被忽视和治疗不足的卵巢功能不全的危险。

IF 4.1 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Cleveland Clinic Journal of Medicine Pub Date : 2025-08-01 DOI:10.3949/ccjm.92gr.25056

Samantha F Butts

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引用次数: 0

摘要

卵巢功能不全（POI）是指40岁以前卵巢功能的丧失。遗传、自身免疫和医源性病因明确，但90%的病例是特发性的。POI患病率估计在3%至4%之间，许多病例未得到诊断或未经治疗。受影响的个体经历长期雌激素缺乏，除非制定激素治疗以恢复生理水平。未经治疗的POI与多种健康风险相关，包括心血管疾病导致的过早死亡。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The overlooked and undertreated perils of premature ovarian insufficiency.

Premature ovarian insufficiency (POI) is loss of ovarian function before age 40. Genetic, autoimmune, and iatrogenic causes are well defined, but 90% of cases are idiopathic. POI prevalence is estimated to be between 3% and 4%, with many cases undiagnosed or untreated. Affected individuals experience prolonged estrogen deficiency unless hormone therapy is instituted to restore physiologic levels. Untreated POI is associated with multiple health risks, including premature death due to cardiovascular disease.

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来源期刊

Cleveland Clinic Journal of Medicine 医学-医学：内科

CiteScore

3.80

自引率

0.00%

发文量

109

审稿时长

6-12 weeks

期刊介绍： The mission of Cleveland Clinic Journal of Medicine (CCJM) is to provide its readers with up-to-date, practical, clinical information relevant to internal medicine, cardiology, and related fields. Consistent with this mission, CCJM focuses on timely review articles and other content that has a continuing-education orientation rather than on original research or case reports. CCJM authors, drawn from Cleveland Clinic and other top medical institutions throughout the world, are asked to identify new findings that are changing the practice of medicine and to advise readers how to apply them in daily patient care. Authors are chosen for their experience, acquired through caring for patients, teaching other physicians, and researching clinical questions.