Clinical Journal of Gastroenterology最新文献

Tubular adenoma at the hepatico-jejunal anastomosis in familial adenomatous polyposis (FAP) following pancreaticoduodenectomy: challenges in adenoma surveillance and management. 胰十二指肠切除术后家族性腺瘤性息肉病（FAP）肝空肠吻合处的管状腺瘤：腺瘤监测和管理的挑战。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-10-05 DOI: 10.1007/s12328-024-02048-0

Muhammad Ali Butt, Lyubov Tiegs, Rahul Karna, Justin Peltola, Mohammad Bilal

引用次数: 0

Variceal bleeding following treatment with atezolizumab plus bevacizumab in two patients with unresectable hepatocellular carcinoma. 两名无法切除的肝细胞癌患者在接受阿特珠单抗加贝伐单抗治疗后出现静脉曲张出血。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-08-16 DOI: 10.1007/s12328-024-02031-9

Teppei Matsui, Hidenari Nagai, Takanori Mukozu, Noritaka Wakui, Takahisa Matsuda, Yoshinori Igarashi

{"title":"Variceal bleeding following treatment with atezolizumab plus bevacizumab in two patients with unresectable hepatocellular carcinoma.","authors":"Teppei Matsui, Hidenari Nagai, Takanori Mukozu, Noritaka Wakui, Takahisa Matsuda, Yoshinori Igarashi","doi":"10.1007/s12328-024-02031-9","DOIUrl":"10.1007/s12328-024-02031-9","url":null,"abstract":"Bleeding-related adverse events may occur due to anti-vascular endothelial growth factors. Here, we report two cases of variceal rupture during atezolizumab plus bevacizumab (ATZ/BV) treatment for unresectable hepatocellular carcinoma (u-HCC).Case 1 involved a man in his 60 s with alcoholic liver cirrhosis (LC) and u-HCC. Seventy-four days after ATZ/BV administration, the patient was admitted for hematemesis. Upper esophagogastroduodenoscopy (EGD) revealed worsening of the esophageal varices (EVs) to F2 grade with active bleeding. Endoscopic variceal ligation successfully achieved hemostasis.Case 2 involved a man in his 70 s with alcoholic LC and u-HCC. The patient was admitted with hematemesis 114 days after ATZ/BV administration. During EGD, the EVs deteriorated to F3 grade, although hemostasis had already been achieved. The evaluation was discontinued during the observation stage because of the worsening hepatic reserve.Neither patient had EVs warranting prophylactic treatment before ATZ/BV administration, showed a partial tumor response, or had portal vein tumor thrombus. Both patients demonstrated increased total diameters of the collateral veins and splenic volume compared to those before treatment. These findings suggest that ATZ/BV treatment may increase portal pressure. In conclusion, the administration of ATZ/BV to patients with LC and u-HCC necessitates careful management of EVs aggravation and rupture.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of colon cancer implanted on endoscopic resection ulcer certified by cancer genomic testing. 一例经癌症基因组检测证实的内镜切除溃疡上的植入性结肠癌。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-09-26 DOI: 10.1007/s12328-024-02037-3

Yuji Urabe, Hidenori Tanaka, Hikaru Nakahara, Fumiaki Tanino, Ken Yamashita, Shintaro Akabane, Akira Ishikawa, Manabu Shimomura, Hideki Ohdan, Shiro Oka

{"title":"A case of colon cancer implanted on endoscopic resection ulcer certified by cancer genomic testing.","authors":"Yuji Urabe, Hidenori Tanaka, Hikaru Nakahara, Fumiaki Tanino, Ken Yamashita, Shintaro Akabane, Akira Ishikawa, Manabu Shimomura, Hideki Ohdan, Shiro Oka","doi":"10.1007/s12328-024-02037-3","DOIUrl":"10.1007/s12328-024-02037-3","url":null,"abstract":"A 90 year-old man underwent endoscopic mucosal resection for lesions in the descending and sigmoid colons as well as endoscopic submucosal dissection (ESD) for a lesion in the rectal peritoneal reflection (Ra) 1 month before undergoing laparoscopic resection and D3 dissection for advanced cancer in the descending colon. One year later, he underwent a surveillance colonoscopy, and advanced colorectal cancer was detected on the ESD scar. The history suggested that this newly detected recurrent colorectal neoplasm on the ESD scar may have originated from cancer cells derived from the descending colon cancer that were implanted in the ESD ulcer, thereby initiating a new colorectal neoplasm. Cancer genomic testing further indicated that three of the four pathogenic variants detected in the recurrent colorectal neoplasm were consistent with pathogenic variants of descending colon cancer. This finding strongly supports our contention that cancer cells derived from the descending colon cancer were implanted in the post-ESD ulcer of the rectal Ra and proliferated, forming the recurrent colorectal neoplasm. This case report highlights the potential for tumor cell implantation on endoscopic resection ulcers and the utility of cancer genomic testing in validating this phenomenon.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metastatic melanoma: an unexpected cause of acute liver failure. 转移性黑色素瘤：急性肝功能衰竭的意外病因。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-09-17 DOI: 10.1007/s12328-024-02039-1

