Clinical and Experimental Dermatology最新文献_第5页

Dermoscopy: the dermatologist's stethoscope. 皮肤镜：皮肤科医生的听诊器。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae241

Stephen Hayes

引用次数: 0

Health inequities in medical documentation affecting people with skin of colour: nonspecific alopecia International Classification of Diseases codes. 影响有色人种的医疗文件健康不平等。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae094

Chrislene Olukoga, Supriya Chittajallu, Cameron Edwards, Maria Florentin, Navepreet Kaur, Josephine Pyles, Anita Haggstrom

引用次数: 0

Predicting psoriasis severity using machine learning: A systematic review. 利用机器学习预测牛皮癣严重程度：系统综述。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae348

Eric P McMullen, Yousif A Al Naser, Mahan Maazi, Rajan S Grewal, Dana Abdel Hafeez, Tia R Folino, Ronald B Vender

{"title":"Predicting psoriasis severity using machine learning: A systematic review.","authors":"Eric P McMullen, Yousif A Al Naser, Mahan Maazi, Rajan S Grewal, Dana Abdel Hafeez, Tia R Folino, Ronald B Vender","doi":"10.1093/ced/llae348","DOIUrl":"https://doi.org/10.1093/ced/llae348","url":null,"abstract":"In dermatology, the applications of machine learning (ML), an artificial intelligence (AI) subset that enables machines to learn from experience, have progressed past the diagnosis and classification of skin lesions. A lack of systematic reviews exists to explore the role of ML in predicting the severity of psoriasis. This systematic review aims to identify and summarize the existing literature on predicting psoriasis severity using ML algorithms and identify gaps in current clinical applications of these tools. OVID Embase, OVID MEDLINE, ACM Digital Library, Scopus, and IEEE Xplore were searched from inception to August, 2024. A total of 30 articles met our inclusion criteria and were included in this review. One article used serum biomarkers, while the remaining 29 used image-based models. The most common severity assessment score employed by these ML models was the Psoriasis Area Severity Index score, followed by Body Surface Area, with fifteen and five articles, respectively. The small size and heterogeneity of the existing literature are the primary limitations of this review. Progress in assessing skin lesion severity through ML in dermatology has advanced, but prospective clinical applications remain limited. ML and AI promise to improve psoriasis management, especially in non-image-based applications requiring further exploration. Large-scale prospective trials using diverse image datasets are necessary to evaluate and predict the clinical value of these predictive AI models.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tinea Capitis in the Elderly: Clinical experience of 36 cases in ten years. 老年人的头癣：十年间 36 个病例的临床经验。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae354

Alexandro Bonifaz, María Alejandra Chacón-Ruiz, Javier Araiza, Leonel Fierro-Arias, Luis Miguel Moreno-López, David Chandler

引用次数: 0

A comprehensive review of dermoscopy in melasma. 全面回顾皮肤镜在黄褐斑中的应用。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llad266

Nisal Punchihewa, Michelle Rodrigues

引用次数: 0

Dermoscopy in vitiligo, diagnostic clues and markers of disease activity: a review of the literature. 白癜风的皮肤镜检查、诊断线索和疾病活动性标志物：文献综述。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llad365

Yebin Yang, Samuel Morriss, Michelle Rodrigues

引用次数: 0

Cutaneous immune-related adverse events: incidence rates, risk factors and association with extracutaneous toxicity - a prospective study of 189 patients treated with checkpoint inhibitors at a Spanish tertiary care hospital. 皮肤免疫相关不良事件：发生率、风险因素及与皮肤外毒性的关联。西班牙一家三级医院对189名接受检查点抑制剂治疗的患者进行的前瞻性研究。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae060

Gloria Juan-Carpena, Natividad Martínez-Banaclocha, Juan Carlos Palazón-Cabanes, María Niveiro-de Jaime, Isabel Betlloch-Mas, Mar Blanes-Martínez

