Clinical and Experimental Dermatology最新文献_第4页

Successful treatment of generalized inflammatory linear verrucous epidermal naevus with a somatic mutation in KRT10 with crisaborole 2% ointment. 用2%的crisaborole软膏成功治疗了KRT10体细胞突变的全身炎症性线状疣状表皮痣。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf059

Zhongtao Li, Qingfeng Liu, Fang Zhang, Sheng Wang

引用次数: 0

A novel technique for noninvasive diagnosis of herpesvirus-related skin conditions. 一种用于非侵入性诊断与疱疹病毒有关的各种皮肤病的新技术。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf061

Anna Elisa Verzì, Francesco Lacarrubba, Stefano Dimarco, Giuseppe Micali

{"title":"A novel technique for noninvasive diagnosis of herpesvirus-related skin conditions.","authors":"Anna Elisa Verzì, Francesco Lacarrubba, Stefano Dimarco, Giuseppe Micali","doi":"10.1093/ced/llaf061","DOIUrl":"10.1093/ced/llaf061","url":null,"abstract":"Line-field confocal optical coherence tomography (LC-OCT) is a new noninvasive imaging technique that provides high-resolution skin imaging similar to that obtained with histopathology. The aim of this study was to evaluate the usefulness of LC-OCT in the diagnosis of herpesvirus skin infections. Patients with a clinical or anamnestic suspicion of herpesvirus infection underwent LC-OCT evaluation followed by Tzanck test. The examinations were performed in a blinded manner by different dermatologists. In total, 72 patients (38 male, 34 female; age range 13-84 years) were evaluated. In 57 patients, LC-OCT enabled the recognition of typical herpetic intraepidermal vesicles containing giant ballooning/multinucleated cells, as confirmed by Tzanck test. The final diagnoses were herpes zoster in 31 patients, herpes simplex in 16 patients, varicella in 8 patients and Kaposi varicelliform eruption in 2 patients. In the remaining 15 patients, both LC-OCT and Tzanck test results excluded a diagnosis of herpetic infection. Although the diagnosis of herpesvirus skin infection is generally clinical, in patients with minimal and/or atypical cases, LC-OCT could be a rapid and valid alternative to semi-invasive/invasive or time-consuming procedures, such as the Tzanck test, viral culture, polymerase chain reaction or histopathology.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1403-1405"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term cardiovascular outcomes among adult survivors of Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective cohort study using TriNetX. Stevens-Johnson综合征和中毒性表皮坏死松解成年幸存者的长期心血管预后：一项使用TriNetX的回顾性队列研究

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf046

Sheng-Hsiang Ma, Cian-Hao Yeh, Tai-Li Chen, Chen-Yi Wu, Chih-Chiang Chen

{"title":"Long-term cardiovascular outcomes among adult survivors of Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective cohort study using TriNetX.","authors":"Sheng-Hsiang Ma, Cian-Hao Yeh, Tai-Li Chen, Chen-Yi Wu, Chih-Chiang Chen","doi":"10.1093/ced/llaf046","DOIUrl":"10.1093/ced/llaf046","url":null,"abstract":"Background: The long-term sequelae of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are increasingly being recognized. However, few studies have evaluated the long-term risk of cardiovascular diseases in these patients.Objectives: This study aimed to investigate the long-term cardiovascular outcomes in survivors of SJS/TEN.Methods: In total, 2738 SJS/TEN survivors and 2738 propensity-score-matched controls were enrolled from the US Collaborative Network in the TriNetX database. The primary outcome of this study was the development of a major cardiovascular event (MACE). Patients were followed up from 3 months after the index date until the first diagnosis of an outcome event, withdrawal from the database, or 5 January 2025.Results: We found that SJS/TEN survivors had a significantly elevated risk of MACE [hazard ratio (HR) 2.13], ischaemic heart disease (HR 1.57), cerebrovascular disease (HR 2.13) and mortality (HR 1.94) compared with the matched healthy controls. Additionally, the association remained significant in most stratifications, including female, different age groups, disease severity (SJS, SJS/TEN overlap syndrome and TEN) and initial hospitalization status.Conclusions: Some potential confounders may not be acquired in the database. In addition, detection bias is another potential source of bias in this study. This study revealed that SJS/TEN survivors have a significantly higher long-term risk of developing MACE. Understanding these sequelae may provide insights for the holistic care of SJS/TEN survivors.","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1355-1361"},"PeriodicalIF":3.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are people more concerned about photoageing than skin cancer when raising awareness about risks of skin exposure? 在提高人们对皮肤暴露风险的认识时，人们是否更关注光老化而不是皮肤癌？

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llae225

Brigitte Dreno, Thierry Passeron, Susana Puig, Henry W Lim, Chee Leok Goh, Hee Young Kang, Fatimata Ly, Akimichi Morita, Jorge Ocampo-Candiani, Sergio Schalka, Liu Wei, Anne Laure Demessant, Caroline Le Floc'h, Delphine Kerob, Jean Krutmann

引用次数: 0

Complete response of multicentric reticulohistiocytosis treated with tofacitinib. 托法替尼治疗多中心网状组织细胞增多症的完全缓解。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf076

Júlia Mercader-Salvans, Maria Luísa Santos E Silva Caldeira Marques, Vania Lukoviek-Araya, Rosa Rodríguez-Rodríguez, Lorena Expósito Pérez, Francisco Guimerá, María Arteaga-Henríquez

引用次数: 0

General dermatology and dermatology in primary healthcare. 普通皮肤科和初级卫生保健中的皮肤科。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf044

Pei-Chun Weng, Kuang-Hua Chen, Chien-Yio Lin

引用次数: 0

Trichophyton indotineae infection with toenail onychomycosis. 足趾毛癣菌感染伴甲癣病。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf089

Arnaud Jabet, Jean-Benoît Monfort, Christophe Hennequin, Arnaud Fekkar, Renaud Piarroux, Anne-Cécile Normand

引用次数: 0

A unique case of reactive perforating collagenosis secondary to upadacitinib treatment of severe atopic eczema. 一个独特的情况下，反应性穿孔胶原硬化继发于更新他替尼治疗严重特应性湿疹。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf122

Emily Morrison, Su Enn Low, Kok Ngan

引用次数: 0

Specialty Certificate Examination case for skin oncology. 皮肤肿瘤学。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf108

Sarah Fleming, Kieran Carthy, Aoife Granahan, Berbie Byrne, Madonna Andrawis, Claire Drumm, Siobhan Rafferty, Asad Salim

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Generalized eruptive keratoacanthoma (Grzybowski syndrome) associated with myelodysplastic syndrome-chronic myelomonocytic leukaemia. 泛发性角棘瘤（Grzybowski综合征）与骨髓增生异常综合征-慢性骨髓单核细胞白血病相关。

IF 3.7 4区医学

Clinical and Experimental Dermatology Pub Date : 2025-06-25 DOI: 10.1093/ced/llaf098

Andjela Arandjelovic, Guan Tan, Ellen Ma, Michelle S Goh

引用次数: 0