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IgG4-Related Disease (IgG4-RD) Autoimmune Pancreatitis (AIP) as an Initial Presentation of Systemic Lupus Erythematosus (SLE) 作为系统性红斑狼疮（SLE）初期表现的 IgG4 相关疾病（IgG4-RD）自身免疫性胰腺炎（AIP）
IF 0.6
Clinical Case Reports Pub Date : 2025-04-04 DOI: 10.1002/ccr3.70163
Srilatha Kothandaraman, Rithwik Terala
{"title":"IgG4-Related Disease (IgG4-RD) Autoimmune Pancreatitis (AIP) as an Initial Presentation of Systemic Lupus Erythematosus (SLE)","authors":"Srilatha Kothandaraman,&nbsp;Rithwik Terala","doi":"10.1002/ccr3.70163","DOIUrl":"https://doi.org/10.1002/ccr3.70163","url":null,"abstract":"<p>Acute pancreatitis stemming from IgG4-Related Disease (IgG4-RD) seldom coincides with Systemic Lupus Erythematosus (SLE), highlighting the importance of investigating autoimmune conditions in patients with IgG4-RD. We present the case of a 57-year-old male with a medical history notable for hypertension, photosensitivity, arthritis, and malar rash, who presented with 6 weeks of persistent epigastric pain. Computed Tomography (CT) of the abdomen revealed hallmark features such as fat stranding around the pancreatic tail and gallbladder wall thickening, confirming the diagnosis of acute pancreatitis and cholecystitis. Post-cholecystectomy, histopathological examination of the gallbladder displayed IgG4-positive staining in multiple vessels, accompanied by perivascular inflammation and fibrinoid necrosis infiltrated by lymphocytes and neutrophils, confirming the diagnosis of IgG4-RD. Subsequent evaluation prompted by systemic manifestations revealed an ANA titer of 1:5120 and a dsDNA titer of 1:80, leading to the diagnosis of SLE. The patient later developed mononeuropathy, which improved upon initiation of immunosuppressive therapy. This case underscores the intricate interplay between IgG4-RD and SLE, an association documented to a limited extent in literature, thereby emphasizing the imperative of considering alternative autoimmune diseases with manifestations akin to IgG4-RD.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correcting Multiple Spaces in Adult Patients With Precise Tooth Movement Control Using In-House Clear Aligners 使用室内透明矫治器精确控制牙齿移动，矫正成年患者的多间隙问题
IF 0.6
Clinical Case Reports Pub Date : 2025-04-04 DOI: 10.1002/ccr3.70393
Nguyen Van Tam, Trieu Thi Phuong, Vu Thi Van Anh, Hoang Viet
{"title":"Correcting Multiple Spaces in Adult Patients With Precise Tooth Movement Control Using In-House Clear Aligners","authors":"Nguyen Van Tam,&nbsp;Trieu Thi Phuong,&nbsp;Vu Thi Van Anh,&nbsp;Hoang Viet","doi":"10.1002/ccr3.70393","DOIUrl":"https://doi.org/10.1002/ccr3.70393","url":null,"abstract":"<p>Diastema or spacing in the anterior teeth is one frequent complaint of patients for undergoing orthodontic treatment. This case report presents the treatment of an adult patient with multiple spacings in the anterior teeth due to a Bolton discrepancy that was treated mostly by tipping using clear aligners. After 16 months of treatment, the patient's profile improved (Upper incisor inclination U1-FH: decreased from 127° to 117.86°; lower incisor inclination IMPA: decreased from 103° to 96°; Upper lip to E-line: decreased from 1.81 to 0.25 mm, Lower lip to E-line: decreased from 1.74 to 1.25 mm). Clear aligners can effectively address spacing issues in the anterior teeth of adult patients who have high aesthetic demands.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70393","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leptomeningeal Seeding of Pituitary Adenoma in a Young Lady With Neglected Gigantism: An Extremely Rare Case Report
IF 0.6
Clinical Case Reports Pub Date : 2025-04-04 DOI: 10.1002/ccr3.70342
Sadegh Bagherzadeh, Milad Shafizadeh, Seyed Mohammad Tavangar, Alireza Khoshnevisan
{"title":"Leptomeningeal Seeding of Pituitary Adenoma in a Young Lady With Neglected Gigantism: An Extremely Rare Case Report","authors":"Sadegh Bagherzadeh,&nbsp;Milad Shafizadeh,&nbsp;Seyed Mohammad Tavangar,&nbsp;Alireza Khoshnevisan","doi":"10.1002/ccr3.70342","DOIUrl":"https://doi.org/10.1002/ccr3.70342","url":null,"abstract":"<p>Pituitary neuroendocrine tumors can sometimes present with leptomeningeal seeding at their initial diagnosis, emphasizing the need for thorough evaluation in cases of leptomeningeal involvement. Additionally, it is crucial for general physicians to inquire about a patient's menstrual status, particularly in low socioeconomic conditions, as this information can provide valuable insights into the hypothalamic–pituitary axis function.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of ACTH-Secreting Pituitary Adenoma in a Pediatric Patient. Diagnosis and Management: Case Report and Literature Review
