{"title":"Over-the-scope clip closure for penetrating duodenal injury after cryotherapy for renal cell carcinoma.","authors":"Taku Kano, Naoto Iwai, Osamu Dohi, Hayato Fukui, Ryohei Obata, Tomoki Uehara, Junki Yumoto, Hiroki Mukai, Tomoko Ochiai, Hideyuki Konishi","doi":"10.1007/s12328-026-02348-7","DOIUrl":"https://doi.org/10.1007/s12328-026-02348-7","url":null,"abstract":"<p><p>Gastrointestinal injury is a rare complication of renal cryoablation. In this report, we present a case of penetrating duodenal injury following renal cryoablation that was successfully managed with over-the-scope clip closure. A 92-year-old male patient was referred to our hospital after sustaining a penetrating duodenal injury caused by percutaneous cryotherapy for renal cell carcinoma. The patient had undergone computed tomography-guided percutaneous cryotherapy for right renal cell carcinoma 1 month previously. Follow-up computed tomography suggested a duodenal injury, although no abdominal symptoms were evident. Esophagogastroduodenoscopy revealed a full-thickness duodenal defect. He underwent endoscopic suturing for the duodenal injury using an over-the-scope clip system. The patient's clinical course following treatment was uneventful. Gastrointestinal injury can be a rare complication of cryotherapy for renal cell carcinoma, and this case suggests the potential utility of the over-the-scope clip system for the complete closure of a penetrating duodenal injury after renal cryoablation.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lymph node metastatic recurrence detected by an increased serum carcinoembryonic antigen concentration after endoscopic submucosal dissection for esophageal cancer with invasion to the lamina propria mucosae.","authors":"Hisaki Doyama, Hiroyoshi Nakanishi, Yuta Yatsuo, Yuki Kaneko, Yosuke Kito, Kunihiro Tsuji, Kazuyoshi Katayanagi, Hiroshi Minato, Hisashi Doyama, Shigetsugu Tsuji","doi":"10.1007/s12328-026-02349-6","DOIUrl":"https://doi.org/10.1007/s12328-026-02349-6","url":null,"abstract":"<p><p>A 64-year-old man underwent endoscopic submucosal dissection (ESD) for squamous cell carcinoma in the upper thoracic esophagus. The resected specimen was histopathologically diagnosed as esophageal squamous cell carcinoma with pathological invasion to the T1a-lamina propria mucosae without lymphovascular invasion and was determined to have been curatively resected. Twenty-six months after ESD, the patient had an increased serum carcinoembryonic antigen (CEA) concentration of 14.0 ng/mL. Comprehensive examination revealed multiple lymphadenopathies. A biopsy of the right supraclavicular lymph node confirmed metastasis of squamous cell carcinoma. Immunohistochemical study for CEA was focally positive in the primary ESD specimen, whereas nearly all tumor cells in the metastatic lesion were positive. Therefore, it was considered that the metastatic lesion originated from the CEA-positive subpopulation of the primary tumor. This is the first case of lymph node metastatic recurrence detected based on an increased serum CEA concentration after ESD for esophageal squamous cell carcinoma with invasion to the T1a-lamina propria mucosae. Serum CEA measurement was useful for detecting the recurrence. Furthermore, this case suggests that CEA immunohistochemical study may be useful for the assessment of metastatic risk following curative ESD for esophageal squamous cell carcinoma.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of gastric sinus abscess, a rare disease successfully treated by endoscopic incision and drainage.","authors":"Weijing Wang, Teng Wang, Duo Wei, Rong Zhang","doi":"10.1007/s12328-026-02345-w","DOIUrl":"https://doi.org/10.1007/s12328-026-02345-w","url":null,"abstract":"","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidental intrahepatic cholangiocarcinoma detected in the explant liver after living-donor liver transplantation for polycystic liver disease.","authors":"Satoshi Asanuma, Koichiro Haruki, Kenei Furukawa, Shinji Onda, Yoshihiro Shirai, Michinori Matsumoto, Tomohiko Taniai, Masashi Tsunematsu, Mitsuru Yanagaki, Toru Ikegami","doi":"10.1007/s12328-026-02343-y","DOIUrl":"https://doi.org/10.1007/s12328-026-02343-y","url":null,"abstract":"<p><p>Living-donor liver transplantation (LDLT) is considered for polycystic liver disease (PLD) with portal hypertension or quality of life deterioration. However, concomitant malignant tumors are extremely rare in PLD. The recipient was a 68-year-old female who had been followed for PLD. She developed progressive jaundice with ascites and lower leg edema. Computed tomography revealed portal hypertension with intrahepatic portal vein stenosis and splenorenal shunt. The liver was replaced by numerous cysts, but no obvious tumorous lesions were identified. Tumor markers were CEA of 7.9 ng/ml and CA19-9 of 420 U/ml. With a MELD score of 12 and Child-Pugh grade C, LDLT was planned. The living liver donor was her 42-year-old daughter, and a right lobe graft was planned for the transplantation with predicted graft-to-recipient weight ratio (GRWR) of 0.88. Portal inflow modulation was performed with proximal splenic artery embolization before LDLT. The operation time was 351 min and the intraoperative blood loss was 2,100 ml. The recipient was discharged on postoperative day 17 without any complications. Although no macroscopic tumor was observed in the explanted liver, histopathological examination revealed adenocarcinoma with papillary proliferation in the cyst wall containing hematoma. Biliary intraepithelial neoplasia (BilIN-1) was also found in the adjacent cysts. The recipient remains well without recurrence with good graft function at 2.5 years after LDLT. We herein report an extremely rare case of incidental intrahepatic cholangiocarcinoma detected in the explanted liver after LDLT for PLD. The possibility of concomitant malignant tumor should be considered even in PLD.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}