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Dealing with the "T" (testosterone). 与 "T"（睾酮）打交道。
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-02-02 DOI: 10.3949/ccjm.91b.02024
Brian F Mandell
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引用次数: 0
Our Peer-Reviewers for 2023. 我们 2023 年的同行评审员
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-02-02
{"title":"Our Peer-Reviewers for 2023.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139671394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Should I start an SGLT-2 inhibitor in my patient with heart failure and chronic kidney disease? 对于患有心力衰竭和慢性肾病的患者，是否应该开始使用 SGLT-2 抑制剂？
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-02-02 DOI: 10.3949/ccjm.91c.02001
Taher Modarressi
{"title":"Should I start an SGLT-2 inhibitor in my patient with heart failure and chronic kidney disease?","authors":"Taher Modarressi","doi":"10.3949/ccjm.91c.02001","DOIUrl":"10.3949/ccjm.91c.02001","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139671395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
von Willebrand disease: A guide for the internist. 冯-威廉氏病：内科医生指南
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-02-02 DOI: 10.3949/ccjm.91a.22033
Varinder Kaur, Omar Elghawy, Saarang Deshpande, David Riley
{"title":"von Willebrand disease: A guide for the internist.","authors":"Varinder Kaur, Omar Elghawy, Saarang Deshpande, David Riley","doi":"10.3949/ccjm.91a.22033","DOIUrl":"https://doi.org/10.3949/ccjm.91a.22033","url":null,"abstract":"von Willebrand disease (VWD), the most common inherited bleeding disorder, results when patients either do not make enough von Willebrand factor (VWF) or make defective VWF. The pathophysiology of this disorder is complex but needs to be understood to interpret the diagnostic tests. Most patients have mild to moderate symptoms and can be adequately counseled and managed by a general internist, but some need to consult a hematologist. We review the pathophysiology of VWD, its subtypes, common presentations of each subtype, diagnostic testing, and management of mild as well as severe clinical manifestations of VWD.","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139665353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Reply: Should I start an SGLT-2 inhibitor in my patient with heart failure and chronic kidney disease? 回复我是否应该为心力衰竭和慢性肾病患者开始使用 SGLT-2 抑制剂？
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-02-02 DOI: 10.3949/ccjm.91c.02002
Pooja Prasad, Megha Prasad
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引用次数: 0
When should we consider SGLT-2 inhibitors in patients with acute decompensated heart failure? 急性失代偿性心力衰竭患者何时应考虑使用 SGLT-2 抑制剂？
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-02-02
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引用次数: 0
What are the management considerations for venous thromboembolic events in patients with cirrhosis? 肝硬化患者静脉血栓栓塞事件的处理注意事项有哪些？
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-02-02 DOI: 10.3949/ccjm.91a.23045
Marie M Plante, Emily B Wolf, Razvan M Chirila
{"title":"What are the management considerations for venous thromboembolic events in patients with cirrhosis?","authors":"Marie M Plante, Emily B Wolf, Razvan M Chirila","doi":"10.3949/ccjm.91a.23045","DOIUrl":"10.3949/ccjm.91a.23045","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139671397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2023 Update in ambulatory general internal medicine. 2023 年门诊普通内科最新进展。
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-01-02 DOI: 10.3949/ccjm.91a.23056
Jason T Alexander, Simran K Singh, Sachin D Shah, Brianna Lambert, Jeremy P Smith
{"title":"2023 Update in ambulatory general internal medicine.","authors":"Jason T Alexander, Simran K Singh, Sachin D Shah, Brianna Lambert, Jeremy P Smith","doi":"10.3949/ccjm.91a.23056","DOIUrl":"10.3949/ccjm.91a.23056","url":null,"abstract":"<p><p>The practice of outpatient medicine is demanding, encompasses a wide scope of practice, and leaves little time for internists to stay up to date with the current literature. This article reviews 5 studies published in 2022 and 2023 that have the potential to change the practice of outpatient medicine. Topics covered include chronic kidney disease, secondary cardiovascular disease, kidney stones, obesity, and lipid management.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastric intestinal metaplasia and gastric cancer prevention: Watchful waiting. 胃肠化生与胃癌预防：谨慎等待
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-01-02 DOI: 10.3949/ccjm.91a.23015
Shrouq Khazaaleh, Mohammad Alomari, Mamoon Ur Rashid, Daniel Castaneda, Fernando J Castro
{"title":"Gastric intestinal metaplasia and gastric cancer prevention: Watchful waiting.","authors":"Shrouq Khazaaleh, Mohammad Alomari, Mamoon Ur Rashid, Daniel Castaneda, Fernando J Castro","doi":"10.3949/ccjm.91a.23015","DOIUrl":"10.3949/ccjm.91a.23015","url":null,"abstract":"<p><p>Gastric intestinal metaplasia (GIM), a common histologic finding, is associated with increased risk of gastric cancer, and GIM associated with <i>Helicobacter pylori</i> infection is classified as an environmental metaplastic atrophic gastritis. Patients may be asymptomatic or present with various dyspeptic symptoms. Autoimmune metaplastic atrophic gastritis is a less common but important cause of chronic gastritis. The Correa cascade describes the evolution of precancerous mucosal changes that lead to development of GIM, with differentiation of 2 histologic types of GIM (complete and incomplete) and the consequences of each type. The risk of progression to malignancy is higher with incomplete GIM. It is also higher for those who immigrate from regions with a high incidence of <i>H pylori</i> infection to areas where the incidence is low. Guidelines regarding endoscopic management of GIM vary by geographic region.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nonstatin therapy to reduce low-density lipoprotein cholesterol and improve cardiovascular outcomes. 非司他汀疗法可降低低密度脂蛋白胆固醇，改善心血管预后。
IF 6.1 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2024-01-02 DOI: 10.3949/ccjm.91a.23058
Abhayjit Singh, Leslie S Cho
{"title":"Nonstatin therapy to reduce low-density lipoprotein cholesterol and improve cardiovascular outcomes.","authors":"Abhayjit Singh, Leslie S Cho","doi":"10.3949/ccjm.91a.23058","DOIUrl":"10.3949/ccjm.91a.23058","url":null,"abstract":"<p><p>Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality, with low-density lipoprotein (LDL) cholesterol being a causative risk factor. Though statins have a decades-long track record of efficacy and safety, nonstatin agents may be used to reduce LDL cholesterol as an adjunct or alternative to statin therapy. Several new nonstatin medications have been approved in recent years, with robust data from clinical trials supporting their use in atherosclerotic disease. This review addresses the indications, evidence, and important prescribing considerations for using nonstatin lipid-lowering therapy and proposes a practical approach for determining when to initiate nonstatin therapy.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":null,"pages":null},"PeriodicalIF":6.1,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139086025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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