Clinical Case ReportsPub Date : 2025-03-20eCollection Date: 2025-03-01DOI: 10.1002/ccr3.70260
Hashim Salar, Khizer Masroor Anns, Musa Salar, Faheemullah Khan, Muhammad Aman, Uffan Zafar, Izaz Ahmad, Sundas Basharat, Rehana Murad, Khizar Salar, Shayan Sirat Maheen Anwar
{"title":"From Gut to Gray Matter: A Case Report of Posterior Reversible Encephalopathy Syndrome in a Pediatric Patient With Celiac Disease.","authors":"Hashim Salar, Khizer Masroor Anns, Musa Salar, Faheemullah Khan, Muhammad Aman, Uffan Zafar, Izaz Ahmad, Sundas Basharat, Rehana Murad, Khizar Salar, Shayan Sirat Maheen Anwar","doi":"10.1002/ccr3.70260","DOIUrl":"10.1002/ccr3.70260","url":null,"abstract":"<p><p>Posterior reversible encephalopathy syndrome (PRES) is a rare neurological condition characterized by vasogenic edema, primarily affecting the posterior cerebral hemispheres. Although typically reversible with prompt treatment, PRES can lead to severe complications if not recognized early. This report presents an unusual and fatal case of PRES in a pediatric patient with celiac disease, a combination that is rarely documented in medical literature. A 9-year-old child with a history of celiac disease and dermatitis herpetiformis presented to the Emergency Room with a two-month history of vomiting and loose stools, accompanied by a recent 20-min seizure. Initial examination revealed pallor, emaciation, drowsiness, and a generalized rash. The patient was tachycardic, hypertensive (blood pressure 150/100 mmHg), and had an oxygen saturation of 65%. Neurological examination showed a glasgow coma scale (GCS) score of 10/15, increased muscle tone, and heightened reflexes. CT and MRI scans revealed intraparenchymal and subarachnoid hemorrhages. Despite aggressive management including intubation, antihypertensive therapy, anticonvulsants, and broad-spectrum antibiotics, the patient's condition deteriorated rapidly. Complications included pneumoperitoneum and eventual cardiac arrest, leading to the patient's death. This case highlights the potential for severe, life-threatening complications of PRES in pediatric patients with underlying autoimmune conditions such as celiac disease. It underscores the importance of considering PRES in the differential diagnosis for children with celiac disease presenting with neurological symptoms, even in the absence of typical radiological findings. The case also illustrates the need for further research into the relationship between celiac disease and PRES to improve outcomes in similar cases.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":"e70260"},"PeriodicalIF":0.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2025-03-20eCollection Date: 2025-03-01DOI: 10.1002/ccr3.70313
Mohsen Shafiepour, Behnam Dalfardi, Ali Nemati, Sina Bakhshaei, Elahenaz Parsi Mood
{"title":"Massive Hemoptysis in a Patient With Eisenmenger Syndrome, Polysplenia and Transverse Liver.","authors":"Mohsen Shafiepour, Behnam Dalfardi, Ali Nemati, Sina Bakhshaei, Elahenaz Parsi Mood","doi":"10.1002/ccr3.70313","DOIUrl":"10.1002/ccr3.70313","url":null,"abstract":"<p><p>Hemoptysis is defined as blood-streaked sputum from the lower parts of the respiratory tract. Hemoptysis, even in small amounts, is a frightening and alarm sign for possible underlying conditions such as infections, pulmonary diseases, neoplastic conditions, cardiovascular alterations, vasculitis, traumatic events, hematological derangements, and iatrogenic or drug-induced events. The initial step in the evaluation of hemoptysis is to determine the source of bleeding. Herein, we report an unusual case of massive hemoptysis in a young patient with polysplenia and Pulmonary Artery Hypertension (PAH) in the setting of Eisenmenger syndrome. Chest radiography was suggestive of multiple lung opacities bilaterally. Chest Computed Tomography (CT) revealed a non-heterogeneous mass-like lesion measuring 4 × 5.2 × 5.6 cm in the superior segment of the inferior lobe of the left lung, concerning for an accessory spleen. The patient underwent Video bronchoscopy, which showed tracheomalacia and active bleeding in the left main bronchus. The bleeding was controlled by the Argon Plasma Coagulation (APC) technique. Bronchoalveolar lavage (BAL) was negative for acid-fast bacilli on staining and on culture. After stabilization, the patient was discharged home on medical management for PAH. On two-week follow-up, imaging revealed resolution of the pulmonary mass-like lesion. Our report highlights the importance of bronchoscopy in determining the bleeding source in patients with hemoptysis and managing it via the APC technique.