Shiva Sareh, Zohreh Habibi, Mohammad Vasei, Moeinadin Safavi, Alieh Safari Sharari, Neda Pak, Golazin Shahbodagh khan, Mahmoudreza Ashrafi, Morteza Heidari
{"title":"Primary Diffuse Leptomeningeal Melanomatosis Leading to Raised Intracranial Pressure in a Pediatric Patient","authors":"Shiva Sareh, Zohreh Habibi, Mohammad Vasei, Moeinadin Safavi, Alieh Safari Sharari, Neda Pak, Golazin Shahbodagh khan, Mahmoudreza Ashrafi, Morteza Heidari","doi":"10.1002/ccr3.9705","DOIUrl":"10.1002/ccr3.9705","url":null,"abstract":"<p>A critical clinical consideration, in addition to other common risk factors predisposing individuals to idiopathic intracranial hypertension (IIH), involves the potential co-occurrence of increased intracranial pressure and elevated cerebrospinal fluid protein levels in the presence of underlying malignancies. Primary diffuse leptomeningeal melanomatosis, an exceptionally rare condition with few reported cases in the pediatric population, illustrates this scenario. Timely decision-making based on clinical suspicion to perform a biopsy and involving a skilled pathologist for accurate reporting are essential steps toward achieving a definitive diagnosis.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11769965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thamir Hashim, Yavuz Yigit, Khalid Yasir Fadul, Mostafa Dayraki, Ashraf Elmalik, Baha Hamdi Alkahlout, Aftab Mohammad
{"title":"Unusual presentation of medication-induced atrial fibrillation: A case report","authors":"Thamir Hashim, Yavuz Yigit, Khalid Yasir Fadul, Mostafa Dayraki, Ashraf Elmalik, Baha Hamdi Alkahlout, Aftab Mohammad","doi":"10.1002/ccr3.9204","DOIUrl":"10.1002/ccr3.9204","url":null,"abstract":"<p>This case highlights that atrial fibrillation can occur as an adverse effect of tamsulosin even in younger patients at lower doses, challenging the conventional understanding that this complication primarily affects older individuals on higher doses. Clinicians should remain vigilant for this potential side effect across all patient demographics to ensure prompt identification and management.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11769961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Detection and One-Year Follow-Up of Subclavian Steal Syndrome Treated With Traditional Chinese Medicine: A Case Report","authors":"Wen-Chieh Yang","doi":"10.1002/ccr3.70147","DOIUrl":"10.1002/ccr3.70147","url":null,"abstract":"<p>Subclavian steal syndrome (SSS) often goes undiagnosed because of its variable and subtle symptoms, highlighting the need for innovative diagnostic approaches. This case report explores the integration of traditional Chinese medicine (TCM) in both diagnosing and managing SSS, marking a pioneering contribution to the field. An 80-year-old woman with persistent dizziness, unresponsive to conventional treatments, underwent TCM pulse diagnosis, which revealed significant inter-arm pulse discrepancies. Subsequent Western imaging confirmed SSS. The patient was treated with Chinese herbal medicines (CHMs) targeting Qi deficiency and blood stasis, resulting in significant symptom improvement and a reduction in inter-arm systolic blood pressure disparities. Follow-up over 1 year showed sustained benefits. The integration of TCM pulse diagnosis, CHMs, and Western imaging highlights their complementary roles and potential as adjunctive therapies for managing SSS, offering a novel and comprehensive therapeutic strategy.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11761398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Ayurvedic Management of Fungal Sinusitis in Standalone Settings: A Case Report","authors":"Rajanikant Patel, Lakshmanan Skanthesh, Vishal Zaveri, Vinayak Padikkal, Oriparambil Sivaraman Nirmal Ghosh","doi":"10.1002/ccr3.70068","DOIUrl":"10.1002/ccr3.70068","url":null,"abstract":"<p>A 42-year-old female with left nasal blockage, facial numbness, upper palate pain, and headache was diagnosed with fungal ball sinusitis via CT scan. Refusing surgery, she opted for Ayurveda. Comprehensive treatment led to complete symptom resolution and a clear CT scan at 3 months.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11761411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ravi Shukla, Mandira Shrestha, Chaitanya Darshan Bhattarai, Kiran Lamichhane, Paras Yadav, Debendra Tamatta
{"title":"Scrub Typhus Infection Precipitating Hemolysis in a Patient With G6PD Deficiency: A Case Report","authors":"Ravi Shukla, Mandira Shrestha, Chaitanya Darshan Bhattarai, Kiran Lamichhane, Paras Yadav, Debendra Tamatta","doi":"10.1002/ccr3.70142","DOIUrl":"10.1002/ccr3.70142","url":null,"abstract":"<p>Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a well-known red blood cell enzymopathy and a cause of intravascular hemolysis. This case report presents a child with underlying G6PD deficiency who experienced an acute episode of extensive intravascular hemolysis induced by a scrub typhus infection. The key takeaway from this report is that scrub typhus infection can trigger extensive hemolysis in patients with even “mild” G6PD deficiency, and normal G6PD levels found during the acute phase of hemolysis do not rule out the possibility of underlying G6PD deficiency.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11761397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah N. Larson, Trevor F. Killeen, Laura Bowman, Sruthi Shankar, Emily Stock, Lindsay Welton, James V. Harmon Jr.
