Clinical Journal of Gastroenterology最新文献

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Hemorrhagic shock from gastric pseudoaneurysm post-percutaneous endoscopic gastrostomy: a case report. 经皮内镜胃造口术后胃假性动脉瘤引起的失血性休克:病例报告。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-13 DOI: 10.1007/s12328-024-02016-8
Tsutomu Nishida, Yu Higaki, Dai Nakamatsu, Kengo Matsumoto, Masashi Yamamoto
{"title":"Hemorrhagic shock from gastric pseudoaneurysm post-percutaneous endoscopic gastrostomy: a case report.","authors":"Tsutomu Nishida, Yu Higaki, Dai Nakamatsu, Kengo Matsumoto, Masashi Yamamoto","doi":"10.1007/s12328-024-02016-8","DOIUrl":"10.1007/s12328-024-02016-8","url":null,"abstract":"<p><p>Percutaneous endoscopic gastrostomy (PEG) is widely used for long-term enteral nutrition in patients unable to maintain adequate oral intake. Despite advancements in PEG techniques, complications remain a concern. We report a case of a 94-year-old bedridden man who developed significant complications after PEG placement using the pull method. Initially, minor bleeding at the puncture site was managed using traction compression. However, the patient later experienced hemorrhagic shock owing to pulsatile bleeding around the gastrostomy site. Despite attempts to control the bleeding through traction and transfusions, a pseudoaneurysm adjacent to the PEG button was identified. The patient underwent successful transcatheter arterial embolization (TAE). Post-TAE, no further bleeding or hematoma was observed, and imaging confirmed the resolution of the pseudoaneurysm and hematoma. Methicillin-resistant Staphylococcus aureus (MRSA) infection was detected at the gastrostomy site, which contributed to complications. Despite successful management of the bleeding, the patient's overall condition deteriorated, and he died on postoperative day 66. This case underscores the importance of vigilant monitoring and management of PEG-related complications, particularly infections that may precipitate severe vascular events.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"828-833"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141598783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastric band removal: mind the arterial anastomoses! 胃束带切除:注意动脉吻合!
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-15 DOI: 10.1007/s12328-024-02018-6
Gianluigi Orgera, Nicolò Ubaldi, Tommaso Rossi, Michele Rossi, Miltiadis Krokidis
{"title":"Gastric band removal: mind the arterial anastomoses!","authors":"Gianluigi Orgera, Nicolò Ubaldi, Tommaso Rossi, Michele Rossi, Miltiadis Krokidis","doi":"10.1007/s12328-024-02018-6","DOIUrl":"10.1007/s12328-024-02018-6","url":null,"abstract":"<p><p>Bariatric surgery may sometimes be challenging and may lead to severe complications. Surgical re-intervention in such cases is not the preferred option due to co-morbidities. When severe bleeding occurs, embolization of the lacerated vessels is the preferred minimal invasive management option and needs to be available if possible. We would like to report a case of young patient who underwent severe bleeding after migration of a gastric band. The patient was successfully embolized and the band was removed. However, on the second post-operative day, the patient complained again for acute abdominal pain and turned haemodynamically unstable. Fresh blood was aspirated from the surgical drain. A new emergency CT scan was performed and a new large pseudoaneurysm was revealed taking origin from the left gastric artery. The second bleeding occurred due to an anastomotic communication and was also successfully embolized. The main take home messages are that bariatric surgery may lead to several complications including bleeding, gastric band may cause vessel erosion but also offer a tamponade effect, endovascular embolization of the lacerated vessels is the preferred management and pseudoaneurysms arising in hepato-splenic or gastroduodenal arteries should be treated with the sandwich embolization technique.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"834-838"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of hemorrhagic Meckel's diverticulum diagnosed by transabdominal ultrasound. 一例经腹部超声诊断的出血性梅克尔憩室。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI: 10.1007/s12328-024-02019-5
