Clinical Medicine Insights. Case Reports最新文献_第6页

Microangiopathic Hemolytic Anemia as a Paraneoplastic Syndrome in a Patient with Metastatic Gastric Cancer. 转移性胃癌患者的副肿瘤综合征--微血管病性溶血性贫血

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-08-14 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241271534

Shahd T Natsheh, Tuqa Abu Ihlayel, Rawda Qasrawi, Qusai A Alsalah, Ahmad G Hammouri, Amer Zughayyer, Hasan Arafat

{"title":"Microangiopathic Hemolytic Anemia as a Paraneoplastic Syndrome in a Patient with Metastatic Gastric Cancer.","authors":"Shahd T Natsheh, Tuqa Abu Ihlayel, Rawda Qasrawi, Qusai A Alsalah, Ahmad G Hammouri, Amer Zughayyer, Hasan Arafat","doi":"10.1177/11795476241271534","DOIUrl":"10.1177/11795476241271534","url":null,"abstract":"Cancer-associated microangiopathic hemolytic anemia (CA-MAHA) is a rare paraneoplastic syndrome. The most effective approach to treating CA-MAHA is to address the underlying malignancy. Documented cases of CA-MAHA are limited to fewer than 50 patients in the literature. Herein, we present a 51-year-old female patient who developed CA-MAHA as a complication of gastric adenocarcinoma. Despite receiving neoadjuvant and adjuvant chemotherapy for gastric cancer, the patient experienced disease progression with metastatic lesions in the liver, pancreas, and other sites. This report highlights the challenges in diagnosing and distinguishing CA-MAHA from other similar conditions such as disseminated intravascular coagulation (DIC), hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP), and rheumatological paraneoplastic syndromes. Additionally, it concludes that CA-MAHA is associated with a poor prognosis and limited clinical benefit from treatment, emphasizing the need for early diagnosis and effective management strategies.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241271534"},"PeriodicalIF":0.8,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141986712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peritonitis Secondary to Ruptured Hydatid Liver Cyst in a Young Postpartum Woman: A Rare Case Report. 一名年轻产后妇女继发于肝包虫囊肿破裂的腹膜炎：罕见病例报告

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-08-14 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241271561

Messaoud Ola, Horache Kenza, Jidal Manal, Cherraqi Amine, El Aoufir Omar, Laamrani Fatima Zahra, Jroundi Laila

{"title":"Peritonitis Secondary to Ruptured Hydatid Liver Cyst in a Young Postpartum Woman: A Rare Case Report.","authors":"Messaoud Ola, Horache Kenza, Jidal Manal, Cherraqi Amine, El Aoufir Omar, Laamrani Fatima Zahra, Jroundi Laila","doi":"10.1177/11795476241271561","DOIUrl":"10.1177/11795476241271561","url":null,"abstract":"Hydatid disease, caused primarily by Echinococcus granulosus, is prevalent in regions where livestock farming is common. Although typically considered benign, ruptured hydatid cysts into the abdominal cavity present a rare but severe complication requiring urgent surgical intervention. We hydatid liver cyst, emphasizing the unprecedented nature of this occurrence, as it has never been reported in the literature before. The case underscores the role of computed tomography (CT) imaging in diagnosis and multidisciplinary management involving emergency physicians, radiologists, anesthetists, and surgeons. Key points highlighted include the rarity of postpartum hydatid cyst rupture, the diagnostic utility of CT scans, and the necessity of immediate surgical intervention. Surgical strategies include conservative techniques and intraoperative lavage with hypertonic saline solution to prevent recurrence. Postoperative albendazole therapy and regular follow-up aid in preventing recurrence and early detection of complications. This case underscores the importance of suspecting ruptured hydatid cysts in postpartum women with underlying hepatic hydatid cyst and features of peritonitis, necessitating prompt recognition and management of complications in hydatid disease.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241271561"},"PeriodicalIF":0.8,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating the 'Triangle of Death': A Multidisciplinary Approach in Severe Multi-Trauma Management. 驾驭 "死亡三角"：严重多重创伤管理中的多学科方法。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-08-13 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241271544

Yushan Zhang, Fuxia Jian, Liang Wang, Hao Chen, Zhengbin Wu, Shili Zhong

引用次数: 0

Recurrent Hypoglycemia in a 67-Year-Old Woman with CD5- Positive Diffuse Large B-Cell Lymphoma. 一名患有 CD5 阳性弥漫性大 B 细胞淋巴瘤的 67 岁女性反复出现低血糖。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-08-13 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241271540

Jing Zhang, Jieyuzhen Qiu, Lipan Wu, Lin Shen, Qin Gu, Wen Tan

引用次数: 0

An Unusual Cause of Lymphadenopathy: Rosai Dorfman Disease in a 7-Year-Old Female Zambian Child: Case Report and Literature Review. 淋巴腺病的不寻常病因：一名 7 岁赞比亚女婴的罗赛-多夫曼病：病例报告和文献综述。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-07-30 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241265279

