Clinical Journal of Gastroenterology最新文献_第9页

Gallbladder adenosquamous carcinoma with extensive necrosis mimicking gangrenous cholecystitis and liver abscess. 胆囊腺鳞癌伴广泛坏死，类似坏疽性胆囊炎和肝脓肿。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-06 DOI: 10.1007/s12328-026-02439-5

Marie Sakai, Mayu Uka, Yuri Takemoto, Yuka Ogino, Koichi Yoshimura, Momoka Nagae, Shinichi Shimizu, Yoko Shinno, Takashi Mukai, Takao Hiraki

引用次数: 0

Endoscopic ultrasound-guided biopsy of left and right adrenal metastases enabling pathological diagnosis and genomic profiling after nondiagnostic conventional biopsies: two case reports. 超声内镜引导下左、右肾上腺转移瘤活检，在非诊断性常规活检后进行病理诊断和基因组谱分析：两例报告。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-06 DOI: 10.1007/s12328-026-02430-0

Koichi Soga, Satsuki Otani, Ryotaro Iwamoto, Ou Takagi, Mikako Masuda, Masaru Kuwada, Ikuhiro Kobori, Katsutoshi Sugimoto

{"title":"Endoscopic ultrasound-guided biopsy of left and right adrenal metastases enabling pathological diagnosis and genomic profiling after nondiagnostic conventional biopsies: two case reports.","authors":"Koichi Soga, Satsuki Otani, Ryotaro Iwamoto, Ou Takagi, Mikako Masuda, Masaru Kuwada, Ikuhiro Kobori, Katsutoshi Sugimoto","doi":"10.1007/s12328-026-02430-0","DOIUrl":"https://doi.org/10.1007/s12328-026-02430-0","url":null,"abstract":"Obtaining adequate tissue for histologic diagnoses and genomic testing can be challenging in metastatic lung cancer, particularly when conventional biopsy approaches are nondiagnostic. The study reports an effective salvage strategy using endoscopic ultrasound (EUS)-guided adrenal tissue acquisition in two cases. A 66-year-old woman (case 1) developed recurrent lung adenocarcinoma with progressive metastases to the left adrenal, liver, and lungs following multiple lines of systemic therapy. A percutaneous biopsy of a suspected liver metastasis proved nondiagnostic. Subsequently, transgastric EUS-guided biopsy was performed, which confirmed metastatic adenocarcinoma originating in the lung. Oncomine-based genomic testing detected a human epidermal growth factor receptor 2 exon 20 insertion. Trastuzumab deruxtecan was subsequently introduced, resulting in disease stabilization for 6 months. A 75-year-old man (case 2) developed bilateral pulmonary nodules and a right adrenal mass detected on positron emission tomography. Bronchoscopy failed to yield diagnostic tissue. Following careful review of cross-sectional anatomy, EUS-guided biopsy of the right adrenal gland was safely performed via the duodenal bulb, confirming metastatic squamous cell carcinoma and yielding adequate tissue for genomic testing. EUS-guided adrenal biopsy, including transduodenal sampling of the right adrenal gland, may provide tissue for histopathologic and precision oncology testing, facilitating definitive diagnoses.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carcinoma in adenoma of the minor duodenal papilla completely resected by endoscopic mucosal resection. 十二指肠小乳头腺瘤经内镜粘膜切除术完全切除。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-06 DOI: 10.1007/s12328-026-02432-y

Eisuke Ozawa, Takuji Yamao, Kosuke Takahashi, Mizuki Kitagawa, Masashi Shibata, Satoshi Miuma, Keisuke Iwasaki, Hisamitsu Miyaaki

{"title":"Carcinoma in adenoma of the minor duodenal papilla completely resected by endoscopic mucosal resection.","authors":"Eisuke Ozawa, Takuji Yamao, Kosuke Takahashi, Mizuki Kitagawa, Masashi Shibata, Satoshi Miuma, Keisuke Iwasaki, Hisamitsu Miyaaki","doi":"10.1007/s12328-026-02432-y","DOIUrl":"https://doi.org/10.1007/s12328-026-02432-y","url":null,"abstract":"Adenocarcinoma of the minor duodenal papilla is rare, and most previously reported cases have been treated by pancreaticoduodenectomy. An 82-year-old woman underwent endoscopy for anemia, which revealed a granular, flat-elevated lesion in the descending duodenum, 2 cm proximal to the major papilla. Endoscopic retrograde pancreatography showed leakage of contrast medium from the orifice of the accessory pancreatic duct at the lesion, confirming a tumor of the minor papilla. The initial biopsy showed adenoma, and the lesion was followed. Six months later it had enlarged and become friable, and repeat biopsy was suspicious for adenocarcinoma. Because pancreaticoduodenectomy was considered too invasive given her age and comorbidities, and because the minor papilla-unlike the major papilla-can be lifted by submucosal injection, en-bloc endoscopic mucosal resection was performed for both diagnostic and therapeutic purposes. Histology showed well-differentiated adenocarcinoma arising in adenoma, confined to the mucosa, with tumor-free margins and no lymphovascular invasion. No adverse events occurred, and no recurrence was observed during approximately 5 years of follow-up (endoscopic surveillance up to 2 years); the patient later died of an unrelated cause. Endoscopic mucosal resection may be a minimally invasive option achieving histologically complete resection in selected intramucosal carcinomas of the minor duodenal papilla.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An atypical case with recurrent episodes of pancreatitis: is eosinophilic pancreatitis a diagnosis or a mimic in the spectrum of IgG4-related diseases? A case-based review : Eosinophilic pancreatitis or IGG4-releated disease. 胰腺炎复发的非典型病例：嗜酸性胰腺炎是诊断还是igg4相关疾病谱中的模拟？一项基于病例的综述：嗜酸性胰腺炎或igg4相关疾病

