Clinical, Cosmetic and Investigational Dentistry最新文献

{"title":"General Dentist's Knowledge and Attitude Towards Non-Surgical Endodontic Retreatment in Tunisia: A Cross-Sectional Study.","authors":"Kumaravel Kaliaperumal, Emna Hidoussi Sakly, Alessandro Leite Cavalcanti, Abinaya Gayathri, Kumaran Subramanian, Nabil Nasraoui, Mohammad Aly Ibrahim, Salma Aly Ibrahim","doi":"10.2147/CCIDE.S479284","DOIUrl":"10.2147/CCIDE.S479284","url":null,"abstract":"<p><strong>Introduction: </strong>Root canal retreatment is carried out in cases where previous endodontic therapies failed and involves the removal of root canal filling materials, followed by cleaning, shaping, and obturating of the canals.</p><p><strong>Aims: </strong>: The objective of this study was to collect information regarding attitudes, methods, and materials employed during the non-surgical endodontic retreatment (NSER) by general dentists working in Sousse Governorate, Tunisia.</p><p><strong>Materials and methods: </strong>A descriptive cross-sectional survey was conducted among 147 general dentists working in the Sousse Governorate, Tunisia, from May to November 2021. Data were collected by sending a structured questionnaire to the dental practitioners through email. All the data were analyzed by using the SPSS 10 computer software.</p><p><strong>Results: </strong>A total of 96 dentists responded to this survey. The response rate was 63.5%, with a female predominance (53.2.3%). 81.2% of the respondents performed at least one non-surgical endodontic retreatment (NSER) weekly. Our study revealed that the mandibular first molar is the tooth that most often requires endodontic retreatment (83.5%). Half of the participants never used the rubber dam during this procedure. Moreover, the majority of respondents (61.9%) simultaneously used manual files and rotary nickel-titanium instruments for root canal desobturation. Most of the dentists (69.57%) systematically use solvents during root canal desobturation.</p><p><strong>Conclusion: </strong>Our survey highlights that the majority of general dentists have adequate knowledge about endodontic retreatment. Nevertheless, dentists are yet to start the application of these newer strategies towards the management of endodontic failures.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"349-357"},"PeriodicalIF":1.5,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11414638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Alternative of Molar Incisor Hypomineralisation for Young Permanent Teeth: A Scoping Review.","authors":"Claudia Nur Rizky Jayanti, Eriska Riyanti","doi":"10.2147/CCIDE.S479103","DOIUrl":"https://doi.org/10.2147/CCIDE.S479103","url":null,"abstract":"<p><strong>Background: </strong>Treatment of Molar-incisor hypomineralisation (MIH) poses significant challenges for pediatric dentists due to its varied clinical manifestations and treatment needs. Understanding and evaluating different treatment options can improve patient outcomes. This study aimed to analyze available evidence on treatment options for restoring MIH-affected young permanent teeth.</p><p><strong>Methods: </strong>This scoping review followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. A systematic literature search was conducted using Scopus, PubMed, and Science Direct databases, covering publications from 2014 to 2024. The search focused on therapies for young permanent teeth with MIH in children, employing predefined keywords and the Population, Concept, and Context framework.</p><p><strong>Results: </strong>A total of 20 studies were included from Turkiye, Brazil, Syria, Germany, Egypt, and India. Thirteen articles examined first molars, five focused on incisors, and two covered both. The population studied ranged from 6 to 18 years old, involving up to 281 children and between 30 to 326 teeth. The study provides insights into various management and treatment approaches for MIH-affected teeth, along with the effectiveness and long-term stability of different methods and materials.</p><p><strong>Conclusion: </strong>Materials such as resin infiltration, SDF, HVGI, full metal crowns, SSC, lithium disilicate, zirconia crowns, and CAD/CAM ceramic restorations offer greater longevity and require less retreatment in managing MIH-affected teeth.