Takako Konishi, Noriaki Manabe, Ken Haruma, Hideyo Fujiwara, Hiroyasu Fujiwara, Munenori Takaoka, Takashi Akiyama, Katsuya Kato, Jiro Hata, Tomoki Yamatsuji
{"title":"A case of hemorrhagic Meckel's diverticulum diagnosed by transabdominal ultrasound.","authors":"Takako Konishi, Noriaki Manabe, Ken Haruma, Hideyo Fujiwara, Hiroyasu Fujiwara, Munenori Takaoka, Takashi Akiyama, Katsuya Kato, Jiro Hata, Tomoki Yamatsuji","doi":"10.1007/s12328-024-02019-5","DOIUrl":"10.1007/s12328-024-02019-5","url":null,"abstract":"<p><p>A 23-year-old man with a history of anemia of unknown cause was referred to our hospital. He had experienced melena three times: at 6 months, 10 years, and 20 years of age. He underwent upper and lower gastrointestinal endoscopy at 10 and 20 years of age, and small intestinal capsule endoscopy twice at 20 years of age, but the site of bleeding could not be identified. At first, a transabdominal ultrasound was performed for suspected Meckel's diverticulum. A cystic diverticulum was found in the ileum, with an apertural diameter of 5 mm and a total size of 4 cm. The cyst showed an area of loss of wall stratification, which appeared to be an ulcer scar. Based on these observations, we diagnosed anemia resulting from a hemorrhagic Meckel's diverticulum and performed laparoscopic resection. Postoperative histopathology revealed ectopic gastric mucosa and ulcer formation within the Meckel's diverticulum, which was thought to be the cause of the bleeding. Meckel's diverticulum should be considered in cases of hemorrhage in young patients. A transabdominal ultrasound as a screening test detected a diverticulum with an ulcer scar in the ileum, which led to the identification of the underlying disease.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"876-882"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of delayed necrosis of reconstructed colon after esophagectomy. 一例食管切除术后重建结肠延迟坏死的病例。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-06-25 DOI: 10.1007/s12328-024-02009-7
Keiichiro Yokota, Hiroyuki Kitagawa, Tsutomu Namikawa, Masato Utsunomiya, Satoru Seo
{"title":"A case of delayed necrosis of reconstructed colon after esophagectomy.","authors":"Keiichiro Yokota, Hiroyuki Kitagawa, Tsutomu Namikawa, Masato Utsunomiya, Satoru Seo","doi":"10.1007/s12328-024-02009-7","DOIUrl":"10.1007/s12328-024-02009-7","url":null,"abstract":"<p><p>We report a very rare case of delayed necrosis of the reconstructed colon 6 months after esophagectomy.A 67-year-old male patient had undergone esophagectomy with gastric tube reconstruction for esophageal cancer in 2014. Subsequently, total gastrectomy and ileo-colon reconstruction via a retrosternal route was performed for gastric tube cancer in 2022. Six months later, he suffered acute chest pain and came to our hospital. Contrast-enhanced CT showed severe dilation of the reconstructed colon with poor enhancement of the wall opposite mesentery, without arterial obstruction. Endoscopy showed no ischemic changes in the esophago-ileum anastomosis; however, mucosal color change to black was observed in the reconstructed colon. We diagnosed ischemic colitis of the reconstructed colon and started conservative treatment; however, 18 days later, he developed a right pyothorax due to perforation of the reconstructed colon. We performed necrosed colectomy with right chest drainage and cervical esophageal fistula was made. Histopathological examination revealed mucosal detachment, thinning of the muscularis propria, and ghost-like appearance of crypt. If necrosis of the reconstructed colon is suspected in the late postoperative period, endoscopic findings of the colonic mucosa may be useful in determining surgical treatment, even in the absence of arterial blood flow obstruction.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"799-802"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141449874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary adenocarcinoma arising from rectal implantation cyst after low anterior resection for rectal cancer 31 years previously. 31 年前因直肠癌进行低位前切除术后,直肠种植囊肿引发的原发性腺癌。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-06-10 DOI: 10.1007/s12328-024-02002-0
