{"title":"Intestinal Obstruction Secondary to Strangulated Richter Type Obturator Hernia: A Case Report.","authors":"Suresh Maharjan, Samrat Shrestha, Deepika Rijal, Sabin Ghimire, Kiran Bishwakarma","doi":"10.1002/ccr3.71149","DOIUrl":"https://doi.org/10.1002/ccr3.71149","url":null,"abstract":"<p><p>Obturator hernia is a rare internal hernia causing significant mortality and morbidity in elderly age groups. Diagnosis of obturator hernia is challenging because of vague atypical presentations. This case report describes a woman in her late 80s who presented with colicky right lower abdominal pain, abdominal distension, and obstipation, diagnosed with a right obturator hernia, computed tomography (CT) scan. An elderly female presented with chief complaints of right lower abdominal pain and abdominal distension. On examination, the abdomen was distended with generalized tenderness and rebound tenderness. CECT abdomen and pelvis showed dilated small bowel loops with a transition point caused by herniation through the right obturator foramen. Emergency laparotomy revealed a right strangulated obturator hernia. Resection of the gangrenous ileal segment with ileo-ileal anastomosis and primary closure of the defect was done. Obturator hernia occurs through the obturator canal, which is mostly seen in elderly females. Obturator hernia usually presents as partial bowel obstruction because of a high frequency (41%-100%) of Richter's herniation of the small bowel into the obturator canal. Diagnosis can be delayed because of its nonspecific clinical presentation. CT scan is the most accurate and sensitive way to diagnose the obturator hernia. Obturator defects can be repaired by various methods including simple suture closure, closure of the obturator with adjacent tissue, and mesh placement during laparotomy. Obturator hernia is a rare abdominal hernia with delayed diagnosis because of vague atypical clinical presentation. Early diagnosis and prompt surgical treatment are essential to reduce morbidity and mortality.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":"e71149"},"PeriodicalIF":0.6,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subacute Diarrhea: A Rare Presentation of Anaplastic T-Cell Lymphoma.","authors":"Nivedita Singh, Prateek Jain, Julian Chung, Amrit Devkota, Amogh Verma","doi":"10.1002/ccr3.71133","DOIUrl":"https://doi.org/10.1002/ccr3.71133","url":null,"abstract":"<p><p>Enteropathy-associated T-cell lymphoma type II should be considered in older patients who present with subacute diarrhea, abdominal pain, and cytopenias-even in the absence of celiac disease. Its rapid progression to bowel perforation demands prompt recognition and a multidisciplinary approach to improve outcomes.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":"e71133"},"PeriodicalIF":0.6,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Generalized Brown Papules.","authors":"Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Prakriti Lamichhane","doi":"10.1002/ccr3.71117","DOIUrl":"https://doi.org/10.1002/ccr3.71117","url":null,"abstract":"<p><p>Eruptive syringomas are a rare benign adnexal tumor variant of syringoma with widespread distribution that often mimics other dermatoses. The case image highlights the importance of histopathology in diagnosing eruptive syringoma. Thus, awareness of this condition is essential not only for accurate diagnosis but also for the appropriate treatment.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":"e71117"},"PeriodicalIF":0.6,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ernest Kwame Adjepong-Tandoh, Yaw Boateng Mensah, Michael Yao Ntumy, James Edward Mensah
{"title":"Multidisciplinary Management of Bilateral Ureteric Obstruction and Forniceal Rupture in Twin Pregnancy: A Case Report","authors":"Ernest Kwame Adjepong-Tandoh, Yaw Boateng Mensah, Michael Yao Ntumy, James Edward Mensah","doi":"10.1002/ccr3.71163","DOIUrl":"https://doi.org/10.1002/ccr3.71163","url":null,"abstract":"<p>Forniceal rupture during twin pregnancy is rare and mimics other abdominal emergencies such as ureteric colic, appendicitis, and ruptured ectopic; therefore, diagnosis requires a high index of suspicion. A multidisciplinary approach involving obstetricians, urologists, radiologists, general surgeons, and individualized intervention is key to achieving good maternal and fetal outcomes.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low-Grade Fetal Adenocarcinoma of the Lung on 18F-FDG PET/CT","authors":"Honghong Liu, Hongwei Yang, Ruimin Wang","doi":"10.1002/ccr3.71143","DOIUrl":"https://doi.org/10.1002/ccr3.71143","url":null,"abstract":"<p>Fetal adenocarcinoma of the lung (FLAC) is extremely rare without specific common symptoms and is difficult to distinguish from other lung cancers just by clinical symptoms and traditional imaging. We reported a case of FLAC that underwent <sup>18</sup>F-FDG PET-CT examination and summarized the findings of it.