Clinical Otolaryngology最新文献

{"title":"Nasal Obstruction Is Reduced 5–7 Years After Radiofrequency Turbinate Reduction: Results From a Retrospective Observational Cohort Study","authors":"Veronica Ahlund,&nbsp;Pål Rosholm Comstedt,&nbsp;Maria Värendh,&nbsp;Pernilla Sahlstrand-Johnson","doi":"10.1111/coa.70148","DOIUrl":"10.1111/coa.70148","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Nasal obstruction, often caused by structural and inflammatory conditions, is prevalent and significantly impacts health-related quality of life. Radiofrequency Turbinate Reduction (RFTR) is a widely employed treatment for inferior turbinate hypertrophy, yet evidence of its long-term effectiveness remains limited. This study aimed to assess the patient-perceived long-term outcomes of RFTR in patients with nasal obstruction, focusing on quality of life as measured by the Sinonasal Outcome Test-22 (SNOT-22) and to identify baseline factors predicting surgical outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cohort of 198 patients aged ≥ 18 years who underwent RFTR for nasal obstruction filled out the SNOT-22 questionnaire and additional questions preoperatively and 5–7 years postoperatively. Predictors of persistent nasal obstruction after RFTR were identified using logistic regression analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>SNOT-22 scores significantly decreased from score mean 43.14 (0–104, min–max) to 34.66 (0–101) at the 5- to 7-year follow-up (<i>p</i> &lt; 0.001), with notable improvements in the rhinologic and sleep function domains. However, baseline symptoms of ‘thick nasal discharge’ and ‘poor sleep quality’ were associated with a higher relative risk and higher odds ratio of continued nasal obstruction after adjustment for confounders. These baseline symptoms remained significant predictors of persistent nasal obstruction postoperatively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Radiofrequency Turbinate Reduction reduced nasal obstruction and also showed long-term efficacy in improving health-related quality of life after long-term outcome, with most patients reporting positive outcomes. Patients with severe baseline symptoms of thick nasal discharge and poor sleep quality may experience less favourable outcomes, possibly due to comorbidities. These findings highlight the potential of SNOT-22 to identify patients at risk of persistent symptoms post-RFTR.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"914-922"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70148","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148583513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retronasal Olfactory Function After Olfactory Training: A Prospective Single-Arm Study","authors":"Michal Pieniak,&nbsp;Maher Abou Nasr,&nbsp;Selin Bayindir,&nbsp;Thomas Hummel","doi":"10.1111/coa.70156","DOIUrl":"10.1111/coa.70156","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Retronasal olfaction is essential for aroma perception. Its impairment in individuals with olfactory dysfunction (OD) negatively affects dietary behaviour and quality of life. Regular exposure to odours in a form of olfactory training (OT) is used to rehabilitate the sense of smell. However, retronasal recovery following OT remains insufficiently characterised.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To verify whether OT improves retronasal odour identification and whether such improvement is related to orthonasal odour identification recovery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Prospective, single-arm clinical study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Fifty-three patients with OD (predominantly post-COVID-19) completed at least 3 months of OT (conducted bi-daily with four odours). Retronasal function was assessed with the ThreeT test and orthonasal function with the Sniffin’ Sticks battery before and after training.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>OT significantly improved both retronasal (9.40 ± 0.42 vs. 10.85 ± 0.48; <i>p</i> &lt; 0.001) and orthonasal odour identification (8.75 ± 0.50 vs. 10.53 ± 0.50; <i>p</i> &lt; 0.001). Changes in retronasal performance positively, moderately correlated with changes in orthonasal identification (<i>r</i> = 0.38, <i>p</i> = 0.006). Clinically meaningful retronasal improvement was associated with a higher likelihood of orthonasal recovery, <i>χ</i>\u0000 ²(1) = 5.08, <i>p</i> = 0.024; OR = 4.00 (95% CIs: 1.16–13.83).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>OT improves retronasal odour identification. The mechanisms of orthonasal and retronasal recovery may be partially overlapping.