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Refractory granuloma annulare. 难治性肉芽肿环状。
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92a.24043
Mery Deeb, Hadeel Zainah
{"title":"Refractory granuloma annulare.","authors":"Mery Deeb, Hadeel Zainah","doi":"10.3949/ccjm.92a.24043","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24043","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"461"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does my patient need testing for PFAS 'forever chemicals'? 我的病人是否需要测试PFAS“永久化学物质”？
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92a.24082
Philip Zuccaro, Damaskini Valvi, Vasilis Vasiliou
{"title":"Does my patient need testing for PFAS 'forever chemicals'?","authors":"Philip Zuccaro, Damaskini Valvi, Vasilis Vasiliou","doi":"10.3949/ccjm.92a.24082","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24082","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"463-465"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newer diabetes drugs: Surprising shared benefits and unique side effects. 新的糖尿病药物：令人惊讶的共同好处和独特的副作用。
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92b.08025
Brian F Mandell
{"title":"Newer diabetes drugs: Surprising shared benefits and unique side effects.","authors":"Brian F Mandell","doi":"10.3949/ccjm.92b.08025","DOIUrl":"https://doi.org/10.3949/ccjm.92b.08025","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"457-458"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Should I consider single-pill combination antihypertensive therapy for my patient with high blood pressure? 我的高血压患者是否应该考虑单药联合抗高血压治疗？
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92a.25002
Maximilian C Volk, Ahmad Safdar, Luke J Laffin
{"title":"Should I consider single-pill combination antihypertensive therapy for my patient with high blood pressure?","authors":"Maximilian C Volk, Ahmad Safdar, Luke J Laffin","doi":"10.3949/ccjm.92a.25002","DOIUrl":"https://doi.org/10.3949/ccjm.92a.25002","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"467-470"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Managing the side effects of sodium-glucose cotransporter-2 inhibitors. 处理钠-葡萄糖共转运蛋白-2抑制剂的副作用。
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92a.24071
Nandan Kodur, Betemariam Sharew, M Cecilia Lansang, W H Wilson Tang
{"title":"Managing the side effects of sodium-glucose cotransporter-2 inhibitors.","authors":"Nandan Kodur, Betemariam Sharew, M Cecilia Lansang, W H Wilson Tang","doi":"10.3949/ccjm.92a.24071","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24071","url":null,"abstract":"<p><p>Although sodium-glucose cotransporter-2 (SGLT2) inhibitors are widely used because of their exceptional cardiovascular and renal benefits, their side effects and corresponding management strategies have not been well characterized to date. The latest evidence suggests that class effects of SGLT2 inhibitors include volume depletion, genital fungal infections, and euglycemic diabetic ketoacidosis, while medication-specific side effects include urinary tract infections with dapagliflozin and potential increased risk of amputations with canagliflozin. Management strategies include close monitoring, adjusting medication dosages, and temporarily holding SGLT2 inhibitors when appropriate.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"503-511"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The overlooked and undertreated perils of premature ovarian insufficiency. 被忽视和治疗不足的卵巢功能不全的危险。
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92gr.25056
Samantha F Butts
{"title":"The overlooked and undertreated perils of premature ovarian insufficiency.","authors":"Samantha F Butts","doi":"10.3949/ccjm.92gr.25056","DOIUrl":"https://doi.org/10.3949/ccjm.92gr.25056","url":null,"abstract":"<p><p>Premature ovarian insufficiency (POI) is loss of ovarian function before age 40. Genetic, autoimmune, and iatrogenic causes are well defined, but 90% of cases are idiopathic. POI prevalence is estimated to be between 3% and 4%, with many cases undiagnosed or untreated. Affected individuals experience prolonged estrogen deficiency unless hormone therapy is instituted to restore physiologic levels. Untreated POI is associated with multiple health risks, including premature death due to cardiovascular disease.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"475-482"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebrovascular complications in infective endocarditis: Challenges and considerations in management. 感染性心内膜炎的脑血管并发症：管理的挑战和考虑。
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92a.24087
Vikyath Satish, Maisha Maliha, Abhyuday Chauhan, Nieves Del Mar Morales-Gomez, Safwan Gaznabi, Daniel Lorenzatti, Justin Johannesen, Carlos A Gongora, Annalisa Filtz, Mario J Garcia, Leandro Slipczuk, Aldo L Schenone
{"title":"Cerebrovascular complications in infective endocarditis: Challenges and considerations in management.","authors":"Vikyath Satish, Maisha Maliha, Abhyuday Chauhan, Nieves Del Mar Morales-Gomez, Safwan Gaznabi, Daniel Lorenzatti, Justin Johannesen, Carlos A Gongora, Annalisa Filtz, Mario J Garcia, Leandro Slipczuk, Aldo L Schenone","doi":"10.3949/ccjm.92a.24087","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24087","url":null,"abstract":"<p><p>Many patients with infective endocarditis experience neurologic complications such as ischemic strokes, intracranial hemorrhages, or infectious intracranial aneurysms. Although data are scarce, in this review we examine how best to predict, prevent, and manage these serious complications and how they affect the appropriate timing of valve surgery for infective endocarditis.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"491-501"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucagon-like peptide-1 receptor agonists and pancreatitis: A reconcilable divorce. 胰高血糖素样肽-1受体激动剂和胰腺炎：可调和的离婚。
IF 4.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI: 10.3949/ccjm.92a.24113
Adi E Mehta, Laura D Lomeli, Kevin M Pantalone
{"title":"Glucagon-like peptide-1 receptor agonists and pancreatitis: A reconcilable divorce.","authors":"Adi E Mehta, Laura D Lomeli, Kevin M Pantalone","doi":"10.3949/ccjm.92a.24113","DOIUrl":"10.3949/ccjm.92a.24113","url":null,"abstract":"<p><p>Early clinical trials suggested that patients treated with glucagon-like peptide-1 (GLP-1) receptor agonists had a slightly increased risk of acute pancreatitis. Consequently, clinicians have avoided using GLP-1 receptor agonists in patients with a history of acute pancreatitis. However, recent large meta-analyses of clinical trial data do not support a class-wide risk. Denying these valuable therapeutic medications to patients with a history of pancreatitis seems unwarranted.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 8","pages":"483-489"},"PeriodicalIF":4.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunotherapy meets William Shakespeare. 免疫疗法与莎士比亚的结合。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-07-01 DOI: 10.3949/ccjm.92b.07025
Brian F Mandell
{"title":"Immunotherapy meets William Shakespeare.","authors":"Brian F Mandell","doi":"10.3949/ccjm.92b.07025","DOIUrl":"https://doi.org/10.3949/ccjm.92b.07025","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 7","pages":"390-391"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Most elderly patients with subclinical hypothyroidism do not need to be treated. 大多数老年亚临床甲状腺功能减退患者不需要治疗。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-07-01 DOI: 10.3949/ccjm.92c.07001
Scott Selinger
{"title":"Most elderly patients with subclinical hypothyroidism do not need to be treated.","authors":"Scott Selinger","doi":"10.3949/ccjm.92c.07001","DOIUrl":"https://doi.org/10.3949/ccjm.92c.07001","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 7","pages":"395"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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