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Amoxicillin rash in infectious mononucleosis. 传染性单核细胞增多症的阿莫西林皮疹。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24039
Yasuhiro Kano
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引用次数: 0
IgA nephropathy: Update on pathogenesis and treatment. IgA肾病：发病机制和治疗的最新进展
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24105
Seshma Ramsawak, Scott Cohen, Andrea Linares, Corey Cavanaugh
{"title":"IgA nephropathy: Update on pathogenesis and treatment.","authors":"Seshma Ramsawak, Scott Cohen, Andrea Linares, Corey Cavanaugh","doi":"10.3949/ccjm.92a.24105","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24105","url":null,"abstract":"<p><p>The pathogenesis of immunoglobulin (Ig) A nephropathy is described through a \"4-hit\" model involving production of galactose-deficient IgA, production of autoantibodies to galactose-deficient IgA, and subsequent deposition of immune complexes in the kidney glomerulus. Diagnosis remains dependent on a kidney biopsy, often after hematuria or proteinuria is detected on urinalysis. The cornerstone of therapy still involves renin-angiotensin-aldosterone system inhibitors or corticosteroids; however, new therapies targeting key aspects of the pathogenesis of IgA nephropathy are being introduced.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"373-383"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
My adult patient's hypercholesterolemia is not responding to statins-what's next? 我的成年病人的高胆固醇血症对他汀类药物没有反应——下一步怎么办？
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24117
Faaiq N Aslam, Mohamed G Ibrahim, Razvan Chirila
{"title":"My adult patient's hypercholesterolemia is not responding to statins-what's next?","authors":"Faaiq N Aslam, Mohamed G Ibrahim, Razvan Chirila","doi":"10.3949/ccjm.92a.24117","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24117","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"347-351"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension? 对于新诊断为肺动脉高压的患者，我应该开始抗凝治疗吗？
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24083
Tark Abou-Elmagd, Shraddha Narechania
{"title":"Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension?","authors":"Tark Abou-Elmagd, Shraddha Narechania","doi":"10.3949/ccjm.92a.24083","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24083","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"339-343"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct oral anticoagulants: Challenging prescribing scenarios in everyday practice. 直接口服抗凝剂：在日常实践中具有挑战性的处方方案。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24061
Syed Bukhari, Mohamed Ghoweba, Syed Zamrak Khan, Ammar Saati, Marcelo Gomes
{"title":"Direct oral anticoagulants: Challenging prescribing scenarios in everyday practice.","authors":"Syed Bukhari, Mohamed Ghoweba, Syed Zamrak Khan, Ammar Saati, Marcelo Gomes","doi":"10.3949/ccjm.92a.24061","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24061","url":null,"abstract":"<p><p>Direct oral anticoagulants (DOACs) are preferred to vitamin K antagonists for treating venous thromboembolism and nonvalvular atrial fibrillation, primarily because of comparable efficacy, consistent dosing, and fewer drug-drug interactions. However, major trials that led to the approval of DOACs excluded subsets of patients who are challenging to treat in the primary care setting, including patients with extreme body weight, advanced kidney disease, and advanced cirrhosis, and those who have undergone bariatric surgery. The authors review the available evidence and outline current recommendations to help guide the appropriate use of DOACs in these patients.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"353-361"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively. 别嘌呤醇过敏是罕见的，严重的，部分可以避免的，但别嘌呤醇仍然可以有效地使用。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92b.06025
Brian F Mandell
{"title":"Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively.","authors":"Brian F Mandell","doi":"10.3949/ccjm.92b.06025","DOIUrl":"https://doi.org/10.3949/ccjm.92b.06025","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"326-328"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-output heart failure from arteriovenous dialysis access: A structured approach to diagnosis and management. 动静脉透析引起的高输出心力衰竭：一个结构化的诊断和管理方法。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24114
Maximilian C Volk, Bianca Honnekeri, Joanna Ghobrial, Mazen Hanna, Sanjeeb Bhattacharya, Lee Kirksey, J Emanuel Finet, Heba Wassif
{"title":"High-output heart failure from arteriovenous dialysis access: A structured approach to diagnosis and management.","authors":"Maximilian C Volk, Bianca Honnekeri, Joanna Ghobrial, Mazen Hanna, Sanjeeb Bhattacharya, Lee Kirksey, J Emanuel Finet, Heba Wassif","doi":"10.3949/ccjm.92a.24114","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24114","url":null,"abstract":"<p><p>High-output heart failure can be a complication of having an arteriovenous fistula (or graft) for hemodialysis access. This review details the pathophysiology, diagnosis, and management of this serious but underdiagnosed condition.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"362-371"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nitrogen: The unsung hero of vascular physiology. 氮：血管生理学的无名英雄。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24120
Adam J Brown
{"title":"Nitrogen: The unsung hero of vascular physiology.","authors":"Adam J Brown","doi":"10.3949/ccjm.92a.24120","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24120","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"344-346"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe cutaneous reaction induced by allopurinol. 别嘌呤醇引起严重皮肤反应。
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-06-02 DOI: 10.3949/ccjm.92a.24063
Pietro Bocchi, Lorenza Terroni, Corrado Pattacini
{"title":"Severe cutaneous reaction induced by allopurinol.","authors":"Pietro Bocchi, Lorenza Terroni, Corrado Pattacini","doi":"10.3949/ccjm.92a.24063","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24063","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 6","pages":"331-333"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do I need to treat supine hypertension in my hospitalized patient? 住院病人需要治疗仰卧位高血压吗？
IF 3.4 4区 医学
Cleveland Clinic Journal of Medicine Pub Date : 2025-05-01 DOI: 10.3949/ccjm.92a.24092
Katherine Sherman, Robert Lichtenberg
{"title":"Do I need to treat supine hypertension in my hospitalized patient?","authors":"Katherine Sherman, Robert Lichtenberg","doi":"10.3949/ccjm.92a.24092","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24092","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 5","pages":"285-289"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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