{"title":"Branchial Cleft Cyst With Coexisting Tuberculous Lymphadenitis in an Elderly Patient: A Diagnostic Challenge.","authors":"Aakash Khatiwada, Rahul Mahato, Bishesh Kattel, Prajita Baral, Priyanshu Karn, Rekarna Bartaula","doi":"10.1002/ccr3.73713","DOIUrl":"https://doi.org/10.1002/ccr3.73713","url":null,"abstract":"<p><p>Cystic lateral neck masses in elderly patients require careful evaluation as clinical and cytological findings may be misleading. Histopathology remains essential for definitive diagnosis, and the uncommon coexistence of congenital lesions with tuberculous lymphadenitis should be considered in endemic regions.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73713"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149172117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2026-10-09eCollection Date: 2026-10-01DOI: 10.1002/ccr3.73719
Ayham Qatza, Hadi Alabdullah, Moayad Mosleh, Omar Zakkour, Ali Youssef
{"title":"Symptomatic Calcaneal Intraosseous Lipoma Mimicking Refractory Heel Pain: A Case Report and Review of the Literature.","authors":"Ayham Qatza, Hadi Alabdullah, Moayad Mosleh, Omar Zakkour, Ali Youssef","doi":"10.1002/ccr3.73719","DOIUrl":"https://doi.org/10.1002/ccr3.73719","url":null,"abstract":"<p><p>Intraosseous lipomas (IOLs) are rare benign primary bone tumors, most commonly affecting the calcaneus. Although often asymptomatic, IOLs may present with persistent heel pain mimicking plantar fasciitis. Accurate diagnosis depends on characteristic radiological features, whereas the management strategy remains debated between conservative and surgical approaches. A 52-year-old construction worker with 4 months of activity-related left heel pain presented with calcaneal tenderness and no systemic inflammatory signs. Radiographs and computed tomography demonstrated a well-defined calcaneal lesion with central calcification, consistent with IOLs. Surgical treatment included curettage, evacuation of lipid contents, and autologous iliac-crest bone grafting. Postoperative recovery was uncomplicated with stable neurovascular status and adequate pain control. The patient resumed unrestricted ambulation at 2 months postoperatively. At 6 months follow-up, he reported complete resolution of pain and had resumed normal weight-bearing activities without limp or functional limitation. IOLs should be included in the differential diagnosis of refractory heel pain. Surgical curettage combined with autologous bone grafting produces excellent functional outcomes and immediate structural support, preventing pathological fractures in active patients.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73719"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic Effects of Electroacupuncture on Partial-Thickness Supraspinatus Tear: Clinical Case Report.","authors":"Gholamreza Hajvalie, Ismail Ebrahimi Takamjani, Javad Sarrafzadeh, Hossein Saremi, Mohammad Reza Asadi","doi":"10.1002/ccr3.73685","DOIUrl":"https://doi.org/10.1002/ccr3.73685","url":null,"abstract":"<p><p>This case report describes clinical and imaging improvement in a patient with a partial-thickness supraspinatus tear following electroacupuncture combined with home exercise. These findings are hypothesis-generating only and should not be generalized. Randomized controlled trials are required to determine efficacy, safety, and potential clinical applicability.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73685"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13650922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ileoileocolic Type Intussusception With Double Enhanced Layer Sign in a Pediatric Patient: A Case Report.","authors":"Naoya Sakamoto, Yuuki Take, Yuri Nemoto, Kentaro Ono, Yasunari Tanaka, Kouji Masumoto","doi":"10.1002/ccr3.73707","DOIUrl":"10.1002/ccr3.73707","url":null,"abstract":"<p><p>Ileoileocolic intussusception can present without classic ultrasonographic target signs. A hyperattenuated inner bowel wall creating a \"double-enhanced layer\" on contrast-enhanced computed tomography (CT) may mimic viable bowel despite transmural necrosis and represents a diagnostic pitfall requiring early surgical intervention.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73707"},"PeriodicalIF":0.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13648017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2026-10-08eCollection Date: 2026-10-01DOI: 10.1002/ccr3.73694
Hideki Arai, Baku Hosokawa, Masahiro Nagai, Satoru Matsumoto
{"title":"Effects of Cumulative 100 km Gait Training Using Lower-Limb Orthoses in a Patient With Severe Hemiplegia and Limited Independent Ambulation Potential: Case Report.","authors":"Hideki Arai, Baku Hosokawa, Masahiro Nagai, Satoru Matsumoto","doi":"10.1002/ccr3.73694","DOIUrl":"10.1002/ccr3.73694","url":null,"abstract":"<p><p>A patient with stroke, severe hemiplegia, and limited potential for independent walking was able to achieve a modified level of independent walking after a cumulative 100 km of gait training using lower-limb orthoses. Patients with limited potential for independent walking may benefit from sufficient gait training.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73694"},"PeriodicalIF":0.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13648019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2026-10-08eCollection Date: 2026-10-01DOI: 10.1002/ccr3.73670
Jacob Beiriger, Brayden Seliger, Silvia Soule, Hilary C McCrary, Richard B Cannon
{"title":"Beyond the Oropharynx: TTMV-HPV DNA Detection in a p16-Positive Hypopharyngeal Squamous Cell Carcinoma.","authors":"Jacob Beiriger, Brayden Seliger, Silvia Soule, Hilary C McCrary, Richard B Cannon","doi":"10.1002/ccr3.73670","DOIUrl":"10.1002/ccr3.73670","url":null,"abstract":"<p><p>Plasma TTMV-HPV16 DNA provided complementary molecular evidence in a p16-positive hypopharyngeal squamous cell carcinoma, while PET/CT localized the occult left pyriform sinus primary. Serial postoperative TTMV-HPV DNA assays remained undetectable through approximately 19 months of clinical and radiographic surveillance.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73670"},"PeriodicalIF":0.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13648016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2026-10-08eCollection Date: 2026-10-01DOI: 10.1002/ccr3.73642
