes were collected. The composite prevention practice score (PS), evidence-based management score (EBMS), and non-evidence-based practice score (NEPS) demonstrated good reliability (Cronbach's α = 0.73-0.84). Descriptive statistics, independent t-tests, one-way ANOVA, Pearson's chi-square test, and multivariable logistic regression were performed. Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>The sample was predominantly young (56.8% aged 24-29 years), male (63.1%), and in early career (47.3% with <5 years' experience). The mean composite scores were as follows: PS, 4.09 ± 0.63; EBMS, 4.17 ± 0.67; and NEPS, 2.77 ± 0.89. Notably, 17.2% of dental practitioners \"always\" prescribed routine antibiotic prophylaxis, and 25.5% \"always\" performed additional curettage. Independent predictors of high prevention practices (defined as PS ≥ median 4.13) included 11-15 years of practice (aOR = 1.87, 95% CI: 1.01-3.46), >20 extractions weekly (aOR = 2.44, 95% CI: 1.10-5.41), frequent surgical extractions (aOR = 1.98, 95% CI: 1.10-3.57), continuing education (aOR = 2.19, 95% CI: 1.32-3.63), positive feasibility attitudes (aOR = 1.55, 95% CI: 1.17-2.06), and greater confidence (aOR = 1.41, 95% CI: 1.07-1.87).</p><p><strong>Conclusion: </strong>Dental practitioners in Sana'a, Yemen, demonstrate moderate-to-good adherence to evidence-based AO care, but a minority employ non-evidence-based practices, particularly routine antibiotics and curettage. Continuing education, positive attitudes, and confidence are associated with better practices. Given the cross-sectional design, causal inferences are precluded. These findings support targeted educational interventions, with interventional studies needed to confirm their effectiveness.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"637984"},"PeriodicalIF":1.8,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception, Knowledge and Clinical Use of Silver Diamine Fluoride Among Dental Professionals in Saudi Arabia: A Cross-Sectional Study.","authors":"Maha Eid, Doaa M Banaamah, Lujain Bajsair, Nedaa M Banaamah, Khadijah M Saidi","doi":"10.2147/CCIDE.S623906","DOIUrl":"10.2147/CCIDE.S623906","url":null,"abstract":"<p><strong>Background: </strong>Silver diamine fluoride (SDF) is a non-invasive, cost-effective agent proven effective in arresting and preventing dental caries. Despite growing global evidence supporting its use, significant gaps exist in self-reported knowledge and clinical adoption among dental professionals. Previous studies in Saudi Arabia focused exclusively on general dentists, leaving perception and knowledge among a diverse dental workforce largely unexplored.</p><p><strong>Objective: </strong>This study aimed to assess the perception, knowledge, and clinical use of SDF among a diverse group of dental professionals in Saudi Arabia, including pediatric dentists, restorative dentists, postgraduate and undergraduate students across both governmental and private practice settings.</p><p><strong>Methods: </strong>A cross-sectional study was conducted using an online self-administered questionnaire distributed via social media and Email between December 2020 and March 2021, using convenience sampling. A total of 320 dental professionals participated. Responses were analyzed using chi-square tests with significance set at p≤0.05.</p><p><strong>Results: </strong>While 61.3% of participants reported awareness of SDF for arresting caries in children, only 20% reported awareness of the correct application frequency and only 25.9% reported knowledge of its cost-effectiveness. The majority (76.9%) had never used SDF clinically. Females demonstrated significantly higher awareness than males across most domains. Self-reported knowledge and willingness to use SDF increased significantly with higher educational qualification and greater clinical experience.</p><p><strong>Conclusion: </strong>Significant gaps in self-reported knowledge persist regarding SDF application frequency, cost-effectiveness, and clinical use among dental professionals in Saudi Arabia. The findings suggest a potential role for integrating SDF into undergraduate dental curricula and providing continuing professional development programs for practicing clinicians. Generalizability is limited by the convenience sampling approach.