Robert S O'Neill, Phillip Leaver, Connor Ryan, Sharron Liang, Santosh Sanagapalli, Rasha Cosman

{"title":"Metastatic melanoma: an unexpected cause of acute liver failure.","authors":"Robert S O'Neill, Phillip Leaver, Connor Ryan, Sharron Liang, Santosh Sanagapalli, Rasha Cosman","doi":"10.1007/s12328-024-02039-1","DOIUrl":"10.1007/s12328-024-02039-1","url":null,"abstract":"Acute liver failure secondary to metastatic melanoma is exceedingly rare with the literature limited to case reports. The disease itself presents with vague symptoms making diagnosis difficult without a high clinical suspicion. Further to this, the prognosis of acute liver failure secondary to metastatic melanoma is dismal. We present the case of a 59-year-old male with a distant history of previously excised cutaneous melanoma who presented to our institution with abdominal pain and liver enzyme derangement suggestive of acute hepatitis. Due to progressive derangement in liver function and cross-sectional imaging suggestive of an infiltrative cause, a left axillary lymph node was biopsied which demonstrated metastatic melanoma. The patient subsequently deteriorated into acute liver failure and despite acute treatment of his underlying metastatic melanoma died 17 days post initial presentation. This case highlights an uncommon cause of acute liver failure as well as the poor prognosis associated with acute liver failure secondary to metastatic melanoma.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse large B-cell lymphoma of the gallbladder with hepatoduodenal invasion exhibiting a necrotic tendency. 胆囊弥漫大 B 细胞淋巴瘤，伴有肝十二指肠侵犯，呈坏死倾向。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-09-10 DOI: 10.1007/s12328-024-02034-6

Hironao Matsumoto, Shunsuke Horitani, Yutaro Tokutomi, Masataka Kano, Masahiro Orino, Kanehiko Suwa, Masahiro Takeo, Toshiyuki Mitsuyama, Takeshi Yamashina, Masaaki Shimatani

{"title":"Diffuse large B-cell lymphoma of the gallbladder with hepatoduodenal invasion exhibiting a necrotic tendency.","authors":"Hironao Matsumoto, Shunsuke Horitani, Yutaro Tokutomi, Masataka Kano, Masahiro Orino, Kanehiko Suwa, Masahiro Takeo, Toshiyuki Mitsuyama, Takeshi Yamashina, Masaaki Shimatani","doi":"10.1007/s12328-024-02034-6","DOIUrl":"10.1007/s12328-024-02034-6","url":null,"abstract":"We report a case of diffuse large B-cell lymphoma (DLBCL) of the gallbladder with extensive hepatoduodenal invasion, which was challenging to diagnose histologically due to a strong tendency to be necrotic. An 71 year-old man presented with upper abdominal pain and was referred to our hospital. Computed tomography revealed a distended gallbladder with air within the irregular gallbladder wall and an indistinct border with the hepatoduodenum, suggesting invasion. Esophagogastroduodenoscopy detected an ulceration in the duodenal bulb. However, histologic analysis failed to provide a definitive diagnosis due to the presence of necrotic tissue. Furthermore, direct biopsy from the gallbladder mucosa by endoscopic retrograde cholangiography revealed only necrotic tissue and no diagnosis. Contrast ultrasonography for the hepatic invasion revealed enhancement with blood flow, suggesting non-necrotic tissue. Subsequently, an ultrasound-guided core-needle biopsy was conducted to obtain tissue samples from the described lesion. The pathology showed atypical lymphocytes with irregular nuclei. Immunostaining indicated positive expression of CD10, CD20, Bcl-6, and C-Myc, consistent with a diagnosis of DLBCL. In our case, the lymphoma exhibited a strong tendency to be necrotic, making histologic diagnosis difficult. However, selective biopsy from the site of blood flow made the diagnosis possible and proved to be useful.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Portal vein stenting blocked the inflow tract and completely resolved bile duct varices, formed by cavernous transformation of the portal vein. 门静脉支架植入术阻断了流入道，彻底消除了由门静脉海绵状变形成的胆管静脉曲张。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-08-20 DOI: 10.1007/s12328-024-02029-3