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71143","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of Gaucher Disease Type 1 in a Resource-Limited Setting: A Pediatric Case Study","authors":"Bipesh Kumar Shah, Diwakar Koirala, Bivek Mishra, Ramesh Sapkota, Manjil Basnet","doi":"10.1002/ccr3.71100","DOIUrl":"https://doi.org/10.1002/ccr3.71100","url":null,"abstract":"<p>This case report depicts the management of an 8-year-old male with Gaucher Disease Type 1, manifesting as massive splenomegaly, anemia, and skeletal involvement in a resource-constrained environment. Treated with splenectomy due to the absence of enzyme replacement therapy, it underscores the necessity for enhanced therapeutic access and comprehensive care.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using the Fluorescence In Situ Hybridization in the Diagnosis of Trisomy 13 in a Male Newborn From Mali","authors":"Alassane Baneye Maiga, Oumar Samassekou, Cheick Oumar Sidibé, Oumou Traoré, Belco Maiga, Mahamadou Traoré, Cheick Oumar Guinto, Guida Landouré","doi":"10.1002/ccr3.71093","DOIUrl":"https://doi.org/10.1002/ccr3.71093","url":null,"abstract":"<p>This case report details the first confirmed diagnosis of Trisomy 13 (Patau syndrome) in Mali using Fluorescence In Situ Hybridization (FISH). The male newborn presented with multiple congenital anomalies, including polydactyly and micrognathia. The diagnosis expands the understanding of Trisomy 13 in Africa, highlighting the importance of genetic testing in resource-limited settings.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71093","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bloomy Rind Sign in Leptomeningeal Metastasis of Primary Lung Adenocarcinoma","authors":"Wenyuan Tao, Xinhua Chen, Xin Zhang, Lijuan Han","doi":"10.1002/ccr3.71151","DOIUrl":"https://doi.org/10.1002/ccr3.71151","url":null,"abstract":"<p>The bloomy rind sign, which appears as hyperintensities on FLAIR along the surface of the brainstem without gadolinium contrast enhancement, is a rare and early finding indicative of leptomeningeal metastasis in patients with lung adenocarcinoma, often associated with EGFR gene mutations.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First Report of RET Fusion-Positive Lung Adenocarcinoma With Miliary Intrapulmonary Metastases Responsive to Selpercatinib: A Case Report","authors":"Soichi Iwanaka, Tadashi Nishimura, Hajime Fujimoto, Daichi Morita, Hitoshi Kuru, Yasumasa Sakakura, Corina N. D'Alessandro-Gabazza, Taro Yasuma, Esteban C. Gabazza, Masahiro Naito, Hidenori Ibata, Tetsu Kobayashi","doi":"10.1002/ccr3.71011","DOIUrl":"https://doi.org/10.1002/ccr3.71011","url":null,"abstract":"<p>Lung cancer presenting with miliary lung metastases on chest computed tomography is associated with poor prognosis. Recent studies indicate that non-small cell lung cancer harboring driver gene mutations, including rearranged during transfection (<i>RET)</i> fusions, can manifest with miliary lung metastases. However, the efficacy of molecularly targeted therapies in <i>RET</i> fusion-positive non-small cell lung cancer with miliary dissemination remains unknown. Here, we report a case of a 45-year-old man with a right lower lobe lung nodule, bilateral miliary intrapulmonary metastases, extensive lymphadenopathy, and metastases to the left adrenal gland, liver, and multiple bones. Transbronchial needle aspiration confirmed lung adenocarcinoma, with <i>RET</i> fusion detected via gene panel testing. Treatment with selpercatinib resulted in a sustained partial response for over one year, providing the first clinical evidence supporting this targeted therapy in <i>RET</i> fusion-positive lung adenocarcinoma with miliary metastases.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Repeated Visits to a Woman With Suspected Worms Discharged From the Urethra—A Case Study","authors":"Shuqian Cai, Xiaoping Xu, Junchi Xue, Yifei Hu","doi":"10.1002/ccr3.71071","DOIUrl":"https://doi.org/10.1002/ccr3.71071","url":null,"abstract":"<p>A 58-year-old female presented with a 6-month history of recurrent “worms” found in her toilet, which she suspected originated from her urinary tract. Physical examination was unremarkable. Laboratory analysis revealed motile, blood-red worm-like organisms measuring 25–35 mm in length, initially suspected to be <i>Dioctophyma renale</i> larvae. However, parasitic screening tests were negative, and microscopic examination identified setae characteristic of oligochaetes. Further investigation revealed these organisms only appeared in the first-floor toilet. Subsequent sterile urine collection showed no recurrence, confirming environmental earthworm contamination rather than true parasitosis. This case highlights the importance of morphological evaluation and proper specimen collection in differentiating parasitic infections from environmental contaminants.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}