Rahul Kumar Chaudhary, Sajjad Ahmed Khan, Prajwal Raj Bista, Lalit Kumar Rajbanshi
{"title":"Redefining Airway Management in Maxillofacial Trauma: The Strategic Implementation of Sub-Mental Intubation","authors":"Rahul Kumar Chaudhary, Sajjad Ahmed Khan, Prajwal Raj Bista, Lalit Kumar Rajbanshi","doi":"10.1002/ccr3.9589","DOIUrl":"https://doi.org/10.1002/ccr3.9589","url":null,"abstract":"<p>Submental intubation offers a valuable alternative for managing airway in patients with complex maxillofacial injuries, providing unobstructed access for surgical intervention and reducing complications associated with traditional intubation methods. It enhances both surgical visibility and patient safety.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9589","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142641796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mirtazapine: An Antidepressant for Treating Chronic, Refractory Nausea and Vomiting in a Patient With Metastatic Sarcoma Receiving Palliative Care: A Case Report","authors":"Seyedeh Golnaz Ziaei, Mamak Tahmasebi","doi":"10.1002/ccr3.9570","DOIUrl":"https://doi.org/10.1002/ccr3.9570","url":null,"abstract":"<p>Managing chronic, refractory nausea and vomiting in advanced cancer patients is challenging, especially when unrelated to cancer treatment. Mirtazapine, a tetracyclic antidepressant, effectively alleviates these symptoms, improving quality of life. It offers a promising palliative care alternative, addressing multiple symptoms and reducing polypharmacy, thereby enhancing patient satisfaction.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9570","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peritoneal Leak Causing Right Sided Hydrothorax in A Case of Chronic Kidney Disease Undergoing Continuous Ambulatory Peritoneal Dialysis: A Case Report From Nepal","authors":"Kritika Bhattarai, Ashish Acharya, Saurav Sarkar","doi":"10.1002/ccr3.9577","DOIUrl":"https://doi.org/10.1002/ccr3.9577","url":null,"abstract":"<p>Continuous ambulatory peritoneal dialysis (CAPD) is used for the maintenance dialysis in patients with end stage renal disease. Treatment's complications in CAPD generally exist, of which transudate hydrothorax falls under the minority of the cases. Here, we aim to present a case of a 51 years old female, a newly diagnosed case of chronic kidney disease (CKD) undergoing CAPD for 3 weeks who presented at our institution with complaints of difficulty in breathing. The symptom had gradually progressed after her recent CAPD session. Several investigations were sought out, of which a chest X-ray illustrated a right sided hydrothorax. Pleural fluid analysis showed a transudate characteristic, and other diagnostic tests suggested that a peritoneal fluid leak might have caused the hydrothorax. CAPD induced hydrothorax is one of the uncommon noninfectious complications associated with peritoneal dialysis; its diagnosis can be made by studying both biochemical and radiological parameters of the patient. The definitive diagnosis is made by establishing a pleuro-peritoneal communication using peritoneal scintigraphy. An immediate halt in CAPD will allow the remission of hydrothorax as mentioned below in our case report. The definitive management includes video assisted thorascopic surgery with mechanical pleurodesis. An appropriate diagnostic and management approach should be sought in CAPD induced transudate hydrothorax. An immediate halt in CAPD with surgical interventions can be considered as a treatment options for such complication.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9577","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142641794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Longhi Engelbrecht, Nina Marie Videbech, Maja Veitland Ilkjær, Asbjørn Mohr Drewes, Esben Bolvig Mark
{"title":"Pan-Alimentary Magnetic Resonance Imaging of Severe Gastroparesis May Facilitate Diagnosis and Treatment","authors":"Martin Longhi Engelbrecht, Nina Marie Videbech, Maja Veitland Ilkjær, Asbjørn Mohr Drewes, Esben Bolvig Mark","doi":"10.1002/ccr3.9578","DOIUrl":"https://doi.org/10.1002/ccr3.9578","url":null,"abstract":"<p>\u0000 \u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.9578","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142641795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fengmei Wang, Xinru Li, Ran Liu, Yao Wang, Lili Liu, Xiaoliang Zhang, Bicheng Liu
{"title":"Coexisting nutcracker phenomenon and refractory hypertension in a patient with IgA nephropathy: A case report and literature review","authors":"Fengmei Wang, Xinru Li, Ran Liu, Yao Wang, Lili Liu, Xiaoliang Zhang, Bicheng Liu","doi":"10.1002/ccr3.9542","DOIUrl":"10.1002/ccr3.9542","url":null,"abstract":"<p>The entrapment of the left renal vein (LRV) may contribute to changes in hemodynamics within kidney and could also be associated with IgA nephropathy (IgAN). Although the relationship between the nutcracker phenomenon and IgAN has not yet been elucidated, it is speculated that this patient's refractory hypertension is a combined effect of nutcracker syndrome (NCS) and IgAN.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Izat MohammadKhawajah, Sima Shamshiri Khamene, Amir Ali Mahboobipour, Elahe Radmehr, Mastaneh Moghtaderi