Daiyu Matsubara, Naotaka Kugiyama, Katsuya Nagaoka, Motohiro Yoshinari, Shunpei Hashigo, Keita Shimata, Yoshitaka Tamura, Toshinori Hirai, Taizo Hibi, Yasuhito Tanaka

{"title":"Portal vein stenting blocked the inflow tract and completely resolved bile duct varices, formed by cavernous transformation of the portal vein.","authors":"Daiyu Matsubara, Naotaka Kugiyama, Katsuya Nagaoka, Motohiro Yoshinari, Shunpei Hashigo, Keita Shimata, Yoshitaka Tamura, Toshinori Hirai, Taizo Hibi, Yasuhito Tanaka","doi":"10.1007/s12328-024-02029-3","DOIUrl":"10.1007/s12328-024-02029-3","url":null,"abstract":"There is no established treatment for bleeding bile duct varices (BDVs). We report the first case of portal vein (PV) stenting completely eradicating bleeding BDVs. A 70-year-old male with malignant lymphoma developed BDVs due to PV obstruction, which had caused compression and stricture of the distal bile duct. Endoscopic retrograde cholangiography was performed to evaluate the stricture and bleeding from the ruptured BDV was observed. Endoscopic hemostasis was difficult, requiring reopening of the extra-hepatic PV and reducing the blood flow to the BDVs for hemostasis. Therefore, PV stenting was performed. During the procedure, portal angiography confirmed an inflow tract to the BDVs. Therefore, covered stents were placed in the PV and adjusted to block the inflow tract to the BDVs at the distal end. After stenting, the BDVs were successfully blocked and all PV blood flowed through the stent placed in the extra-hepatic PV. Two weeks after stenting, the BDVs had disappeared completely and the bleeding has not recurred for months. We experienced a case in which PV stenting not only reopened an obstructed PV but also successfully occluded the inflow tract. This case demonstrates the potential of PV stenting for the treatment of hemorrhagic BDVs.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic ultrasound-guided drainage for mediastinal abscess: first report of bridge to surgery for esophageal cancer. 内窥镜超声引导下纵隔脓肿引流术：首次报告食管癌手术的桥梁。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-10-17 DOI: 10.1007/s12328-024-02049-z

Yoshitaro Yamamoto, Kazuo Hara, Nozomi Okuno, Nobumasa Mizuno, Shin Haba, Takamichi Kuwahara, Toshitaka Fukui, Takashi Kondo, Minako Urata

{"title":"Endoscopic ultrasound-guided drainage for mediastinal abscess: first report of bridge to surgery for esophageal cancer.","authors":"Yoshitaro Yamamoto, Kazuo Hara, Nozomi Okuno, Nobumasa Mizuno, Shin Haba, Takamichi Kuwahara, Toshitaka Fukui, Takashi Kondo, Minako Urata","doi":"10.1007/s12328-024-02049-z","DOIUrl":"10.1007/s12328-024-02049-z","url":null,"abstract":"Perforated esophageal cancer rarely results in the formation of mediastinal abscess. Endoscopic ultrasound (EUS)-guided abscess drainage (AD) has increasingly been used in the management of abscesses in locations that are difficult to treat percutaneously. We describe a case of EUS-AD for mediastinal abscess due to perforating esophageal cancer and successful bridge to surgery. A 71-year-old man with suspected esophageal issues was referred to our hospital. Computed tomography showed an esophageal cancer perforating the mediastinum, forming a mediastinal abscess. EUS-AD was planned before curative resection, because there was little improvement in inflammatory response with antimicrobial therapy. The mediastinal abscess cavity was confirmed on EUS and punctured using a 19-G needle, and then, a 0.025-inch guidewire was placed in the abscess cavity. The fistula was dilated with a 7-Fr dilator and a 6-Fr, single-pigtail nasobiliary tube was placed in the abscess cavity. One month later, clinical signs had improved and curative surgery was performed. Postoperative adjuvant therapy was administered using fluorouracil/cisplatin therapy. As of 2 years postoperatively, the patient remains free of recurrence.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Symptomatic hepatic cyst treated with endoscopic ultrasound-guided drainage and minocycline hydrochloride injection: a case report. 通过内窥镜超声引导引流和盐酸米诺环素注射治疗无症状肝囊肿：病例报告。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-08-05 DOI: 10.1007/s12328-024-02028-4

Kensuke Hoshi, Naoki Okano, Yoichiro Sato, Shuntaro Iwata, Yusuke Kimura, Susumu Iwasaki, Kensuke Takuma, Yoshinori Igarashi, Takahisa Matsuda