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"623906"},"PeriodicalIF":1.8,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13584942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral and Socioeconomic Determinants of Tooth Loss in Yemeni Adults: A Cross-Sectional Analysis.","authors":"Basem H Al-Huthaifi, Abdullmalik N Al-Hamati, Ehab M Abdu, Mohammed Al-Maqaleh, Aulfat A Albahari, Mosa A Shubayr, Mohammed Jafer, Mohamed Mansy, Mohammed M Al Moaleem","doi":"10.2147/CCIDE.S634383","DOIUrl":"10.2147/CCIDE.S634383","url":null,"abstract":"<p><strong>Purpose: </strong>Tooth loss is a major public health problem in low- and middle-income countries, particularly where traditional habits such as khat chewing coexist with limited dental care. This study aimed to assess the behavioral and socioeconomic factors associated with oral hygiene, gingival health, and tooth loss among adults in Sana'a, Yemen.</p><p><strong>Methods: </strong>A clinic-based cross-sectional study was conducted among 513 adult patients attending four dental centers in Sana'a Governorate, Yemen, between January and April 2026. Data were collected through clinical examination and structured interviews covering sociodemographic characteristics, oral hygiene practices, khat chewing, and cigarette smoking. Multivariable logistic regression was used to identify independent associations with tooth loss. A two-sided p-value <0.05 was considered significant.</p><p><strong>Results: </strong>The mean age was 41.2 years (SD 14.7); 55.2% were female. Daily toothbrushing was reported by only 32.4% of participants, 76.6% never used dental floss. Mean OHI-S was 2.85 (SD 1.22), with 33.1% having poor oral hygiene; the mean Gingival Index was 1.72 (SD 0.69), with 55.0% exhibiting moderate to severe gingivitis. Daily khat chewing was reported by 30.6%, and 13.1% smoked cigarettes daily. After adjustment, khat chewing (adjusted OR 2.34; 95% CI 1.32-4.15; p=0.003) and cigarette smoking (adjusted OR 3.07; 95% CI 1.68-5.61; p<0.001) were independently associated with increased tooth loss, whereas daily toothbrushing (OR 0.54; 95% CI 0.32-0.91; p=0.021) and regular flossing (OR 0.42; 95% CI 0.21-0.84; p=0.013) provided protective benefits.</p><p><strong>Conclusion: </strong>Khat chewing, cigarette smoking, low socioeconomic status, low education, and infrequent toothbrushing are independently associated with tooth loss among adults attending dental centers in Sana'a, Yemen. Public health interventions should target these modifiable factors, particularly in conflict-affected settings where access to dental care is severely restricted.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"634383"},"PeriodicalIF":1.8,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13577167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect Of Arginine And Spray-Dried Chitosan Pretreatment On Microshear Bond Strength To Bleached Enamel.","authors":"Priscila Oliveira Miranda, Leonardo Santos Barros, Núbia Inocencya Pavesi Pini, Milagros Falcon Aguilar, Flávio Henrique Baggio Aguiar, Cecilia Pedroso Turssi, Roberta Tarkany Basting, Flávia Lucisano Botelho do Amaral, Waldemir Francisco Vieira-Junior","doi":"10.2147/CCIDE.S615559","DOIUrl":"10.2147/CCIDE.S615559","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the effect of experimental solutions containing arginine or spray-dried chitosan on the microshear bond strength of bleached bovine enamel.</p><p><strong>Methodology: </strong>Enamel blocks (5×5×3 mm) were allocated into four groups (n=12): I) unbleached control; II) bleaching only; and bleaching followed by treatment with III) 8% arginine or IV) 2.5% spray-dried chitosan solutions for 5 min prior to adhesive procedures. Bleaching consisted of two sessions of 35% hydrogen peroxide (Whiteness HP, FGM) at a 7-day interval. Two restorations were built per block using a universal adhesive (Scothbond Universal Plus, 3M) and a nanofilled resin composite (Filtek Z350 XT, 3M). Specimens were tested for microshear bond strength (MPa), and failure mode analysis (%). Representative samples of predominant failure, as well as the arginine and chitosan powders, were evaluated by scanning electron microscopy (SEM).