Clinical nutrition ESPEN最新文献

{"title":"Bowel preparation for elective colorectal resection: multi-treatment machine-learning analysis on 6,241 cases from the prospective iCral cohort.","authors":"Marco Catarci ∗","doi":"10.1016/j.clnesp.2024.10.011","DOIUrl":"10.1016/j.clnesp.2024.10.011","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Page 493"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143129133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of high-dose dexamethasone in postoperative opioid use and perioperative glycaemia in FAST TRACK primary hip arthroplasty","authors":"Montserrat Tió , Josefina Fabian , Nuria Martin , Yocelin Saavedra , Elisabet Ripoll , Jenaro Fernandez-Valencia , Tomas Cuñat ∗","doi":"10.1016/j.clnesp.2024.10.040","DOIUrl":"10.1016/j.clnesp.2024.10.040","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Pages 505-506"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative immunonutrition and postoperative outcomes in patients with cancer undergoing major abdominal surgery: Retrospective cohort study","authors":"Mauricio Chona Chona ,&nbsp;Lina Maria López Basto ,&nbsp;Carolina Pinzón Ospina ,&nbsp;Ana Cristina Pardo Coronado ,&nbsp;María Paula Guzmán Silva ,&nbsp;Marjorie Marín ,&nbsp;Alvaro Vallejos ,&nbsp;Gloria Esperanza Castro Osmán ,&nbsp;Carlos Saavedra ,&nbsp;Jorge Díaz Rojas ,&nbsp;Jorge Medina-Parra ,&nbsp;Ricardo Alfonso Merchán-Chaverra","doi":"10.1016/j.clnesp.2024.12.011","DOIUrl":"10.1016/j.clnesp.2024.12.011","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Surgical resection is a first-line treatment for patients with cancer, but preoperative malnutrition is a risk factor for postoperative complications. This study aimed to evaluate the association between preoperative administration of an immunonutrition regimen and postoperative clinical outcomes in patients with cancer undergoing major abdominal surgery.</div></div><div><h3>Methods</h3><div>The Surgical Prehabilitation Multimodal Oncology (SUPREMO) retrospective cohort study, conducted from January 2021 to December 2023, included patients with cancer undergoing major abdominal surgery. Patients were categorized based on whether they received a complete immunonutrition regimen or an incomplete or no regimen. Demographic and clinical data were extracted from electronic health records for descriptive analysis. Logistic regression was used to assess the impact of immunonutrition on the risk of infectious complications, with clinical and demographic variables as explanatory factors.</div></div><div><h3>Results</h3><div>A total of 620 patients were included, with 49 % receiving a complete preoperative immunonutrition regimen. Bivariate analysis indicated that complete regimen administration was associated with lower intensive care unit (ICU) admission, invasive mechanical ventilation (IMV), and vasopressor support requirements (<em>p</em> = 0.005, <em>p</em> = 0.019, and <em>p</em> = 0.032, respectively). The logistic regression model showed a significant reduction in in-hospital infectious complications (odds ratio 0.54, 95 % confidence interval 0.31–0.98; <em>p</em> = 0.044).</div></div><div><h3>Conclusion</h3><div>Administering a complete preoperative immunonutrition regimen may be associated with reduced infectious complications, ICU and IMV requirements, and vasopressor support use.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Pages 324-330"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calf circumference may complement the nutritional assessment of children under 10 in the paediatric intensive care unit","authors":"Rafaela Rodrigues Vieira ,&nbsp;Patrícia Zamberlan","doi":"10.1016/j.clnesp.2024.12.020","DOIUrl":"10.1016/j.clnesp.2024.12.020","url":null,"abstract":"<div><h3>Background</h3><div>Nutritional intervention during hospitalisation is vital in managing of children and adolescents in intensive care. In this context, body composition measurements, such as mid-upper arm circumference (MUAC), can help improve the accuracy of nutritional assessments. However, using MUAC has some limitations. Calf circumference (CC) is a straightforward, inexpensive, and easily obtainable measurement. However, no reference values currently exist for CC in paediatric patients.