Yoshifumi Shimada, Akio Matsumoto, Kaoru Abe, Yosuke Tajima, Mae Nakano, Takashi Ariizumi, Hiroyuki Kawashima, Yusuke Tani, Riuko Ohashi, Toshifumi Wakai
{"title":"Primary adenocarcinoma arising from rectal implantation cyst after low anterior resection for rectal cancer 31 years previously.","authors":"Yoshifumi Shimada, Akio Matsumoto, Kaoru Abe, Yosuke Tajima, Mae Nakano, Takashi Ariizumi, Hiroyuki Kawashima, Yusuke Tani, Riuko Ohashi, Toshifumi Wakai","doi":"10.1007/s12328-024-02002-0","DOIUrl":"10.1007/s12328-024-02002-0","url":null,"abstract":"<p><p>Rectal implantation cysts can occur at anastomotic sites after low anterior resection (LAR) for rectal cancer. Herein, we report a case of primary adenocarcinoma arising from a rectal implantation cyst after LAR for rectal cancer. A 70-year-old woman was referred to our hospital for diagnosis and treatment of a growing cystic lesion. She had LAR performed for rectal cancer 29 years previously and had a rectal implantation cyst detected 13 years previously. On the first visit to our hospital, serum CEA and CA19-9 levels were elevated, and computed tomography (CT) scans revealed a cystic lesion near the anastomosis. CT-guided biopsy revealed no cancer tissue in the cystic lesion. After that, the cystic lesion naturally shrank, and serum CEA and CA19-9 levels became normal. Follow-up included 3 monthly serum CEA and CA19-9 testing and 6 monthly CT scans. Two years later, serum CEA and CA19-9 levels were elevated again. Colonoscopy revealed an ulcerative lesion at the anastomotic site, in which adenocarcinoma was confirmed. Abdominoperineal resection with sacral resection was performed, and postoperative histopathological examination revealed a primary adenocarcinoma with mucinous component at the implantation cyst. Since rectal implantation cysts can become malignant after extended periods, clinicians need to be aware of this disease.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"899-903"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serial change in gastric motility in eosinophilic gastritis with pyloric stenosis assessment by abdominal ultrasonography. 通过腹部超声波检查评估嗜酸性粒细胞胃炎伴幽门狭窄患者胃蠕动的连续变化
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-06-10 DOI: 10.1007/s12328-024-01998-9
Hiroshi Matsumoto, Hiroaki Kusunoki, Takashi Akiyama, Keisuke Honda, Kazuma Kawahito, Momoyo Sasahira, Shogen Yo, Hiraku Misawa, Masanori Matsumoto, Akiko Shiotani
{"title":"Serial change in gastric motility in eosinophilic gastritis with pyloric stenosis assessment by abdominal ultrasonography.","authors":"Hiroshi Matsumoto, Hiroaki Kusunoki, Takashi Akiyama, Keisuke Honda, Kazuma Kawahito, Momoyo Sasahira, Shogen Yo, Hiraku Misawa, Masanori Matsumoto, Akiko Shiotani","doi":"10.1007/s12328-024-01998-9","DOIUrl":"10.1007/s12328-024-01998-9","url":null,"abstract":"<p><p>Eosinophilic gastritis (EoG) is defined as the presence of upper gastrointestinal symptoms combined with histologic findings of > 30 eosinophils/high-power field (eos/hpf) in 5 hpf in any part of the gastric mucosa, except for the secondary causes of gastric eosinophilia. This is the first case report of a serial change in gastric motility in EoG with pyloric stenosis using abdominal ultrasonography. A 56-year-old woman was diagnosed with pyloric stenosis by upper gastrointestinal radiographic examination during a medical checkup. She had nausea and loss of appetite, her gastrointestinal symptom rating scale (GSRS) score was 20, and her F scale score was 20. Esophagogastroduodenoscopy (EGD) demonstrated pyloric stenosis and multiple superficial ulcerations in the antrum. Histopathological findings of gastric biopsy specimens revealed severe eosinophilic infiltration (100 eos/HPF), and the diagnosis was EoG with pyloric stenosis. Before treatment, the gastric anterior wall thickness was 6.3 mm. The gastric motility in EoG was evaluated by intra-abdominal ultrasonography. Ultrasonography showed low motility in the antrum, especially the amplitude and motility index. After 6 months of steroid treatment, her symptoms improved. Her GSRS score was 13, and her F scale score was 19. Histological eosinophilic infiltration decreased to 50 eos/HPF, showing improvement. On ultrasonography, gastric motility also improved and recovered to normal. After 12 months, several examinations confirmed improvement, including gastric motility by ultrasonography.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"809-813"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transmesenteric internal hernia: an unexpected adverse event induced by colonoscopy. 经肠管内疝:结肠镜检查引发的意外不良事件。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-03 DOI: 10.1007/s12328-024-02013-x
