Clinical Case Reports最新文献_第9页

Adult Wilms Tumor With Inferior Vena Cava Thrombus on an Incomplete Duplex Collecting System Ureter Fissus Proximalis Managed at a Tertiary Hospital in Tanzania: A Case Report and Literature Review

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Clinical Case Reports Pub Date : 2025-01-22 DOI: 10.1002/ccr3.70136

Amini Mitamo Alexandre, Joseph Martin Lori, Gabriel F. Mtaturu, Victor Patrick Sensa, Sylvia Bedas Nsato, Mariam Athumani Mbezi, Obadia V. Nyongole, Charles A. Mkony

{"title":"Adult Wilms Tumor With Inferior Vena Cava Thrombus on an Incomplete Duplex Collecting System Ureter Fissus Proximalis Managed at a Tertiary Hospital in Tanzania: A Case Report and Literature Review","authors":"Amini Mitamo Alexandre, Joseph Martin Lori, Gabriel F. Mtaturu, Victor Patrick Sensa, Sylvia Bedas Nsato, Mariam Athumani Mbezi, Obadia V. Nyongole, Charles A. Mkony","doi":"10.1002/ccr3.70136","DOIUrl":"10.1002/ccr3.70136","url":null,"abstract":"Wilms' tumor (WT), also known as nephroblastoma, is a malignant embryonal kidney tumor composed of embryonic cells and is the most prevalent tumor among children, but isolated cases occur infrequently in the adult population. Adult WT is defined according to the criteria of Kilton, Matthews, and Cohen, which comprise age above 15 years and histological patterns characteristic of WT. We report a case of an adult WT with venous thrombus on an incomplete duplex collecting system. To the best of our knowledge, this is the first case of adult WT with such a presentation. A 28-year-old female patient presented to our department with a 4-month history of right flank pain and flank mass and was diagnosed by abdominal contrasted CT to have a right renal tumor with tumor thrombi in the renal vein and the inferior vena cava. The CT scan also revealed a bilateral duplex collecting system with a partial (ureter fissus proximalis) on the tumor side and a complete duplex system on the contralateral side. Right radical nephrectomy with complete tumor thrombectomy via venacavotomy was performed successfully. Histopathological examination of the specimen revealed a triphasic nephroblastoma with immunohistochemistry confirmation. Postoperatively, adjuvant chemotherapy was initiated. The increasing incidence of non-syndromic WT cases associated with duplex collecting systems suggests a potential shared pathogenesis, necessitating further research.","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11752138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Levels of Acetaminophen Causing AKI: A Case Report and Literature Review

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Clinical Case Reports Pub Date : 2025-01-22 DOI: 10.1002/ccr3.70138

Hamnah Tayyab, Lavanya Dhondapati, Ashraf Ullah, Mohammed Dheyaa Marsool Marsool, Singh Jagmeet, Khabab Abbasher Hussien Mohamed Ahmed

引用次数: 0

Giant Hydatid Cyst Originating From Psoas Muscle Extending to the Iliac Bone: A Case Report 起源于腰肌延伸至髂骨的巨大包虫囊肿1例报告。

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Clinical Case Reports Pub Date : 2025-01-21 DOI: 10.1002/ccr3.70124

Mohammad Hadi Niakan, Fatemeh Mirparsa, Hamid Zaferani Arani, Sedighe Hooshmandi, Elham Peyravi

{"title":"Giant Hydatid Cyst Originating From Psoas Muscle Extending to the Iliac Bone: A Case Report","authors":"Mohammad Hadi Niakan, Fatemeh Mirparsa, Hamid Zaferani Arani, Sedighe Hooshmandi, Elham Peyravi","doi":"10.1002/ccr3.70124","DOIUrl":"10.1002/ccr3.70124","url":null,"abstract":"Hydatid cysts, caused by the Echinococcus granulosus parasite, predominantly affect the liver and lungs, but can also impact other organs such as the kidneys, brain, and muscles. Infection occurs when individuals ingest eggs from contaminated food or water, leading to cyst formation primarily in the liver. While hydatid cysts are commonly found in various endemic regions, muscular involvement is rare, particularly in the psoas muscle. This report presents a case of a muscular hydatid cyst, describes its management, and emphasizes the need for awareness and prompt intervention. A 50-year-old man presented with abdominal and left lower limb pain, along with weakness over several days. He was febrile, and a physical examination revealed pain during leg movement. Routine laboratory tests were normal. Ultrasound and computed tomography scans identified a solid cystic mass in the left lower quadrant, extending to the left lumbar muscle. After 28 days of preoperative albendazole therapy, the patient underwent surgery through a Rocky Davis incision, where a large hydatid cyst containing daughter cysts in the psoas muscle was discovered. The cyst was unroofed, and its contents were evacuated, followed by irrigation with hypertonic saline. Postoperative recovery was uneventful. He also received standard medication therapy with albendazole, and during monthly visits, no complications were observed during the one-year follow-up. This case contributes to the limited literature on muscular hydatid disease and highlights the importance of awareness among healthcare providers to ensure timely diagnosis and management.","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Treatment of Large Left Ventricular Thrombosis During Extracorporeal Membrane Oxygenation (ECMO): A Case Report and Review of the Literature 体外膜氧合（ECMO）成功治疗大左心室血栓1例报告及文献复习。