{"title":"Investigating the Prevalence of Hypercalciuria in Children Aged 2–16 Years With Asymptomatic Microscopic Hematuria in 2020 in Tehran Children's Medical Center","authors":"Izat MohammadKhawajah, Sima Shamshiri Khamene, Amir Ali Mahboobipour, Elahe Radmehr, Mastaneh Moghtaderi","doi":"10.1002/ccr3.9575","DOIUrl":"10.1002/ccr3.9575","url":null,"abstract":"<p>The prevalence of hypercalciuria in children is 3%–10% globally and up to 35% in the United States. Hypercalciuria in children has many presentations; it causes different metabolic disorders and can negatively affect a child's growth. It also increases the risk of low bone mineral density and urinary tract infections. In addition, it is the most widespread cause of persistent microscopic hematuria. Changes in the diet and medications in cases of advanced stage can be useful to prevent further complications. This study aimed to determine the prevalence of hypercalciuria and to investigate its relationship with different factors in children aged 2–16 years with asymptomatic microscopic hematuria in 2020 in the Children's Medical Center hospital. This retrospective cross-sectional study was performed in a population of children aged 2–16 years old with asymptomatic microscopic hematuria who were referred to the Children's Medical Center clinic in 2020. Data such as age, sex, serum creatinine level, and proteinuria were extracted from the patient's medical records, and their relationship with hypercalciuria was analyzed using logistic regression analysis. According to the inclusion criteria, 166 children with asymptomatic microscopic hematuria (72 boys and 94 girls) were included in this study. The prevalence of hypercalciuria (ratio of random urine calcium to creatinine more than 0.2) in these patients was estimated at 25% with a confidence interval of 18%–32%. In order of prevalence, the most common conditions accompanying microscopic hematuria were kidney stones, urinary tract infections, and proteinuria. The age of patients with hypercalciuria was 2 years younger on average. Each year of age increase and every 5 years of age increase between the ages of 2 and 16 years reduced the chance of hypercalciuria in this category of patients by 12% and 45%, respectively. Our findings also showed that children with a positive history of kidney stones were about 2.2 times more likely to have hypercalciuria than their counterparts, which is considered a medium effect size. Our results showed that hypercalciuria in children with hematuria is significantly related to younger age and a positive history of kidney stones.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11560804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bibek Shrestha, Pradeep Shrestha, Prabin Shrestha, Sudip Bastakoti, Prahlad Gupta, Shiva Ram Ale Magar
{"title":"SIADH secondary to rhino-orbito-cerebral mucormycosis: A case report","authors":"Bibek Shrestha, Pradeep Shrestha, Prabin Shrestha, Sudip Bastakoti, Prahlad Gupta, Shiva Ram Ale Magar","doi":"10.1002/ccr3.9491","DOIUrl":"10.1002/ccr3.9491","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Clinical Message</h3>\u0000 \u0000 <p>Invasive fungal mucormycosis and its outcome as SIADH and orbital apex syndrome is uncommon. Mucormycosis in paranasal sinuses can even lead to intracranial invasion and its treatment with the use of amphotericin B can cure improve the prognosis of the disease. Early diagnosis and prompt treatment with antifungal, endoscopic surgery, and controlling of diabetes can be beneficial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 \u0000 <p>Mucormycosis is an opportunistic invasive fungal infection which is rare and fatal and can even cause intracranial invasion leading to SIADH. The infrequency with which mucormycosis with SIADH is encountered makes it a formidable diagnostic challenge. 