Ikue Sekai, Kosuke Minaga, Akane Hara, Yasuo Otsuka, Yasuhiro Masuta, Hironori Shigeoka, Tomohiro Watanabe, Masatoshi Kudo
{"title":"Transmesenteric internal hernia: an unexpected adverse event induced by colonoscopy.","authors":"Ikue Sekai, Kosuke Minaga, Akane Hara, Yasuo Otsuka, Yasuhiro Masuta, Hironori Shigeoka, Tomohiro Watanabe, Masatoshi Kudo","doi":"10.1007/s12328-024-02013-x","DOIUrl":"10.1007/s12328-024-02013-x","url":null,"abstract":"<p><p>Transmesenteric internal hernia is an uncommon cause of small bowel obstruction that occurs when small bowel loops protrude through a mesenteric defect into the abdominal cavity. Herein, we present an unexpected case of colonoscopy-induced transmesenteric internal hernia. An 81-year-old male patient presenting with intermittent hematochezia and constipation had undergone a laparoscopic left nephrectomy for ureteral cancer. A colonoscopy was performed to identify the etiology of his symptoms. He complained of severe abdominal pain 2 h after the examination despite uneventful endoscopic procedures, including cold snare polypectomy. Contrast-enhanced computed tomography revealed a strangulated small bowel obstruction with a closed-loop formation outside the descending colon. The small bowel loop was incarcerated into the left retroperitoneal space. Emergency laparotomy detected small bowel loops that prolapsed into the nephrectomy pedicle via a descending mesenteric defect, developed during the laparoscopic left nephrectomy. The incarcerated small bowel was detached from the hernia and returned to its normal position, and the mesenteric defect was closed. He demonstrated an uneventful postoperative course, with no internal hernia recurrence after discharge. This case indicates the risk of transmesenteric internal hernia through inadvertently created mesenteric defects should be borne in mind, especially when performing colonoscopies in patients who underwent laparoscopic nephrectomies.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"861-865"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141497300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concurrent occurrence of ulcerative duodenitis and ulcerative colitis displaying unique responses to golimumab and ustekinumab. 同时发生的溃疡性十二指肠炎和溃疡性结肠炎对戈利木单抗和乌司他单抗显示出独特的反应。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-18 DOI: 10.1007/s12328-024-02012-y
Sho Masaki, Hajime Honjo, Masayuki Kurimoto, Natsuki Okai, Yasuo Otsuka, Yasuhiro Masuta, Ken Kamata, Kosuke Minaga, Masatoshi Kudo, Tomohiro Watanabe
{"title":"Concurrent occurrence of ulcerative duodenitis and ulcerative colitis displaying unique responses to golimumab and ustekinumab.","authors":"Sho Masaki, Hajime Honjo, Masayuki Kurimoto, Natsuki Okai, Yasuo Otsuka, Yasuhiro Masuta, Ken Kamata, Kosuke Minaga, Masatoshi Kudo, Tomohiro Watanabe","doi":"10.1007/s12328-024-02012-y","DOIUrl":"10.1007/s12328-024-02012-y","url":null,"abstract":"<p><p>Recent studies have reported the occurrence of upper gastrointestinal (UGI) inflammation in patients with ulcerative colitis (UC). However, whether UC-associated UGI and colorectal lesions share pathogenic cytokine profiles and responses to biologics remains unknown. Herein, we report a case of concurrent UC and ulcerative duodenitis (UD) that displayed unique responses to biologic treatment. Although treatment with prednisolone (PSL) failed to induce remission in both disorders, golimumab (GLM) and ustekinumab (UST) were effective against UD and UC, respectively, and remission of both disorders was achieved using UST. Immunofluorescence analyses revealed that numbers of immune cells expressing TNF-α were comparable in both duodenal and rectal mucosa before the treatment. GLM or UST treatment markedly decreased numbers of TNF-α-expressing duodenal immune cells, suggesting the presence of correlation between TNF-α expression and disease activity of UD. In contrast, TNF-α expression was not parallel to disease activity of UC because GLM or PSL failed to induce remission despite a marked reduction in TNF-α expression. Responsiveness to GLM or UST together with immunofluorescence studies suggests that TNF-α and IL-12/23p40 are pathogenic cytokines causing UD and UC, respectively, in the present case.