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"938-943"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70156","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148724337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severity of Xerostomia and Its Correlation With Self-Perceived Voice Handicap and Mental Well-Being in Patients With Voice Disorders","authors":"Abdul-Latif Hamdan,&nbsp;Lana Ghzayel,&nbsp;Zeina Maria Semman,&nbsp;Ghena Lababidi,&nbsp;Valerie Sarkis,&nbsp;Ibana Carapiperis,&nbsp;Omar Aboul Hosn,&nbsp;Jonathan Abou Chaar,&nbsp;Nijad Zeineddine,&nbsp;Georges M. Zaytoun","doi":"10.1111/coa.70141","DOIUrl":"10.1111/coa.70141","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate the severity of xerostomia in patients with hoarseness and its correlation with self-perceived voice handicap, anxiety, and depression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methodology</h3>\u0000 \u0000 <p>All patients who presented to the Voice unit between February and September 2025 were invited to participate in this study. They were asked to complete three questionnaires: Xerostomia Inventory (XI) questionnaire, Generalized Anxiety Disorder-7 scale (GAD-7), and the Patient Health Questionnaire-9 (PHQ-9).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 75 subjects participated in this study, including 38 patients and 37 controls matched by age and gender. The patient subgroup included 20 males and 18 females. The mean age was 44.05 ± 13.31 years. The mean XI questionnaire score in the patient subgroup was 18.18 ± 7.63 compared to 14.43 ± 3.42 in the control subgroup (<i>p</i> = 0.048). The mean GAD-7 score in the patient subgroup was 13.55 ± 14.20 compared to 5.27 ± 4.92 in the control subgroup, and the mean PHQ-9 score in the patient subgroup was 7.74 ± 8.07 compared to 4.43 ± 3.83 in the control subgroup. There was a moderately significant correlation between the Voice Handicap Index-10 (VHI-10) and XI scores (<i>r</i> = 0.393, <i>p</i> &lt; 0.001). There was also a significant moderate correlation between XI questionnaire, and GAD-7, and PHQ-9 scores (<i>r</i> = 0.441, <i>p</i> &lt; 0.001, and <i>r</i> = 0.454, <i>p</i> &lt; 0.001, respectively).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Patients with dysphonia are more likely to complain of oral dryness compared to healthy controls. The severity of xerostomia correlated significantly with patients' self-perceived hoarseness, anxiety, and depression.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"882-887"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148419540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjustable Vocal Implant System (VOIS) for Unilateral Vocal Fold Paralysis: Short-Term Outcomes From a 12-Patient Case Series","authors":"Sam Kebbe,&nbsp;Michael Keane,&nbsp;Chuanyu Gao,&nbsp;Yadsan Devabalan,&nbsp;Guan-Min Ho,&nbsp;Rohan Bidaye","doi":"10.1111/coa.70142","DOIUrl":"10.1111/coa.70142","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Unilateral vocal cord palsy (UVCP) significantly affects phonation and swallowing. While injection laryngoplasty and medialisation thyroplasty are effective, both may require revision. Vocal Implant System (VOIS; APrevent Biotech GmbH) is an adjustable titanium-silicone thyroplasty implant that allows postoperative modification, potentially reducing the need for further surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twelve patients, seven male and five female, underwent VOIS implantation. Voice outcomes were assessed pre- and postoperatively using the GRBAS scale and the Voice Handicap Index-10 (VHI-10).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The composite GRBAS score improved significantly from 9.0 ± 1.87 to 3.75 ± 2.49 (<i>p</i> = 0.0024). The VHI-10 decreased from 25.75 ± 9.36 to 14.92 ± 9.55 (<i>p</i> = 0.0093). No intra- or postoperative complications occurred. Two patients required postoperative implant volume adjustments—one performed in clinic and one under local anaesthetic in theatre.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The VOIS implant thyroplasty demonstrated significant improvement in both perceptual and patient-reported voice outcomes with a favourable safety profile. Larger, long-term studies are warranted to confirm its comparative efficacy and durability.