{"title":"Cutaneous immune-related adverse events: incidence rates, risk factors and association with extracutaneous toxicity - a prospective study of 189 patients treated with checkpoint inhibitors at a Spanish tertiary care hospital.","authors":"Gloria Juan-Carpena, Natividad Martínez-Banaclocha, Juan Carlos Palazón-Cabanes, María Niveiro-de Jaime, Isabel Betlloch-Mas, Mar Blanes-Martínez","doi":"10.1093/ced/llae060","DOIUrl":"10.1093/ced/llae060","url":null,"abstract":"Background: Clinicians are increasingly prescribing immune checkpoint inhibitors (ICIs) to treat cancer, but the real-world incidence, characteristics and risk factors of cutaneous immune-related adverse events (cirAEs) are unclear.Objectives: To determine the incidence, features and risk factors of cirAEs and to measure their possible association with extracutaneous toxicity.Methods: We conducted a prospective observational study in a Spanish tertiary care hospital, including people who started an ICI between March 2020 and May 2022. We used a survival analysis and a log-rank test to obtain and compare incidence rates, and a multivariate Cox model to detect risk factors for cirAEs.Results: We included 189 patients, 82 (43.4%) of whom presented cutaneous toxicity. The incidence of cirAEs was 75.0 per 100 person-years, with a 50.0% probability of the appearance of a cirAE at 10 months of follow-up. The most frequent cirAE category was inflammatory dermatoses, and the most frequent types were pruritus, eczema and maculopapular eruptions. ICI combination therapy, a family history of psoriasis and rheumatological and pulmonary immune-related adverse events increased the risk of cirAEs.Conclusions: We found a high incidence of cirAEs, and they occurred early in the follow-up period. Dermatologists should be involved in the management of cirAEs, especially in people with risk factors.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulse azathioprine and low-dose methotrexate vs. standard-dose methotrexate in treatment of patients with moderate-to-severe psoriasis: a randomized controlled trial. 治疗中重度银屑病患者的脉冲硫唑嘌呤（AZA）和小剂量甲氨蝶呤（MTX）与标准剂量MTX的随机对照试验。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae078

Mohamed Hussein Medhat El-Komy, Khadiga S Sayed, Gehad Gawish, Menatallah Mohamed Elaguizy, Yousra Azzazi

{"title":"Pulse azathioprine and low-dose methotrexate vs. standard-dose methotrexate in treatment of patients with moderate-to-severe psoriasis: a randomized controlled trial.","authors":"Mohamed Hussein Medhat El-Komy, Khadiga S Sayed, Gehad Gawish, Menatallah Mohamed Elaguizy, Yousra Azzazi","doi":"10.1093/ced/llae078","DOIUrl":"10.1093/ced/llae078","url":null,"abstract":"Background: Psoriasis is a common chronic, immune-mediated inflammatory skin disease. Despite the availability of several systemic therapeutic agents, treatment of psoriasis remains a challenge because of the associated adverse effects and/or the financial burden of these medications, given the chronicity of the disease.Objectives: We aimed to compare the efficacy and safety of combined pulse azathioprine (AZA) and low-dose methotrexate (MTX) vs. a conventional dose of MTX in patients with chronic plaque psoriasis.Methods: In this randomized controlled trial, 67 patients with moderate-to-severe plaque psoriasis were randomized into two groups, receiving either combined pulse AZA (300 mg weekly dose) and low-dose MTX (10 mg weekly) or conventional-dose MTX (0.3 mg kg-1 per week) for 16 weeks. Patients were assessed for treatment response using the Psoriasis Area and Severity Index (PASI) score and for the development of any adverse effects at weeks 12 and 16, and for a further 3 months after stopping treatment.Results: A statistically significantly higher proportion of the patients receiving combined pulse AZA and low-dose MTX achieved ≥ 90% improvement in PASI and 100% improvement (PASI 100) at week 12, and PASI 100 at week 16, compared with those receiving the conventional dose of MTX as monotherapy. No serious adverse events were reported during the entire study period in the two groups.Conclusions: Combination therapy using pulse AZA and low-dose MTX can be an efficacious treatment for moderate-to-severe plaque psoriasis, with a relatively good safety profile.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermatology clinic attendance rates: does the content of an SMS reminder make a difference? 皮肤科门诊就诊率：短信提醒的内容会产生影响吗？

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae104

Namiz Damani, Nawar Saffar, Paul D Yesudian

引用次数: 0

Navigating through the challenges of bullous pemphigoid and breast cancer in older adults. 应对牛皮癣和老年乳腺癌的挑战。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2024-08-22 DOI: 10.1093/ced/llae111

Li Jie Helena Yoo, Cristina Grechin, Nicola Kearney, Emily Orr, Stephanie L Ryan, Marina O'Kane

引用次数: 0