Clinical nutrition ESPEN最新文献

{"title":"Reply - Letter to the Editor: \"The metabolic Penalty of time: Nutritional vulnerability and cardiovascular risk in the shift work economy\".","authors":"Luiz Antônio Alves de Menezes-Júnior","doi":"10.1016/j.clnesp.2025.06.018","DOIUrl":"10.1016/j.clnesp.2025.06.018","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between metabolic dysfunction-associated steatotic liver disease and sarcopenia: A systematic review and meta-analyses","authors":"Ninglin Xia ,&nbsp;Jiwei Wang ,&nbsp;Qian Lu ,&nbsp;Xue Fan ,&nbsp;Zhenzhou Jiang ,&nbsp;Qinwei Yu","doi":"10.1016/j.clnesp.2025.06.027","DOIUrl":"10.1016/j.clnesp.2025.06.027","url":null,"abstract":"<div><h3>Background and aims</h3><div>Metabolic dysfunction-associated steatotic liver disease (MASLD) and Sarcopenia are highly prevalent health conditions in the world. Our objective was designed to quantify the relationship between the diagnosis of sarcopenia, sarcopenia and the risk of MASLD.</div></div><div><h3>Methods</h3><div>Web of Science, PubMed, Embase, and OVID were systematically searched from inception to 10 March, 2024, to identify all relevant studies.</div></div><div><h3>Results</h3><div>63 studies met the inclusion criteria, encompassing 288,583 participants. Our findings revealed that the risk of MASLD increased in subjects with sarcopenia (OR: 1.37, [95%CI 1.23,1.51]). In MASLD patients, the levels of skeletal muscle index (SMI) (SMD: −0.26, [95%CI -0.34, −0.18]) and gait speed (SMD: −0.17, [95%CI -0.27, −0.06]) were lower than in normal individuals. Moreover, a higher risk of MASLD was associated with decreased SMI (OR: 0.73, [95%CI 0.66, 0.79], decreased muscle strength (OR: 0.97, [95%CI 0.93, 1.00]). Additionally, the risk of advanced liver fibrosis (OR: 1.47, [95%CI 1.23,1.71]), mortality rate (RR: 1.15, [95%CI 1.09, 1.20]) and all-cause mortality (HR: 1.30, [95%CI 1.13,1.47]) increased in MASLD patients with sarcopenia.</div></div><div><h3>Conclusion</h3><div>Sarcopenia individuals have higher occurrence risk of MASLD. Meanwhile, the patients with low SMI and low muscle strength have higher occurrence risk of MASLD. Furthermore, sarcopenia individuals have higher occurrence risk of MASLD advanced stages including liver fibrosis or mortality. Our study suggested that clinicians should be vigilant about symptoms of sarcopenia, such as SMI, gait speed and muscle strength in patients with MASLD, detect susceptible populations early, and reduce the risk of poor prognosis.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Pages 679-690"},"PeriodicalIF":2.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The metabolic penalty of time: Nutritional vulnerability and cardiovascular risk in the shift work economy.","authors":"Alina Yang","doi":"10.1016/j.clnesp.2025.06.019","DOIUrl":"10.1016/j.clnesp.2025.06.019","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic impact of low muscularity in metastatic and recurrent head and neck cancer: Insights from C3-based assessments","authors":"Larissa Ariel Oliveira Carrilho ,&nbsp;Livia Dias Guerra ,&nbsp;Rafaella Caroline de Lellis Moreira ,&nbsp;Fabiana Lascala Juliani ,&nbsp;Fernanda Silva Santos ,&nbsp;Daniela Morais de Holanda Padilha ,&nbsp;Fabíola Furtuoso Zaperlão ,&nbsp;Sandra Regina Branbilla ,&nbsp;Vivian Naomi Horita ,&nbsp;Davi Magalhães Leite Novaes ,&nbsp;Lígia Moraes Antunes-Correa ,&nbsp;Carmem Silvia Passos Lima ,&nbsp;Maria Carolina Santos Mendes ,&nbsp;José Barreto Campello Carvalheira","doi":"10.1016/j.clnesp.2025.06.029","DOIUrl":"10.1016/j.clnesp.2025.06.029","url":null,"abstract":"<div><div>Head and Neck Cancer (HNC) patients often experience a range of symptoms due to disease which can lead to low energy and protein intake. This scenario can impact body composition as the quality and quantity of muscularity and adiposity changes. This work aims to evaluate the impact of muscularity on the overall survival (OS) of patients with metastatic HNC. This is a retrospective and analytical study, with the population studied being patients diagnosed with metastatic or recurrent HNC, between January 2010 and December 2018, treated at the Clinical Oncology outpatient clinic of the Hospital de Clínicas of the Universidade Estadual de Campinas. To assess body composition, CT images were used at the level of the third cervical vertebra (C3), with the areas of muscle tissue and adipose tissue. The total population included in the sample was 101 patients diagnosed with metastatic or recurrent HNC. It has been shown that low muscularity is associated with the elderly population over 70 years old and with a lower BMI value, below 18.5. The population with low muscularity had a lower amount of total adipose tissue and total adipose tissue index, as well as a lower amount of skeletal muscle and skeletal muscle index in relation to normal muscularity, making it possible to conclude that low muscularity in patients with metastatic or recurrent HNC is an independent factor for mortality.