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"902-907"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laryngeal Cancer Survival in Northern United Kingdom: A Multi-Centre Retrospective Observational Study","authors":"Amar Rajgor,&nbsp;Rhona Hurley,&nbsp;Catriona M. Douglas,&nbsp;Claire Paterson,&nbsp;James Moor,&nbsp;Shane Lester,&nbsp;Sara Sionis,&nbsp;Katherine Davies,&nbsp;James O’Hara,&nbsp;Gareth Inman,&nbsp;Terry Jones,&nbsp;David Winston Hamilton,&nbsp;Northern Head & Neck Alliance","doi":"10.1111/coa.70138","DOIUrl":"10.1111/coa.70138","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Laryngeal cancer incidence has risen globally, yet survival outcomes have shown limited improvement over recent decades. This study evaluated contemporary outcomes across multiple centres in Northern UK and examined stage- and treatment-specific survival.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Multi-centre retrospective observational study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting and Participants</h3>\u0000 \u0000 <p>Data were collected for 2028 patients with biopsy-proven squamous cell carcinoma of the larynx treated with curative intent between 2015 and 2021 across six tertiary head and neck cancer centres (Newcastle, Glasgow, Liverpool, Sheffield, Leeds, and Middlesbrough).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>Overall survival (OS) and disease-specific survival (DSS) were estimated using Kaplan–Meier analysis and compared using log-rank testing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Median follow-up was 40 months (mean age 66.8 years; 81% male). Overall mortality was 41% and disease-specific mortality 20%. Five-year OS declined with advancing stage: 72.0% (T1), 54.5% (T2), 50.6% (T3), and 45.2% (T4). In unadjusted analyses, surgery in T1 disease was associated with higher survival (5-year DSS 93.6% vs. 88.5%), while in advanced disease chemoradiotherapy was associated with the highest DSS (5-year DSS 70.2%), although differences were not statistically significant. No significant differences in DSS were observed across year of diagnosis (2015–2021).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Survival outcomes for laryngeal cancer remain poor and have shown limited improvement over time. These findings provide important real-world insights into contemporary outcomes and highlight the need for earlier detection, prevention strategies, and prospective collaborative research to improve future outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"867-874"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70138","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of Systemic Immune-Inflammation and Inflammatory Response Indices in Vestibular Neuritis","authors":"Tuğba Tulacı,&nbsp;Mustafa Utku Akbaş,&nbsp;Hasan Çanakçı,&nbsp;Tarık Yetişir,&nbsp;Kamil Gökçe Tulacı,&nbsp;Haşmet Yazıcı,&nbsp;Gulendam Kayıkçı,&nbsp;Omer Hizli","doi":"10.1111/coa.70140","DOIUrl":"10.1111/coa.70140","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>This study investigated the relationship between vestibular neuritis and various systemic inflammatory indices—namely, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI) and the clinical severity of vestibular neuritis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 79 individuals were included: 41 patients with vestibular neuritis and 38 healthy controls. Systemic inflammatory parameters were calculated from complete blood count results, and their associations with disease severity—classified as mild (≤ 4 days of nystagmus) or severe (&gt; 4 days of nystagmus)—were analysed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>NLR, SII and SIRI were significantly higher in the severe vestibular neuritis group compared to controls (<i>p</i> = 0.032, <i>p</i> = 0.019 and <i>p</i> = 0.042, respectively), while the mild group showed no significant difference relative to either controls or the severe group. SII demonstrated the highest predictive value for severe vestibular neuritis (AUC = 0.66), showing superior discriminative performance compared with NLR and SIRI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Although the pathogenesis of vestibular neuritis remains unclear, the elevation of NLR, SII and SIRI in more severe cases suggests an inflammatory involvement. Their association with severe disease may support future research into whether these markers could help identify patients who are more likely to benefit from anti-inflammatory treatment strategies. However, further prospective studies are needed to clarify the clinical relevance of these findings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"855-860"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70140","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148389778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-Effectiveness