</p><p><strong>Results: </strong>Data were analyzed using generalized linear models, chi-square and Fisher's exact test. The unbleached group showed higher MPa values than the bleached groups, which did not differ from each other (p = 0.004). Adhesive failure was the predominant fracture pattern with no significant differences among the groups (p = 0.203).</p><p><strong>Conclusion: </strong>Treatments with arginine or spray-dried chitosan did not differ from the control bleaching group and did not reduce adhesive failures. Neither solution effectively mitigated the immediate reduction in bond strength following bleaching.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"615559"},"PeriodicalIF":1.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13571685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Aging on the Torque Accuracy of Two Different Spring-Style Implant Torque Wrenches: An in vitro Study.","authors":"Gholamreza Esfahanizadeh, Azita Mazaheri Tehrani, Arash Zarbakhsh, Emad Khatib, Elham Ghaffari","doi":"10.2147/CCIDE.S627081","DOIUrl":"10.2147/CCIDE.S627081","url":null,"abstract":"<p><strong>Background and aims: </strong>Accurate torque delivery is critical for achieving proper implant preload and preventing screw loosening, yet torque wrenches may lose precision with repeated clinical use. This study aimed to assess how aging influences the torque accuracy of spring-type dental torque wrenches.</p><p><strong>Materials and methods: </strong>Five new spring-type dental torque wrenches from Neodent^® and Intra-Lock^® were tested at their lower and upper torque limits. Torque was measured using a calibrated digital torque meter; each wrench was activated 10 times per setting, and the mean of three consistent readings was recorded. Mechanical aging was simulated through 1000 continuous tightening-loosening cycles at each wrench's maximum torque. Torque measurements were repeated after 500 and 1000 cycles following the same protocol. Data were analyzed using one-way ANOVA (α = 0.05).</p><p><strong>Results: </strong>Both torque wrench brands showed a significant reduction in torque accuracy at the upper limit after 500 and 1000 mechanical aging cycles (p < 0.001). At 1000 cycles, upper-limit torque decreased by 0.67 N·cm (2.2%) for Intra-Lock and 0.55 N·cm (1.7%) for Neodent compared with baseline values. At the lower limit, a significant change was observed for Intra-Lock (p = 0.014), whereas no significant change was observed for Neodent (p = 0.132). Across all measurement stages, Neodent delivered significantly higher upper-limit torque than Intra-Lock (p = 0.020), whereas no significant difference was observed at the lower limit (p = 0.132).</p><p><strong>Conclusion: </strong>Within the limitations of this in vitro study, repeated mechanical aging significantly reduced torque accuracy at the upper torque limit, although the observed reductions were small in absolute terms and remained within commonly used clinical tolerance thresholds. These findings support routine monitoring and calibration of spring-type torque wrenches to maintain reliable torque delivery and implant stability.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"627081"},"PeriodicalIF":1.8,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13559878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148929145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental Radiophobia: A Narrative Review of Prevalence, Associated Factors, and Public Health Consequences of Dental Radiography Fear in the Community - With a Focus on Both Patient and Clinician-Level Fear.","authors":"Fatemeh Pourmohammadi-Nejad, Negar Nourizadeh, Ali Mehdipour, Aliakbar Yousefi-Ahmadipour","doi":"10.2147/CCIDE.S631460","DOIUrl":"10.2147/CCIDE.S631460","url":null,"abstract":"<p><strong>Background: </strong>Dental radiography is an indispensable diagnostic tool, yet many patients experience fear specifically associated with radiographic examinations. This phenomenon-dental radiophobia-represents an exaggerated fear of ionizing radiation in the dental setting. This review examines both patient-level fear and clinician-level radiophobia, which manifests as unfounded concern about low-dose radiation that impedes CBCT adoption.