</div></div><div><h3>Aims</h3><div>To describe the nutritional monitoring of critically ill children and adolescents in the Paediatric Intensive Care Unit (PICU) using CC.</div></div><div><h3>Methods</h3><div>Patients aged 6 months to 18 years old who were admitted to the PICUs participated in the study. Two MUAC and CC measurements were performed: one in the first 48 h of admission to the PICU and another after 7 days. The percentage change between the two measurements was compared. Information was also evaluated about demographic and outcome data. Analyses were conducted with all patients included in the sample collectively and subdivided by age (&lt;10 years and ≥10 years).</div></div><div><h3>Results</h3><div>Two hundred and eleven patients underwent anthropometric assessment on admission, and the sample for comparative analyses consisted of 103 patients (after discharges and deaths). MUAC and CC significantly decreased in the first week of hospitalisation. A positive weak correlation was found between the percentage change in the MUAC and CC only for individuals under 10 years old and for the total sample, but not for adolescents. The all age group and children under 10 years old showed a greater reduction in CC than in MUAC. The same did not occur for adolescents.</div></div><div><h3>Conclusions</h3><div>Calf circumference may be a promising method for nutritional monitoring of critically ill children in Paediatric Intensive Care Units because it can indicate signs of depletion earlier than mid-upper arm circumference. These results are more meaningful for children than for adolescents.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Pages 445-452"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact Of Enhanced Recovery After Surgery Protocol Compliance On Outcome After Pancreatic Surgery – Results From A Certified Eras Center","authors":"Thilo Welsch ∗,&nbsp;Alina Ritter,&nbsp;Freya Brodersen,&nbsp;Tobias Schneider,&nbsp;Faik Güntac Uzunoglu,&nbsp;Felix Nickel,&nbsp;Mara R. Goetz,&nbsp;Jana Bardenhagen,&nbsp;Thilo Hackert,&nbsp;Jakob R. Izbicki","doi":"10.1016/j.clnesp.2024.10.043","DOIUrl":"10.1016/j.clnesp.2024.10.043","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Page 507"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143175630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dawn-to-dusk intermittent fasting is associated with overexpression of autophagy genes: A prospective study on overweight and obese cohort","authors":"Lara J. Bou Malhab ,&nbsp;Mohamed I. Madkour ,&nbsp;Dana N. Abdelrahim ,&nbsp;Leen Eldohaji ,&nbsp;Maha Saber-Ayad ,&nbsp;Nabil Eid ,&nbsp;Wael M. Abdel-Rahman ,&nbsp;MoezAlIslam E. Faris","doi":"10.1016/j.clnesp.2024.11.002","DOIUrl":"10.1016/j.clnesp.2024.11.002","url":null,"abstract":"<div><h3>Aim and background</h3><div>A growing body of evidence supports the impact of intermittent fasting (IF) on longevity and healthy aging via the modulation of autophagy genes. The activation of the catabolic autophagic machinery (<em>LAMP2, LC3B, ATG5</em>, and <em>ATG4D)</em> has protective effects against degenerative aging and chronic diseases. This research examined the changes in the expression of the aforementioned genes upon the observance of dawn-to-dusk IF among metabolically healthy participants with overweight and obesity.</div></div><div><h3>Methods</h3><div>Fifty-one (51) participants (36 males and 15 females, 38.84 ± 11.73 years) with overweight and obesity (BMI = 29.75 ± 5.04 kg/m²) were recruited and monitored before and at the end of the commencement of the four-week IF. Six healthy subjects with normal BMI (21.4 ± 2.20 kg/m²) were recruited only to standardize the reference for normal levels of gene expressions. At the two time points, anthropometric, biochemical, and dietary assessments were performed, and <em>LAMP2, LC3B, ATG5</em>, and <em>ATG4D</em> gene expressions were assessed using qRT-PCR on RNA extracted from whole blood samples.