of Radiofrequency Ablation for Benign Non-Functioning Thyroid Nodules: A Systematic Review","authors":"Sam P. J. van Dijk,&nbsp;Matthew M. K. Blanco,&nbsp;Ali Akhavan,&nbsp;Jessica Liu McMullin,&nbsp;G. Scott Gazelle,&nbsp;Mohammad S. Jalali,&nbsp;Jagpreet Chhatwal,&nbsp;Yinin Hu,&nbsp;Tessa M. van Ginhoven,&nbsp;Rajshri M. Gartland,&nbsp;Carrie Cunningham","doi":"10.1111/coa.70150","DOIUrl":"10.1111/coa.70150","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This systematic review tests the hypothesis that radiofrequency ablation (RFA) for benign non-functioning thyroid nodules is associated with favourable cost-effectiveness compared with surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A systematic literature search of multiple databases (Embase, Medline, Web of Science, and Cochrane Central) was conducted through 16 May 2025, with no restrictions on publication date or language. Full economic evaluations comparing RFA with alternative management strategies were included in the primary synthesis. Secondary narrative synthesis included studies reporting cost data without formal cost-effectiveness modelling. All costs were converted to 2021 US dollars to enable cross-study comparability. Incremental cost-effectiveness ratios (ICERs), net monetary benefit (NMB), and net health benefit (NHB) were calculated where data allowed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirteen studies met the inclusion criteria: 3 full economic evaluations and 10 descriptive cost studies. All compared RFA to surgery. In the primary synthesis, two studies reported ICERs for RFA versus surgery, which ranged from –$14 994 (reflecting a lower cost and greater effectiveness for RFA) to $98 858 per QALY gained, with substantial variation in model design and assumptions. Post hoc estimates of NMB and NHB generally favoured RFA at $50 000 and $100 000 willingness-to-pay thresholds. In the narrative synthesis, 8 of 10 studies reported lower total costs for RFA (median: $2499) compared to surgery (median: $3579). Methodological heterogeneity limited comparability. Overall certainty of economic evidence was rated as low.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>RFA may be a cost-effective alternative to surgery for benign thyroid nodules, but current economic evidence is limited and of low certainty.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"805-818"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148663494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy and Safety of Turbinate Surgery for Chronic Rhinitis: A Systematic Review and Network Meta-Analysis","authors":"Do Hyun Kim,&nbsp;David W. Jang,&nbsp;Se Hwan Hwang","doi":"10.1111/coa.70159","DOIUrl":"10.1111/coa.70159","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the treatment outcomes of various turbinate surgeries in patients with chronic rhinitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design and Setting</h3>\u0000 \u0000 <p>A systematic review and meta-analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>A systematic search was conducted using six databases. Treatment conditions included six surgical interventions—coblator-assisted turbinoplasty (CAT), laser ablation, microdebrider-assisted turbinoplasty (MAT), radiofrequency tissue volume reduction (RFVTR), submucosal diathermy (SMD) and partial inferior turbinectomy (PIT)—and a reference intervention (submucosal resection). Outcomes included symptom scores, turbinate size, operative time and surgery-related adverse effects such as atrophic changes, crusting, nasal dryness, mucosal tearing, revision rate and postoperative bleeding. Both pairwise and network meta-analyses were performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>MAT was associated with better outcomes across most parameters but showed a higher risk of mucosal tearing. SMD was associated with lower effectiveness in alleviating nasal obstruction at 6–12 months and laser ablation was associated with reduced effectiveness in decreasing turbinate size. RFVTR exhibited the shortest operative time and was associated with advantages in minimising nasal dryness and preserving the mucosa. Regarding adverse effects, laser ablation was associated with an increased risk of atrophic rhinitis, PIT with a higher incidence of crusting and dryness and SMD with a greater likelihood of requiring revision surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>MAT was associated with relatively favourable outcomes across most parameters; however, it also showed a higher risk of mucosal tearing. RFVTR was associated with advantages in minimising nasal dryness and preserving mucosal integrity. Both SMD and laser ablation were associated with comparatively limited efficacy and relatively higher rates of adverse effects.