{"title":"原发性肺腺癌轻脑膜转移的Bloomy Rind征象","authors":"Wenyuan Tao, Xinhua Chen, Xin Zhang, Lijuan Han","doi":"10.1002/ccr3.71151","DOIUrl":null,"url":null,"abstract":"<p>The bloomy rind sign, which appears as hyperintensities on FLAIR along the surface of the brainstem without gadolinium contrast enhancement, is a rare and early finding indicative of leptomeningeal metastasis in patients with lung adenocarcinoma, often associated with EGFR gene mutations.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71151","citationCount":"0","resultStr":"{\"title\":\"Bloomy Rind Sign in Leptomeningeal Metastasis of Primary Lung Adenocarcinoma\",\"authors\":\"Wenyuan Tao, Xinhua Chen, Xin Zhang, Lijuan Han\",\"doi\":\"10.1002/ccr3.71151\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The bloomy rind sign, which appears as hyperintensities on FLAIR along the surface of the brainstem without gadolinium contrast enhancement, is a rare and early finding indicative of leptomeningeal metastasis in patients with lung adenocarcinoma, often associated with EGFR gene mutations.</p>\",\"PeriodicalId\":10327,\"journal\":{\"name\":\"Clinical Case Reports\",\"volume\":\"13 10\",\"pages\":\"\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.71151\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.71151\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.71151","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Bloomy Rind Sign in Leptomeningeal Metastasis of Primary Lung Adenocarcinoma
The bloomy rind sign, which appears as hyperintensities on FLAIR along the surface of the brainstem without gadolinium contrast enhancement, is a rare and early finding indicative of leptomeningeal metastasis in patients with lung adenocarcinoma, often associated with EGFR gene mutations.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).