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Clinical and Experimental Dermatology最新文献

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Safety and efficacy of biologics in patients with Down syndrome and hidradenitis suppurativa: a retrospective cohort study. 唐氏综合征和化脓性汗腺炎患者的生物安全性和有效性：一项回顾性队列研究。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf090
Linnea L Westerkam, Karla Santiago-Soltero, Alexandra Charrow, John W Frew, Christopher J Sayed
{"title":"Safety and efficacy of biologics in patients with Down syndrome and hidradenitis suppurativa: a retrospective cohort study.","authors":"Linnea L Westerkam, Karla Santiago-Soltero, Alexandra Charrow, John W Frew, Christopher J Sayed","doi":"10.1093/ced/llaf090","DOIUrl":"10.1093/ced/llaf090","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1431-1433"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin B6 catabolism and psoriasis risk: a cross-sectional study. 维生素B6分解代谢与牛皮癣风险：一项横断面研究。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf065
Ruimin Bai, Xiaoqing Cheng, Yajie Yang, Jian Zhang, Qiong Tian
{"title":"Vitamin B6 catabolism and psoriasis risk: a cross-sectional study.","authors":"Ruimin Bai, Xiaoqing Cheng, Yajie Yang, Jian Zhang, Qiong Tian","doi":"10.1093/ced/llaf065","DOIUrl":"10.1093/ced/llaf065","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis is a common autoimmune inflammatory disease. Vitamin B6 is crucial for the body's inflammatory response, yet the relationship between 4-pyridoxic acid (4-PA), pyridoxal 5'-phosphate (PLP) and vitamin B6 turnover (4-PA/PLP) in psoriasis remains unexplored.</p><p><strong>Objectives: </strong>To investigate the relationship of 4-PA, PLP and vitamin B6 catabolism with the risk of psoriasis.</p><p><strong>Methods: </strong>This cross-sectional study analysed records for 7540 participants from the US National Health and Nutrition Examination Survey. Vitamin B6 catabolism was assessed via the serum 4-PA to PLP ratio (4-PA/PLP). The primary outcome was psoriasis, evaluated using weighted univariate and multivariate logistic regression to determine odds ratios (OR) and 95% confidence intervals (CI). Subgroup analyses were performed by age, gender, body mass index (BMI), hypertension, dyslipidaemia and cardiovascular disease.</p><p><strong>Results: </strong>Of the participants, 208 had psoriasis. After adjusting for confounders, 4-PA levels in the 'cutoff above' group were positively associated with psoriasis (OR 1.51, 95% CI 1.03-2.20). Additionally, 4-PA/PLP correlated with an increased psoriasis risk (OR 1.82, 95% CI 1.02-3.26). However, PLP levels did not show a significant association. The positive link between 4-PA/PLP and psoriasis was consistent in individuals with BMI ≥ 25 kg m-² and hypertension, and in those without dyslipidaemia.</p><p><strong>Conclusions: </strong>The results revealed a significant association between 4-PA and 4-PA/PLP levels in the presence of psoriasis. However, further extensive prospective studies are necessary to establish causality.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1366-1372"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malignant melanoma arising in a sebaceous naevus leading to the discovery of a pathogenic germline MUTYH mutation: a case report. 皮脂腺痣中产生的恶性黑色素瘤导致致病种系MUTYH突变的发现：一例报告。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf052
Aymeric Hennemann, Zohair Selmani, Alexis Perales, Charlée Nardin, François Aubin
{"title":"Malignant melanoma arising in a sebaceous naevus leading to the discovery of a pathogenic germline MUTYH mutation: a case report.","authors":"Aymeric Hennemann, Zohair Selmani, Alexis Perales, Charlée Nardin, François Aubin","doi":"10.1093/ced/llaf052","DOIUrl":"10.1093/ced/llaf052","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1410-1413"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lichen nitidus. 地底nitidus .
