Clinical and Experimental Dermatology最新文献_第6页

Cutaneous melanoma in situ: a review. 皮肤原位黑色素瘤：综述。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-25 DOI: 10.1093/ced/llae465

Dimitrios Karponis, Jilse Joshy, Ioannis A Stratigos, Paul J Craig, Khaylen Mistry, Birgitta van Bodegraven, Zoe C Venables, Nick J Levell

{"title":"Cutaneous melanoma in situ: a review.","authors":"Dimitrios Karponis, Jilse Joshy, Ioannis A Stratigos, Paul J Craig, Khaylen Mistry, Birgitta van Bodegraven, Zoe C Venables, Nick J Levell","doi":"10.1093/ced/llae465","DOIUrl":"https://doi.org/10.1093/ced/llae465","url":null,"abstract":"Cutaneous melanoma in situ (MIS), also known as 'stage 0 melanoma', is a collection of malignant melanocytes in the epidermis and epithelial adnexa, without evidence of microinvasion to the papillary dermis. Distinct histologic subtypes include lentigo maligna (LM), superficial spreading (SS) MIS and acral lentiginous (AL) MIS. LM is the most common subtype, usually diagnosed later in life (median age at diagnosis of 66-72 years) and associated with cumulative ultraviolet radiation exposure. SS MIS is associated with intense episodes of sun exposure and is more common on the trunk and extremities. AL MIS is seen in non-hair-bearing skin. Although rare (0.6% of MIS in England), AL MIS is found in higher proportion in more pigmented skin types compared to other MIS subtypes. Most international studies between 1990-2019 report rising incidence for MIS. US data support a deceleration in the rising incidence of LM between 2016-2019. For 2013-2019 in England, the recorded incidence of LM is plateauing, while that of other MIS is rising. Definitive diagnosis of MIS is by histological examination of biopsied skin with immunohistochemistry but can be supported with dermoscopy and reflectance confocal microscopy. Surgical treatment (excision or Mohs micrographic surgery) is the gold standard. Depending on MIS subtype, other options such as cryotherapy, topical imiquimod, radiotherapy, or watchful waiting may be appropriate. The latest 5-year net survival rates in England between 2013-2015 are 98.6% for AL MIS and exceed 100% for all other MIS. This review summarises the aetiology, pathogenesis, epidemiology, diagnosis and management of MIS.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Pediatric Case of Multiple Pilomatricomas: Assessing the Risk of Genetic Disorders. 一例小儿多发性乳头状瘤：评估遗传疾病的风险。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-25 DOI: 10.1093/ced/llae461

Soma Nakaso, Nobuaki Ishii, Masataka Akimoto, Rei Ogawa

引用次数: 0

A young woman's experience of surgery for severe hidradenitis suppurativa. 一位年轻女性接受重度化脓性扁桃体炎手术的经历。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-25 DOI: 10.1093/ced/llae463

YiXuan Goh, Sally O'Shea

引用次数: 0

Eosinophilic Dermatosis of Haematological Malignancy. 血液恶性肿瘤嗜酸性粒细胞皮肤病。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-25 DOI: 10.1093/ced/llae469

Kasthuri Nallathamby, Kat Moss, Nitin Khirwadkar, Richard Azurdia

引用次数: 0

Atopic dermatitis is associated with an increased risk of cardiovascular diseases: a large-scale, propensity-score matched US-based retrospective study. 特应性皮炎与心血管疾病风险增加有关：一项基于美国的大规模倾向匹配回顾性研究。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-24 DOI: 10.1093/ced/llae164

Henner Zirpel, Sascha Ständer, Alicja Frączek, Henning Olbrich, Ralf J Ludwig, Diamant Thaçi

