Sharanya Kumar, Rahul Tuli, Abdulsattar Mohammed, Brandon Duong, Kelly Downey
{"title":"Prolonged Pre-Eruptive Phase of Herpes Zoster Ophthalmicus in Immunocompetent Athlete: A Case of Delayed Diagnosis and Management Challenges","authors":"Sharanya Kumar, Rahul Tuli, Abdulsattar Mohammed, Brandon Duong, Kelly Downey","doi":"10.1002/ccr3.70399","DOIUrl":"https://doi.org/10.1002/ccr3.70399","url":null,"abstract":"<p>Herpes zoster ophthalmicus should be considered in patients with intractable headache and eye pain, even without rash or classic risk factors. Early recognition of the pre-eruptive phase and prompt antiviral therapy are crucial to prevent severe complications, including permanent vision loss or blindness.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70399","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concurrent Pancreatic and Sartorius Muscle Lipomas: A Case Report","authors":"Om Prakash Bhattaa, Shritik Devkotab, Arun Kalikotec, Prakash Gyawalid, Sachin Awasthie","doi":"10.1002/ccr3.70350","DOIUrl":"https://doi.org/10.1002/ccr3.70350","url":null,"abstract":"<p>We present an incidentally diagnosed case of concurrent pancreatic and Sartorius muscle lipoma in a 65-year-old female with cholelithiasis. Such dual presentation has seldom been mentioned in the literature and requires thorough evaluation to differentiate it from other pathologies.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70350","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abraam Rezkalla, Ahmad Nouri, Fadi Hadya, Islam Rajab, Emile Doss
{"title":"Successful Aspiration Thrombectomy for Cocaine-Induced Right Coronary Artery Embolism Secondary to Left Ventricular Thrombus: A Case Report and Literature Review","authors":"Abraam Rezkalla, Ahmad Nouri, Fadi Hadya, Islam Rajab, Emile Doss","doi":"10.1002/ccr3.70432","DOIUrl":"https://doi.org/10.1002/ccr3.70432","url":null,"abstract":"<p>Coronary embolism (CE) is a rare yet significant contributor to acute myocardial infarction (AMI), particularly in younger patients. We report a 42-year-old male who experienced an AMI following recent cocaine use. Investigations revealed a left ventricular apical thrombus, identified as the source of a distal embolus occluding the right coronary artery (RCA). Cocaine is known for its thrombogenic effects, promoting thrombus formation through mechanisms such as vasoconstriction and increased platelet aggregation. This unique situation highlights the critical interplay between cocaine use, left ventricular thrombus formation, and the resultant coronary artery embolism, contributing to myocardial ischemia. The patient underwent successful aspiration thrombectomy, restoring coronary blood flow without the need for stenting. This case underscores the importance of recognizing CE as a potential etiology of AMI, particularly in the context of substance abuse, advocating for heightened awareness among clinicians regarding the complexities of managing thromboembolic events.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70432","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case Image: Cutaneous Leiomyoma","authors":"Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Prakriti Lamichhane","doi":"10.1002/ccr3.70471","DOIUrl":"https://doi.org/10.1002/ccr3.70471","url":null,"abstract":"<p>Cutaneous leiomyomas are rare benign smooth muscle tumors that often present as painful dermal nodules; however, they can be asymptomatic too. Histopathology remains the gold standard for diagnosis and warrants screening for Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) in patients presenting with multiple lesions.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70471","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Mohammadi-Asl, Amir Reza Bahadori, Iman Sabzgolin, Afshan Davari, Mohammad Razmafrooz, Abbas Tafakhori, Mehrdad Sheikhvatan, Sara Ranji
{"title":"Autoimmune Encephalitis and Musicogenic Epilepsy: A Case of GAD65 Antibody-Associated Seizure","authors":"Ali Mohammadi-Asl, Amir Reza Bahadori, Iman Sabzgolin, Afshan Davari, Mohammad Razmafrooz, Abbas Tafakhori, Mehrdad Sheikhvatan, Sara Ranji","doi":"10.1002/ccr3.70444","DOIUrl":"https://doi.org/10.1002/ccr3.70444","url":null,"abstract":"<p>Musicogenic epilepsy (ME) is a rare form of reflex epilepsy with a prevalence of 1 in 10,000,000. Recent research suggests a potential link between ME and autoimmune encephalitis, particularly involving glutamic acid decarboxylase 65-isoform (GAD65) antibodies. A 48-year-old female presented with a one-year history of music-triggered seizures. Her episodes were characterized by an initial aura followed by unresponsiveness and oral automatisms. Electroencephalography revealed abnormalities in the left anterior temporal lobe and temporal leads. Laboratory studies showed positive anti-GAD65 antibodies. The patient was treated with a combination of antiepileptic medication (Lamotrigine) and corticosteroids and intravenous immunoglobulin. This case contributes to the growing evidence supporting an association between ME and autoimmune mechanisms, particularly GAD65 antibody-mediated autoimmunity. It highlights the importance of screening autoimmune factors in ME patients and highlights the need for further research into targeted treatment strategies.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 5","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70444","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles John Nhungo, Doreen Gerion Gilbert, Boniface Nzowa, Philipo Felix, Nimwindael Msangi, Theoflo Mmbando, Gabriel Mtaturu, Obadia Nyongole, Charles A. Mkony