70-year-old women uncontrolled diabetes mellitus presented with bilious vomiting and persistent headache with ptosis, proptosis, absence of extraocular movement, pupillary light reflex, and light perception of left eye. Radiographic investigation, KOH mount, and Biopsy showed mucormycosis in sinus with intracranial extension leading to SIADH. Further investigation revealed hyponatremia, decreased plasma osmolality. Then, when diabetes was controlled and hydrocortisone and amphotericin was given along with Endoscopic sinus debridement, SIADH was well controlled. This case illustrates the potential of mucormycosis in paranasal sinuses can even lead to intracranial invasion and its treatment with the use of amphotericin B can cure improve the prognosis of the disease. Prompt diagnosis through clinical history, radiological investigation, and laboratory parameters are important and its treatment is crucial for the better prognosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navigating the Mysteries of CLIPPERS Syndrome: A Case Report of Long-Term Follow-Up","authors":"Masoud Etemadifar, Seyyed-Ali Alaei, Zahra-Sadat Mirian, Mahdi Norouzi","doi":"10.1002/ccr3.9572","DOIUrl":"10.1002/ccr3.9572","url":null,"abstract":"<p>Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome is a rare central nervous system inflammatory disorder with an unknown pathophysiology. We present the case of a 51-year-old female exhibiting clinical and radiological features consistent with CLIPPERS syndrome. She manifested diplopia, vertigo, gait ataxia, and lower limb asthenia, accompanied by impaired tandem gait, right sixth nerve palsy, and coarse horizontal nystagmus during the physical examination. Magnetic resonance imaging (MRI) revealed punctate and curvilinear lesions centered in the pons. Treatment with glucocorticoids resulted in significant clinical improvement, and the patient was discharged with a maintenance dose of prednisolone. Throughout a four-year follow-up period, the patient remained symptom-free without any relapses using the low-dose corticosteroid. The CLIPPERS syndrome diagnosis remains challenging, but recent evidence supports an autoimmune pathogenesis. Although corticosteroid treatment has shown significant clinical improvement, there are no established guidelines or clinical trials on the optimal therapeutic regimen. Despite its rarity, clinicians should consider CLIPPERS syndrome in patients with compatible clinical and radiological features to prevent irreversible neurological damage.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pouyan Aminishakib, Farzaneh Mosavat, Mahsa Bayati, Ata Garajei
{"title":"Odontogenic carcinosarcoma of the mandible: A case report","authors":"Pouyan Aminishakib, Farzaneh Mosavat, Mahsa Bayati, Ata Garajei","doi":"10.1002/ccr3.9554","DOIUrl":"10.1002/ccr3.9554","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Clinical Message</h3>\u0000 \u0000 <p>Odontogenic carcinosarcoma, a rare and challenging diagnosis, was identified in a 60-year-old male through histopathology, revealing a biphasic neoplasm with malignant epithelial and mesenchymal components. Surgical resection is crucial for management, highlighting the importance of vigilant postoperative follow-up to ensure early detection of any recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 \u0000 <p>One rare mixed malignant odontogenic tumor is odontogenic carcinosarcoma, which comprises malignant epithelial and mesenchymal components. Diagnosing odontogenic carcinosarcoma is challenging due to its rarity and atypical clinical presentation. This study reports a 60-year-old male patient who presented with a painless swelling on the right side of his face and experienced facial asymmetry for 6 months, ultimately diagnosed with odontogenic carcinosarcoma. A biphasic neoplasm with malignant alterations in both epithelial and mesenchymal components was identified upon histopathological examination. MRI imaging showed an expansile multilobulated lytic lesion with cortical erosion and extraosseous extension in the posterior region of the right mandibular body and ramus. Following contrast administration, homogeneous lesion enhancement was observed, with a few small non-enhancing necrotic areas in central parts. The patient subsequently underwent a right hemi-mandibulectomy with resection of adjacent soft tissues and neck dissection due to lymph node involvement. The resulting defect was reconstructed using a pectoralis major flap. No recurrence or metastasis was reported during the 6-month follow-up, reinforcing the positive results. This case highlights the importance of recognizing odontogenic carcinosarcoma and underscores the challenges in diagnosing and managing this rare tumor. Early identification and aggressive treatment can lead to positive outcomes, as evidenced by the absence of recurrence or metastasis in this patient during the follow-up period.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion in a patient with neuropathic pain","authors":"Nobuyuki Takahashi, Yukiko Mori, Kenji Momo, Hidetomo Murakami, Hironori Tanaka","doi":"10.1002/ccr3.9526","DOIUrl":"10.1002/ccr3.9526","url":null,"abstract":"<p>Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induces hyponatremia accompanied by uric acid reduction. We report a case of a patient with small-cell lung cancer who developed SIADH with hypouricemia after duloxetine treatment and discuss the potential underlying mechanisms. SIADH and hypouricemia improved after duloxetine was switched to mirogabalin.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"12 11","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}