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"831-848"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modifiable Risk Factors and Hearing Loss: The National Health and Nutrition Examination Survey 1999–2020","authors":"Yulu Zheng,&nbsp;Tingting Li,&nbsp;Zhiyuan Wu,&nbsp;Yahong Zhu,&nbsp;Zheng Guo,&nbsp;Xingang Li","doi":"10.1111/coa.70153","DOIUrl":"10.1111/coa.70153","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To explore the associations between major modifiable risk factors and hearing loss.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This serial cross-sectional study was conducted within the National Health and Nutrition Examination Survey 1999–2020 in the United States. Associations were assessed using modified Poisson regression and within-sample population attributable fraction (PAF).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eight thousand seven hundred and seventy adults aged 40–85 years were included in the analyses, the mean (SD) age was 58.0 (11.7) years, with 4002 men (45.6%). Hearing loss was associated with low educational attainment with prevalence ratio 1.23, 95% confidence interval (1.15, 1.31); low income 1.11 (1.04, 1.19); diabetes 1.10 (1.03, 1.18); HDL-C dyslipidaemia 1.13 (1.06, 1.21); obesity 1.08 (1.01, 1.15) and tobacco use 1.11 (1.04, 1.19). Within our analysis, over 25% of hearing loss cases were attributed to modifiable risk factors, with low education or income, HDL-C dyslipidaemia, obesity and tobacco use being the leading contributors, though relative rankings varied slightly in survey-weighted analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Hearing promotion policies should prioritise related modifiable factors to reduce the burden of hearing loss.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"929-937"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic Prophylaxis and Surgical Site Infections in Septoplasty","authors":"Sara Sainio,&nbsp;Elin Fierens,&nbsp;Antti Mäkitie,&nbsp;Markus Lilja,&nbsp;Morag Tolvi,&nbsp;Marie Lundberg","doi":"10.1111/coa.70145","DOIUrl":"10.1111/coa.70145","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Surgical site infection is one of the most common complications of septoplasty. The use of antibiotic prophylaxis has been debated for years. Since the practice at our centre has shifted towards a more frequent use of prophylactic antibiotics in septoplasties, our aim was to review its use and effect on the postoperative infection rate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively reviewed the medical records of all adult patients who had undergone septoplasty at the Helsinki University Hospital (Helsinki, Finland) during 2019–2023. Patient and surgery characteristics, use of surgical antibiotic prophylaxis, surgical site infections and their management were reviewed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The series consisted of 1169 septoplasties, and antibiotic prophylaxis was used in 90.1% of the cases. A postoperative infection was diagnosed in 1.9%. Longer operative time and the use of silicone splints were associated with a higher risk of postoperative infections (<i>p</i> = 0.007 and <i>p</i> = 0.03, respectively). There was no significant difference in the infection rate between those who received preoperative antibiotic prophylaxis and those who did not. Among those using a preoperative course of topical antibiotic cream, no infections were seen. Compared with previous studies on septoplasty infections at our centre, the infection rate has decreased whilst the use of antibiotic prophylaxis has increased.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Based on the present results, antibiotic prophylaxis does not affect postoperative infection rate after septoplasty. A preoperative course of nasal mupirocin seems to be a promising and less harm-causing form of prophylaxis. To confirm our results, there is a need for analysis of larger patient cohorts and prospective, controlled studies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":"51 6","pages":"888-893"},"PeriodicalIF":1.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/coa.70145","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148444842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}