Clinical and Experimental Optometry最新文献

{"title":"Rare presentation of unilateral multifocal circumscribed choroidal haemangiomas.","authors":"Carolina Cruz-Wegener, Timothy Murray, Aaron Gold, Belinda Rodriguez, Judith Guillaume","doi":"10.1080/08164622.2025.2542316","DOIUrl":"10.1080/08164622.2025.2542316","url":null,"abstract":"","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"790-794"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pigmented paravenous retinochoroidal atrophy: a case misdiagnosed as serpiginous choroidopathy.","authors":"Deniz Berk Morkan, Kemal Tekin, Mehmet Yasin Teke","doi":"10.1080/08164622.2025.2534718","DOIUrl":"10.1080/08164622.2025.2534718","url":null,"abstract":"","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"806-808"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemotherapy-associated retinal ischaemia and silent macular oedema: a docetaxel-oxaliplatin-induced case.","authors":"Ece Ozal, Serhat Ermis, Murat Karapapak, Ozgu Canbolat Kaplan, Sadik Altan Ozal","doi":"10.1080/08164622.2025.2528359","DOIUrl":"10.1080/08164622.2025.2528359","url":null,"abstract":"","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"795-800"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144682137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early detection of ocular surface squamous neoplasia with corkscrew vascular pattern.","authors":"Arpita Wadhva, Harshita Pandey","doi":"10.1080/08164622.2025.2564695","DOIUrl":"10.1080/08164622.2025.2564695","url":null,"abstract":"","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"783-785"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contact lenses and digital eye strain.","authors":"Phillip T Yuhas","doi":"10.1080/08164622.2025.2578331","DOIUrl":"10.1080/08164622.2025.2578331","url":null,"abstract":"<p><p>Digital eye strain (DES) is a group of eye- and vision-related problems elicited by engagement with screens. Over half of screen users experience its symptoms, which include eyestrain, headaches, blurred vision, dry eyes, and neck and shoulder pain. Although contact lenses are a popular option for the correction of refractive error, their role in the aetiology and management of DES is still emerging. Recent review publications on DES only briefly discuss contact lenses. Thus, there is a need (1) to synthesise the current body of literature that has examined the relationship between contact lenses and DES and (2) to identify gaps in the literature that are barriers to employing contact lenses to manage DES. The purpose of this narrative review is to evaluate evidence of ways in which contact lenses may contribute to and may help relieve DES. Although there is little direct evidence to support or refute the use of contact lenses for the management of DES, advances in contact-lens technology to maintain the ocular surface and to correct vision at multiple distances in multiple gazes support the potential of future research. Moreover, there is little high-quality evidence that blue-light filters reduce the symptoms of DES. Nevertheless, eye care professionals should consider the aforementioned potential benefits of wearing contact lenses during computer tasks, versus possible lens-associated ocular-surface disruption and residual astigmatism, when discussing management options with patients. Future gains in knowledge of the interaction between DES and contact lenses will have significance to eye care professionals and to their patients.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"579-594"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145512342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modernising vision standards for driver licensing: a Trans-Tasman call for reform.","authors":"Sasha Patil, Graham Wilson","doi":"10.1080/08164622.2025.2571157","DOIUrl":"10.1080/08164622.2025.2571157","url":null,"abstract":"","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"774-777"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145343959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Level of reactive oxygen species in keratoconic eyes wearing scleral lenses.","authors":"Shruti Dagar, Asif Iqbal, Muthuvel Bharathselvi, Narayanasamy Angayarkanni, Divya Giridhar, Radhika Natarajan","doi":"10.1080/08164622.2025.2578336","DOIUrl":"10.1080/08164622.2025.2578336","url":null,"abstract":"<p><strong>Clinical relevance: </strong>Oxidative stress and elevated reactive oxygen species (ROS) are implicated in corneal pathologies such as keratoconus. Understanding how scleral lens (SL) wear influence these mechanisms is important for optimizing patient management.</p><p><strong>Background: </strong>To assess the alteration in ROS level of keratoconic eyes wearing SL.