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"337-348"},"PeriodicalIF":1.5,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Analysis of the Quality of Root Canal Fillings of In Vivo Studies Conducted in Saudi Arabia and Worldwide: A Systematic Review.","authors":"Abdulmajeed Saeed Alshahrani, Ahmed Ali Alelyani, Sadun Mohammad Al Ageel Albeaji, Dalia AlHarith, Ahmed Abdullah A Al Malwi, Abdulrahman Abdullah Aldhbaan, Khaled Saleh J Alshehri, Alwaleed Essam Bakri, Abdullah Ahmed Ali Sahli, Wafa Hassan Alaajam, Mohammed M Al Moaleem","doi":"10.2147/CCIDE.S479321","DOIUrl":"https://doi.org/10.2147/CCIDE.S479321","url":null,"abstract":"<p><strong>Aim: </strong>Root canal treatment (RCT) is a common procedure practiced daily by dentists worldwide. The current systematic review aimed to evaluate and compare clinical studies on the quality of root canal fillings (RCFs) carried out by dentists with different levels of experience conducted worldwide with those conducted specifically in Saudi Arabia (SA).</p><p><strong>Materials and methods: </strong>A full literature search was conducted in Clarivate Analytics' Web of Science, Elsevier's Scopus, Embase, CINHAL, and PubMed, without a restriction to studies published before January 2015. Also, a manual search was carried out by checking papers that may have been missed during the electronic search. The following keywords were used: [(quality of root canal filling(s)) OR (quality of root canal obturation)) and dental practitioners as (general dental practitioners; final year students; endodontist; specialist) AND (root canal obturation) OR (endodontic treatment)]. Parameters of the quality of RCFs, such as length, density, and taper, were assessed and counted.</p><p><strong>Results: </strong>A total of 13 worldwide and nine SA studies were included in this review, published between 2015 and 2023. Molars were the most treated teeth, at 42.3% and 40.2% for the worldwide and SA studies, respectively. Cases treated by final year students had the highest percentage, at 60.0% for both study groups. The percentages of acceptable quality, with regard to the length, density, and taper of RCFs, were 70.9%, 77.6%, and 84.3%, and 73.2%, 64.6%, and 67.8% for the worldwide and SA studies, respectively.</p><p><strong>Conclusion: </strong>The overall acceptable quality of RCFs was marginally higher in worldwide studies than in SA studies. Both prevalences can be considered as good, which indicates that the quality of RCFs is moving in the right direction.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"323-336"},"PeriodicalIF":1.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11407322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Management of Hereditary Gingival Fibromatosis: Case Series.","authors":"Hassina Shadab, Aisha Nawabi, Abdurrahman Anwari, Mohammad Bashir Nejabi, Elaha Somaya Ghafari, Sajeya Karimi, Mohammad Eissa Ahmadi","doi":"10.2147/CCIDE.S480490","DOIUrl":"https://doi.org/10.2147/CCIDE.S480490","url":null,"abstract":"<p><p>Hereditary gingival fibromatosis (HGF) is an uncommon genetic condition marked by gradual and progressive overgrowth of fibrous tissue in the gums, which is benign in nature. It is a genetic disorder inherited in an autosomal dominant pattern, known for its considerable genetic diversity. The marginal, attached, and interdental gingivae are affected by this condition. The affected area appears pink, does not bleed easily, and exhibits a firm, fibrotic texture. Additionally, it displays a hard, widespread nodular growth that is smooth to stippled and has little bleeding tendency. Nevertheless, in certain instances, the enlargement may feel so dense and firm that it resembles bone upon palpation. Accordingly, esthetics and functions related to a healthy gingiva is also affected. The choice of treatment modality often depends on factors such as the severity of gingival overgrowth, available resources, and patient-specific considerations. Laser techniques and electrosurgery have emerged as valuable options, providing benefits like reduced discomfort and enhanced precision. However, traditional surgical methods remain highly effective, particularly when advanced technologies are not available. This article reports on three cases of hereditary gingival fibromatosis (HGF) treated with conventional gingivectomy, flap procedures, and resective osseous surgery (osteoplasty and osteotomy). The aim is to support the efficacy of these interventions in addressing patient complaints and preparing the groundwork for managing additional issues, such as speech and mastication difficulties, delayed eruption of permanent teeth, and malocclusion. The surgical treatment led to significant improvements: masticatory function was markedly enhanced, aesthetic outcomes were notably better, and oral hygiene significantly improved. Additionally, the procedures created favorable conditions for future treatments, including orthodontics, implants, or prosthetics, by providing a more manageable and functional oral environment.