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"854-860"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The usefulness of gel immersion endoscopy in identifying herald bleeding from an infectious aortoenteric fistula: a case report. 凝胶浸泡内窥镜在识别感染性肠主动脉瘘预兆出血中的作用:病例报告。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-23 DOI: 10.1007/s12328-024-02020-y
Suguo Suzuki, Masahiro Saito, Kaname Uno, Naoki Asano, Tomoyuki Koike, Daijirou Akamatsu, Masamichi Mizuma, Takashi Kamei, Michiaki Unno, Atsushi Masamune
{"title":"The usefulness of gel immersion endoscopy in identifying herald bleeding from an infectious aortoenteric fistula: a case report.","authors":"Suguo Suzuki, Masahiro Saito, Kaname Uno, Naoki Asano, Tomoyuki Koike, Daijirou Akamatsu, Masamichi Mizuma, Takashi Kamei, Michiaki Unno, Atsushi Masamune","doi":"10.1007/s12328-024-02020-y","DOIUrl":"10.1007/s12328-024-02020-y","url":null,"abstract":"<p><p>A 62-year-old male with a history of stent graft replacement for an infectious aortic aneurysm, followed by multiple interventions for postoperative complications, was admitted with melena and anemia. Enhanced computed tomography (eCT) demonstrated fluffing and hyperdensities surrounding the graft, despite no evidence of an aortoenteric fistula (AEF). Emergency esophagogastroduodenoscopy (EGD) showed a massive bleeding in the reconstructed tract and the protruding lesion of postoperative granulation tissue with clots at the end of the blind pouch. Thereafter, hemorrhage temporarily reoccurred several times; however, the source could not be identified using eCT or EGD. Finally, on the third attempt, we performed gel immersion endoscopy (GIE) with manual injection of VISCOCLEAR<sup>Ⓡ</sup>, and it showed purulent blood flowing from one side of the protruding lesion in the pouch. Based on the eCT findings showing exudation of the contrast agent from the graft into the pouch, we made a diagnosis of an AEF. However, radical surgery was not performed because of the patient's poor general condition. During conservative management, he died of uncontrolled bleeding from the AEF on the 5th day of hospitalization. This is the first case in which the GIE might provide tips to identify herald bleeding from a lethal AEF.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"871-875"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biologic therapy for ulcerative colitis associated with immune thrombocytopenia. 溃疡性结肠炎伴免疫性血小板减少症的生物疗法。
IF 0.8
Clinical Journal of Gastroenterology Pub Date : 2024-10-01 Epub Date: 2024-07-31 DOI: 10.1007/s12328-024-02022-w
Manabu Nagayama, Yohei Funayama, Osamu Taniguchi, Kaoru Hatano, Kunihiko Oguro, Jun Owada, Hirotsugu Sakamoto, Tomonori Yano, Randy Scott Longman, Hironori Yamamoto
{"title":"Biologic therapy for ulcerative colitis associated with immune thrombocytopenia.","authors":"Manabu Nagayama, Yohei Funayama, Osamu Taniguchi, Kaoru Hatano, Kunihiko Oguro, Jun Owada, Hirotsugu Sakamoto, Tomonori Yano, Randy Scott Longman, Hironori Yamamoto","doi":"10.1007/s12328-024-02022-w","DOIUrl":"10.1007/s12328-024-02022-w","url":null,"abstract":"<p><p>Ulcerative colitis (UC), a subtype of inflammatory bowel disease, occasionally manifests with extraintestinal manifestations. We present a 51-year-old male with refractory UC and immune thrombocytopenia (ITP) resistant to conventional treatments. The introduction of biologics, ustekinumab or adalimumab, resulted in clinical remission of colitis and improvements in platelet count. This case underscores the efficacy of biologics in managing refractory UC associated with ITP, emphasizing their potential to control intestinal inflammation and address concurrent thrombocytopenia, potentially avoiding surgical intervention.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":"910-914"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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