</p><p><strong>Methods: </strong>Ocular surface tears (T₀) were collected at baseline and 6 hours of lens wear (T₆) on Day 1 and 1 month from 26 keratoconic eyes. SL fluid reservoir (SL_FR) was collected after 6 hours of lens wear on Day 1 (SL_FR Day 1) and at 1 month (SL_FR 1 month). ROS levels were measured using fluorimetry from Schirmer's strip tear samples and the SL_FR samples. Visual acuity, Schirmer's values, and Ocular Surface Disease index questionnaire was also assessed.</p><p><strong>Results: </strong>The ROS levels of T₀ 1 month showed significant reduction after 6 hours of SL wear (<i>p</i> < 0.001). Similarly, the ROS level of SL_FR decreased after 1 month of SL wear compared to Day 1 (<i>p</i> = 0.007). ROS level in SL_FR at Day 1 and 1 month showed significant reduction when compared to T₀ 1 month value (<i>p</i> = 0.002, <i>p</i> < 0.001 respectively). A statistically significant increase in T₀ value was noted at 1 month time point when compared to day 1 values (<i>p</i> = 0.005). The baseline ROS levels were higher in collagen cross-linked eyes (<i>p</i> = 0.01), while non-collagen cross-linked eyes showed a reduction in ROS levels of SL_FR (<i>p</i> = 0.01) after 1 month of SL wear. Visual acuity and ocular surface disease index score showed significant improvement after 6 hours and 1 month compared to baseline (<i>p</i> < 0.001 and <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>ROS level reduced in the SL_FR after 1 month and in tears after 6 hours with SL in KC patients. This indicates the effectiveness of SL in reducing ROS level of SL_FR which might have association with keratoconus pathogenesis, warrants further analysis.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"603-613"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145512339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differentiating superior segment optic nerve hypoplasia from normal-tension glaucoma in Chinese patients.","authors":"Yue Ying, Mengrui Hao, Yanan Sun, Qilian Sheng, Ye Lin Kwan, Xiangmei Kong","doi":"10.1080/08164622.2025.2569622","DOIUrl":"10.1080/08164622.2025.2569622","url":null,"abstract":"<p><strong>Clinical relevance: </strong>Careful interpretation of optical coherence tomography findings facilitates recognition of superior segment optic nerve hypoplasia (SSONH). This helps distinguish SSONH from normal-tension glaucoma, prevents unnecessary treatment, and enables for appropriate patient monitoring during clinical practice.</p><p><strong>Background: </strong>Literature regarding Chinese SSONH patients remains undocumented. Previous studies focused mainly on cases with visual-field defects. This study aims to explore methods for differentiating SSONH and early-stage normal-tension glaucoma.</p><p><strong>Methods: </strong>This retrospective study included SSONH (<i>n</i> = 22), normal-tension glaucoma (<i>n</i> = 22) and control (<i>n</i> = 20) eyes. Retinal nerve fibre layer and ganglion cell complex thickness were combined for differential diagnosis. Optimal cut-off values were chosen based on clinical requirement weighing sensitivity and specificity.</p><p><strong>Results: </strong>Retinal nerve fibre layer thinning was observed in SSONH eyes except temporal-inferior quadrant, and in normal-tension glaucoma eyes except temporal-upper sector. Ganglion cell complex thinning was pronounced in normal-tension glaucoma eyes and superior hemi of SSONH eyes. Compared to the normal-tension glaucoma group, retinal nerve fibre layer of SSONH eyes was thinner in nasal-superior hemi and thicker in temporal-inferior quadrant. When the ratio of inferior-temporal octant thickness to superior-nasal octant thickness ≥1.788 or the ratio of temporal-inferior to nasal-superior quadrant retinal nerve fibre layer thickness ≥1.387, the sensitivity and specificity for identifying SSONH are 77.27% and 100.00%. When inferior-hemi ganglion cell complex thickness ≥85 μm the same retinal nerve fibre layer ratio ≥1.101, the sensitivity and specificity reached 91.11% and 88.43%. To differentiate SSONH from controls, the best-performing parameter was sum of nasal superior 3/4 retinal nerve fibre layer at 529 μm.</p><p><strong>Conclusion: </strong>The specific retinal nerve fibre layer and ganglion cell complex thinning patterns of SSONH and normal-tension glaucoma patients may help with differentiation. Combining retinal nerve fibre layer and ganglion cell complex thickness may provide additional value in recognising SSONH.