Hellen M'hango, Uzima Chirwa, Zoran Muhimba, Rose Chilufya, Juliet Mulopwe, Chibamba Mumba, Evans Mpabalwani

引用次数: 0

Unusual Presentation of Thoracic Chordoma with Spinal Epidural Hematoma: A Rare Case Report and PRISMA-Driven Systematic Review. 胸脊索瘤伴脊髓硬膜外血肿的不寻常表现：罕见病例报告和 PRISMA 驱动的系统综述。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-07-28 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241266099

Khaled Alsayed Abualkhair, Asmaa F Sharif, Hadeel Eid, Ahmed G ElToukhy, Mohammad Ezzat, Mahmoud M Taha

{"title":"Unusual Presentation of Thoracic Chordoma with Spinal Epidural Hematoma: A Rare Case Report and PRISMA-Driven Systematic Review.","authors":"Khaled Alsayed Abualkhair, Asmaa F Sharif, Hadeel Eid, Ahmed G ElToukhy, Mohammad Ezzat, Mahmoud M Taha","doi":"10.1177/11795476241266099","DOIUrl":"10.1177/11795476241266099","url":null,"abstract":"A chordoma is a slow growing, locally invasive, low-grade tumor belonging to the sarcoma family. It mainly affects the sacrum and skull base. We present a case of thoracic chordoma initially presented with epidural hematoma (EDH), which is a rare clinical entity. We reported this case, and also performed a PRISMA-driven systematic review to summary the similar cases in the literature. This review includes the clinical characteristics and outcome of thoracic chordoma. Our case involves a 60-year-old male who, despite no history of trauma, presented with acute paraparesis. An epidural hematoma was identified at T6 level, leading to a surgical intervention involving T4-6 laminectomy and fixation. Six months subsequent to surgery, the patient experienced progressive lower limb weakness and spasticity. Computed tomography (CT) exhibited erosion of T6 and an associated aggressive mass. Magnetic resonance imaging (MRI) revealed a large heterogenous soft tissue mass arising from the vertebral body and right pedicle of D6, protruding in the epidural space and compressing the spinal cord focally at this level. The mass measured approximately 5 × 4 × 3.5 cm. Magnetic resonance myelography indicated a filling defect at T5-6 level, confirming the intraspinal location of the soft tissue lesion. Complete excision of the mass confirmed the diagnosis of thoracic chordoma. Postoperative follow-up demonstrated notable improvement in the lower limb spasticity and paraparesis, and the patient started adjuvant radiotherapy. This case underscores the importance of maintaining a high index of suspicion when evaluating presentations resembling EDH.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241266099"},"PeriodicalIF":0.8,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Intraoperative and Pathological Findings Related to Computed Tomography Angiography Spot Signs in Intracerebral Hemorrhage Patients: A Case Report. 与脑出血患者计算机断层扫描血管造影斑点征相关的术中和病理新发现：病例报告。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-07-27 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241265275

Qiang Zhang, Zhi Chen, Yujie Chen, Zhouyang Jiang, Wenyan Li, Yingpei Li, Zhuo Yao, Wenchao Fu, Yanyu Fang, Mo Li, Yin Niu

{"title":"Novel Intraoperative and Pathological Findings Related to Computed Tomography Angiography Spot Signs in Intracerebral Hemorrhage Patients: A Case Report.","authors":"Qiang Zhang, Zhi Chen, Yujie Chen, Zhouyang Jiang, Wenyan Li, Yingpei Li, Zhuo Yao, Wenchao Fu, Yanyu Fang, Mo Li, Yin Niu","doi":"10.1177/11795476241265275","DOIUrl":"10.1177/11795476241265275","url":null,"abstract":"Introduction: A spot sign on computed tomography angiography (CTA) scan is a widely recognized radiographic indicator of primary intracerebral hemorrhage (ICH) used to predict early hematoma expansion. Nonetheless, recent multicenter studies have indicated that its predictive value for hematoma expansion is not as significant as previously stated. Therefore, identifying the reasons for the poor performance of these studies is imperative.Case presentation: A 48-year-old man presented with a 9-hour history of alalia and right limb hemiplegia. Noncontrast computed tomography (CT) revealed a hematoma in the left frontal lobe, while CTA showed a spot sign within the hematoma, leading to a diagnosis of frontal lobe hemorrhage. During the surgical procedure, a blood clot was removed, revealing the presence of 3 mm of saccular tissue resembling an aneurysm. The process of exposing its complete form resulted in its rupture and bleeding. The location of this tissue at the top of the hematoma cavity corresponded to the CTA spot sign. Pathological examination confirmed that the characteristics of the tissue wall were consistent with those of a pseudoaneurysm.Conclusion: This case suggests that more stringent identification criteria should be established in studies predicting ICH expansion using the spot sign on CTA to differentiate and exclude pseudoaneurysms, thereby improving the accuracy of predicting early hematoma expansion using the CTA spot sign.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241265275"},"PeriodicalIF":0.8,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11283649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delivery-First Strategy Followed by Endovascular Repair to Treat Pregnant Woman With Acute Complicated Type B Aortic Dissection. 采用先分娩后血管内修复的策略治疗急性并发 B 型主动脉夹层孕妇。

