Clinical Case Reports最新文献_第3页

Anesthesia Management of Cold Agglutinin Disease in a Pregnant Patient: A Case Report

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Clinical Case Reports Pub Date : 2024-11-29 DOI: 10.1002/ccr3.9645

Jibran Ikram, Chase Jackson, Sabry Ayad

{"title":"Anesthesia Management of Cold Agglutinin Disease in a Pregnant Patient: A Case Report","authors":"Jibran Ikram, Chase Jackson, Sabry Ayad","doi":"10.1002/ccr3.9645","DOIUrl":"https://doi.org/10.1002/ccr3.9645","url":null,"abstract":"Cold agglutinin disease (CAD), a rare autoimmune hemolytic anemia (AIHA), is characterized by hemolysis triggered by activation of the classical complement pathway. AIHA is estimated to affect one in 100,000 people in the general population; however, its incidence in pregnant women is unclear due to the scarcity of published studies. Here, we present the case of a 37-year-old female (G2P1102) who presented for a repeat Cesarean section. Her peripartum course was complicated by anemia (hemoglobin 7.9 g/dL, hematocrit 29.4%) attributed to cold agglutinin disease, necessitating the transfusion of 20 units of blood during this pregnancy. She had been receiving prednisone 10 mg daily for anemia. Cold temperatures can trigger the activation of cold-reactive antibodies, leading to red blood cells agglutination (clumping together). Preventing hypothermia reduces the likelihood of cold-induced hemolysis, which is the primary therapeutic strategy for cold agglutinin disease. Anesthetic management for the cesarean section was accomplished via spinal anesthesia, complemented by pain control through bilateral transversus abdominis plane (TAP) blocks. This multidisciplinary approach facilitated effective pain management while considering the patient's underlying condition.","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 12","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9645","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concurrent Acute Myeloid Leukemia and Autoimmune Hemolytic Anemia: Management Challenges and Clinical Insights: A Rare Case Report

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Clinical Case Reports Pub Date : 2024-11-29 DOI: 10.1002/ccr3.9620

Mais Musleh, Qossay Alhusein

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Mucocutaneous Ulcerations and Pancytopenia Secondary to Methotrexate Toxicity in a Patient With Rheumatoid Arthritis: A Case Report

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Clinical Case Reports Pub Date : 2024-11-29 DOI: 10.1002/ccr3.9638

Thinley Dorji, Tshering Penjor, Sangay Tenzin, Tshering Pedon, Sangay Wangchuck, Sonam Yangchen

{"title":"Mucocutaneous Ulcerations and Pancytopenia Secondary to Methotrexate Toxicity in a Patient With Rheumatoid Arthritis: A Case Report","authors":"Thinley Dorji, Tshering Penjor, Sangay Tenzin, Tshering Pedon, Sangay Wangchuck, Sonam Yangchen","doi":"10.1002/ccr3.9638","DOIUrl":"https://doi.org/10.1002/ccr3.9638","url":null,"abstract":"Toxicity from methotrexate overdosing is life threatening condition that requires prompt recognition and early treatment. A 71-year-old man from rural Bhutan with diabetes mellitus had symmetrical small joint pain for 3 years associated with early morning stiffness. He was evaluated and diagnosed with seropositive rheumatoid arthritis in a hospital in neighbouring India. He was initiated on Methotrexate and Hydroxychloroquine. The patient had inadvertently taken Methotrexate 10 mg OD for 2 weeks. Following this, he developed painful ulcers on the lips preventing him from swallowing and ulcers around the corona on the penis. He also had intermittent fever with chills. On examination, he had fluid responsive hypotension and pancytopenia without bleeding manifestations. He was managed with intravenous folinic acid, subcutaneous granulocyte colony stimulating factor and intravenous cloxacillin. He had an uneventful recovery and methotrexate has been restarted following adequate patient education. Education of patient and family members is key in preventing medication errors. Early identification and timely management of methotrexate toxicity is key in preventing mortality.","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 12","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9638","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herpes Simplex Encephalitis Complicated With Vasculitis in a Young Male: A Case Report

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Clinical Case Reports Pub Date : 2024-11-29 DOI: 10.1002/ccr3.9603

Sebhatleab T. Mulate, Abel T. Tasamma, Estifanos B. Fole, Zablon M. Anbessie, Merchaye A. Mengesha, Raja T. Muleta

引用次数: 0

Q Fever Endocarditis: A Challenging Diagnosis in a Patient Referring Weight Loss and Anorexia, and With Granulomas in Gastric Biopsy Specimens

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Clinical Case Reports Pub Date : 2024-11-29 DOI: 10.1002/ccr3.9635

Ana Elena Lago-Rodriguez, Pablo Arturo Fraile-Ribot, Isabel Amengual-Antich, Francisco Gual-Capllonch, Mercedes Garcia-Gasalla

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A Rare Case of Primary Vulvar Diffuse Large B-Cell Lymphoma: A Case Report