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"307-319"},"PeriodicalIF":1.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Fiber-Reinforced Composite Placement Site on Fracture Resistance of Premolar Teeth: an in vitro Study [Letter].","authors":"Arni Irawaty Djais, Hasanuddin Thahir, Ernie Maduratna Setiawatie","doi":"10.2147/CCIDE.S494169","DOIUrl":"https://doi.org/10.2147/CCIDE.S494169","url":null,"abstract":"","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"321-322"},"PeriodicalIF":1.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Lemon Verbena (<i>Cymbopogon citratus</i>) in Oral Candidiasis: A Systematic Review.","authors":"Katherine Cuenca-León, Miriam Lima-Illescas, Edisson-Mauricio Pacheco-Quito, Eleonor Vélez-León, Aránzazu Zarzuelo-Castañeda","doi":"10.2147/CCIDE.S478181","DOIUrl":"https://doi.org/10.2147/CCIDE.S478181","url":null,"abstract":"<p><p>The rise of phytotherapy has enabled the utilization of various plant species for medicinal purposes, such as <i>Cymbopogon citratus</i> (<i>C. citratus</i>), providing solutions for oral pathologies, such as oral candidiasis. The PubMed, Web of Science, Scopus, and SciELO databases were searched. In vivo and in vitro studies on the action of <i>C. citratus</i> against oral candidiasis were included, and ROBINS-I was used to determine study quality and risk of bias. The search yielded 1922 articles, of which 10 met the inclusion criteria. Limited scientific evidence exists regarding the use of <i>C. citratus</i> for oral candidiasis. However, studies have indicated its potent antifungal effects. Further studies, preferably clinical trials, are necessary to confirm this effect and to enable its clinical use as a therapeutic option.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"295-305"},"PeriodicalIF":1.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Evaluation of the Effect of Nanohydroxyapatite Lozenge on the pH of Dental Plaque.","authors":"Sunil Mankar, Bennett T Amaechi, Kannan Kanthaiah, Nahid Iftikhar, Amos C Obiefuna","doi":"10.2147/CCIDE.S472427","DOIUrl":"10.2147/CCIDE.S472427","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the influence of nanohydroxyapatite-containing (nanoHAP) lozenge on plaque pH following sucrose intake.</p><p><strong>Patients and methods: </strong>Sixteen adult subjects were enrolled in this double-blind crossover study composed of four interventions: (1) 10% w/v sucrose solution, (2) 10% w/v sorbitol solution, (3) nanoHAP lozenge, and (4) 10% w/v sucrose solution challenge followed by nanoHAP lozenge. Following the determination of each subject's resting plaque pH, the pH was measured at different time intervals from 3 to 30 minutes from the start of intervention, with 7 days interval between the applications of different interventions. The data were analyzed using the analysis of variance and Tukey's test (α < 0.05).</p><p><strong>Results: </strong>While sorbitol produces no change in plaque pH, nanoHAP-lozenge increased the plaque pH from a baseline of 7.0 ± 0.3 (mean ± sd) to 7.8 ± 0.2 (mean ± sd) within 30 minutes. Sucrose lowered the plaque pH from a baseline of 7.0 ± 0.4 (mean ± sd) to the lowest minimum of 5.1 ± 0.1 (mean ± sd) at the 7^th minute, rising above the critical pH of enamel dissolution (5.5) at 12^th minute and the baseline pH in more than 30 minutes. With lozenge intervention following sucrose challenge, plaque pH rose to 5.5 in 8 min, and to the baseline pH in 24 min. The cH area (Hydrogen ion concentration area) produced by sucrose (1.82 sq. units) was significantly (p < 0.05) greater than that produced when sucrose was challenged with lozenge (0.48 sq. units).</p><p><strong>Conclusion: </strong>Nanohydroxyapatite-containing lozenge increased plaque pH, reduced plaque pH drop in the presence of sucrose, and facilitated the rapid recovery of plaque pH after sucrose intake.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"285-293"},"PeriodicalIF":1.5,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11380479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Ethical Dilemma of Tooth Extraction on Patient Request [Letter].","authors":"Yahya Fayaz, Shahab Uddin Ahmadi, Said Ahmad Sorosh Miri","doi":"10.2147/CCIDE.S492709","DOIUrl":"10.2147/CCIDE.S492709","url":null,"abstract":"","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"283-284"},"PeriodicalIF":1.5,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agreement Between Clinical and Histopathological Diagnoses of Oral and Maxillofacial Lesions and Influencing Factors: A Five-Year Retrospective Study.","authors":"Amal Mohammed Sindi, Khalid Aljohani","doi":"10.2147/CCIDE.S473583","DOIUrl":"10.2147/CCIDE.S473583","url":null,"abstract":"<p><strong>Purpose: </strong>Diagnosing oral and maxillofacial lesions is a multi-step, multidisciplinary process. If a clinical diagnosis is achievable, then a histopathological diagnosis is indicated to support and confirm the diagnosis. Histopathological examination of tissue biopsies is therefore an essential part of the diagnosis and/or treatment plan. The purpose of this study was to investigate the agreement between the clinical and histopathological diagnoses of oral and maxillofacial lesions and the patient, lesion, and healthcare provider factors that may affect this agreement.