</div></div><div><h3>Results</h3><div>At the end of IF, and compared to the pre-fasting levels, the relative gene expressions among participants with overweight/obesity were significantly increased for the three autophagy genes <em>LAMP2</em>, <em>LC3B,</em> and <em>ATG5</em>, with increments of about 4.2 folds, 1.9-fold, and 1.4-fold, respectively. In contrast, the increase in the <em>ATG4D</em> gene was not significant. Concomitantly, significant decreases were found in body weight, BMI, fat mass, body fat percent, hip and waist circumferences, LDL, IL-6, and TNF-a (<em>P</em> &lt; <em>0.05</em>), While HDL, IL-10, and CD163 significantly increased (<em>P</em> &lt; <em>0.05</em>). Binary logistic regression analysis for genetic expressions showed no significant association between high-energy intake, waist circumference, or obesity and the four gene expressions.</div></div><div><h3>Conclusions</h3><div>Four consecutive weeks of dawn-to-dusk IF of Ramadan is associated with the upregulation of autophagy gene expressions in participants with overweight/obesity, and this may explain, at least in part, its favorable short-term temporal metabolic and health-improving effects on early aging-related markers. Hence, IF presumably may entail a protective impact against early markers of aging and metabolic diseases in participants with overweight/obesity.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Pages 209-217"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of breakfast skipping and sleep disorders on glycemic control, cardiovascular risk, and weight loss in type 2 diabetes","authors":"Tatiana Palotta Minari ,&nbsp;Carolina Freitas Manzano ,&nbsp;Louise Buonalumi Tácito Yugar ,&nbsp;Luis Gustavo Sedenho-Prado ,&nbsp;Tatiane de Azevedo Rubio ,&nbsp;Lúcia Helena Bonalumi Tácito ,&nbsp;Antônio Carlos Pires ,&nbsp;José Fernando Vilela-Martin ,&nbsp;Luciana Neves Cosenso-Martin ,&nbsp;Nelson Dinamarco Ludovico ,&nbsp;André Fattori ,&nbsp;Juan Carlos Yugar-Toledo ,&nbsp;Heitor Moreno ,&nbsp;Luciana Pellegrini Pisani","doi":"10.1016/j.clnesp.2024.11.026","DOIUrl":"10.1016/j.clnesp.2024.11.026","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Meal timing is an emerging branch of science that investigates the influence of eating patterns on the circadian rhythm and overall health. There are still discrepancies in the literature as to whether late distribution of food intake and sleep disorders could impact biochemical, anthropometric, and cardiovascular markers<strong>.</strong> The objectives of this study were firstly observe skipping breakfast and sleep disorders over 12 months. Secondarily, analyze the individual influence of these findings on changes biochemical, anthropometric, and cardiovascular markers during the same period.</div></div><div><h3>Methods</h3><div>This descriptive study is part of a tertiary analysis in a recently published study. This research recruited 84 participants with Type 2 Diabetes (T2D) who were divided: Control-40 participants received only medical care; Intervention-44 participants received the same medical care along with nutritional assessment. Consultations occurred quarterly over 12th months, and a follow-up was conducted after 3 months. For influence analysis, non-normal variables were compared using Mann–Whitney, while normal variables were compared using unpaired t-tests. In all instances, α = 0.05 and P &lt; 0.05 were adopted.</div></div><div><h3>Results</h3><div>Analysis revealed a high percentage of patients in both groups who skipped breakfast, slept less than 6 h, and experienced nighttime awakenings during the 1st visit. By the 12th month, there was deterioration in all data in the control group and significant improvement in the intervention group. Those with sleep disturbances also had lower HDL-cholesterol (HDL-C) values (p = 0.0054). For the other analyzes no significant differences were found.