IF 0.6
Clinical Case Reports Pub Date : 2025-04-04 DOI: 10.1002/ccr3.70385
Shadi Niliyeh, Fatemeh Sayarifard, Ali Moradi, Aria Setoodeh, Pouya Ebrahimi
{"title":"A Rare Case of ACTH-Secreting Pituitary Adenoma in a Pediatric Patient. Diagnosis and Management: Case Report and Literature Review","authors":"Shadi Niliyeh,&nbsp;Fatemeh Sayarifard,&nbsp;Ali Moradi,&nbsp;Aria Setoodeh,&nbsp;Pouya Ebrahimi","doi":"10.1002/ccr3.70385","DOIUrl":"https://doi.org/10.1002/ccr3.70385","url":null,"abstract":"<p>Due to its rare incidence, pituitary adenoma requires high vigilance and suspicion. Therefore, physicians should consider this differential diagnosis and perform the necessary workup, such as an overnight or standard dexamethasone suppression test and brain magnetic resonance imaging (MRI), to rule it out if sudden hormonal changes without any other explanation are observed in children.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70385","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Both Cardiac Myxoma and Left Coronary AVF, Diagnosis, and Management
IF 0.6
Clinical Case Reports Pub Date : 2025-04-04 DOI: 10.1002/ccr3.70380
Isa Khaheshi, Hamed Askarpour, Seyyed Amirhossein Salehi, Atoosa Gharib
{"title":"A Rare Case of Both Cardiac Myxoma and Left Coronary AVF, Diagnosis, and Management","authors":"Isa Khaheshi,&nbsp;Hamed Askarpour,&nbsp;Seyyed Amirhossein Salehi,&nbsp;Atoosa Gharib","doi":"10.1002/ccr3.70380","DOIUrl":"https://doi.org/10.1002/ccr3.70380","url":null,"abstract":"<p>We present the case of a 62-year-old woman who was diagnosed with both cardiac myxoma and left coronary AVF, and we go on to discuss the course of her treatment and the outcome. In conclusion, this case study highlights the rare coexistence of an atrial myxoma and a congenital coronary arteriovenous fistula in a 65-year-old woman. A thorough cardiovascular evaluation using echocardiography and advanced imaging facilitated accurate diagnosis and informed surgical planning. The surgical approach featured the simultaneous resection of the myxoma and direct repair of the fistula, effectively minimizing surgical risks. A 65-year-old female presented with complaints of chest pain and shortness of breath that were exacerbated by physical activity. The results of angiography confirmed that the mass in the left atrium was indeed an atrial myxoma. Additionally, the angiography revealed a congenital arteriovenous fistula (AVF) between the left coronary arteries and the left atrium, adding another layer of complexity to the patient's condition.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70380","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diffuse Large B-Cell Lymphoma With Membranous Proliferative Glomerulonephritis as the First Manifestation: A Case Report
IF 0.6
Clinical Case Reports Pub Date : 2025-04-03 DOI: 10.1002/ccr3.70353
Hongrui Xiao, Lei Ye, Fenjuan Zhang
{"title":"Diffuse Large B-Cell Lymphoma With Membranous Proliferative Glomerulonephritis as the First Manifestation: A Case Report","authors":"Hongrui Xiao,&nbsp;Lei Ye,&nbsp;Fenjuan Zhang","doi":"10.1002/ccr3.70353","DOIUrl":"https://doi.org/10.1002/ccr3.70353","url":null,"abstract":"<p>Clinicians should investigate the causes of kidney disease in patients with poor therapeutic effects. Lymphoma should be considered in patients with renal damage combined with anemia, elevated globulin, elevated immunoglobulin, and lymphadenopathy. Promptly perform renal biopsy, lymph node biopsy, and blood and bone marrow specimen examination to avoid misdiagnosis and delayed treatment.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70353","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delay in Diagnosis of a Rare Case of Microcystic Adnexal Carcinoma in a Middle-Aged Woman
IF 0.6
Clinical Case Reports Pub Date : 2025-04-03 DOI: 10.1002/ccr3.70392
Saman Al-Zahawi, Neda Serkani, Vahideh Sadat Azhari, Zahra Razavi, Kamran Balighi, Fatemeh Saberi
{"title":"Delay in Diagnosis of a Rare Case of Microcystic Adnexal Carcinoma in a Middle-Aged Woman","authors":"Saman Al-Zahawi,&nbsp;Neda Serkani,&nbsp;Vahideh Sadat Azhari,&nbsp;Zahra Razavi,&nbsp;Kamran Balighi,&nbsp;Fatemeh Saberi","doi":"10.1002/ccr3.70392","DOIUrl":"https://doi.org/10.1002/ccr3.70392","url":null,"abstract":"<p>MAC is a rare adnexal tumor with nonspecific clinical presentation. Dermatologists should consider the diagnosis of MAC when there is a solitary, longstanding lesion with aberrant clinical behavior supported by typical pathological findings of sweat gland malignant changes.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70392","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Music Therapy and Pharmacotherapy as a Combination Treatment: A Case of Periodic Depression in Comorbidity With Subthreshold Autism