Sarah Nisar, Hamza Mushtaq, Muhammad Haris Khan, Fatima Sajjad, Abdullah Afridi, Noor E Fatima, Kamil Ahmad Kamil
{"title":"Post-Dengue Deep Vein Thrombosis Complicated by Pulmonary Embolism: A Case Report.","authors":"Sarah Nisar, Hamza Mushtaq, Muhammad Haris Khan, Fatima Sajjad, Abdullah Afridi, Noor E Fatima, Kamil Ahmad Kamil","doi":"10.1002/ccr3.73642","DOIUrl":"10.1002/ccr3.73642","url":null,"abstract":"<p><p>Dengue fever is commonly associated with bleeding complications, particularly in patients with thrombocytopenia. However, thrombotic events, such as venous thromboembolism, are rare and under-recognized manifestations, particularly during the recovery phase, posing diagnostic and therapeutic challenges. We report the case of a 25-year-old previously healthy male who presented with high-grade fever, myalgia, and headache and was diagnosed with dengue fever based on positive NS1 antigen testing. Dengue infection was confirmed by a positive NS1 antigen test performed on Day 3 of illness, consistent with early acute dengue infection. The diagnosis was further supported by the patient's clinical presentation, including high-grade fever, myalgia, and headache in the appropriate epidemiological context of a dengue-endemic region. During the recovery phase of the illness, he developed painful swelling of the right lower limb and progressive dyspnea. Investigations revealed markedly elevated D-dimer levels, right lower limb deep vein thrombosis on Doppler ultrasound, and bilateral pulmonary emboli with right ventricular strain on CT pulmonary angiography images. Although dengue-associated thrombosis has been reported in the setting of thrombocytopenia, as described by Ghatak et al., the present case demonstrates that thrombotic complications may also occur despite preserved platelet counts, highlighting the potential contribution of endothelial dysfunction and inflammatory activation. This case highlights the paradoxical coexistence of thrombosis and bleeding risk in dengue fever. To avoid potentially fatal thromboembolic complications in patients with dengue, early diagnosis, prompt anticoagulation, and a high index of suspicion are crucial.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73642"},"PeriodicalIF":0.6,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13648022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2026-10-06eCollection Date: 2026-10-01DOI: 10.1002/ccr3.73697
Kimiyasu Yoneyama, Motohito Nakagawa, Asuka Hara
{"title":"Successful Breast-Conserving Surgery Following Dose-Modified Neoadjuvant Chemoimmunotherapy in an 86-Year-Old Patient With Locally Advanced Triple-Negative Breast Cancer: A Case Report.","authors":"Kimiyasu Yoneyama, Motohito Nakagawa, Asuka Hara","doi":"10.1002/ccr3.73697","DOIUrl":"10.1002/ccr3.73697","url":null,"abstract":"<p><p>Patients aged ≥ 80 years with breast cancer are underrepresented in clinical trials, resulting in limited evidence regarding optimal treatment strategies, particularly for triple-negative breast cancer (TNBC). We report the case of an 86-year-old woman with locally advanced PD-L1-positive TNBC who presented with a painful 10-cm breast mass with skin invasion, clinically suspected axillary lymph node involvement, and subsequent tumor bleeding. Because of her preserved functional status, intact cognitive function, absence of significant comorbidities, and strong motivation for treatment, dose-modified neoadjuvant chemoimmunotherapy with pembrolizumab, paclitaxel, and carboplatin was administered. The tumor showed a marked response, and after four cycles complete clinical remission was achieved. Breast-conserving surgery with axillary lymph node dissection was subsequently performed, and pathological examination demonstrated a complete pathological response. The patient remains disease-free 15 months after surgery. This case highlights the importance of careful patient selection and individualized treatment planning when considering curative-intent multimodality treatment in very elderly patients with locally advanced TNBC.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73697"},"PeriodicalIF":0.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149126887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Refractory Pericardial Effusion Secondary to Central Hypothyroidism due to Empty Sella Syndrome: A Rare Case Report","authors":"Bishal Mandal, Prativa Subedi, Bishal Kumar Yadav, Bipin Pandey, Bishwa Raj Adhikari, Saurav Jha, Milan Gaihre","doi":"10.1002/ccr3.73399","DOIUrl":"10.1002/ccr3.73399","url":null,"abstract":"<p>Refractory pericardial effusion with a low free T4 but inappropriately normal TSH should prompt evaluation for central hypothyroidism, including pituitary MRI to identify treatable causes such as empty sella syndrome. Glucocorticoid cover must precede levothyroxine to prevent adrenal crisis in patients with possible hypopituitarism.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical Case ReportsPub Date : 2026-10-06eCollection Date: 2026-10-01DOI: 10.1002/ccr3.73689
Sanjida Ansari, Murari Dhungana
{"title":"Seizure Like Activity During Permanent Pacemaker Implantation: A Case of Suspected Venous Air Embolism With Acute Hypoxia.","authors":"Sanjida Ansari, Murari Dhungana","doi":"10.1002/ccr3.73689","DOIUrl":"10.1002/ccr3.73689","url":null,"abstract":"<p><p>Venous air embolism is a rare complication of pacemaker implantation. A 78 year old man developed sudden generalized stiffness, seizure-like activity, and severe hypoxia (oxygen saturation 70%) during lead manipulation without hypotension or arrhythmia. Prompt recognition, high-flow oxygen, and temporary procedural interruption led to complete recovery without neurological sequelae.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"14 10","pages":"e73689"},"PeriodicalIF":0.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}