Clinical Journal of Gastroenterology最新文献_第2页

Difficult-to-diagnose duodenal adenocarcinoma with rare invasive form. 难以诊断的罕见侵袭性十二指肠腺癌。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-06-07 DOI: 10.1007/s12328-025-02157-4

Masatoshi Murakami, Nao Fujimori, Shoko Noguchi, Takeo Yamamoto, Kazuhide Matsumoto, Keijiro Ueda, Naoki Ikenaga, Shinichi Aishima, Masafumi Nakamura, Yoshihiro Ogawa

{"title":"Difficult-to-diagnose duodenal adenocarcinoma with rare invasive form.","authors":"Masatoshi Murakami, Nao Fujimori, Shoko Noguchi, Takeo Yamamoto, Kazuhide Matsumoto, Keijiro Ueda, Naoki Ikenaga, Shinichi Aishima, Masafumi Nakamura, Yoshihiro Ogawa","doi":"10.1007/s12328-025-02157-4","DOIUrl":"10.1007/s12328-025-02157-4","url":null,"abstract":"A 73-year-old man presented with liver dysfunction secondary to a distal bile duct stenosis. Initially, an ampullary neoplasm was suspected. Cytological and histological examinations were repeated, but no definite malignant cells were detected. The bile duct stricture improved with temporary metal stent placement. However, 21 months after the initial visit, stenosis of the second part of the duodenum was observed. Despite the absence of malignant cells, pancreaticoduodenectomy was performed due to strong suspicion of cancerous stenosis. Post-operative pathological findings revealed primary advanced duodenal carcinoma (pT4, pN1, cM0, and pStage IIIA), with the tumor extensively involving the submucosal tissue of the duodenum and extending to the muscular to the serosal layers. Invasion into the bile duct, pancreas, and ampulla or peri-ampullary duodenum was observed, but tumor cells were scattered within normal mucosa, complicating preoperative diagnosis. He received capecitabine/oxaliplatin as adjuvant chemotherapy for 6 months, and 14 months postoperatively, no recurrence was observed.This is an extremely rare case of duodenal carcinoma extending into the submucosal tissue, with no previous reports of such an extension. Bile duct strictures can be challenging to differentiate between benign and malignant causes, and duodenal carcinoma should be considered as a contributing factor.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"639-645"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous rupture of hepatocellular carcinoma in Fontan-associated liver disease with fatal outcome: case report and literature review. 方丹相关肝病肝细胞癌自发破裂致死性结局：病例报告及文献复习

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-04-27 DOI: 10.1007/s12328-025-02132-z

Taiki Okumura, Nana Yamakita, Ayumi Sugiura, Takanobu Iwadare, Hiroyuki Kobayashi, Shun-Ichi Wakabayashi, Yuki Yamashita, Hirohiko Motoki, Takefumi Kimura

{"title":"Spontaneous rupture of hepatocellular carcinoma in Fontan-associated liver disease with fatal outcome: case report and literature review.","authors":"Taiki Okumura, Nana Yamakita, Ayumi Sugiura, Takanobu Iwadare, Hiroyuki Kobayashi, Shun-Ichi Wakabayashi, Yuki Yamashita, Hirohiko Motoki, Takefumi Kimura","doi":"10.1007/s12328-025-02132-z","DOIUrl":"10.1007/s12328-025-02132-z","url":null,"abstract":"The Fontan procedure is the definitive palliative operation for patients with single-ventricle physiology. In parallel with the longer survival time achieved by the Fontan procedure, however, the incidence of Fontan-associated liver disease is increasing as well. A 25-year-old man who underwent the Fontan procedure at the age of 3 years was referred to our hospital for further evaluation of congestive hepatopathy under suspicion of Fontan-associated liver disease. Upon presentation, a heterogeneous mass of 32 × 27 mm was identified in the S4 region of the liver. The tumor showed progressive enlargement along with a rising α-fetoprotein level. We suspected hepatocellular carcinoma and scheduled a hepatectomy. On the first day of hospitalization for preoperative examination in our cardiology department, he unexpectedly suffered spontaneous hepatocellular carcinoma rupture. In spite of emergency transcatheter arterial embolization of the hepatic artery and additional interventions, the patient ultimately succumbed to intraperitoneal bleeding. Given the poor prognosis of HCC rupture in Fontan-associated liver disease, early intervention is crucial to prevent fatal outcomes.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"667-674"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of anastomotic recurrence 12 years after intersphincteric resection for anorectal malignant melanoma. 肛门直肠恶性黑色素瘤括约肌间切除术12年后吻合口复发1例。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-05-04 DOI: 10.1007/s12328-025-02140-z

