Clinical and Experimental Dermatology最新文献

{"title":"Risk factors for hypertrophic scar development in chest procedures.","authors":"Emily R Gordon, Megan H Trager, Tessa LeWitt, Alyssa Breneman, Eric A Cohen, Despina Kontos, Faramarz H Samie","doi":"10.1093/ced/llaf248","DOIUrl":"10.1093/ced/llaf248","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2057-2059"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144697789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Global prevalence of mental health comorbidity in patients with acne: an analysis of trends from 1961 to 2023.","authors":"","doi":"10.1093/ced/llaf369","DOIUrl":"10.1093/ced/llaf369","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2107"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple sclerosis and alopecia areata: drug-induced alopecia areata or coexisting autoimmune phenomena?","authors":"Hannah Ross, Matthew J Harries, Marta Bertolini, Leila Asfour","doi":"10.1093/ced/llaf222","DOIUrl":"10.1093/ced/llaf222","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2044-2045"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of the treatment of Flegel disease.","authors":"Lanah Almatroud, Leo Wan, Aileen Park, Amor Khachemoune","doi":"10.1093/ced/llaf227","DOIUrl":"10.1093/ced/llaf227","url":null,"abstract":"<p><p>Flegel disease (FD) is a rare skin disease characterized by hyperkeratotic papules, predominantly on the lower extremities. Although typically benign, FD carries an increased risk of skin cancers such as squamous cell carcinoma and basal cell carcinoma, and it can cause considerable pruritus. The pathogenesis of FD remains poorly understood, with potential genetic and keratinization-related factors contributing to its development. Current treatment options include topical agents, systemic treatments, phototherapy and procedural interventions. However, no standardized treatment regimen exists. This systematic review aims to provide the first comprehensive, up-to-date analysis of treatment regimens for FD reported in the literature and highlights the need for further research to develop effective, standardized treatment protocols to improve patient care.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1945-1952"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple waxy, infiltrated plaques and nodules on the scalp.","authors":"Yi-Shan Teng, Yue-Chiu Su, Cheng-Che E Lan","doi":"10.1093/ced/llaf239","DOIUrl":"10.1093/ced/llaf239","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2096-2099"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Well-circumscribed eroded lesions on the palms of a middle-aged woman.","authors":"Louise L K St Aimee, Paul Craig, Hannah E Wainman","doi":"10.1093/ced/llaf260","DOIUrl":"10.1093/ced/llaf260","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2100-2103"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dark brown hair regrowth in a red-haired woman with alopecia areata.","authors":"Bevin Bhoyrul","doi":"10.1093/ced/llaf267","DOIUrl":"10.1093/ced/llaf267","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2078-2079"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of socioeconomic status and distance to a dermatological clinic on the disease burden of keratinocyte carcinoma and its precursors in Danish office-based dermatological practice.","authors":"Johan Sieborg, Merete Hædersdal, Ulrikke Lei, Henrik Sølvsten, Anne Braae Olesen, Gabrielle R Vinding, Anna Lei Lamberg, Alexander Egeberg, Emily Wenande","doi":"10.1093/ced/llaf262","DOIUrl":"10.1093/ced/llaf262","url":null,"abstract":"<p><strong>Background: </strong>Socioeconomic status (SES) and access to dermatological care are known to influence rates of keratinocyte carcinoma (KC). However, few studies have examined the impact of these factors on the disease burden of specific KC subtypes.</p><p><strong>Objectives: </strong>To determine the impact of SES and distance to a dermatologist on the burden of KC, determined by tumour incidence rate ratios (TIRRs) and tumour size, for nodular basal cell carcinoma (nBCC), superficial BCC (sBCC), squamous cell carcinoma (SCC) and the KC precursor, Bowen disease (BD).</p><p><strong>Methods: </strong>Using data from the nationwide Danish Skin Cancer Registry, our study included 100 705 patients with 190 468 histologically or clinically verified cases of KC/BD registered in state-funded office-based dermatology practices between 2013 and 2022. Negative binomial regression was used to calculate TIRRs; the impact on lateral tumour size was estimated with log-linear quantile regression.</p><p><strong>Results: </strong>High SES was associated with increased tumour incidence and smaller tumours for all KC subtypes. Rates of nBCC and sBCC were 2.7 times and 2.4 times higher, respectively, among the top 25% earners vs. the lowest income category [nBCC 2.74, 95% confidence interval (CI) 2.69-2.79; sBCC 2.38, 95% CI 2.30-2.47], with top earners having BCC tumours that were up to 9.7% smaller (95% CI 8.5-11.0%). The impact of distance to a dermatologist varied by KC subtype. For nBCC, increasing tumour incidence was noted with shorter distances to a dermatologist, while the opposite trend was seen for SCC and BD. Individuals living further away from a dermatologist had larger nBCC and sBCC tumours. No correlation between tumour size and distance to a dermatologist was found for SCC.</p><p><strong>Conclusions: </strong>High SES was associated with increased tumour incidence and smaller tumours for all KC subtypes, reflecting either higher rates of detection or higher rates of disease occurrence. Distance to a dermatologist was an independent predictor of KC burden, with shorter distances leading to increased tumour incidence but smaller nBCC tumours and decreased incidence of SCC.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2007-2015"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The need for national standards in documenting 2 Week Wait skin cancer clinics.","authors":"Matus Kalavsky, Shafiah Muna Abdul Gafoor, Elizabeth Orrin","doi":"10.1093/ced/llaf266","DOIUrl":"10.1093/ced/llaf266","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2074-2075"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anifrolumab for the treatment of cutaneous lupus erythematosus: a 10-case series.","authors":"Maria Elena Hernández-Salas, Celia Horcajada-Reales, Carlos Palomar-Prieto, Laura Fernández-de la Fuente, Sara Herrero-Ruiz, Ana Martínez-Lauwers Dolz, Alberto Romero-Maté","doi":"10.1093/ced/llaf272","DOIUrl":"10.1093/ced/llaf272","url":null,"abstract":"<p><p>Anifrolumab is a monoclonal antibody that targets the type I interferon receptor subunit 1. It was approved for the treatment of systemic lupus erythematosus by the US Food and Drug Administration in 2021 and by the European Medicines Agency in 2022. Although phase III clinical trials reported a statistically significant improvement in skin lesions, anifrolumab has not yet been approved for the treatment of cutaneous lupus erythematosus. We present a case series that includes 10 patients with cutaneous lupus erythematosus who demonstrated a rapid and sustained response to anifrolumab.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"2040-2043"},"PeriodicalIF":2.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144511571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}