{"title":"Giant Adrenal Neuroblastoma in Adults: Surgical Management and Comprehensive Review","authors":"Charles John Nhungo, Doreen Gerion Gilbert, Boniface Nzowa, Philipo Felix, Nimwindael Msangi, Theoflo Mmbando, Gabriel Mtaturu, Obadia Nyongole, Charles A. Mkony","doi":"10.1002/ccr3.70453","DOIUrl":"https://doi.org/10.1002/ccr3.70453","url":null,"abstract":"<p>Neuroblastoma (NB) is a rare solid tumor of the sympathetic nervous system, primarily occurring in children and rarely in adults. Its extracranial origin stems from the medullary region of the adrenal gland or sympathetic ganglia. We report an 18-year-old female who presented with a 6-month history of abdominal swelling and tenderness. Imaging revealed a large retroperitoneal mass causing significant displacement of adjacent structures. Following multidisciplinary optimization, a huge tumor was successfully resected surgically. Histopathology confirmed the diagnosis of adrenal NB. The patient underwent adjuvant chemotherapy and remained symptom-free with favorable outcomes during a 9-month follow-up. This case underscores the importance of comprehensive diagnostic evaluation and multimodal management in treating rare adult adrenal NB.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70453","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring “Intoxicated Syndrome”: A rare case of cervical kyphoscoliosis due to drug abuse","authors":"Majid Rezvani, Seyedali Modarres Sadeghi, Farid Masaeli, Anish Thapa, Ashani Shah, Farhad Mahmoudi","doi":"10.1002/ccr3.9531","DOIUrl":"https://doi.org/10.1002/ccr3.9531","url":null,"abstract":"<p>Dropped head syndrome (DHS), marked by severe cervical muscle weakness, causes progressive kyphosis and difficulty in maintaining head posture. This case study reports on a 23-year-old male with DHS linked to drug abuse, underscoring the need to consider substance abuse as a cause and highlighting effective surgical treatment.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9531","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fifty-Four Tablets Too Many: A Case Report of Amlodipine and Losartan Overdose","authors":"Nishan Uprety, Bishal Bhandari, Vinayak Dhungana, Sulav Neupane, Sunischit Chandra Neupane, Sujan Tamang, Samiksha Acharya","doi":"10.1002/ccr3.70457","DOIUrl":"https://doi.org/10.1002/ccr3.70457","url":null,"abstract":"<p>Overdoses of widely used cardiovascular drugs calcium channel blockers and angiotensin receptor blockers cause severe hemodynamic instability. Timely management with hyperinsulinemia–euglycemia therapy, vasopressors, and calcium gluconate is critical. Enhanced clinical vigilance, prompt intervention, and long-term care, including psychological evaluation, are essential to address underlying factors and prevent recurrence of overdoses.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70457","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nasreldin A. Hamza, Wasfy J. Hamad, Shamim K. Vakkulathil, Vimalraj Sundaram, Haidar M. Hadi, Abdulqadir J. Nashwan
{"title":"To Lyse or Not: The Role of Half-Dose Thrombolysis in Right Ventricular Clot Associated With Sub-Massive Pulmonary Embolism","authors":"Nasreldin A. Hamza, Wasfy J. Hamad, Shamim K. Vakkulathil, Vimalraj Sundaram, Haidar M. Hadi, Abdulqadir J. Nashwan","doi":"10.1002/ccr3.70404","DOIUrl":"https://doi.org/10.1002/ccr3.70404","url":null,"abstract":"<p>Right heart thrombi are rare but carry a high mortality risk. Appropriate therapy remains unclear; options include anticoagulation, thrombolysis, and surgical thrombectomy. In this case, a 43-year-old male with DVT, RV thrombus, and bilateral pulmonary embolism responded well to half-dose thrombolytic therapy, with complete thrombus resolution and no complications.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70404","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Taib Fatih, Mohammed Abdalla Mahmood, Mohammed Khalid Mahmood, Amanj Ismael Tahir, Handren Ameer Kurda, Mohammed Aso Abdulghafor, Balen Hamid Qadir, Zana Fuad Noori
{"title":"Post-COVID-19 Exacerbation of a Stable Fibrous Dysplasia: A Case Report","authors":"Mohammed Taib Fatih, Mohammed Abdalla Mahmood, Mohammed Khalid Mahmood, Amanj Ismael Tahir, Handren Ameer Kurda, Mohammed Aso Abdulghafor, Balen Hamid Qadir, Zana Fuad Noori","doi":"10.1002/ccr3.70474","DOIUrl":"https://doi.org/10.1002/ccr3.70474","url":null,"abstract":"<p>Fibrous dysplasia (FD) is a rare, benign fibro-osseous lesion characterized by replacement of normal bone with extensive fibrous stroma due to abnormalities in osteoblast differentiation. After puberty and during adulthood, FD lesions usually become quiescent. However, some cases show signs of regrowth and reactivation. Here, we report a previously stable maxillary FD case in a 32-year-old man reactivated after a mild COVID-19 infection. We hypothesize that SARS-CoV-2 may utilize diverse mechanisms to induce tumor/cancer in multiple organs, including initiating inflammatory cascades and modifying tumor-suppressing pathways. The capacity of SARS-CoV-2 to enhance the expression of proinflammatory and tumorigenic molecules necessitates further research to ascertain any correlation between this viral infection and FD or other similar diseases.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70474","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}