Sato Nishida, Tatsuya Shonaka, Tomohiro Takeda, Masahide Otani, Mizuho Ohara, Chikayoshi Tani, Manami Hayashi, Tomoe Nakagawa, Kimiharu Hasegawa, Hideki Yokoo

{"title":"A case of anastomotic recurrence 12 years after intersphincteric resection for anorectal malignant melanoma.","authors":"Sato Nishida, Tatsuya Shonaka, Tomohiro Takeda, Masahide Otani, Mizuho Ohara, Chikayoshi Tani, Manami Hayashi, Tomoe Nakagawa, Kimiharu Hasegawa, Hideki Yokoo","doi":"10.1007/s12328-025-02140-z","DOIUrl":"10.1007/s12328-025-02140-z","url":null,"abstract":"Anorectal malignant melanoma (AMM) is a rare disease with a poor prognosis, accounting for < 1.0% of all malignant melanomas and a 5-year survival rate of 19.2%. The treatment is mainly surgical, and lymph-node dissection is often performed. Cases of recurrence after a prolonged period (> 10 years), as in the present case, are rare. The patient was an 80-year-old woman who underwent laparoscopic intersphincteric resection with bilateral lateral lymph-node dissection for the diagnosis of primary AMM of the lower rectum at X - 12 years. The pathology was pStage III and the resection margins were negative. Twelve years after the initial surgery, in year X, the patient visited our hospital with the chief complaint of discomfort due to a tumor in the anorectal region. Biopsy revealed a recurrence, and laparoscopic abdominoperineal resection was performed. Based on the pathological findings, the patient was diagnosed with local recurrence of the anastomotic anal canal. Both the first and second specimens were negative for BRAF V600E/K mutation. Four months have passed since the surgery, and the patient continued to receive nivolumab without recurrence. Long-term local follow-up is necessary when the anal canal is preserved during AMM surgery.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"581-587"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term survival after chemotherapy combined immunotherapy for recurrent mixed neuroendocrine-non-neuroendocrine neoplasms of the common bile duct. 化疗联合免疫治疗复发性胆总管混合性神经内分泌-非神经内分泌肿瘤的远期生存率。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-04-17 DOI: 10.1007/s12328-025-02128-9

Jia Li, Chunyan Yuan, Yulin Pan, Yuanyuan Yang, Nannan Lai, Xia Sheng

{"title":"Long-term survival after chemotherapy combined immunotherapy for recurrent mixed neuroendocrine-non-neuroendocrine neoplasms of the common bile duct.","authors":"Jia Li, Chunyan Yuan, Yulin Pan, Yuanyuan Yang, Nannan Lai, Xia Sheng","doi":"10.1007/s12328-025-02128-9","DOIUrl":"10.1007/s12328-025-02128-9","url":null,"abstract":"Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) of the common bile duct (CBD) are extremely rare, with few literature reported. A 68-year-old male was admitted to our hospital with choledocholithiasis with acute cholangitis. Abdominal computed tomography showed that the CBD was occupied and clearly dilated. Consequently, the patient underwent pancreaticoduodenectomy with regional lymph node dissection. The resected tumor at the distal bile duct was 25 × 25 × 13 mm, consisting of 30% adenocarcinoma and 70% neuroendocrine carcinoma microscopically. The patient then received six cycles of adjuvant chemotherapy. Subsequently, regular monitoring of the patient's tumor marker CA19-9 showed progressive elevation. The patient was readmitted to hospital for tumor recurrence and metastasis and received palliative second-line Gemcitabine and cisplatin chemotherapy and three courses of combined immunochemotherapy (Tyvyt [Sintilimab] + Gemcitabine + Cisplatin). Throughout the treatment course, the tumor marker CA19-9 persistently remained elevated. The patient achieved an overall survival (OS) of 29 months. We found that the continuous elevation of the tumor marker CA19-9 during follow-up might suggest tumor recurrence and an unfavorable prognosis. For patients with multiple metastases of cholangiocarcinoma, combined immunotherapy could potentially assist in prolonging survival. Currently, there is no standardized treatment for biliary MiNENs, and larger scale studies are needed to establish diagnosis and treatment protocols to improve the overall survival of patients.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"653-659"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term survival with complete remission after irinotecan plus cisplatin therapy for metachronous liver metastasis from a gastric mixed neuroendocrine-non-neuroendocrine neoplasm: a case report. 伊立替康加顺铂治疗胃混合性神经内分泌-非神经内分泌肿瘤异时性肝转移后的长期完全缓解1例。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-05-01 DOI: 10.1007/s12328-025-02139-6