{"title":"Hepatic Rupture in HELLP Syndrome: Report of Two Patients and a Review of Peripartum Surgical Care and Transfusion","authors":"Sarah N. Larson, Trevor F. Killeen, Laura Bowman, Sruthi Shankar, Emily Stock, Lindsay Welton, James V. Harmon Jr.","doi":"10.1002/ccr3.70059","DOIUrl":"10.1002/ccr3.70059","url":null,"abstract":"<p>Herein, we report the cases of two patients with hemolysis, elevated liver enzymes, and low platelets syndrome who underwent emergent Cesarean sections that were complicated by massive hemorrhage due to undiagnosed hepatic rupture. Intraoperative General Surgery team intervention, early activation of massive transfusion protocol, hemostatic resuscitation, and transfer to ICU resulted in the survival of both patients.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11761413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Rapparini, A. Pileri, S. Robuffo, C. Agostinelli, Michelangelo La Placa
{"title":"Cutaneous involvement in multiple myeloma. A rare entity","authors":"L. Rapparini, A. Pileri, S. Robuffo, C. Agostinelli, Michelangelo La Placa","doi":"10.1002/ccr3.9476","DOIUrl":"10.1002/ccr3.9476","url":null,"abstract":"<p>Cutaneous involvement in multiple myeloma is rare and may present as nodules mimicking other lymphoid neoplasms. It typically occurs late in the course of the disease and is associated with an aggressive clinical course and poor prognosis.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11761395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erisa Christopher Gombya, Alleluyah Kemigisa, Racheal Kirabo, Ritah Nantale, David Mukunya, Job Kuteesa
{"title":"Successful Penile Refashioning Plus Glans Reconstruction With a Buccal Mucosa Graft: A Case Report","authors":"Erisa Christopher Gombya, Alleluyah Kemigisa, Racheal Kirabo, Ritah Nantale, David Mukunya, Job Kuteesa","doi":"10.1002/ccr3.70145","DOIUrl":"10.1002/ccr3.70145","url":null,"abstract":"<p>Poorly performed circumcisions can lead to severe complications, including penile injury and psychological distress. We present the case of a 9-year-old male who suffered from glans amputation following a poorly performed circumcision. The patient underwent successful penile refashioning and glans reconstruction with a buccal mucosa graft. Our case highlights the importance of proper surgical training and expertise in managing circumcision-related complications, and the potential benefits of reconstructive surgery in restoring normal anatomy and function. The case report contributes to literature on penile reconstruction following circumcision-related injuries.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Cascade of Abscess, Fasciitis, and Obstruction: Rare Presentation of Perforated Appendicitis","authors":"Ramin Bozorgmehr, Nastaran Hossein Shiroudi, Fatemeh Bastan, Mehrsa Jalali, Nazanin Alibeik, Maryam Rashidian","doi":"10.1002/ccr3.70139","DOIUrl":"10.1002/ccr3.70139","url":null,"abstract":"<p>Fasciitis and abdominal abscess, followed by bowel obstruction could be the first manifestation of a silent perforated appendicitis. So, clinicians should evaluate the patient's complete clinical picture to prevent misdiagnoses and delays in care.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bassel Hamam, Sarah Saleh, Miled Yaacoub, Houssein Chebbo, Sarah Jalloul, Karam Karam, Rima Houmani
{"title":"Defying the Odds: A Case of Successfully Treated Harlequin Ichthyosis in Lebanon","authors":"Bassel Hamam, Sarah Saleh, Miled Yaacoub, Houssein Chebbo, Sarah Jalloul, Karam Karam, Rima Houmani","doi":"10.1002/ccr3.70111","DOIUrl":"10.1002/ccr3.70111","url":null,"abstract":"<p>Harlequin ichthyosis is a rare skin disorder affecting newborns characterized by a scaly skin, flexed limbs, ectropium, and eclabium. The overall incidence of HI is 1 in 300,000 births, with approximately only 200 cases reported worldwide. Some studies uncovered a TH17 immune skewing in patients with HI, which is also seen in psoriasis. We herein present a case of a newborn found to have harlequin ichthyosis, whom his mother is known to have psoriasis. The baby was treated with topical antibiotics and retinoid creams. The baby then exhibited smoother skin with less scaling and flatter fissures.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11752141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}