Clinical and Experimental Dermatology最新文献

The additional photographed lesion in a teledermatology clinic for urgent suspected skin cancer. 在远程皮肤科门诊中为紧急疑似皮肤癌患者拍摄的额外病变照片。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae303

Anusha Louly Nathan, Khawar Hussain, Neil P Patel

引用次数: 0

A constellation of cutaneous reactions to chimeric antigen receptor T-cell therapy. CAR-T 细胞疗法引起的一系列皮肤反应。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae311

Fatimah Khoda, Sina Ghadiri, Timothy Palmer, Katharine Warburton

引用次数: 0

Cutaneous ulcers following high-dose prednisone. 大剂量泼尼松治疗后的皮肤溃疡。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae351

William Liakos, Leena Abdelmoity, January Fields-Meehan, Viseslav Tonkovic-Capin, Elizabeth Fite

引用次数: 0

Upadacitinib for the management of severe alopecia areata in adolescent patients: a single-centre retrospective study. 乌达帕替尼治疗青少年重度斑秃：一项单中心回顾性研究。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae309

Vincenzo Picone, Paola Nappa, Maddalena Napolitano, Maria Vastarella, Cataldo Patruno, Mariateresa Cantelli

引用次数: 0

Chatting ethically: practical recommendations for ethical use of large language models in dermatology practice, research and education. 道德聊天：在皮肤病学实践、研究和教育中合乎道德地使用大型语言模型的实用建议。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae335

Emily R Gordon, Megan H Trager, Alyssa Breneman, Lydia Dugdale, Faramarz H Samie

引用次数: 0

A peculiar post-vaccination eruption. 接种疫苗后出现奇特皮疹。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae315

Martina Volonté, Emanuele M Favale, Nicolò Di Giuli, Valeria Brazzelli, Stefania Barruscotti, Giacomo Fiandrino, Carlo F Tomasini, Camilla Vassallo

引用次数: 0

An algorithmic approach towards diagnosis of patients with hereditary reticulate pigmentary disorders: a narrative review. 诊断遗传性网状色素沉着症患者的算法方法--综述。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae322

Liza Mohapatra, Kabir Sardana, Maitreyee Panda, Rahul Mahajan

{"title":"An algorithmic approach towards diagnosis of patients with hereditary reticulate pigmentary disorders: a narrative review.","authors":"Liza Mohapatra, Kabir Sardana, Maitreyee Panda, Rahul Mahajan","doi":"10.1093/ced/llae322","DOIUrl":"10.1093/ced/llae322","url":null,"abstract":"Hereditary reticulate pigmentary disorders include a group of genetic disorders, with netlike pigmentation as their predominant presentation. Many of these hereditary reticulate pigmentary disorders have a wide array of cutaneous presentations with overlapping features. Furthermore, some of these disorders also have systemic manifestations. The overlapping features often add confusion and cause delay in diagnosis. Based on a literature search, we propose an easy-to-follow and concise diagnostic algorithm for diagnosis. This algorithm would aid in ordering a definitive genetic test. A thorough data search was done using the PubMed database with the following keywords: ('inherit*' OR 'genetic') AND ('reticulate AND pigment*'). Thereafter, a search for individual diseases was done using the keywords 'Dowling-Degos disease', 'dyschromatosis hereditaria symmetrica', 'acropigmentation of Kitamura', 'dyschromatosis universalis hereditaria', 'Naegeli-Franceschetti-Jadassohn syndrome', 'X-linked reticulate pigmentary disorder' and 'dyskeratosis congenita'. The search included case reports, case series, observational studies, narrative and systematic reviews, and clinical trials. Acquired pigmentary disorders were excluded. In total, 1994 articles were retrieved. Finally, 625 articles were included for the review. The articles were narrative reviews (40), case series (23), observational studies (44) and case reports (518). An easy-to-follow clinical diagnostic algorithm was prepared based on age of onset, distribution and other parameters. This algorithm will aid in reaching a provisional diagnosis. Furthermore, this approach will help in the genetic investigations of a case of hereditary reticulate pigmentary disorder.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"12-20"},"PeriodicalIF":3.7,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterizing the use of full- and split-thickness skin grafts among dermatologists: an international survey. 皮肤科医生使用全厚和分层植皮的特点：一项国际调查。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae295