Kazuhiro Yasuda, Shoichi Inokuchi, Satoshi Tsutsumi, Hiroomi Takayama, Masahiko Ikebe, Toshio Bandou, Tohru Utsunomiya, Shogo Urabe

{"title":"Long-term survival with complete remission after irinotecan plus cisplatin therapy for metachronous liver metastasis from a gastric mixed neuroendocrine-non-neuroendocrine neoplasm: a case report.","authors":"Kazuhiro Yasuda, Shoichi Inokuchi, Satoshi Tsutsumi, Hiroomi Takayama, Masahiko Ikebe, Toshio Bandou, Tohru Utsunomiya, Shogo Urabe","doi":"10.1007/s12328-025-02139-6","DOIUrl":"10.1007/s12328-025-02139-6","url":null,"abstract":"Gastric mixed neuroendocrine-non-neuroendocrine neoplasm, which consists of both exocrine and endocrine components, is rare and exhibits aggressive biological behavior and poor prognosis. A 64-year-old man underwent investigation for abdominal pain. An endoscopic examination revealed a 30-mm protruded lesion in the gastric antrum for which distal gastrectomy with lymph node dissection was performed. Histopathological examination showed two distinct components, an adenocarcinoma component and neuroendocrine carcinoma component, with immunohistochemical staining positive for CD56, chromogranin A, and synaptophysin. The final diagnosis was mixed neuroendocrine-non-neuroendocrine neoplasm, pT2, pN3, M0, stage IIIA. Multiple liver metastases were detected 3 months after surgery. The patient received irinotecan plus cisplatin therapy, which was effective, and the liver metastases disappeared. The patient remains alive, without any recurrence, more than 10 years after surgery. We present a rare case of gastric mixed neuroendocrine-non-neuroendocrine neoplasm and review the literature to contribute to improving our understanding of this kind of tumor.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"573-580"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraduodenal wall recurrence 11 years after distal pancreatectomy for pancreatic ductal adenocarcinoma. 胰管腺癌远端胰腺切除术后11年的十二指肠内壁复发。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-05-16 DOI: 10.1007/s12328-025-02141-y

Mikkaichi Ko, Junichi Kaneko, Rika Fujino, Hisamichi Yoshii, Hideki Izumi, Tomoko Sugiyama, Takuma Tajiri, Tomoko Hanashi, Masaya Mukai, Hiroyasu Makuuchi

引用次数: 0

Carcinoma in situ of the pancreas detected by progressive focal pancreatic parenchymal atrophy without main pancreatic ductal change. 胰腺原位癌通过进展性局灶性胰腺实质萎缩而未见主要胰管改变。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-06-09 DOI: 10.1007/s12328-025-02158-3

Shigeru Nishiyama, Takeshi Hisa, Shogo Sakata, Yui Ito, Akiharu Kudo, Takahiro Yamada, Shozo Osera, Hideki Fukushima, Ryoga Hamura, Satoshi Shiozawa

{"title":"Carcinoma in situ of the pancreas detected by progressive focal pancreatic parenchymal atrophy without main pancreatic ductal change.","authors":"Shigeru Nishiyama, Takeshi Hisa, Shogo Sakata, Yui Ito, Akiharu Kudo, Takahiro Yamada, Shozo Osera, Hideki Fukushima, Ryoga Hamura, Satoshi Shiozawa","doi":"10.1007/s12328-025-02158-3","DOIUrl":"10.1007/s12328-025-02158-3","url":null,"abstract":"We report a case in which the progression of focal pancreatic parenchymal atrophy suggested the presence of high-grade pancreatic intraepithelial neoplasia/carcinoma in situ. A 77-year-old man was found to have a pancreatic cyst during a health checkup using transabdominal ultrasound. Contrast-enhanced computed tomography revealed multiple cysts, each measuring ≤ 5 mm, in the pancreatic head and body. Over nine years of intermittent follow-up, imaging showed progressive focal pancreatic parenchymal atrophy extending from the pancreatic head to the body, without changes in the cysts or stenosis or dilatation of the main pancreatic duct. Three-dimensional computed tomography facilitated visualization of the atrophic progression. Transabdominal and endoscopic ultrasound identified a thin pancreatic parenchyma with a surrounding hyperechoic area but no hypoechoic masses. Serial pancreatic juice aspiration cytological examination suggested adenocarcinoma. Surgery was performed, and histopathological examination revealed a 15-mm atrophic region with high-grade pancreatic intraepithelial neoplasia or carcinoma in situ confined to the main pancreatic duct. The lesion extended 5 mm downstream and 10 mm upstream. Even in cases of focal pancreatic parenchymal atrophy without stenosis or dilation of the main pancreatic duct, its progression may indicate high-grade pancreatic intraepithelial neoplasia/carcinoma in situ and warrant serial pancreatic juice aspiration cytology.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"746-752"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IgG4-AIH with multiple inflammatory pseudotumors and decreased OATP1B3 expression. IgG4-AIH伴多发炎性假瘤，OATP1B3表达降低。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-06-17 DOI: 10.1007/s12328-025-02161-8