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Clinical Case Reports Pub Date : 2024-11-27 DOI: 10.1002/ccr3.9568

M. Singh, S. Ngakhusi, A. Shrestha, P. Subedi, K. Khadka, H. P. Dhakal

引用次数: 0

Sympathetic Ophthalmia Following an Evisceration Surgery—A Case Report

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Clinical Case Reports Pub Date : 2024-11-27 DOI: 10.1002/ccr3.9626

Rahmah Javed, Saba Al-Khairy, Hamna Khan, Hamna Raheel, Abdul Moeed, Salim Surani

引用次数: 0

Reversible Cerebral Vasoconstriction Syndrome Following Blood Transfusion in a Patient With Chronic Anemia: A Case Report

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Clinical Case Reports Pub Date : 2024-11-27 DOI: 10.1002/ccr3.9618

Amogh Verma, Govind Sharma, Ajeet Singh, Harshit Gupta, Deependra Pratap Singh, Abhay M. Gaidhane, Mahalaqua Nazli Khatib, Ganesh Bushi, Sanjit Sah, Rodrigue Ndabashinze

{"title":"Reversible Cerebral Vasoconstriction Syndrome Following Blood Transfusion in a Patient With Chronic Anemia: A Case Report","authors":"Amogh Verma, Govind Sharma, Ajeet Singh, Harshit Gupta, Deependra Pratap Singh, Abhay M. Gaidhane, Mahalaqua Nazli Khatib, Ganesh Bushi, Sanjit Sah, Rodrigue Ndabashinze","doi":"10.1002/ccr3.9618","DOIUrl":"https://doi.org/10.1002/ccr3.9618","url":null,"abstract":"Reversible cerebral vasoconstriction syndrome (RCVS) is a rare neurological disorder characterized by transient constriction and dilation of cerebral arteries, leading to severe headaches and neurological deficits. This case report describes a 41-year-old woman with chronic anemia, acute chronic kidney disease, type 2 diabetes mellitus, and rheumatoid arthritis who developed RCVS following transfusion of packed red blood cells (PRBCs). She experienced sudden-onset seizures and a thunderclap headache 5 days post-transfusion. Diagnostic imaging, including computed tomography (CT) and magnetic resonance imaging (MRI), revealed the characteristic features of vasogenic edema. The patient was treated with blood pressure control and symptomatic relief for pain, resulting in gradual improvement. This case highlights the importance of recognizing RCVS as a potential complication of blood transfusions, particularly in patients with significant comorbidities. Understanding the possible mechanisms, including rapid hemoglobin correction, and the effects of residual plasma and storage lesions in transfused blood, is essential to prevent and manage this rare but serious condition.","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 12","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9618","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating the Needles: Unveiling the Risks of Acupuncture: A Case Report

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Clinical Case Reports Pub Date : 2024-11-27 DOI: 10.1002/ccr3.9637

Harkesh Arora, Dhiran Sivasubramanian, Sinduja Sivakumar, Sivaguha Yadunath, Sreekant Avula

{"title":"Navigating the Needles: Unveiling the Risks of Acupuncture: A Case Report","authors":"Harkesh Arora, Dhiran Sivasubramanian, Sinduja Sivakumar, Sivaguha Yadunath, Sreekant Avula","doi":"10.1002/ccr3.9637","DOIUrl":"https://doi.org/10.1002/ccr3.9637","url":null,"abstract":"Acupuncture, an increasingly popular alternative medical therapy, has heightened the demand for information on its safety profile. This is a case report involving a 28-year-old female who presented with intense right-sided chest pain and breathlessness after an acupuncture session where needles were inserted into her chest wall. The immediate medical evaluation revealed a tension pneumothorax with radiographic evidence of a mediastinal shift, compelling, urgent intervention via chest tube insertion. The patient's symptoms persisted for 2 days before the pneumothorax diminished, facilitating the removal of the chest tube. This case emphasizes the atypical presentation of pneumothorax after acupuncture, suggesting a delayed onset of symptoms possibly related to the size of the bronchopleural fistula formed by the acupuncture needle. While acupuncture-related adverse events are uncommon, serious life-threatening complications like tension pneumothorax underscore the necessity for rigorous safety standards. Amidst the growing popularity of acupuncture, this report urges healthcare professionals to be aware of and report such incidents for enhanced patient education and safety.Trial Registration: This is not an interventional study. We only reported the patient's findings from our database as a case report","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 12","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9637","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142748924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Co-Existing Non-Occlusive Splenic Vein and Superior Mesenteric Vein Thrombosis in an Acute Necrotic Pancreatitis Patient—A Case Report

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Clinical Case Reports Pub Date : 2024-11-27 DOI: 10.1002/ccr3.9643

Andreea Irina Ghiță, Arina Ilinca Gheorghe, Georgiana Elena Beteringhe, Andreea Ramona Treteanu, Mihai Radu Pahomeanu

引用次数: 0