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-07-27 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241265270

Chen Ming Huang, Chen-Hua Wang, Hao-Chin Wang, Yi-Ting Chuang, Shu-Yi Sung, Chi-Yuan Liao

引用次数: 0

Silent Case of Pediatric Osteoarticular Tuberculosis: A Case Report and Review of the Literature. 小儿骨关节结核沉默病例：病例报告与文献综述

IF 0.8

Clinical Medicine Insights. Case Reports Pub Date : 2024-06-22 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241263683

Mohammad Ali Alshrouf, Zuhdi O Elifranji, Sereen Halayqeh, Munther Al-Saber, Abdulrahman M Karam

{"title":"Silent Case of Pediatric Osteoarticular Tuberculosis: A Case Report and Review of the Literature.","authors":"Mohammad Ali Alshrouf, Zuhdi O Elifranji, Sereen Halayqeh, Munther Al-Saber, Abdulrahman M Karam","doi":"10.1177/11795476241263683","DOIUrl":"10.1177/11795476241263683","url":null,"abstract":"Introduction: Tuberculosis (TB) is one of the most prevalent infectious diseases globally, often presenting with nonspecific symptoms that can obscure diagnosis, especially when it manifests in uncommon sites such as osteoarticular tuberculosis (OA-TB).Case presentation: We report a rare case of a 9-year-old male diagnosed with right knee tuberculosis after enduring severe symptoms for several months. Despite multiple negative biopsies and aspirates during initial debridement surgeries, a biopsy taken 6 months later confirmed the presence of Mycobacterium tuberculosis (MTB). The patient was subsequently treated with debridement and anti-tubercular therapy.Conclusion: This case underscores the critical need to consider tuberculosis in patients presenting with chronic bone pain to avoid misdiagnosis, particularly in the developing world. The atypical presentation of osteoarticular tuberculosis in this young patient emphasizes the need for healthcare professionals to recognize subtle symptoms. Advanced imaging studies like MRI and microbiological evaluations, including site biopsies, are essential for accurate diagnosis. Increased awareness and collaborative research are crucial to improving the understanding and management of pediatric osteoarticular tuberculosis and extrapulmonary tuberculosis.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241263683"},"PeriodicalIF":0.8,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11193920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intracranial Infections Arising From an Odontogenic Infection: A Report of 2 Cases. 牙源性感染引起的颅内感染：2 个病例的报告。

IF 1

Clinical Medicine Insights. Case Reports Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI: 10.1177/11795476241261883

Ikram Attouchi, Nouha Dammak, Hela Zouaghi, Mohamed Ben Khelifa

{"title":"Intracranial Infections Arising From an Odontogenic Infection: A Report of 2 Cases.","authors":"Ikram Attouchi, Nouha Dammak, Hela Zouaghi, Mohamed Ben Khelifa","doi":"10.1177/11795476241261883","DOIUrl":"10.1177/11795476241261883","url":null,"abstract":"Introduction: Intracranial empyema is a rare but serious and life-threatening infection. It is an accumulation of purulent material in the subdural or extradural space leading to development of subdural empyema or intracranial epidural abscess, respectively. The incidence of morbidity and mortality is high because the diagnosis is often unsuspected. Infections of dental origin could be responsible for such condition.Case reports: A 22-year-old female and 30-year-old male patients, both with no significant medical history, presented with subdural empyema and intracranial epidural abscess, respectively, both complicating pan-sinusitis of dental origin. Successful outcomes were achieved with surgical drainage of the lesions, antibiotic therapy, and extraction of affected teeth. Female patient underwent further management for neurological sequelae, while male patient was discharged without neurological complications.Discussion: Intracranial suppuration of odontogenic origin is an uncommon but extremely serious complication. The most common dental origins are caries with periapical involvement and periodontitis. Wisdom tooth extraction is the most common preceding dental procedure for this infection. A multidisciplinary approach is essential for the identification and treatment of suspected oral sources. Antibiotic therapy with surgical approach is the gold standard treatment.Conclusion: This sequel to odontogenic infection is quite rare, but it can be prevented by a good oral hygiene and removal of abscessed teeth.","PeriodicalId":10357,"journal":{"name":"Clinical Medicine Insights. Case Reports","volume":"17 ","pages":"11795476241261883"},"PeriodicalIF":1.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0