{"title":"Atopic dermatitis is associated with an increased risk of cardiovascular diseases: a large-scale, propensity-score matched US-based retrospective study.","authors":"Henner Zirpel, Sascha Ständer, Alicja Frączek, Henning Olbrich, Ralf J Ludwig, Diamant Thaçi","doi":"10.1093/ced/llae164","DOIUrl":"10.1093/ced/llae164","url":null,"abstract":"Background: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease characterized by intense itch, and impacting heavily on patients' and caregivers' quality of life. Its clinical presentation is accompanied by a variety of comorbidities associated with type 2 inflammation, such as asthma, hay fever and food allergies. However, current data on cardiovascular comorbidities are inconsistent.Objectives: To identify the risk of cardiovascular diseases (CVDs) in patients with AD.Methods: Data from electronic health records of 1 070 965 patients with AD and equally distributed propensity-score matched controls were retrieved from the US Collaborative Network, part of the federated TriNetX network. Hazard ratios (HRs) for the risk of onset of CVDs with a prevalence of ≥ 1% in both cohorts within 20 years after diagnosis were determined.Results: In total, 55 CVDs belonging to 8 major cardiovascular groups were identified. Of those, 53 diagnoses displayed a significantly increased risk in patients with AD. Different diagnoses of heart failure and heart disease were found most often, followed by valve insufficiencies, arrhythmia, tachycardia, atrial fibrillation and flutter, but also major adverse cardiovascular events and venous thromboembolism. The highest HRs were displayed by the individual diagnoses of venous insufficiency, atherosclerosis of native arteries of the extremities, and unspecified diastolic (congestive) heart failure.Conclusions: AD is associated with an increased risk for multiple CVDs.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1405-1412"},"PeriodicalIF":3.7,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent oral and nasopharyngeal ulcers, facial erythema, vesicles and scars in an older woman. 一名老年女性反复出现口腔和鼻咽部溃疡、面部红斑、水泡和疤痕。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-24 DOI: 10.1093/ced/llae151

Yuan Wang, Fang Wang, Yongzhuo Wu, Fuqiong Jiang

引用次数: 0

CorrespondenceAuthor reply to 'Comment on ChatGPT and medical writing in dermatology: why should we keep writing?' by Duff et al. 作者回复 Duff 等人 "关于 ChatGPT 和皮肤科医学写作的评论：我们为什么要继续写作？

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-24 DOI: 10.1093/ced/llae178

Luca Potestio, Matteo Megna, Sara Cacciapuoti, Fabrizio Martora, Alessia Villani

引用次数: 0

Epithelioid sarcoma: a rare cause of refractory chronic skin ulcers. 上皮样肉瘤：难治性慢性皮肤溃疡的罕见病因。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-24 DOI: 10.1093/ced/llae182

Long Zhang, Xianqiong Huang, Qionghui Cheng, Xia Lei, Jinjin Wu, Jinyi Chen

引用次数: 0

Qualitative investigation of disease course, characteristics and lived experience of generalized pustular psoriasis. 对泛发性脓疱型银屑病的病程、特征和生活经历进行定性调查。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-24 DOI: 10.1093/ced/llae194

Emily A Parks, Mallory L Zaino, Bettina Trettin, Steven R Feldman

{"title":"Qualitative investigation of disease course, characteristics and lived experience of generalized pustular psoriasis.","authors":"Emily A Parks, Mallory L Zaino, Bettina Trettin, Steven R Feldman","doi":"10.1093/ced/llae194","DOIUrl":"10.1093/ced/llae194","url":null,"abstract":"Background: Generalized pustular psoriasis (GPP) is a relapsing-remitting chronic disease characterized by painful pustules with systemic symptoms that has a negative impact on quality of life. The psychosocial and economic burden of this rare condition is not well characterized.Objectives: To qualitatively characterize the cumulative burden of GPP on patients' quality of life and psychosocial wellbeing.Methods: A retrospective chart review of patients with GPP was performed to collect demographic information, followed by prospective semistructured clinical interviews. Interview transcripts were analysed using thematic analysis.Results: Three major themes were revealed: (i) burden of having a chronic disease with an unpredictable course, (ii) an inability to fulfil societal roles results in a loss of identity, and (iii) a physician-patient relationship grounded in trust and transparency can be invaluable in helping patients endure chronic disease.Conclusions: GPP has a negative impact on patients' quality of life and psychosocial wellbeing. Impairments in daily function and mental health primarily affect patients during flares and influence behaviour during periods of quiescence. A strong patient-physician relationship may help mitigate the impact of GPP.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1362-1366"},"PeriodicalIF":3.7,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

YouTube as a source of information for self-skin examinations: an analysis of content and quality. YouTube 作为皮肤自我检查的信息来源：内容与质量分析。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-10-24 DOI: 10.1093/ced/llae190

Yanci A Algarin, Anika Pulumati, Alex Reznik, Robert J Pariser

引用次数: 0