</div></div><div><h3>Conclusion</h3><div>Participants who skipped breakfast and had more nocturnal awakenings possibly had worse glycemic and weight control, but this difference was not statistically significant and only trends were observed. Sleep disorders could affect HDL-C levels. However, the influence analysis does not establish a causal relationship and more clinical trials are needed to analyze this topic on T2D.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Pages 172-181"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of International Enhanced Recovery After Surgery (ERAS) Outcomes: An ERAS Interactive Audit System (EIAS) Database Study","authors":"Gregg Nelson ∗ ,&nbsp;Abby Thomas ,&nbsp;Steven P. Bisch ,&nbsp;Hans D. de Boer ,&nbsp;Martin Hubner ,&nbsp;Khara Sauro","doi":"10.1016/j.clnesp.2024.10.013","DOIUrl":"10.1016/j.clnesp.2024.10.013","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Page 493"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143176415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Paradoxical Relationship Among Diabetes Mellitus, Osteoporosis and Sarcopenia: The PARADOS Study","authors":"Tülay Tiftik ,&nbsp;Murat Kara ,&nbsp;Cevriye Mülkoğlu ,&nbsp;İrem Çiftçi ,&nbsp;Ömer Faruk Çelik ,&nbsp;Mahmut Esad Durmuş ,&nbsp;Özgür Kara ,&nbsp;Şerife Mehlika Kuşkonmaz ,&nbsp;Hakan Genç ,&nbsp;Bayram Kaymak ,&nbsp;Levent Özçakar","doi":"10.1016/j.clnesp.2024.12.009","DOIUrl":"10.1016/j.clnesp.2024.12.009","url":null,"abstract":"<div><h3>Introduction</h3><div>Type 2 diabetes mellitus (DM), osteoporosis (OP) and sarcopenia are major public health problems related with higher fall/fracture risks, morbidity and mortality. Due to the lack of a comprehensive analysis among OP, sarcopenia and DM; we aimed to explore the relationships between DM and the aforementioned conditions in postmenopausal women.</div></div><div><h3>Methods</h3><div>This cross-sectional study included postmenopausal women who consecutively admitted to the Departments of Physical &amp; Rehabilitation Medicine, and Endocrinology and Metabolism. Demographic data, nutrition/cognition status and frailty scores of the participants were recorded. Sarcopenia-related parameters including, anterior thigh muscle thickness, handgrip strength, chair stand test, gait speed, and one-leg stand test (OLST) were measured. ISarcoPRM algorithm was used for the diagnosis of sarcopenia.</div></div><div><h3>Results</h3><div>A total of 444 postmenopausal women were consecutively enrolled. DM patients (<em>N</em> = 158) had higher frequency of sarcopenia (23.4 % vs. 12.9 %), but lower frequency of OP (33.5 % vs. 50.7 %) than controls (both <em>p</em> &lt; 0.01). As regards regression analyses; menopause duration was positively (OR: 1.054, 95 % CI 1.030–1.077), but weight (OR: 0.957, 95 % CI 0.940–0.975) and DM (OR: 0.477, 95 % CI 0.310–0.733) were negatively related with OP (all <em>p</em> &lt; 0.001). On the other hand, age (OR: 1.094, 95 % CI 1.056–1.133), body mass index (OR: 1.131, 95 % CI 1.067–1.198), and DM (OR: 1.887, 95 % CI 1.107–3.218) were positively related with sarcopenia (all <em>p</em> &lt; 0.05). In addition, age (β = −0.355, <em>p</em> &lt; 0.001), body mass index (β = −0.108, <em>p</em> = 0.021) and DM (β = −0.209, <em>p</em> &lt; 0.001) were negatively related with OLST values.</div></div><div><h3>Conclusion</h3><div>DM has paradoxical associations with bone mass and muscle mass/function. Although it has negative relationship with OP (about two times lower odds), it has positive relationship with sarcopenia (about two times higher odds).</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Pages 258-263"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Enhanced Recovery After Surgery Compliance on Venous Thromboembolism Rates","authors":"Kristin Black,&nbsp;Abby Thomas,&nbsp;Khara Sauro,&nbsp;Gregg Nelson ∗","doi":"10.1016/j.clnesp.2024.10.009","DOIUrl":"10.1016/j.clnesp.2024.10.009","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"65 ","pages":"Page 492"},"PeriodicalIF":2.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}