Ryusuke Hanafusa, Kazuto Tajiri, Nozomu Muraishi, Kenichi Hirabayashi, Koichi Tsuneyama, Ichiro Yasuda

引用次数: 0

A case of Budd-Chiari syndrome with acute venous thrombosis and liver failure: highlighting the importance of early intervention and anticoagulation therapy. Budd-Chiari综合征合并急性静脉血栓和肝功能衰竭1例：强调早期干预和抗凝治疗的重要性。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-04-24 DOI: 10.1007/s12328-025-02135-w

Yumi Otoyama, Masamichi Kimura, Koji Nishikawa, Jun Imamura, Kiminori Kimura

{"title":"A case of Budd-Chiari syndrome with acute venous thrombosis and liver failure: highlighting the importance of early intervention and anticoagulation therapy.","authors":"Yumi Otoyama, Masamichi Kimura, Koji Nishikawa, Jun Imamura, Kiminori Kimura","doi":"10.1007/s12328-025-02135-w","DOIUrl":"10.1007/s12328-025-02135-w","url":null,"abstract":"Budd-Chiari syndrome is a rare and potentially fatal disorder characterized by obstruction or narrowing of the hepatic veins and inferior vena cava. The acute form of the disease often leads to rapid liver failure. In Asia, membranous obstruction of the hepatic portion of the inferior vena cava and localized stenosis at the hepatic venous origin are more common, while in Western countries, hepatic vein obstruction due to underlying thrombotic conditions is more prevalent. Treatment strategies vary and depend on disease severity and location. Anticoagulation therapy is the standard treatment in Western countries but is less commonly used in Japan where catheter-based interventions, such as recanalization, balloon dilation, and stenting, are more frequently employed. We report the case of a 51-year-old man diagnosed with Budd-Chiari syndrome after the treatment of esophageal varices. He initially responded well to nafamostat and balloon dilation, maintaining stability for 8 years, but later developed acute complications, including venous thrombosis and liver failure, despite previously stable follow-up. The patient succumbed to his condition despite aggressive treatment, highlighting the importance of early detection and intervention. This case underscores the need for clearer guidelines on anticoagulation therapy in Japan and emphasizes early management to improve prognosis.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"689-694"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ascending colon cancer with spontaneous regression of the primary tumor despite persistent isolated regional lymph node metastasis. 升格结肠癌，原发肿瘤自发消退，尽管持续孤立的区域淋巴结转移。

IF 0.9

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-05-14 DOI: 10.1007/s12328-025-02143-w

Yu Watahiki, Kazumasa Kawashima, Michio Onizawa, Daiki Nemoto, Takuro Matsumoto, Wataru Sakamoto, Rei Sekine, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira

{"title":"Ascending colon cancer with spontaneous regression of the primary tumor despite persistent isolated regional lymph node metastasis.","authors":"Yu Watahiki, Kazumasa Kawashima, Michio Onizawa, Daiki Nemoto, Takuro Matsumoto, Wataru Sakamoto, Rei Sekine, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira","doi":"10.1007/s12328-025-02143-w","DOIUrl":"10.1007/s12328-025-02143-w","url":null,"abstract":"Spontaneous regression of cancer, particularly that of colorectal cancer, is rare. We encountered a rare case of spontaneous regression of ascending colon cancer with regional lymph node metastasis. A 70-year-old woman was referred for colonoscopy after a fecal immunochemical test yielded positive results. A colonoscopy revealed a 15-mm depressed lesion that was confirmed as adenocarcinoma. Regression of the primary tumor was observed over the course of multiple endoscopic examinations. Subsequently, robot-assisted laparoscopic right hemicolectomy and D3 lymph node dissection were performed. A histopathological examination revealed complete regression of the primary tumor. However, metastasis to a regional lymph node was observed. Immunohistochemistry indicated colon cancer with high microsatellite instability, infiltration of CD4-positive T cells, and predominant infiltration of CD8-positive T cells at the primary site and metastatic lymph node. Immunological studies of the regressed primary tumor and remaining lymph node metastasis instigated a discussion regarding spontaneous regression mechanisms. This case emphasizes the necessity for vigilant clinical management of similar cases because the potential for lymph node metastasis persists even when the spontaneous regression of the primary tumor is observed.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"588-594"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0