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Conjunctival Rhinosporidosis Mimicking Papilloma in an Ethiopian Child: A Rare Case Report 埃塞俄比亚儿童结膜鼻孢子虫病模拟乳头状瘤：一个罕见的病例报告
IF 0.6
Clinical Case Reports Pub Date : 2025-05-05 DOI: 10.1002/ccr3.70439
Seblewengel Maru Wubalem, Social Beyecaha Diro
{"title":"Conjunctival Rhinosporidosis Mimicking Papilloma in an Ethiopian Child: A Rare Case Report","authors":"Seblewengel Maru Wubalem,&nbsp;Social Beyecaha Diro","doi":"10.1002/ccr3.70439","DOIUrl":"https://doi.org/10.1002/ccr3.70439","url":null,"abstract":"<p>Rhinosporidiosis is a chronic granulomatous disease caused by Rhinosporidium seeberi, mainly affecting the nose and nasopharynx. We report a sporadic occurrence of conjunctival rhinosporidiosis that mimicked papilloma in a 10-year-old Ethiopian child. Rhinosporidiosis should be considered in the differential diagnosis of conjunctival lesions. Histopathology is necessary for a definitive diagnosis.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70439","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Aphakia Associated With a GJA8 Pathogenic Variant: A Case Report 先天性失语症与GJA8致病变异相关：1例报告
IF 0.6
Clinical Case Reports Pub Date : 2025-05-05 DOI: 10.1002/ccr3.70286
Sarah A. M. Lucas, Elena Franco, Hannah L. Scanga, Nathan L. Clark, Ken K. Nischal
{"title":"Congenital Aphakia Associated With a GJA8 Pathogenic Variant: A Case Report","authors":"Sarah A. M. Lucas,&nbsp;Elena Franco,&nbsp;Hannah L. Scanga,&nbsp;Nathan L. Clark,&nbsp;Ken K. Nischal","doi":"10.1002/ccr3.70286","DOIUrl":"https://doi.org/10.1002/ccr3.70286","url":null,"abstract":"<p>Congenital aphakia is a rare eye condition in which the lens fails to form properly. It is typically caused by pathogenic variants within the <i>FOXE3</i> or <i>HCCS</i> genes; however, it can also be associated with <i>GJA8</i> pathogenic variants. <i>GJA8</i> should be included in the genetic testing of patients with this condition.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70286","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Refractory Bleeding at the Duodenal Bulb Post-Trauma Using OTSC Combined With Interventional Embolization: A Case Report OTSC联合介入栓塞治疗十二指肠球部外伤后难治性出血1例
IF 0.6
Clinical Case Reports Pub Date : 2025-05-05 DOI: 10.1002/ccr3.70486
Qing Chen, Shifeng Shao
{"title":"Management of Refractory Bleeding at the Duodenal Bulb Post-Trauma Using OTSC Combined With Interventional Embolization: A Case Report","authors":"Qing Chen,&nbsp;Shifeng Shao","doi":"10.1002/ccr3.70486","DOIUrl":"https://doi.org/10.1002/ccr3.70486","url":null,"abstract":"<p>Multiple traumas can lead to acute gastrointestinal mucosal erosion or ulcers, typically presenting as upper gastrointestinal bleeding, while perforation occurs rarely. Rebleeding poses a serious threat to life. Standard treatments include endoscopic electrocoagulation, tissue adhesives, and titanium clips. We report a case of a 39-year-old woman with post-traumatic stress ulcer bleeding successfully managed using a combination of over-the-scope clip (OTSC) placement and interventional embolization. This case demonstrates the effectiveness of OTSC combined with embolization in controlling post-traumatic ulcer bleeding and preventing recurrence.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70486","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual Presentation of Facial Comedones 面部粉刺的不寻常表现
IF 0.6
Clinical Case Reports Pub Date : 2025-05-05 DOI: 10.1002/ccr3.70466
Lamis Elyamani, Nassiba Zerrouki, Nada Zizi
{"title":"Unusual Presentation of Facial Comedones","authors":"Lamis Elyamani,&nbsp;Nassiba Zerrouki,&nbsp;Nada Zizi","doi":"10.1002/ccr3.70466","DOIUrl":"https://doi.org/10.1002/ccr3.70466","url":null,"abstract":"<p>Not all facial comedonal lesions represent acne, nor are they always benign. A lack of response to standard acne treatments should prompt clinicians to reconsider the diagnosis and explore more serious conditions, such as <i>comedonal lupus erythematosus</i>, <i>folliculotropic lymphoma</i>, or <i>acneiform syphilis</i>. Recognizing these conditions can significantly impact patient management.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Child With Edematous Malnutrition-Modulated Diabetes Mellitus: An Uncommon Ailment With Unusual Presentation and Management—Case Report 儿童水肿性营养不良调节性糖尿病：一种罕见的疾病，不寻常的表现和治疗-个案报告
