Clinical Journal of Gastroenterology最新文献_第4页

Arsenic and young liver: a case report of hepatic steatosis due to arsenic toxicity. 砷与年轻的肝脏：砷中毒导致肝脂肪变性的病例报告。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-08 DOI: 10.1007/s12328-024-02045-3

Cindy Khanh Nguyen, Meagan Alvarado, Won Jae Huh, Jennifer Batisti

引用次数: 0

A case of situs inversus totalis with hemosuccus pancreaticus due to intrapancreatic pseudocyst perforation of the common hepatic artery treated with a vascular stent graft. 一例因胰腺内假性囊肿导致肝总动脉穿孔而引起的全瘫伴胰腺血肿，采用血管支架移植治疗。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-08 DOI: 10.1007/s12328-024-02046-2

Ko Tomishima, Hironao Okubo, Daiki Abe, Shunsuke Nakamura, Takumi Okuaki, Tomonori Yamauchi, Koichi Ito, Yuka Fukuo, Takahiro Yamamoto, Hiroyuki Isayama

{"title":"A case of situs inversus totalis with hemosuccus pancreaticus due to intrapancreatic pseudocyst perforation of the common hepatic artery treated with a vascular stent graft.","authors":"Ko Tomishima, Hironao Okubo, Daiki Abe, Shunsuke Nakamura, Takumi Okuaki, Tomonori Yamauchi, Koichi Ito, Yuka Fukuo, Takahiro Yamamoto, Hiroyuki Isayama","doi":"10.1007/s12328-024-02046-2","DOIUrl":"https://doi.org/10.1007/s12328-024-02046-2","url":null,"abstract":"Hemosuccus pancreaticus (HP) is characterized by gastrointestinal bleeding from the papilla of Vater via the pancreatic duct. In this report, we describe a case of HP due to arterial perforation in a pancreatic pseudocyst and discuss the computed tomography (CT) findings and efficacy of stent graft placement. A 64-year-old man with a history of heavy alcohol use, situs inversus totalis, and total gastrectomy was hospitalized with hematochezia. Enhanced CT revealed a pseudoaneurysm in the common hepatic artery (CHA) with mildly high density in the main pancreatic duct. Subsequent CT revealed an enlarged cystic lesion with inflow of contrast medium. Angiography confirmed blood flow from the CHA into the pancreatic pseudocyst, and the patient was diagnosed with HP due to intrapancreatic pseudocyst perforation of the CHA pseudoaneurysm. Coil packing into the pseudocyst failed to block the blood flow, and a covered stent graft was placed into the CHA. The patient had an uneventful clinical course. The identification of a pseudoaneurysm and a high-density area in the main pancreatic duct on enhanced CT and changes in the pancreatic cyst diameter may indicate the acute phase of HP, and stent grafting is an effective treatment for intracystic arterial perforation.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BRAF-mutant mismatch repair deficient invasive colon cancer regressing to sessile serrated lesion. BRAF突变错配修复缺陷浸润性结肠癌向无柄锯齿状病变发展。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-13 DOI: 10.1007/s12328-024-02006-w

Kenshi Matsuno, Hideaki Miyamoto, Miki Shimoda, Ryosuke Gushima, Katsuya Nagaoka, Mayuko Ohuchi, Yuji Miyamoto, Kohei Ohkura, Yoshiki Mikami, Yasuhito Tanaka

{"title":"BRAF-mutant mismatch repair deficient invasive colon cancer regressing to sessile serrated lesion.","authors":"Kenshi Matsuno, Hideaki Miyamoto, Miki Shimoda, Ryosuke Gushima, Katsuya Nagaoka, Mayuko Ohuchi, Yuji Miyamoto, Kohei Ohkura, Yoshiki Mikami, Yasuhito Tanaka","doi":"10.1007/s12328-024-02006-w","DOIUrl":"10.1007/s12328-024-02006-w","url":null,"abstract":"A 69-year-old female was presented with a history of sigmoid colon cancer, uterine cancer, and intrahepatic carcinomas. After computed tomography revealed a disseminated nodule located in the peritoneum, colonoscopy demonstrated a rather flat-to-slightly elevated lesion with a depressed area located in the ascending colon. The flat component showed color similar to its surrounding area, and the depressed area showed redness and an expanded appearance. We obtained a biopsy specimen from the depressed area, and microscopic examination revealed well-differentiated adenocarcinoma, which was immunohistochemically positive for BRAF V600E-mutated and PMS2 proteins, and showed loss of MSH2 and MSH6 protein expressions. These findings suggested the lesion to have transformed from a sessile serrated lesion (SSL) to mismatch repair (MMR) deficient colon cancer. The patient underwent surgical removal of the nodule, which interpreted as metastasis of intrahepatic cholangiocarcinoma histopathologically. After postoperative chemotherapy, the follow-up colonoscopy revealed only the flat portion of the lesion without depressed area. Consequently, we performed an endoscopic resection, and microscopic examination confirmed the existence of BRAF V600E-mutated protein-positive and MMR protein-retained SSL without residual carcinoma. This is the first report of BRAF-mutant and MMR-deficient colon cancer, in association with SSL, showing regression.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of pancreatic body cancer with disappearance of the dilated pancreatic duct on the tail side during preoperative treatment. 一例在术前治疗期间尾侧扩张的胰管消失的胰体癌。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-06-23 DOI: 10.1007/s12328-024-02005-x