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-06 DOI: 10.1007/s12328-026-02442-w

Burak Okyar, Süha Göksel, Ceren Korkmaz, Okan Dilek, Çağla Okyar, Zeynep Tüzün, Servet Yüce, Emine Duygu Ersözlü

{"title":"An atypical case with recurrent episodes of pancreatitis: is eosinophilic pancreatitis a diagnosis or a mimic in the spectrum of IgG4-related diseases? A case-based review : Eosinophilic pancreatitis or IGG4-releated disease.","authors":"Burak Okyar, Süha Göksel, Ceren Korkmaz, Okan Dilek, Çağla Okyar, Zeynep Tüzün, Servet Yüce, Emine Duygu Ersözlü","doi":"10.1007/s12328-026-02442-w","DOIUrl":"https://doi.org/10.1007/s12328-026-02442-w","url":null,"abstract":"Eosinophilic pancreatitis (EP) is a rare disorder characterized by prominent pancreatic eosinophilic infiltration and often associated with peripheral eosinophilia and elevated IgE. IgG4-related disease (IgG4-RD) may involve the pancreas as type 1 autoimmune pancreatitis, with lymphoplasmacytic infiltration, storiform fibrosis, and increased IgG4-positive plasma cells. Both can mimic pancreatic malignancy. We report a 43-year-old man who underwent distal pancreatectomy in 2016 for suspected cancer and later experienced three episodes of acute pancreatitis. In 2024, modest serum IgG4 elevation (304 mg/dL; reference range, 3-201 mg/dL) and persistent monocytosis prompted re-evaluation of the surgical specimen. Histology showed dense, patchy eosinophilic infiltration with microabscesses and non-storiform fibrosis, while IgG4-positive plasma cells were sparse. These findings favored EP over type 1 autoimmune pancreatitis. This case highlights that EP may occur without peripheral eosinophilia, mimic malignancy and IgG4-RD, and require re-examination of archival tissue. Careful clinicopathological correlation is therefore essential to avoid diagnostic delay and misclassification.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flucytosine-induced colitis mimicking a flare of ulcerative colitis: a diagnostic challenge in pulmonary cryptococcal infection. 氟胞嘧啶引起的模拟溃疡性结肠炎的结肠炎：肺隐球菌感染的诊断挑战。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-06 DOI: 10.1007/s12328-026-02446-6

Kevin Jia, Robert O'Neill, Christina Lee, Yee Lin, Christine Verdon

引用次数: 0

Durable complete response following sequential atezolizumab-bevacizumab and delayed transcatheter arterial embolization in advanced hepatocellular carcinoma. 连续阿特唑单抗-贝伐单抗和延迟经导管动脉栓塞治疗晚期肝细胞癌后的持久完全缓解

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-04 DOI: 10.1007/s12328-026-02438-6

Daichi Takizawa, Keita Kiboshi, Yuki Tamura, Yumeo Tateyama, Mitsuhiko Shibasaki, Hiroki Tojima, Hirotaka Arai, Toshio Uraoka

引用次数: 0

Gastric mucosa-associated lymphoid tissue lymphoma diagnosed following localized gastric AL amyloidosis. 胃粘膜相关淋巴组织淋巴瘤诊断后，局部胃AL淀粉样变。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-04 DOI: 10.1007/s12328-026-02435-9

Mizuki Kameyama, Masaya Iwamuro, Takehiro Tanaka, Ayano Nishio, Chihiro Sakaguchi, Kenta Hamada, Yoshiyasu Kono, Yoshiro Kawahara, Shogen Ohya, Motoyuki Otsuka