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":"e70313"},"PeriodicalIF":0.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acalculous Cholecystitis: The Unexpected Mask of De Novo Heart Failure.","authors":"Mhd Baraa Habib, Maram Albandak, Mhd Husam Osman, Shahem Abbarh, Bisher Sawaf, Yaseen Alastal, Abdulrahman Arabi","doi":"10.1002/ccr3.70324","DOIUrl":"10.1002/ccr3.70324","url":null,"abstract":"<p><p>Acute acalculous cholecystitis refers to inflammation of the gallbladder without the presence of gallstones or obstruction of the cystic duct. Heart failure is recognized for causing congestive hepatopathy and can lead to gallbladder swelling, often challenging to distinguish from acalculous cholecystitis. Here, we present a case of a patient whose symptoms initially resembled acalculous cholecystitis but were instead caused by acute severe heart failure and cardiogenic shock. Maintaining a broad differential diagnosis, including decompensated heart failure, is essential when evaluating cases resembling acalculous cholecystitis.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":"e70324"},"PeriodicalIF":0.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2025-03-19eCollection Date: 2025-03-01DOI: 10.1002/ccr3.70321
Sacide S Ozgur, Yezin Shamoon, M Nasr Al Rayess, Sherif Elkattawy, Abdullah Ahmad, Rachel Abboud, Fayez Shamoon
{"title":"A Case of Takotsubo Cardiomyopathy and Posterior Reversible Encephalopathy Syndrome Following Methadone Withdrawal.","authors":"Sacide S Ozgur, Yezin Shamoon, M Nasr Al Rayess, Sherif Elkattawy, Abdullah Ahmad, Rachel Abboud, Fayez Shamoon","doi":"10.1002/ccr3.70321","DOIUrl":"10.1002/ccr3.70321","url":null,"abstract":"<p><p>Takotsubo Cardiomyopathy (TTC) and Posterior Reversible Encephalopathy Syndrome (PRES) are rare but reversible complications associated with catecholamine surges during methadone withdrawal. Prompt recognition of these stress-related syndromes in patients undergoing methadone withdrawal is essential.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":"e70321"},"PeriodicalIF":0.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kundan Kumar Yadav, Milan Pokhrel, Geeta Bashyal, Shankar Pokharel, Santoshi Pokharel Kunwar
{"title":"Type 2 Sialidosis: A Rare Autosomal Recessive Condition in a 13-Year-Old Male: A Case Report","authors":"Kundan Kumar Yadav, Milan Pokhrel, Geeta Bashyal, Shankar Pokharel, Santoshi Pokharel Kunwar","doi":"10.1002/ccr3.70331","DOIUrl":"https://doi.org/10.1002/ccr3.70331","url":null,"abstract":"<p>This report presents a 13-year-old male with abnormal body movements, generalized body weakness, and developmental regression who was further evaluated to conclude type 2 Sialidosis as the diagnosis. Genetic testing is key in diagnosing such rare conditions, and management is difficult, particularly in resource-limited settings.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70331","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143638676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed H. AbdElaziz, Meshal Alharbi, Maher O. Shahada, Roqia Abdoh, Radhwan Saleh Algabri, Ahmed Yaseen Alqutaibi