Yusuke Okamura, Ken Fukumitsu, Tatsuya Okishio, Yuri Kanaya, Yasuhiro Saito, Ryo Kudo, Michina Morioka, Shinsuke Shibuya, Toshihide Yamaoka, Dai Manaka

{"title":"A case of pancreatic body cancer with disappearance of the dilated pancreatic duct on the tail side during preoperative treatment.","authors":"Yusuke Okamura, Ken Fukumitsu, Tatsuya Okishio, Yuri Kanaya, Yasuhiro Saito, Ryo Kudo, Michina Morioka, Shinsuke Shibuya, Toshihide Yamaoka, Dai Manaka","doi":"10.1007/s12328-024-02005-x","DOIUrl":"10.1007/s12328-024-02005-x","url":null,"abstract":"This is a case of a 67-year-old woman diagnosed with a 35-mm pancreatic body cancer with a chief complaint of epigastric discomfort. Computed tomography demonstrated invasion of the common hepatic artery, portal vein, and stomach, and chemotherapy was initiated for locally advanced pancreatic cancer. After 9 months of chemotherapy, the tumor remained stable on imaging, and the tumor markers were within the normal range. After additional chemoradiotherapy, the patient underwent a conversion surgery, a pancreaticoduodenectomy. Magnetic resonance cholangiopancreatography (MRCP) at the time of diagnosis demonstrated main pancreatic duct (MPD) dilatation on the tail side of the tumor; however, most of the MPD signal disappeared on MRCP after chemotherapy. Surgical findings failed to identify MPD on the first pancreatic resection plane, and additional resection was conducted; however, no MPD was found. As a pancreatic duct anastomosis was not available, pancreatic reconstruction was selected for pancreaticogastric anastomosis using the invagination method. Pathologically, the pancreatic tissue on the tail side of the tumor was replaced by fibrotic tissue, and MPD could not be identified. To the best of our knowledge, this is the first case report of the disappearance of a dilated pancreatic duct on the tail side accompanied by exocrine tissue loss during preoperative treatment for pancreatic cancer.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pancreatico-renal fistula associated with pancreatic cysts caused by type 1 autoimmune pancreatitis. 1型自身免疫性胰腺炎引起的胰腺囊肿伴发的胰肾瘘。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-06-26 DOI: 10.1007/s12328-024-02008-8

Kensuke Takuma, Ai Fujimoto, Naoki Okano, Akihide Hayashi, Kensuke Hoshi, Yoichiro Sato, Yusuke Kimura, Yoshinori Igarashi, Kensuke Sakamoto, Takahisa Matsuda

引用次数: 0

Diaphragmatic and pericardial reconstruction using a Gore-Tex^® patch in a patient with an invasive liver malignancy. 使用 Gore-Tex® 补丁为一名侵袭性肝脏恶性肿瘤患者重建膈肌和心包。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-23 DOI: 10.1007/s12328-024-02017-7

Yusuke Matsune, Takeshi Aoki, Yoshihiko Tashiro

{"title":"Diaphragmatic and pericardial reconstruction using a Gore-Tex® patch in a patient with an invasive liver malignancy.","authors":"Yusuke Matsune, Takeshi Aoki, Yoshihiko Tashiro","doi":"10.1007/s12328-024-02017-7","DOIUrl":"10.1007/s12328-024-02017-7","url":null,"abstract":"The Gore-Tex® polytetrafluoroethylene patch is one of the most used prostheses for diaphragm, vessel, and pericardial reconstruction. It is strong, flexible, and relatively inexpensive and can be fitted to match the size of the resected area. In addition, it can be used to reconstruct the pericardium and diaphragm following resection to treat diffuse malignant pleural mesothelioma or repair large hiatal hernias. However, the use of polytetrafluoroethylene for hepatocellular carcinoma with diaphragmatic and pericardial invasion has not yet been reported. We report the case of a 72-year-old man with hepatocellular carcinoma with diaphragmatic and pericardial invasion. Subsequently, laparotomic liver subsegmentectomy of segment 3 and resection of the diaphragm and pericardium were performed. The defects were successfully reconstructed using the polytetrafluoroethylene patch, without postoperative complications. This is the first report describing a case of invasive liver malignancy that required simultaneous diaphragmatic and pericardial reconstruction using a polytetrafluoroethylene patch, indicating that the polytetrafluoroethylene patch could effectively and directly treat invasive liver malignancies.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A suspected case of serum IgG4-negative type 1 autoimmune pancreatitis detected due to localized pancreatic duct narrowing: a case report. 一例疑似因局部胰管狭窄导致血清 IgG4 阴性的 1 型自身免疫性胰腺炎病例：病例报告。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-06-04 DOI: 10.1007/s12328-024-01993-0