{"title":"Gastric mucosa-associated lymphoid tissue lymphoma diagnosed following localized gastric AL amyloidosis.","authors":"Mizuki Kameyama, Masaya Iwamuro, Takehiro Tanaka, Ayano Nishio, Chihiro Sakaguchi, Kenta Hamada, Yoshiyasu Kono, Yoshiro Kawahara, Shogen Ohya, Motoyuki Otsuka","doi":"10.1007/s12328-026-02435-9","DOIUrl":"https://doi.org/10.1007/s12328-026-02435-9","url":null,"abstract":"Gastrointestinal amyloidosis is a rare condition with diverse clinical and endoscopic manifestations. Among these subtypes, localized gastric AL amyloidosis is rare and associated with lymphoproliferative disorders. Here, we report a case of gastric mucosa-associated lymphoid tissue (MALT) lymphoma diagnosed during follow-up of localized gastric AL (κ) amyloidosis. A 65-year-old woman who underwent periodic endoscopic screening was found to have a localized erythematous lesion with erosion in the lower gastric body. Histopathological examination revealed amyloid deposits. Although potassium permanganate treatment suggested AA amyloidosis, immunohistochemical analysis confirmed AL (κ)-type amyloid. Systemic evaluation revealed no evidence of plasma cell dyscrasia, and localized gastric AL amyloidosis was diagnosed. After six months, the lesion regressed, but a newly identified discolored lesion was diagnosed as MALT lymphoma with plasmacytic differentiation. This case highlights the limitations of potassium permanganate-based amyloid typing and raises the possibility of an association between localized AL amyloidosis and lymphoproliferative disorders. These cases require careful endoscopic surveillance.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two cases of repeated upper gastrointestinal bleeding due to chronic disseminated intravascular coagulation associated with aortic aneurysm. 慢性弥散性血管内凝血合并主动脉瘤所致反复上消化道出血2例。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-09-04 DOI: 10.1007/s12328-026-02436-8

Tomoko Terashita, Hiroyoshi Iwagami, Riki Sakano, Shotaro Ueno, Tomoya Kitada, Masayuki Shimoyama, Yasuki Nakatani, Yukitaka Yamashita

引用次数: 0

Left atrial appendage occlusion for bleeding risk control during endoscopic submucosal dissection in patients with chronic atrial fibrillation. 慢性房颤患者内镜下粘膜下剥离术中左心耳闭塞对出血风险的控制。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-08-31 DOI: 10.1007/s12328-026-02434-w

Hiroki Yanase, Ken Inoue, Taku Kano, Osamu Dohi, Naohisa Yoshida, Kazuhiko Uchiyama, Motohiro Kojima, Kan Zen, Satoaki Matoba, Tomohisa Takagi

引用次数: 0

A novel endoscopic approach for refractory gastroesophageal reflux disease after laparoscopic sleeve gastrectomy: endoscopic anti-reflux mucosectomy. 内镜下治疗腹腔镜袖胃切除术后难治性胃食管反流病的新方法：内镜下抗反流粘膜切除术。

IF 0.8

Clinical Journal of Gastroenterology Pub Date : 2026-08-24 DOI: 10.1007/s12328-026-02431-z

Keita Kojima, Kazuko Yokota, Toshimichi Tanaka, Keigo Yokoi, Ken Kojo, Hirohisa Miura, Takahiro Yamanashi, Takeo Sato, Takeshi Naitoh

{"title":"A novel endoscopic approach for refractory gastroesophageal reflux disease after laparoscopic sleeve gastrectomy: endoscopic anti-reflux mucosectomy.","authors":"Keita Kojima, Kazuko Yokota, Toshimichi Tanaka, Keigo Yokoi, Ken Kojo, Hirohisa Miura, Takahiro Yamanashi, Takeo Sato, Takeshi Naitoh","doi":"10.1007/s12328-026-02431-z","DOIUrl":"https://doi.org/10.1007/s12328-026-02431-z","url":null,"abstract":"Introduction: Gastroesophageal reflux disease (GERD) is a relatively common complication following laparoscopic sleeve gastrectomy (LSG), with refractory GERD often necessitating revisional surgery. We report two cases of refractory GERD after LSG that were managed with endoscopic anti-reflux mucosectomy (ARMS).Case presentation: Case 1: A 58-year-old woman with morbid obesity (BMI 42.2 kg/m2) complicated by hypertension, dyslipidemia, and sleep apnea syndrome underwent LSG. Postoperatively, vomiting symptoms developed approximately two weeks after LSG and worsened over the subsequent year. ARMS was performed one year and three months after LSG. Two months after ARMS, the patient achieved symptomatic and endoscopic improvement while continuing P-CAB therapy. Case 2: A 53-year-old woman with morbid obesity (BMI 41.4 kg/m2) complicated by diabetes, dyslipidemia, hypertension, and sleep apnea syndrome underwent LSG. Postoperatively, she developed medication-refractory GERD. Revisional Roux-en-Y gastric bypass was considered; however, given her history of multiple abdominal surgeries and her preference, ARMS was performed two years after LSG. Two years after ARMS, the patient remained in symptomatic and endoscopic remission, with an improved GERD-HRQL score.Conclusions: ARMS may be a valuable treatment option for GERD after LSG, potentially bridging medical therapy and revisional surgery while reducing patient burden.","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0