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"670-678"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145354071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing the operating conditions of 'Ocula AI' in capturing the pupillary light reflex.","authors":"Sieu K Khuu, Rebecca He, Brendan O'Brien","doi":"10.1080/08164622.2025.2598018","DOIUrl":"10.1080/08164622.2025.2598018","url":null,"abstract":"<p><strong>Clinical relevance: </strong>Pupillary light reflex testing via mobile apps offers a low-cost, and accessible method for assessing eye and neurological function. Its use may enable rapid screening and monitoring of eye disease, brain injury and neurological disorders, supporting early detection, telemedicine applications, and clinical decision-making in and outside clinical environments.</p><p><strong>Background: </strong>Rapid advances in technology have made it possible to assess human brain health with personal handheld devices through quantification of visual reflexes such as the pupillary light reflex (PLR). The study examined the effectiveness of a cutting-edge smartphone application, Ocula AI (Equinox), to capture and quantify the PLR compared to an established clinical-standard device, the PLR-3000 pupillometer (NeurOptics).</p><p><strong>Methods: </strong>Both Ocula AI and the PLR-3000 device captures the PLR waveform providing estimates of key metrics such as latency, maximum and minimum pupils, and constriction and dilation velocities. The ability of Ocula AI to capture the PLR was assessed under different indoor illumination conditions (indicated by illuminance levels ranging from 0 to 1000 lux) in 16 healthy young adults and key metrics were compared to the outputs of the PLR-3000 device.</p><p><strong>Results: </strong>Ocula AI was capable of capturing the PLR up to approximately 1000 lux, at which point the pupils are maximally constricted. Comparison and Bland-Altman plot analyses showed that Ocula AI captured the PLR and estimated key metrics of the PLR waveform to a similar standard (and were not significantly different) to the PLR-3000 device.</p><p><strong>Conclusions: </strong>The present study provided preliminary evidence demonstrating that nascent technologies now available on mobile devices are capable of providing accurate and easy estimation of the PLR. The development of such technologies offers a cost-effective solution and expands the scope of PLR testing (as a measure of neural function) to a range of environments and situations not limited to laboratory or clinical settings.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"679-688"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145721268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biometry in patients with asymmetric primary angle closure disease.","authors":"Amit Bidasaria, Amrita Dey, Mihir A Lagvankar, Wadke Vidya Arunkumar","doi":"10.1080/08164622.2025.2589390","DOIUrl":"10.1080/08164622.2025.2589390","url":null,"abstract":"<p><strong>Clinical relevance: </strong>Early diagnosis, close monitoring, and timely intervention in patients with unilateral primary angle closure disease is necessary to prevent visual loss due to glaucoma.</p><p><strong>Background: </strong>The aim of this study is to investigate the biometric parameters of eyes in patients with asymmetric primary angle closure disease and to determine the biometric differences that can predispose to Primary Angle Closure Glaucoma (PACG).</p><p><strong>Methods: </strong>This cross-sectional study included 224 eyes of 112 patients. Eyes with PACG were grouped as group A1 and fellow eyes of the same patient with either primary angle closure suspect or primary angle closure were grouped as group A2. Controls included healthy age and sex-matched patients with no evidence of glaucoma. These patients underwent clinical and ocular biometric measurements, including axial length, anterior chamber depth, lens thickness, and keratometry. Lens axial factor and relative lens position were calculated from the above ocular parameters. The differences in ocular biometric parameters between the cases and controls were compared and analysed.</p><p><strong>Results: </strong>There was a significant difference in the mean anterior chamber depth between the cases. Relative lens position was found to be anterior in group A1 (0.220 ± 0.012) as compared to group A2 (0.223 ± 0.013), which was statistically significant (<i>p</i> = 0.002). There was no statistically significant difference in the mean axial length, mean lens thickness or mean lens axial factor in cases or controls.</p><p><strong>Conclusion: </strong>In a patient with primary angle closure disease, a relative anterior placement of the crystalline lens may predispose the eye to earlier occurrence of glaucomatous damage.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"652-659"},"PeriodicalIF":1.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145630579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}