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Clinical Case Reports Pub Date : 2025-01-21 DOI: 10.1002/ccr3.70123

Xue-ting Yang, Yi-jin Chen, Han Zeng, Lei Deng, Li Chang, Yi Li, Meng-long Song, Yang Zhang, Wei Peng, Dong Wang, Hua Jiang, Hong-qiong Peng

引用次数: 0

Carbon Monoxide Toxicity Secondary to Cutaneous Methylene Chloride Exposure: A Case Report 皮肤接触二氯甲烷继发的一氧化碳毒性：一例报告。

IF 0.6

Clinical Case Reports Pub Date : 2025-01-20 DOI: 10.1002/ccr3.70141

Carine Dornbush, William Mohr, Colette Galet, Lucy Wibbenmeyer, Alexander Kurjatko

引用次数: 0

Management of Radix Entomolaris of Mandibular First Molar With Complex Root Canal Curvatures: A Case Report and Mini Review 复杂根管弯曲的下颌骨第一磨牙虫根的治疗：1例报告及综述。

IF 0.6

Clinical Case Reports Pub Date : 2025-01-20 DOI: 10.1002/ccr3.70104

Ali Chamani, Maryam Gharechahi, Reza Shakiba, Farshad Alipour

引用次数: 0

46, XY Complete Gonadal Dysgenesis (Swyer Syndrome) Presenting as Primary Amenorrhea in a Normomorphic Adult Female From Kakamega, Kenya 46、完全性性腺发育不良（Swyer综合征）在肯尼亚Kakamega一正常成年女性中表现为原发性闭经。

IF 0.6

Clinical Case Reports Pub Date : 2025-01-20 DOI: 10.1002/ccr3.70140

Christian Omoaghe

{"title":"46, XY Complete Gonadal Dysgenesis (Swyer Syndrome) Presenting as Primary Amenorrhea in a Normomorphic Adult Female From Kakamega, Kenya","authors":"Christian Omoaghe","doi":"10.1002/ccr3.70140","DOIUrl":"10.1002/ccr3.70140","url":null,"abstract":"Differences/disorders of sex development (DSDs) are a diverse group of congenital conditions that result in disagreement between an individual's sex chromosomes, gonads, and/or anatomical sex. The 46, XY DSD group is vast and includes various conditions caused by genetic variants, hormonal imbalances, or abnormal sensitivity to testicular hormones, leading to varying degrees of under-virilization. A 19-year-old phenotypically normal female from Kakamega, Kenya, presented with primary amenorrhea. Physical examination revealed Tanner stage 3 breast development, Tanner stage 4 pubic hair, normal external genitalia, and a gynoid body shape. Hormonal profile tests indicated hypergonadotropic hypogonadism with normal 17-hydroxyprogesterone and testosterone levels. MRI revealed a hypoplastic uterus and absent ovaries. Karyotyping confirmed a 46, XY genotype, leading to the diagnosis of 46, XY complete gonadal dysgenesis (Swyer syndrome). Swyer syndrome is a rare disorder of sex development, characterized by unambiguous female genitalia, bilateral streak gonads, and elevated gonadotropin levels in individuals with a 46, XY karyotype. The condition results from abnormal gonadal development due to mutations in testis-determining factors, most commonly the SRY gene. Patients typically present with primary amenorrhea and seldom have secondary sexual characteristics as this patient had. Management includes hormone replacement therapy and gonadectomy because of the increased risk of gonadal tumors. The patient was educated about her condition, initiated on combined contraceptive pills, and counseled on exploratory laparoscopic gonadectomy. This case highlights the importance of a comprehensive diagnostic approach in patients with primary amenorrhea, keeping in mind that patients with disorders of sex development may have developed secondary sexual characteristics.","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11746928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis 罕见疾病的不寻常表现：真菌性坏死性中耳炎及乳突炎1例报告。

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Clinical Case Reports Pub Date : 2025-01-20 DOI: 10.1002/ccr3.70101

Ermia Mousavi Mohammadi, Mohsen Rajati, Hossein Zarrinfar

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Risk of Biopsy and Surgical Treatment of Subglottic Paragangliomas: A Case Report 声门下副神经节瘤活检和手术治疗的风险：1例报告。

IF 0.6

Clinical Case Reports Pub Date : 2025-01-19 DOI: 10.1002/ccr3.70130

Xi-Ming Zhao, Liang Tang, Jun Liu, Yong-Hai Luo, Shi-Ling Xiong, Jiao Cui

引用次数: 0

A Rare Presentation of Fahr's Syndrome Associated With Secondary Hyperparathyroidism 罕见的Fahr综合征合并继发性甲状旁腺功能亢进。