</p><p><strong>Methods: </strong>A narrative review was conducted using PubMed, Scopus, and Web of Science (2000-2025). Search terms included \"dental radiophobia\", \"fear of dental X‑rays\", and \"dental radiography anxiety\" combined with \"prevalence\", \"risk factors\", and \"public health\". Peer‑reviewed English‑language studies on human subjects were included. Data extraction was thematic.</p><p><strong>Results: </strong>General dental fear affects 10-20% of children/adolescents. In adults, meta‑analyses report a pooled prevalence of high dental anxiety of 18% (95% CI 10-30%) and dental phobia of 3%. For dental radiography, mean fear scores are low (0.8 ± 1.8 on a 0-10 visual analogue scale) but with high variance, and pain during intraoral procedures is a significant predictor. Key associated factors include female sex, younger age, lower education, prior painful radiographic experiences, limited radiation knowledge, and reliance on internet information. Clinician radiophobia (unfounded concern about low‑dose radiation) impedes CBCT adoption. Public health consequences include patient refusal of radiographs, avoidance of care, delayed diagnosis, increased oral disease burden, and medico‑legal liability.</p><p><strong>Conclusion: </strong>Dental radiophobia is a clinically relevant phenomenon with measurable prevalence, identifiable risk factors, and tangible public health implications. Effective management includes non‑pharmacological behavioral techniques, improved patient communication, and evidence‑based radiation risk communication. Future research should focus on validated instruments and targeted interventions.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"631460"},"PeriodicalIF":1.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13552401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148911088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Habitual Khat (<i>Catha edulis</i>) Chewing and Oral Reactive Hyperplastic Lesions: A Cross-Sectional Clinicopathological Study in Yemen.","authors":"Ammar M Al-Ashwal, Shaima'a Abdulraqeeb Yahya Rajeh, Rofaida Jubarah, Mohammed M Al Moaleem, Haneen G Al-Affari, Alaa Khaled, Lana Sayal","doi":"10.2147/CCIDE.S640334","DOIUrl":"10.2147/CCIDE.S640334","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinicopathological characteristics of oral reactive hyperplastic lesions (RHLs) and evaluate their association with habitual khat (<i>Catha edulis</i>) chewing in a Yemeni dental population.</p><p><strong>Methods: </strong>This cross-sectional clinicopathological study included 1197 Yemeni patients with 48 histopathologically confirmed RHLs. Demographic characteristics; periodontal status; oral hygiene; and behavioral habits, including khat chewing and smoking, were recorded. Clinical lesion features and histopathological diagnoses were assessed. Associations between khat-chewing status and clinicopathological variables were analyzed by using Pearson's chi-squared or Fisher's exact test, with statistical significance set at P < 0.05.</p><p><strong>Results: </strong>Habitual khat chewing was significantly associated with male gender (P = 0.015), smoking status (P = 0.002), and periodontitis (P = 0.005). Among lesion-related variables, lesion size was significantly associated with khat chewing, with lesions larger than 1 cm occurring more frequently among khat chewers than among nonchewers (P = 0.026). No significant associations were identified between khat chewing and lesion anatomical site (P = 0.604), clinical course (P = 1.000), or histopathological diagnosis (P = 0.762).</p><p><strong>Conclusion: </strong>Habitual khat chewing was associated with increased periodontal destruction and large oral RHLs but showed no association with lesion location, clinical behavior, or histopathological subtype. These findings suggest that khat acts as a chronic local irritant that may amplify reactive tissue proliferation without altering the underlying histopathological pattern of RHLs.</p><p><strong>Clinical relevance: </strong>The assessment of khat-chewing habits should be incorporated into routine oral examinations because chronic exposure may contribute to increased lesion burden and periodontal deterioration.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"18 ","pages":"640334"},"PeriodicalIF":1.8,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13549300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148905296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}