IF 0.6
Clinical Case Reports Pub Date : 2025-05-05 DOI: 10.1002/ccr3.70389
Alemu Bogale, Tamirat Toma
{"title":"A Child With Edematous Malnutrition-Modulated Diabetes Mellitus: An Uncommon Ailment With Unusual Presentation and Management—Case Report","authors":"Alemu Bogale,&nbsp;Tamirat Toma","doi":"10.1002/ccr3.70389","DOIUrl":"https://doi.org/10.1002/ccr3.70389","url":null,"abstract":"<p>The “double burden of malnutrition” refers to the simultaneous occurrence of undernutrition and overnutrition in the same population over the course of a lifetime. Both chronic undernutrition and obesity have been linked to diabetes mellitus (DM); the former is more prevalent in developing countries and can result in malnutrition-modulated diabetes mellitus (MMDM). This case study aimed to educate medical practitioners in developing and underdeveloped countries on how to treat diabetes mellitus and malnutrition. We came across a 10-year-old girl presented with signs and symptoms of edematous malnutrition and ketone resistant diabetes mellitus. Treated and discharged after spending 45 days in the hospital with higher dose of insulin, 2.8 IU/kg/day while Formula-75 malnutrition rehabilitation was implemented side to side. Lastly, we propose and conclude that efficient demand-based insulin management, and nutritional rehabilitation based on WHO malnutrition and diabetes diet guidelines for daily energy requirements are essential for MMDM. In our case, the weight gain that came from nutritional rehabilitation over time had no effect on the amount of insulin she needed, which defies current knowledge and necessitates further research.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70389","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diffuse Multifocal Intracranial Hemorrhage Following Alteplase Infusion: A Case Image Report 阿替普酶输注后弥漫性多灶性颅内出血1例图像报告
IF 0.6
Clinical Case Reports Pub Date : 2025-05-05 DOI: 10.1002/ccr3.70263
Abdallah Alwali, Mohanad Faisal, Naveed Akhtar
{"title":"Diffuse Multifocal Intracranial Hemorrhage Following Alteplase Infusion: A Case Image Report","authors":"Abdallah Alwali,&nbsp;Mohanad Faisal,&nbsp;Naveed Akhtar","doi":"10.1002/ccr3.70263","DOIUrl":"https://doi.org/10.1002/ccr3.70263","url":null,"abstract":"<p>Hemorrhage beyond the ischemic area is an uncommon but serious complication of thrombolysis. This case underscores the importance of timely recognition of atypical bleeding sites, careful monitoring, and strict blood pressure control to improve outcomes in ischemic stroke patients post-thrombolysis.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70263","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143909301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Budd–Chiari Syndrome in a Young Female 一例罕见的年轻女性Budd-Chiari综合征
IF 0.6
Clinical Case Reports Pub Date : 2025-05-04 DOI: 10.1002/ccr3.70478
Joshua Chacko, Raymond Haward, Newton Ashish Shah, Saravenensandeep V. Pathmanathan, Bharath Sundaramoorthy, Jyothi Halepalya Tukaram
{"title":"A Rare Case of Budd–Chiari Syndrome in a Young Female","authors":"Joshua Chacko,&nbsp;Raymond Haward,&nbsp;Newton Ashish Shah,&nbsp;Saravenensandeep V. Pathmanathan,&nbsp;Bharath Sundaramoorthy,&nbsp;Jyothi Halepalya Tukaram","doi":"10.1002/ccr3.70478","DOIUrl":"https://doi.org/10.1002/ccr3.70478","url":null,"abstract":"<p>Budd–Chiari syndrome is a rare disorder characterized by hepatic vein obstruction, with an incidence of 1 in 100,000. It can be diagnosed through imaging studies and initially managed with anticoagulants. Acute Budd–Chiari syndrome can be treated with thrombolysis to dissolve blood clots obstructing hepatic veins. Venous obstructions in Budd–Chiari syndrome can be fixed through angioplasty or venous stenting to restore blood flow. Liver decompression can be achieved with TIPS, and severe cases may require liver transplantation.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70478","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Managing Internal Inflammatory Root Resorption and Perforation of a Mandibular Primary Molar: A Case Report With 15 Months Follow-Up 治疗内炎根吸收和下颌第一磨牙穿孔：1例随访15个月