IF 0.6
Clinical Case Reports Pub Date : 2025-04-03 DOI: 10.1002/ccr3.70229
Helle Nystrup Lund, Antonio Drago
{"title":"Music Therapy and Pharmacotherapy as a Combination Treatment: A Case of Periodic Depression in Comorbidity With Subthreshold Autism","authors":"Helle Nystrup Lund,&nbsp;Antonio Drago","doi":"10.1002/ccr3.70229","DOIUrl":"https://doi.org/10.1002/ccr3.70229","url":null,"abstract":"<p>Subthreshold Autism Spectrum Disorder (ASD) can complicate depression treatment as ASD may hinder treatment benefits. In this case, a patient in treatment for recurring depression with traits of ASD showed symptom reduction, improved relational functioning, and emotion regulation skills by combining pharmacotherapy and music therapy.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70229","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left Bundle Branch Pacing in a Patient With Dextroposed Heart: A Case Report
IF 0.6
Clinical Case Reports Pub Date : 2025-04-03 DOI: 10.1002/ccr3.70284
Dilip Kumar, Amit Malviya, Rabin Chakraborty, Ashesh Halder, Subhro Sekhar Chakraborty, Anand Kumar Pandey, Pinak Pani Das, Rinchin Dorjee Meegeji
{"title":"Left Bundle Branch Pacing in a Patient With Dextroposed Heart: A Case Report","authors":"Dilip Kumar,&nbsp;Amit Malviya,&nbsp;Rabin Chakraborty,&nbsp;Ashesh Halder,&nbsp;Subhro Sekhar Chakraborty,&nbsp;Anand Kumar Pandey,&nbsp;Pinak Pani Das,&nbsp;Rinchin Dorjee Meegeji","doi":"10.1002/ccr3.70284","DOIUrl":"https://doi.org/10.1002/ccr3.70284","url":null,"abstract":"<p>The Right Ventricular (RV) apex has been the standard site for pacing in symptomatic bradyarrhythmias, but chronic RV pacing can cause adverse effects such as atrial arrhythmias and left ventricular dysfunction. Physiological pacing, including His bundle and left bundle pacing, offers alternatives with fewer complications. We present a 66-year-old male with a dextroposed heart and fibrotic right lung requiring left bundle branch pacing due to a high RV pacing burden. The procedure involved modified lead placement and a medial subclavian vein puncture, successfully achieving good electrical parameters and post-procedural device function, highlighting left bundle branch pacing's feasibility in complex anatomical conditions.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70284","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Longstanding Case of Black Grain Mycetoma in a Somalian Male Patient: A Case Report
IF 0.6
Clinical Case Reports Pub Date : 2025-04-03 DOI: 10.1002/ccr3.70394
Mohamed Adam Mahamud, Mohamed Daffalla Awadalla Gismalla, Shafie Abdulkadir Hassan, Alaa Tajeldeen Habeeb Abdallah, Claude Mambo Muvunyi, Ayman Ahmed, Emmanuel Edwar Siddig
{"title":"A Longstanding Case of Black Grain Mycetoma in a Somalian Male Patient: A Case Report","authors":"Mohamed Adam Mahamud,&nbsp;Mohamed Daffalla Awadalla Gismalla,&nbsp;Shafie Abdulkadir Hassan,&nbsp;Alaa Tajeldeen Habeeb Abdallah,&nbsp;Claude Mambo Muvunyi,&nbsp;Ayman Ahmed,&nbsp;Emmanuel Edwar Siddig","doi":"10.1002/ccr3.70394","DOIUrl":"https://doi.org/10.1002/ccr3.70394","url":null,"abstract":"<p>Mycetoma is a chronic granulomatous infection predominantly affecting young individuals, characterized by painless swelling and often misdiagnosed due to its resemblance to other conditions. This case report presents the first documented instance of eumycetoma located in the buttock of a 44-year-old male patient from Somalia, a region with limited literature on this disease. The patient exhibited a 10-year history of indurated swelling, which progressed to the discharge of dark granules, leading to the diagnosis of black grain eumycetoma. Comprehensive diagnostic methods, including imaging and histopathological analysis, were used, confirming the fungal etiology. Surgical excision followed, alongside antifungal therapy, resulting in significant improvement. This case emphasizes the necessity for increased awareness and consideration of mycetoma in clinical practice, especially in atypical presentations and underreported geographical areas.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70394","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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