</p><p><strong>Patients and methods: </strong>This was an observational, cross-sectional study of all patients who had been referred to the Oral Pathology Central Laboratory at the Faculty of Dentistry and University Dental Hospital at King Abdulaziz University in Jeddah, Saudi Arabia, between 2018 and 2022 for diagnosis of oral and maxillofacial lesions. Data extracted included information about the referring dental provider such as their clinical experience (number of years), specialty, certification, and education. Agreement between the clinical and histopathological diagnoses was evaluated, and logistic regression was used to assess provider characteristics associated with the accuracy of diagnosis.</p><p><strong>Results: </strong>The clinical and pathological diagnoses were concordant in 44.1% (n=378) of cases, and concordance was highest for odontogenic tumors (72.7%, n=24), significantly higher than for inflammatory lesions (37.3%, n=111). The anatomical locations with the highest diagnostic accuracy were the ventral surface of the tongue (71.4%, n=5), followed by the lips (52.6%, n=20). Patient age and sex and the dentist's years of experience were not associated with diagnostic agreement (p=0.2, p=0.9, and p=0.08, respectively). However, concordant diagnoses were significantly associated with the dentist's rank (p=0.02) and specialty (p=0.01). Clinical diagnoses made by oral surgeons at the time of biopsy were 1.6-times more likely (p=0.01) to agree with the pathological diagnosis compared with those made by other specialties when controlling for education, certification, and years of experience.</p><p><strong>Conclusion: </strong>These data are a reminder that a clinical diagnosis alone is not sufficient to secure the final diagnosis and to plan treatment. Histopathological examination remains essential for most oral and maxillofacial lesions.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"273-282"},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Fiber-Reinforced Composite Placement Site on Fracture Resistance of Premolar Teeth: An in vitro Study.","authors":"Raghad Tariq AlJarboua, Reem Ahmad Alshihry, Haya Othman Alkhaldi, Fadak Hussain Al Marar, Mohammed A Aljaffary, Mohammed L Almana, Abdulrahman A Balhaddad, Othman Alkhateeb","doi":"10.2147/CCIDE.S461134","DOIUrl":"10.2147/CCIDE.S461134","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the fracture behavior of upper premolars with deep MOD cavities that were restored with Ribbond resin-reinforced fibers (FRCs) placed in different orientations.</p><p><strong>Methods: </strong>A total of 54 extracted maxillary premolars were randomly divided into nine groups. The experimental groups underwent MOD cavity preparation with or without root canal treatment, followed by FRCs placed in the pulpal floor, proximal walls, or both. Fracture resistance was tested using an Instron Machine. The samples were visually inspected to analyze the fracture mode.</p><p><strong>Results: </strong>The highest fracture resistance was observed in intact teeth (1299.98 ± 284.66 MPa). Placing Ribbond fibers in the pulpal floor (1155.86 ± 244.21 MPa) or the proximal walls (1077.56 ± 260.60 MPa) significantly improved fracture resistance (<i>p</i>= <0.05), compared to cavities restored with only resin composite (804.58 ± 93.34 MPa). However, placing Ribbond fibers in both the pulpal and proximal walls did not enhance fracture resistance. In the MOD-RCT groups, fracture resistance was improved only when Ribbond fibers were placed in the pulpal floor and the proximal walls. Fracture mode analysis revealed a combined fracture in most of the groups.</p><p><strong>Conclusion: </strong>This study concluded that using FRCs significantly improved the fracture resistance of MOD cavities in premolars and revealed that the placement site could be a determinant factor.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"16 ","pages":"255-266"},"PeriodicalIF":1.5,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11244617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}