Puo Nen Lim, Brogan Kelly Salence, William Thomas Nicholas Hunt

{"title":"Characterizing the use of full- and split-thickness skin grafts among dermatologists: an international survey.","authors":"Puo Nen Lim, Brogan Kelly Salence, William Thomas Nicholas Hunt","doi":"10.1093/ced/llae295","DOIUrl":"10.1093/ced/llae295","url":null,"abstract":"Background: The use of full-thickness and split-thickness skin grafts (FTSG/STSG) among dermatologists has not been well characterized.Objectives: To characterize the utilization of graft techniques, fixation methods and training needs pertaining to graft use among an international cohort of dermatologists.Methods: An online questionnaire was developed iteratively, and subsequently distributed between July and August 2022 to dermatologists from the UK, European countries and New Zealand (NZ).Results: In total, 150 responses were obtained from the UK, Ireland, NZ, Australia, Brazil, USA and eight European countries. Among the respondents, 23.3% (35 of 150) undertook both FTSG and STSG; 46.7% (70 of 150) performed only FTSG; and 30.0% (45 of 150) did not undertake skin grafts in their practice. Of the 67 Mohs surgeons, only 42% (28 of 67) undertook both FTSG and STSG. Overall, common donor sites for FTSG included the preauricular area (86 of 105; 81.9%) and clavicle (75 of 105; 71.4%), while the thigh was the most common donor site for STSG (30 of 35; 86%). Grafts were fixed mostly with sponge tie-over dressings and basting/quilting sutures. For STSG, most were harvested using an electric dermatome (18 of 35; 51%), freehand skin-graft knife (17 of 35; 49%) and flexible razor blade (5 of 35; 14%). Of the total, 48.0% (72 of 150) considered skin grafting an essential skill in dermatology training, and most respondents cited a lack of training opportunity and insufficient surgical cases as significant barriers.Conclusions: Our survey reveals diverse practices among an international cohort of dermatologists in the use of FTSG/STSG and highlights the need for further training.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"82-87"},"PeriodicalIF":3.7,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed diagnosis of tuberous sclerosis complex: unveiling low-level TSC2 mosaicism using targeted next-generation sequencing. 结节性硬化症复合体的延迟诊断：利用定向下一代测序揭示低水平 TSC2 嵌合。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae253

Yi-Han Chang, Kwang-Yu Chang, Chao-Hsuan Li, Pei-Lung Chen, John A McGrath, Chao-Kai Hsu

引用次数: 0

Revisiting serum storage protocols: assessing the impact of temperature variations on indirect immunofluorescence testing for pemphigus and bullous pemphigoid. 重新审视血清储存方案：评估温度变化对丘疹性荨麻疹和大疱性荨麻疹间接免疫荧光试验的影响。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-12-23 DOI: 10.1093/ced/llae289

Sumruay Pinkaew, Kanokvalai Kulthanan, Papapit Tuchinda, Leena Chularojanamontri, Bawonpak Pongkittilar, Panyapat Buranaporn, Sasipha Nuttawong, Chuda Rujitharanawong

{"title":"Revisiting serum storage protocols: assessing the impact of temperature variations on indirect immunofluorescence testing for pemphigus and bullous pemphigoid.","authors":"Sumruay Pinkaew, Kanokvalai Kulthanan, Papapit Tuchinda, Leena Chularojanamontri, Bawonpak Pongkittilar, Panyapat Buranaporn, Sasipha Nuttawong, Chuda Rujitharanawong","doi":"10.1093/ced/llae289","DOIUrl":"10.1093/ced/llae289","url":null,"abstract":"Background: Indirect immunofluorescence (IIF) plays a crucial role in the diagnosis of pemphigus and bullous pemphigoid (BP) by detecting the presence of circulating autoantibodies in the serum of patients. The standard serum transportation method requires delivery to laboratories at 2-8 °C within a day and storage at -20 to -80 °C. However, this protocol poses logistical challenges.Objectives: To carry out a study assessing how temperature variations affect the accuracy of IIF tests.Methods: This case-control study analysed 203 serum specimens: 102 from patients with pemphigus and 101 from patients with BP. Specimens were stored at -80 °C (control), 24 °C and 40 °C for 7 days before analysis to investigate variations in IIF titres between test and control conditions.Results: In pemphigus serum, 95% of specimens at 24 °C and 76% at 40 °C showed no titre difference compared with controls. Similarly, 89% of BP serum specimens at 24 °C and 82% at 40 °C matched the control titres. While 57 specimens across both groups experienced reduced titres, the decrease was primarily marginal (a 1-step reduction in 54 cases, 2-step in 3), with no transition from positive to negative results.Conclusions: Storing serum at 24-40 °C for up to 7 days before testing only slightly influences IIF outcomes for pemphigus and BP. These findings could prompt a significant revision in the existing strict transport guidelines, ensuring efficient use of resources without sacrificing the accuracy of diagnostic tests.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"77-81"},"PeriodicalIF":3.7,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0