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Clinical and Experimental Dermatology最新文献

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Online Sourcing of Medications: The patient buying medication from online pharmacies abroad. 网上购药：患者从国外网上药店购买药物。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-07 DOI: 10.1093/ced/llae367
Buket Beresford-Wylie, Matthew Harries, Brett King, Andrew Y Finlay, Leila Asfour
{"title":"Online Sourcing of Medications: The patient buying medication from online pharmacies abroad.","authors":"Buket Beresford-Wylie, Matthew Harries, Brett King, Andrew Y Finlay, Leila Asfour","doi":"10.1093/ced/llae367","DOIUrl":"https://doi.org/10.1093/ced/llae367","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Treatment of Chronic Spontaneous Urticaria using Tralokinumab: A Case Report. 使用特罗凯单抗成功治疗慢性自发性荨麻疹：病例报告
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-07 DOI: 10.1093/ced/llae368
Catherine Zhu, Michael Fein, Moshe Ben-Shoshan, Lisa Iannattone, Elena Netchiporouk
{"title":"Successful Treatment of Chronic Spontaneous Urticaria using Tralokinumab: A Case Report.","authors":"Catherine Zhu, Michael Fein, Moshe Ben-Shoshan, Lisa Iannattone, Elena Netchiporouk","doi":"10.1093/ced/llae368","DOIUrl":"https://doi.org/10.1093/ced/llae368","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal Antibodies for the Management of Cutaneous Lupus Erythematosus: An Update on the Current Treatment Landscape. 治疗皮肤红斑狼疮的单克隆抗体：当前治疗格局的最新进展。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-07 DOI: 10.1093/ced/llae374
Alexander J Jafari, Christina McGee, Natasha Klimas, Adelaide A Hebert
{"title":"Monoclonal Antibodies for the Management of Cutaneous Lupus Erythematosus: An Update on the Current Treatment Landscape.","authors":"Alexander J Jafari, Christina McGee, Natasha Klimas, Adelaide A Hebert","doi":"10.1093/ced/llae374","DOIUrl":"https://doi.org/10.1093/ced/llae374","url":null,"abstract":"<p><p>Cutaneous lupus erythematosus is a complex autoimmune disease often characterized by a multitude of skin findings. Cutaneous lupus erythematosus (CLE) is generally classified into three main categories: acute cutaneous lupus (ACLE), subacute cutaneous lupus (SCLE), and chronic cutaneous lupus (CCLE). The current therapeutic guidelines for CLE include counseling patients on general measures and medication regimens. Treatment options include optimized photoprotection, avoidance of environmental triggers, corticosteroids, topical and systemic immunomodulators, and antimalarials. To date, no biologic medications (i.e., monoclonal antibodies [mAbs]) are approved for CLE. The first monoclonal antibody, belimumab, a B-lymphocyte stimulator (BLyS)-specific inhibitor, for the treatment of both systemic lupus erythematosus (SLE) and active lupus nephritis, was approved in 2011 and 2020, respectively. Anifrolumab, a type I interferon (IFN) receptor antagonist, was approved in 2021 for SLE. Other mAbs with different targets, including a novel biologic that inhibits blood dendritic cell antigen 2 (BDCA2), are currently under investigation for CLE. This review will describe the general treatment landscape for CLE. Select studies related to these various mAbs, as well as their safety profiles and efficacies demonstrated in clinical trials, will be discussed. Biologic medications can potentially augment the number of treatment options for patients living with CLE.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual case of dorsal hand papules and nodules. 手背丘疹和结节的一个不寻常病例。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-06 DOI: 10.1093/ced/llae355
Lauren MacKinnon, Nilukshi Wijesuriya, Nick Tiffin, Chara Ntala, Zainab Jiyad, Ven Samarasinghe
{"title":"An unusual case of dorsal hand papules and nodules.","authors":"Lauren MacKinnon, Nilukshi Wijesuriya, Nick Tiffin, Chara Ntala, Zainab Jiyad, Ven Samarasinghe","doi":"10.1093/ced/llae355","DOIUrl":"https://doi.org/10.1093/ced/llae355","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pustular annular erythema triggered by Empaglifozin. Empaglifozin 引发的脓疱性环状红斑。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-04 DOI: 10.1093/ced/llae373
Celine Dandoy, Jonathan M L White, Dilara Sanak, Véronique Del Marmol, Farida Benhadou
{"title":"Pustular annular erythema triggered by Empaglifozin.","authors":"Celine Dandoy, Jonathan M L White, Dilara Sanak, Véronique Del Marmol, Farida Benhadou","doi":"10.1093/ced/llae373","DOIUrl":"https://doi.org/10.1093/ced/llae373","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexuality impairment in patients with atopic dermatitis. 特应性皮炎患者的性功能障碍。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-04 DOI: 10.1093/ced/llae360
Laurent Misery, Julien Seneschal, Florence Corgibet, Bruno Halioua, Francesca Sampogna, Stéphanie Merhand, Charbel Skayem, Yaron Ben Hayoun, Charles Taieb, Delphine Staumont-Sallé, Khaled Ezzedine, Marie A Richard
{"title":"Sexuality impairment in patients with atopic dermatitis.","authors":"Laurent Misery, Julien Seneschal, Florence Corgibet, Bruno Halioua, Francesca Sampogna, Stéphanie Merhand, Charbel Skayem, Yaron Ben Hayoun, Charles Taieb, Delphine Staumont-Sallé, Khaled Ezzedine, Marie A Richard","doi":"10.1093/ced/llae360","DOIUrl":"https://doi.org/10.1093/ced/llae360","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pili annulati under the electron microscope: a case report and literature review. 电子显微镜下的环状韧带：病例报告和文献综述。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-03 DOI: 10.1093/ced/llae365