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Pages 767-773"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Comment on “Healthy lifestyle indices are associated with breast cancer immunophenotypes in women”","authors":"Qi Xu,&nbsp;Yuwan Gao","doi":"10.1016/j.clnesp.2025.06.021","DOIUrl":"10.1016/j.clnesp.2025.06.021","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Page 668"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 15-year cohort study of self-reported fermented soybean (natto) intake and all-cause mortality in elderly men","authors":"Yuki Fujita ,&nbsp;Katsuyasu Kouda ,&nbsp;Junko Tamaki ,&nbsp;Takahiro Tachiki ,&nbsp;Etsuko Kajita ,&nbsp;Jong-Seong Moon ,&nbsp;Nozomi Okamoto ,&nbsp;Masayuki Iki","doi":"10.1016/j.clnesp.2025.06.017","DOIUrl":"10.1016/j.clnesp.2025.06.017","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Fermented soy foods come in different forms, each with varying effects on mortality. However, few epidemiological studies have investigated the effect of intake of individual types of fermented soy products on mortality. The present study aimed to investigate the association between intake of fermented soybeans, ‘natto,’ and all-cause mortality in community-dwelling elderly men, with a follow-up duration of approximately 15 years.</div></div><div><h3>Methods</h3><div>This prospective cohort study included 2174 men aged ≥65 years, of whom 2012 completed the baseline survey. Follow-up surveys were conducted five and 10 years later with mortality as the outcome. Participants completed a questionnaire regarding dairy natto intake. Hazard ratios (HRs) were calculated for the association between natto intake and all-cause mortality using Cox proportional hazards models.</div></div><div><h3>Results</h3><div>The final analysis population consisted of 1548 men. During a mean follow-up period of 12.0 years (18553.3 person-years), 430 deaths were identified. Compared with ‘no consumption’ of natto, HRs for ‘several packs/week’ and ‘pack/day or more’ were 0.603 (95 % confidence interval (CI) 0.441 to 0.825) and 0.786 (95 % CI 0.539 to 1.145), respectively. Compared with the category “No consumption at both baseline and first follow-up,” the HR for the category “Combination of several packs/week and one pack/day at baseline and first follow-up or several packs/week at both baseline and first follow-up” was 0.700 (95 % CI 0.507 to 0.966).</div></div><div><h3>Conclusions</h3><div>Habitual high intake of natto, especially over a long term, was associated with a lower risk of all-cause mortality in elderly men.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Pages 699-706"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative glycemic control in head and neck surgery","authors":"Sara Kring Nielsen ,&nbsp;Josefine Qvortrup Olsen ,&nbsp;Mahsa Jalili ,&nbsp;Irene Wessel ,&nbsp;Jens Rikardt Andersen","doi":"10.1016/j.clnesp.2025.06.024","DOIUrl":"10.1016/j.clnesp.2025.06.024","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>This study aimed to investigate the consequences of pre-operative dexamethasone administered to prevent post-operative pain and nausea on post-operative glycemic control and its influence on recovery.</div></div><div><h3>Methods</h3><div>A randomized controlled trial was conducted with hospitalized head and neck surgery patients receiving glucocorticoid premedication. Participants were randomized into intervention and control groups, and blood glucose was continuously monitored using the Freestyle Libre system. For hyperglycemia, insulin was administered per protocol in the intervention group but not in the control group. Secondary outcomes included muscle function, hydration, and recovery assessments.</div></div><div><h3>Results</h3><div>In 26 patients (21 % dropout rate), hyperglycemia (blood glucose (BG) ≥10 mmol/L) was observed in 54 % of patients. BG was correlated with age and duration of surgery, but normalized by small doses of rapid-acting insulin. Elevated p-C-peptide levels were associated with hyperglycemia. No significant differences between groups were found in maximum blood glucose, hospital stay, or readmissions. The intervention group showed significant muscle loss and poorer swallowing function but maintained functional ability in sit-to-stand tests.</div></div><div><h3>Conclusions</h3><div>Postoperative hyperglycemia was common during head and neck surgery, but was normalized by small doses of insulin despite the indications of postoperative insulin resistance. The intervention was never activated, as the problems with postoperative insulin resistance were minor and less than expected despite the administration of preoperative dexamethasone. Accordingly, standard protocols do not seem indicated in the postoperative care of these patients, but frequent measurements of blood glucose are recommended.</div></div><div><h3>Clinical Trials registration</h3><div>NCT04021186.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Pages 691-698"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional intake and diet quality over three years following liver transplantation","authors":"Amal Trigui ,&nbsp;Crystèle Hogue ,&nbsp;Mélanie Tremblay ,&nbsp;Geneviève Huard ,&nbsp;Christopher F. Rose ,&nbsp;Chantal Bémeur","doi":"10.1016/j.clnesp.2025.06.026","DOIUrl":"10.1016/j.clnesp.2025.06.026","url":null,"abstract":"<div><div>Recipients of liver transplantation (LT) are at high risk of malnutrition, sarcopenia and cardiovascular disease, yet no long-term dietary guideline after LT exists. This study aims to describe the nutritional intake and diet quality of LT recipients at 1-, 2-, and 3-years post-transplantation.