{"title":"Management of a Complex Crown-Root Fracture in a Single Appointment Through Root Canal Therapy and Rebonding","authors":"Mohammed H. AbdElaziz, Meshal Alharbi, Maher O. Shahada, Roqia Abdoh, Radhwan Saleh Algabri, Ahmed Yaseen Alqutaibi","doi":"10.1002/ccr3.70332","DOIUrl":"https://doi.org/10.1002/ccr3.70332","url":null,"abstract":"<p>A 10-year-old male presented with a mobile and fractured maxillary right central incisor following dental trauma. Clinical and radiographic examinations revealed a chisel-type crown-root fracture with supragingival labial and subgingival palatal extensions. A direct crown reattachment was planned, emphasizing biological width preservation. After removing the coronal fragment, endodontic treatment was performed using a rotary file system and was obturated with a bioceramic sealer. A fiber post was selected and integrated into the fractured fragment, which was reattached using resin cement. Additionally, a gingivectomy was performed to enhance margin visibility and restore biological width. The adjacent left central incisor was treated for an uncomplicated crown fracture using follow-up evaluations over 12 months revealed stable fragment reattachment, good periodontal health, and restored aesthetics and function. A custom mouthguard was provided to prevent future trauma. This case highlights the efficacy of a multidisciplinary approach combining endodontic, restorative, and periodontal techniques for managing crown-root fractures, achieving favorable long-term outcomes in pediatric patients.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70332","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143638674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ST-Segment Elevation Myocardial Infarction With Right Coronary Aneurysm Successfully Treated With a Drug-Coated Balloon-Only Strategy","authors":"Yu Sugawara","doi":"10.1002/ccr3.70333","DOIUrl":"https://doi.org/10.1002/ccr3.70333","url":null,"abstract":"<p>ST-segment elevation myocardial infarction (STEMI) with a coronary aneurysm is rare; therefore, its treatment approach remains not well established. This case suggests that drug-coated balloon angioplasty may be considered for STEMI patients with coronary aneurysms.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143638673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mucosal Fenestration Closure: A Case Report on Regenerative Therapeutic Strategies","authors":"Nabin Thapa, Bibek Kattel, Abhishek Kumar, Sajeev Shrestha","doi":"10.1002/ccr3.70334","DOIUrl":"https://doi.org/10.1002/ccr3.70334","url":null,"abstract":"<p>Mucosal fenestration, a condition that poses risks to dental integrity, requires effective management to prevent complications such as unwanted tooth loss. The integration of guided tissue regeneration (GTR), Platelet-rich fibrin (PRF), and bone grafts is an effective strategy for managing mucosal fenestration, ensuring optimal tissue regeneration and long-term success.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70334","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143638751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seyyede Zeinab Azimi, Fatemeh Sari Aslani, Mohammad Mahdi Parvizi, Mohammad Reza Namazi
{"title":"Association of Bullous Lichen Sclerosus and Morphea","authors":"Seyyede Zeinab Azimi, Fatemeh Sari Aslani, Mohammad Mahdi Parvizi, Mohammad Reza Namazi","doi":"10.1002/ccr3.70315","DOIUrl":"https://doi.org/10.1002/ccr3.70315","url":null,"abstract":"<p>Lichen sclerosus (LSc) is an inflammatory skin disease of unknown etiology. The coexistence of LSc and morphea in the same lesion is uncommon but exists. Also, there exist a few rare cases of bullous LSc–generalized morphea overlap syndrome.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143638671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Negative Video Head Impulse Test in Acute Vestibular Syndrome Does Not Exclude Vestibular Neuritis: Insights and Challenges in Diagnosis","authors":"Pavol Skacik, Stefan Sivak, Egon Kurca","doi":"10.1002/ccr3.70300","DOIUrl":"https://doi.org/10.1002/ccr3.70300","url":null,"abstract":"<p>Video Head Impulse Test (v-HIT) is a valuable tool for diagnosing acute and chronic vestibular disorders but may yield false negatives in acute vestibular neuritis. Clinical judgment remains paramount; integrating patient history, physical findings, and ancillary tests ensures accurate diagnosis, especially when v-HIT results conflict with the clinical picture and other diagnostic tools.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70300","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}