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf048
Vijayasankar Palaniappan, Kaliaperumal Karthikeyan
{"title":"Lichen nitidus.","authors":"Vijayasankar Palaniappan, Kaliaperumal Karthikeyan","doi":"10.1093/ced/llaf048","DOIUrl":"10.1093/ced/llaf048","url":null,"abstract":"<p><p>Lichen nitidus (LN) is a rare inflammatory skin condition characterized by small, shiny, flat-topped papules, commonly affecting children and young adults. Its aetiology remains unclear, although immune-mediated pathways are suspected. LN is often asymptomatic, with papules primarily on the trunk, upper limbs and genitalia. Diagnosis relies on characteristic histopathology, notably a 'claw clutching a ball' pattern. Although it often resolves spontaneously, LN may present persistently, sometimes requiring topical treatment. This review highlights the clinical, histological and dermoscopic features of LN, discusses variants and associated systemic conditions, and offers guidance for dermatologists in managing this distinct dermatosis.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1305-1314"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical steroid withdrawal response to ciclosporin. 局部类固醇对环孢素的戒断反应。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf087
Niamh T McSwiney, Anthony Bewley
{"title":"Topical steroid withdrawal response to ciclosporin.","authors":"Niamh T McSwiney, Anthony Bewley","doi":"10.1093/ced/llaf087","DOIUrl":"10.1093/ced/llaf087","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1417-1419"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on 'Efficacy and safety of switching from baricitinib to ritlecitinib in severe alopecia areata'. 评论“Baricitinib转Ritlecitinib治疗重度斑秃的疗效和安全性”。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf085
Luca Valtellini, Andrea Sechi, Angelo V Marzano, Silvia M Ferrucci
{"title":"Comment on 'Efficacy and safety of switching from baricitinib to ritlecitinib in severe alopecia areata'.","authors":"Luca Valtellini, Andrea Sechi, Angelo V Marzano, Silvia M Ferrucci","doi":"10.1093/ced/llaf085","DOIUrl":"10.1093/ced/llaf085","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1416-1417"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chromoblastomycosis: a case series from Sumba, eastern Indonesia. 成色菌病：印度尼西亚东部松巴的一个病例系列。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf111
Gladys O Siregar, Maria Harianja, Hanggoro T Rinonce, Eddy Zulfikar, Claus Bøgh, Messe R Ataupah, Ruth D Laiskodat, Evivana S Sundari, Hardyanto Soebono, Marlous L Grijsen
{"title":"Chromoblastomycosis: a case series from Sumba, eastern Indonesia.","authors":"Gladys O Siregar, Maria Harianja, Hanggoro T Rinonce, Eddy Zulfikar, Claus Bøgh, Messe R Ataupah, Ruth D Laiskodat, Evivana S Sundari, Hardyanto Soebono, Marlous L Grijsen","doi":"10.1093/ced/llaf111","DOIUrl":"10.1093/ced/llaf111","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1447-1450"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When itch becomes unbearable. 当痒变得无法忍受。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf042
Ji Fung Yong, Fei Lai, Caitriona Hackett, Anne-Marie Tobin
{"title":"When itch becomes unbearable.","authors":"Ji Fung Yong, Fei Lai, Caitriona Hackett, Anne-Marie Tobin","doi":"10.1093/ced/llaf042","DOIUrl":"10.1093/ced/llaf042","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1480-1482"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermoscopic features of acral melanosis in patients with Fitzpatrick skin types IV-VI. 菲茨帕特里克皮肤IV-VI型少数民族肢端黑色素病的皮肤镜特征。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf082
Elijah Rodriguez, Elizabeth F Sher, Michelle Juarez, David Polsky, James Johnson, Jennifer A Stein, Prince Adotama
{"title":"Dermoscopic features of acral melanosis in patients with Fitzpatrick skin types IV-VI.","authors":"Elijah Rodriguez, Elizabeth F Sher, Michelle Juarez, David Polsky, James Johnson, Jennifer A Stein, Prince Adotama","doi":"10.1093/ced/llaf082","DOIUrl":"10.1093/ced/llaf082","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1414-1416"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyoderma gangrenosum with extracutaneous involvement: a systematic review. 坏疽性脓皮病伴皮外受累：系统回顾。
IF 3.7 4区 医学
Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf104
Sharon I Choe, Moira Shea, Martha Oberg, Elena Paz Munoz, Alex G Ortega-Loayza
{"title":"Pyoderma gangrenosum with extracutaneous involvement: a systematic review.","authors":"Sharon I Choe, Moira Shea, Martha Oberg, Elena Paz Munoz, Alex G Ortega-Loayza","doi":"10.1093/ced/llaf104","DOIUrl":"10.1093/ced/llaf104","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1443-1446"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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