</div></div><div><h3>Methods</h3><div>This cross-sectional study included adult patients with previous cirrhosis who underwent LT, divided into three cohorts: Cohort A (1-year post-LT), cohort B (2-years post-LT) and cohort C (3-years post-LT). Dietary intakes were assessed using the web-based 24 h dietary recall (R24W) and compared to the Acceptable Macronutrient Distribution Ranges (AMDR) and micronutrient reference values for the general population. Adherence to the Mediterranean diet and to the Canada's Food Guide were assessed using the Mediterranean (MED) score and the Healthy Eating Food Index (HEFI)-2019, respectively.</div></div><div><h3>Results</h3><div>Sixty-two LT recipients (62.9 % male) were included in this study: Cohort A (n = 23), cohort B (n = 14) and cohort C (n = 25). No significant differences were found between cohorts A, B and C in terms of intake of energy (2436.0; 2097.5; 1847.0 kcal), protein (90.3; 75.2; 85.6 g), carbohydrate (267.6; 269.1; 227.4 g) and total fat (95.3; 74.9; 70.7 g), respectively. Total fat intake was at the upper limit of the AMDR across all cohorts. Compared to males, females showed lower adherence to the AMDR of carbohydrate and to the recommended intakes for iron and calcium (p = 0.036; 0.004; and 0.002; respectively). Fiber and vitamins A, D and E intakes were below recommended levels, while sodium exceeded the recommended level for both sexes. Adherence to the Mediterranean diet (score 18.0/44) and Canada's Food Guide (score 39.0/80) was relatively low.</div></div><div><h3>Conclusions</h3><div>Nutritional intakes and diet quality indices in LT recipient remained unchanged across the three years post-LT, with significant deficiencies in certain micronutrients. Macronutrients intake could be optimized to better meet the specific needs of this population. Tailored dietary guidelines are needed for LT recipients, after the early phase post-surgery.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Pages 669-678"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct associations of type 1 and type 2 diabetes with osteoporosis and limitations of bone mineral density-based fracture risk prediction","authors":"Chi-Yuan Li,&nbsp;Chien-Hsiao Su,&nbsp;Heng-Wei Lin,&nbsp;Wei-Chih Kan,&nbsp;Chih-Chung Shiao","doi":"10.1016/j.clnesp.2025.06.022","DOIUrl":"10.1016/j.clnesp.2025.06.022","url":null,"abstract":"","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Pages 628-629"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal and neonatal vitamin D levels and hyperbilirubinemia: A systematic review and meta-analysis","authors":"Arezoo Ghavi ,&nbsp;Kathleen L. Meert ,&nbsp;Mohammad Asghari-Jafarabadi ,&nbsp;Rebecca Hill Renirie ,&nbsp;Zahra Mohammadi-Pirouz","doi":"10.1016/j.clnesp.2025.06.030","DOIUrl":"10.1016/j.clnesp.2025.06.030","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Vitamin D (Vit D) deficiency during pregnancy may have potential adverse effects on the health of mothers and neonates. The relationship between Vit D deficiency and neonatal hyperbilirubinemia is unknown. The aim of this study is to determine the relationship between Vit D levels in mothers and neonates and the occurrence of neonatal hyperbilirubinemia.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis were guided by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A literature search was conducted in electronic databases: PubMed, Cochrane, CINAHL, Scopus, Web of Science, Ovid MEDLINE, and MEDLINE Ultimate until the end of 2024 to find studies published in English that investigated Vit D levels in mothers or neonates and their associations with hyperbilirubinemia. The Newcastle Ottawa Scale (NOS) tool was used to assess the quality of the articles included. A random effects model was used for (subgroup) meta-analyses, assessing heterogeneity with I-squared, publication bias with funnel plot, Egger and Begg tests, and conducting meta-regression to explore heterogeneity sources.</div></div><div><h3>Results</h3><div>Of the 29 studies included in this systematic review, 25 were eligible for meta-analysis. Despite the overall lack of significant results in some aspects of this meta-analysis, the random-effects model showed that Vit D levels were significantly lower during pregnancy in mothers of neonates with hyperbilirubinemia compared to mothers of neonates without hyperbilirubinemia (MD: −7.98 nmol/L, 95%CI: −11.02 to −4.94, I2: 49.82 %, p &lt; 0.001). Additionally, Vit D levels were significantly lower in neonates with hyperbilirubinemia compared to neonates without hyperbilirubinemia (MD: −19.53 nmol/L, 95%CI: −25.42 to −13.64, I2: 93.76 %, p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>This review suggests that higher maternal Vit D levels during pregnancy may lead to higher Vit D levels in neonates and ultimately a lower risk of neonatal hyperbilirubinemia.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"68 ","pages":"Pages 715-726"},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}