Shengzhao Chen, Xiaoshuang Yang, Zhongfa Lu
{"title":"Pili annulati under the electron microscope: a case report and literature review.","authors":"Shengzhao Chen, Xiaoshuang Yang, Zhongfa Lu","doi":"10.1093/ced/llae365","DOIUrl":"https://doi.org/10.1093/ced/llae365","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eruptive telangiectasia: a closer look at trastuzumab-emtansine cutaneous complications in breast cancer patients. 溃疡性毛细血管扩张症：仔细研究乳腺癌患者的曲妥珠单抗-依单抗皮肤并发症。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-03 DOI: 10.1093/ced/llae359
Carmen Cánovas Seva, José Sáez Padilla, María López-Pardo Rico, Cecilia Buján Bonino, Carlos Aliste Santos, Noelia Moreiras Arias
{"title":"Eruptive telangiectasia: a closer look at trastuzumab-emtansine cutaneous complications in breast cancer patients.","authors":"Carmen Cánovas Seva, José Sáez Padilla, María López-Pardo Rico, Cecilia Buján Bonino, Carlos Aliste Santos, Noelia Moreiras Arias","doi":"10.1093/ced/llae359","DOIUrl":"https://doi.org/10.1093/ced/llae359","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence in Dermatopathology: a systematic review. 皮肤病理学中的人工智能：系统综述。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-03 DOI: 10.1093/ced/llae361
Roshni Mahesh Lalmalani, Clarissa Lim Xin Yu, Choon Chiat Oh
{"title":"Artificial Intelligence in Dermatopathology: a systematic review.","authors":"Roshni Mahesh Lalmalani, Clarissa Lim Xin Yu, Choon Chiat Oh","doi":"10.1093/ced/llae361","DOIUrl":"https://doi.org/10.1093/ced/llae361","url":null,"abstract":"<p><strong>Background: </strong>Medical research, driven by advancing technologies like Artificial Intelligence (AI), is transforming healthcare. Dermatology, known for its visual nature, benefits from AI, especially in dermatopathology with digitized slides. This review explores into AI's role, challenges, opportunities, and future potential in enhancing dermatopathological diagnosis and care.</p><p><strong>Materials and methodology: </strong>Adhering to PRISMA and Cochrane Handbook standards, this systematic review explored AI's function in dermatopathology. It employed an interdisciplinary method, encompassing diverse study types and comprehensive database searches. Inclusion criteria encompassed peer-reviewed articles from 2000 to 2023, with a focus on practical AI use in dermatopathology.</p><p><strong>Results: </strong>Numerous studies have investigated AI's potential in dermatopathology. We reviewed 112 papers. Notable applications include AI classifying histopathological images of nevi and melanomas, although challenges exist regarding subtype differentiation and generalizability. AI achieved high accuracy in melanoma recognition from formalin-fixed paraffin-embedded samples but faced limitations due to small datasets. Deep learning algorithms showed diagnostic accuracy for specific skin conditions, but challenges persisted, such as small sample sizes and the need for prospective validation.</p><p><strong>Conclusion: </strong>This systematic review underscores AI's potential in enhancing dermatopathology for better diagnosis and patient care. Addressing challenges like limited datasets and potential biases is essential. Future directions involve expanding datasets, conducting validation studies, promoting interdisciplinary collaboration, and creating patient-centred AI tools to enhance dermatopathology's accuracy, accessibility, and patient-focused care.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CMV complications in DIHS/DRESS: Importance of routine monitoring and early therapeutic intervention. DIHS/DRESS 中的 CMV 并发症：常规监测和早期治疗干预的重要性。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2024-09-02 DOI: 10.1093/ced/llae372
Shingo Takei, Ryota Hayashi, Natsumi Hama, Riichiro Abe
{"title":"CMV complications in DIHS/DRESS: Importance of routine monitoring and early therapeutic intervention.","authors":"Shingo Takei, Ryota Hayashi, Natsumi Hama, Riichiro Abe","doi":"10.1093/ced/llae372","DOIUrl":"https://doi.org/10.1093/ced/llae372","url":null,"abstract":"<p><p>The fatal outcomes in DIHS/DRESS are reported to be associated with CMV reactivation. However, CMV reactivation is also observed not only in DIHS/DRESS but also in other diseases when high doses of corticosteroids are administered. Currently, it is difficult to distinguish whether CMV reactivation in DIHS/DRESS is caused by steroid-induced immunosuppression or the pathology of DIHS/DRESS. In this study, we describe the characteristic of CMV reactivation in patients with DIHS/DRESS (n=22) by comparing the frequency of reactivation and its complication with those with pemphigus vulgaris (PV) (n=21) treated with high dose of corticosteroids. The frequency of CMV reactivation showed no difference between DIHS/DRESS and PV. On the other hand, the frequency of CMV complication was higher in DIHS than PV. Our data shows the importance of monitoring the CMV complication while CMV reactivation is not unique consequence of DIHS/DRESS compared to diseases treated with high dose of corticosteroids.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142104882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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