Karen Kimura, Kazuya Koizumi, Sakue Masuda, Makomo Makazu, Jun Kubota, Shinichi Teshima

{"title":"A suspected case of serum IgG4-negative type 1 autoimmune pancreatitis detected due to localized pancreatic duct narrowing: a case report.","authors":"Karen Kimura, Kazuya Koizumi, Sakue Masuda, Makomo Makazu, Jun Kubota, Shinichi Teshima","doi":"10.1007/s12328-024-01993-0","DOIUrl":"10.1007/s12328-024-01993-0","url":null,"abstract":"A 50-year-old woman was referred to our hospital with elevated serum amylase levels. Physical examination revealed no jaundice or abdominal tenderness. Serum IgG4 was negative. Computed tomography revealed a localized pancreatic duct narrowing in the pancreatic head, with caudal pancreatic duct dilation and an intraductal papillary mucinous neoplasm. Pancreatic enlargement was not observed. Endoscopic ultrasonography (EUS) showed a small hypoechoic mass. Although EUS-guided, fine-needle aspiration was performed, no diagnosis was established. Endoscopic retrograde pancreatography showed a localized narrowing in the main pancreatic duct of the pancreatic head. A biopsy of the narrowing was performed through the minor papilla because of difficult access from the major papilla. The specimen showed the infiltration of numerous IgG4-positive plasma cells, suggesting type 1 autoimmune pancreatitis (AIP). Six months later, magnetic resonance cholangiopancreatography revealed improvement in the narrowing without specific treatment. The patient presented with localized narrowing of the pancreatic duct and caudal duct dilation, which was distinct from pancreatic cancer. Diagnostic difficulties arose from negative serum IgG4 results, the lack of typical imaging characteristics of AIP, and failure to meet the AIP criteria according to the relevant Japanese and international guidelines. However, AIP was suspected and surgery was successfully avoided through a biopsy.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relapsing sclerosing mesenteritis with multiple strictures of the small intestine. 复发性硬化性肠系膜炎伴多发性小肠狭窄。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-05-29 DOI: 10.1007/s12328-024-01989-w

Masashi Ohno, Atsushi Nishida, Takayuki Imai, Eri Tanaka, Kenichiro Takahashi, Toru Miyake, Masaji Tani, Ryoji Kushima, Osamu Inatomi

引用次数: 0

Sustained clinical and histopathological remission in a patient with eosinophilic esophagitis and type-2 comorbidities at 18 months after discontinuation of dupilumab. 一名患有嗜酸性粒细胞食管炎和 2 型合并症的患者在停用杜必鲁单抗 18 个月后，临床和组织病理学症状持续缓解。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI: 10.1007/s12328-024-02011-z

Víctor González-Uribe, Carlos Patricio Acosta Rodríguez-Bueno, Zaira Selene Mojica-González, Andrea Malagón-Liceaga, Martín Roberto Basile-Alvarez

{"title":"Sustained clinical and histopathological remission in a patient with eosinophilic esophagitis and type-2 comorbidities at 18 months after discontinuation of dupilumab.","authors":"Víctor González-Uribe, Carlos Patricio Acosta Rodríguez-Bueno, Zaira Selene Mojica-González, Andrea Malagón-Liceaga, Martín Roberto Basile-Alvarez","doi":"10.1007/s12328-024-02011-z","DOIUrl":"10.1007/s12328-024-02011-z","url":null,"abstract":"Eosinophilic esophagitis (EoE) is a chronic, allergen-mediated, type-2 inflammatory disease with the potential to significantly impact an individual's quality of life. Conventional treatments often result in varied responses, prompting the need for novel therapeutic approaches. We present the case of a 19-year-old male with a medical history marked by eosinophilic esophagitis, severe atopic dermatitis (AD), asthma, and allergic rhinitis. Despite undergoing diverse topical and systemic interventions to address his AD and EoE, the patient's symptoms persisted. However, following the initiation of dupilumab therapy-a dual IL-4 and IL-13 receptor antagonist-the patient experienced a substantial reduction in his Eczema Area and Severity Index score. Notably, a marked improvement was also seen regarding his symptoms of eosinophilic esophagitis. A subsequent esophageal biopsy revealed a significant decrease in eosinophilic inflammation, consistent with established clinical and histologic remission criteria. These findings corroborate the patient's reported relief from symptoms. This case underscores the potential efficacy of dupilumab as a promising therapeutic agent in managing eosinophilic esophagitis. Dupilumab offers a dual benefit of alleviating symptoms and achieving histologic and clinical remission. This novel approach presents a noteworthy advancement in the treatment of EoE.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11436466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prepyloric gastric antral muscular ring in an infant. 婴儿幽门前胃前肌环。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-30 DOI: 10.1007/s12328-024-02010-0

Jolanta B Norelli, Dawid Plaza, Johanna Monsalve Villamizar

引用次数: 0