引用次数: 0

Abscopal effect in a patient with advanced hepatocellular carcinoma upon resuming bevacizumab in combination with atezolizumab after radiotherapy. 一名晚期肝细胞癌患者在放疗后恢复贝伐珠单抗联合阿特珠单抗治疗时的失神效应。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-08-14 DOI: 10.1007/s12328-024-02030-w

Tasuku Nakabori, Toshiki Ikawa, Kazuhiro Kozumi, Makiko Urabe, Yugo Kai, Ryoji Takada, Kenji Ikezawa, Kaori Mukai, Koji Konishi, Kazuyoshi Ohkawa

{"title":"Abscopal effect in a patient with advanced hepatocellular carcinoma upon resuming bevacizumab in combination with atezolizumab after radiotherapy.","authors":"Tasuku Nakabori, Toshiki Ikawa, Kazuhiro Kozumi, Makiko Urabe, Yugo Kai, Ryoji Takada, Kenji Ikezawa, Kaori Mukai, Koji Konishi, Kazuyoshi Ohkawa","doi":"10.1007/s12328-024-02030-w","DOIUrl":"10.1007/s12328-024-02030-w","url":null,"abstract":"Combining bevacizumab with atezolizumab enhances the antitumor effects of the treatment by activating an immune response. This combination is approved for the treatment of unresectable hepatocellular carcinoma (HCC). An abscopal effect is associated with an immune response triggered by radiation-induced immunogenic cell death, based on experimental models. Thus, combining radiotherapy and immunotherapy is expected to induce an abscopal effect. However, the clinical significance of immunotherapy in the abscopal effect remains unknown due to the rarity of clinical cases. Herein, we report a case of advanced HCC with lung and adrenal metastases. The antitumor efficacy of atezolizumab and bevacizumab (atezo/bev) was enhanced following stereotactic body radiotherapy (SBRT), although atezo/bev did not yield a sufficient therapeutic response pre-SBRT. Furthermore, an abscopal effect following SBRT was not observed during atezolizumab alone but was evoked after resuming bevacizumab in combination with atezolizumab, culminating in the patient achieving a complete response status. These findings suggest that immune activation following radiotherapy may be related to the induction of an abscopal effect in clinical practice as well as in experimental settings, and combining immunotherapy with bevacizumab post-radiotherapy could evoke an abscopal effect in a case of HCC, even though immune checkpoint inhibitor use alone may be insufficient.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful radical surgery for lymph node metastasis in a patient with hepatocellular carcinoma following atezolizumab plus bevacizumab combination therapy: a case report and literature review. 阿特珠单抗加贝伐单抗联合疗法成功为一名肝细胞癌患者实施淋巴结转移根治术：病例报告和文献综述。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-08-20 DOI: 10.1007/s12328-024-02032-8

Ken Sato, Takehiro Shimizu, Akira Watanabe, Ayako Yamazaki, Yuki Kanayama, Tatsuma Murakami, Norifumi Harimoto, Hideaki Yokoo, Ken Shirabe, Toshio Uraoka

{"title":"Successful radical surgery for lymph node metastasis in a patient with hepatocellular carcinoma following atezolizumab plus bevacizumab combination therapy: a case report and literature review.","authors":"Ken Sato, Takehiro Shimizu, Akira Watanabe, Ayako Yamazaki, Yuki Kanayama, Tatsuma Murakami, Norifumi Harimoto, Hideaki Yokoo, Ken Shirabe, Toshio Uraoka","doi":"10.1007/s12328-024-02032-8","DOIUrl":"10.1007/s12328-024-02032-8","url":null,"abstract":"A woman in her early 80 s was followed up in our hospital for chronic hepatitis C after viral eradication. We detected rapid-growing lymph node metastasis of hepatocellular carcinoma (HCC) after treatment with transcatheter arterial chemoembolization and/or radiofrequency ablation. We found that the metastasis was operable, but the size and location of the metastasis obliged the patient to receive pancreatoduodenectomy, which was too invasive. Then we initiated systemic chemotherapy to perform radical minimally invasive surgery. We treated the patient with 3 weekly cycles of atezolizumab 1200 mg plus bevacizumab 15 mg/kg. The patient tolerated the treatment well, and treatment-emergent adverse events included deterioration of hypertension and increased uric protein. After a total of 4 cycles of therapy, abdominal computed tomography findings showed that the metastasis evidently decreased, and a complete response was achieved based on the Revised Response Evaluation Criteria in Solid Tumors (RECIST) guidelines (version 1.1). Seventeen days later, the metastasis was dissected. Subsequently, we confirmed that there was no pathological metastatic lesion in the resected lymph node. Our case is the first report of successful application of the radical therapy to lymph node metastasis of HCC via combination therapy with atezolizumab/bevacizumab.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0