IF 0.6
Clinical Case Reports Pub Date : 2025-05-04 DOI: 10.1002/ccr3.70475
Mana Mowji, Motahareh Khosrojerdi
{"title":"Managing Internal Inflammatory Root Resorption and Perforation of a Mandibular Primary Molar: A Case Report With 15 Months Follow-Up","authors":"Mana Mowji,&nbsp;Motahareh Khosrojerdi","doi":"10.1002/ccr3.70475","DOIUrl":"https://doi.org/10.1002/ccr3.70475","url":null,"abstract":"<p>In the present case, calcium-enriched mixture (CEM) cement demonstrated an excellent ability to impede internal inflammatory root resorption in a second primary molar with poor prognosis of a 5-year-old boy with an extremely immature apex.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70475","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Constrictive Pericarditis as a Rare Manifestation of Graft-Versus-Host Disease: A Case Report 缩窄性心包炎是移植物抗宿主病的一种罕见表现：1例报告
IF 0.6
Clinical Case Reports Pub Date : 2025-05-02 DOI: 10.1002/ccr3.70479
Alireza Arzhangzadeh, Mahmood Zamirian, Ladan Nasermoadeli, Asma Mousavi, Salma Nozhat, Roozbeh Narimani Javid, Sasan Shafiei, Salar Azadnik, Shayan Shojaei
{"title":"Constrictive Pericarditis as a Rare Manifestation of Graft-Versus-Host Disease: A Case Report","authors":"Alireza Arzhangzadeh,&nbsp;Mahmood Zamirian,&nbsp;Ladan Nasermoadeli,&nbsp;Asma Mousavi,&nbsp;Salma Nozhat,&nbsp;Roozbeh Narimani Javid,&nbsp;Sasan Shafiei,&nbsp;Salar Azadnik,&nbsp;Shayan Shojaei","doi":"10.1002/ccr3.70479","DOIUrl":"https://doi.org/10.1002/ccr3.70479","url":null,"abstract":"<p>Graft-versus-host disease (GVHD) is a serious inflammatory complication that can arise after allogeneic transplantation, characterized by donor T-cells attacking the recipient's tissues. While cardiac complications are infrequent, they are more commonly observed in cases of chronic GVHD and may manifest as pericardial effusion, cardiac tamponade, and various arrhythmias. Additionally, chronic GVHD can result in constrictive pericarditis (CP) due to the accumulation of fluid and scarring. A 25-year-old Iranian man developed CP 14 years after undergoing allogenic stem cell transplantation. Following inadequate response to medical therapy, he underwent a pericardiectomy. Pathological examination during follow-up revealed fibrosis and mild chronic inflammation. This report aims to add another case of cardiac manifestation associated with GVHD to the current literature. The main message emphasizes the urgent need for prompt diagnosis and effective pericardiectomy, which can be life-saving. Surgical referral should always be an option, and post-operative immunomodulation is crucial.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70479","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The phenotypic spectrum of the Cornelia de Lange-like “Alazami-Yuan syndrome”: A case report of the 7th diagnosed individual and review of the literature 兰格样“Alazami-Yuan综合征”的表型谱：第7例确诊病例报告及文献复习
IF 0.6
Clinical Case Reports Pub Date : 2025-05-02 DOI: 10.1002/ccr3.9208
Annie Pappas, Mary Mooney, Katherine Kohnen, Joshua W. Owens, Wenying Zhang, Robert J. Hopkin, Amelle Shillington
{"title":"The phenotypic spectrum of the Cornelia de Lange-like “Alazami-Yuan syndrome”: A case report of the 7th diagnosed individual and review of the literature","authors":"Annie Pappas,&nbsp;Mary Mooney,&nbsp;Katherine Kohnen,&nbsp;Joshua W. Owens,&nbsp;Wenying Zhang,&nbsp;Robert J. Hopkin,&nbsp;Amelle Shillington","doi":"10.1002/ccr3.9208","DOIUrl":"https://doi.org/10.1002/ccr3.9208","url":null,"abstract":"<p>We present a 17-year-old female with a childhood clinical diagnosis of Cornelia de Lange Syndrome (CdLS), however later genetic testing identified compound heterozygous variants in <i>TAF6</i>, consistent with AYS. This case report adds to the phenotypic spectrum observed in AYS, and draws connections to transcriptional pathways between CdLS and AYS.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9208","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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