{"title":"A bibliometric evaluation of scientific productivity in meibomian gland dysfunction research.","authors":"Bedia Kesimal, Sücattin İlker Kocamış","doi":"10.1080/08164622.2025.2507397","DOIUrl":"https://doi.org/10.1080/08164622.2025.2507397","url":null,"abstract":"<p><strong>Clinical relevance: </strong>Meibomian gland dysfunction (MGD) is a major contributor to dry eye disease, affecting a large proportion of the population and leading to significant discomfort and ocular surface complications. Understanding trends in MGD research, including advancements in diagnostic technologies, therapeutic approaches, and interdisciplinary collaborations, is critical for improving clinical practices.</p><p><strong>Background: </strong>This study aims to perform a bibliometric analysis on MGD to assess the current international status of meibomian gland dysfunction research and identify the most influential contributors (journals, countries, authors) and research topics in this field.</p><p><strong>Methods: </strong>Data from studies on MGD were obtained using the Web of Science Core Collection on Science Citation Index Expanded database. Information regarding journals, titles, text, keywords, references, citations, author names, author institutions, and countries was recorded for each publication. The data were analysed using features of the Web of Science Core Collection website and the VOSviewer visualisation tool.</p><p><strong>Results: </strong>A total of 1313 articles published between 1980 and 2024 were identified. The number of articles published in the last 10 years was found to be 3.01 times greater than in all previous years combined. The United States and China were the most productive countries, with the highest number of articles and citations. The most productive institutions were located in the United States and Japan. The most prolific author was Reiko Arita. The most frequently cited article was titled 'The International Workshop on Meibomian Gland Dysfunction: Report of the Subcommittee on Anatomy, Physiology, and Pathophysiology of the Meibomian Gland'. Recent and emerging keywords include 'intense pulsed light', 'meibography', 'lipiflow', 'artificial intelligence', 'meibogenesis', 'lipidomics' and 'human meibomian gland epithelium', reflecting current trends in MGD research.</p><p><strong>Conclusions: </strong>This study provides an overview of the current status and trends in MGD research, which may help clinicians and researchers better understand this field and predict its future directions.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neville Chiavaroli, Simon Backhouse, Anthea Cochrane, Isabelle Jalbert, Geraint Phillips, Katrina L Schmid
{"title":"Promoting best practice in assessment - a professional development initiative for optometry programs.","authors":"Neville Chiavaroli, Simon Backhouse, Anthea Cochrane, Isabelle Jalbert, Geraint Phillips, Katrina L Schmid","doi":"10.1080/08164622.2025.2505561","DOIUrl":"https://doi.org/10.1080/08164622.2025.2505561","url":null,"abstract":"","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-6"},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ocular injuries and outcomes secondary to Nerf guns in an optometric setting.","authors":"Raman Bhakhri, Rebecca Zoltoski, Julia Maida, Samantha Rivet, Jiani Lin, Tavleen Singh, Grace Sigler","doi":"10.1080/08164622.2025.2507392","DOIUrl":"https://doi.org/10.1080/08164622.2025.2507392","url":null,"abstract":"<p><strong>Clinical relevance: </strong>Nerf guns can lead to significant ocular injury. Understanding the incidence and types of complications that can result can lead to improved diagnoses, management, and prevention.</p><p><strong>Background: </strong>The intention of this study is to characterise the incidence, ocular findings, and specific visual outcomes associated with Nerf gun injuries at the Illinois College of Optometry, an academic optometric setting.</p><p><strong>Methods: </strong>A retrospective chart review of electronic medical records at the IEI was conducted from December 2017 to December 2022. Patient charts were identified using the search options in the electronic medical system. The following words and combinations were used during the electronic medical system search: Nerf, dart, bullet, foam, projectile, rubber. Charts were reviewed for accuracy.</p><p><strong>Results: </strong>Thirty-five patients were identified (21 females, 14 males) The average age of presentation was 24 years old (range 3-56 years). No patients were wearing protective eyewear. All injuries were unilateral. The follow-up period varied from 1 day to 1 month. Average entering best corrected visual acuity (BCVA) was 6/9, ranging between 6/6 and 6/45. All patients eventually returned to 6/6. Twenty-one patients (60%) were diagnosed with traumatic anterior uveitis. All 21 patients were treated with a topical steroid. All patients were dilated at the initial visit and at the follow-up visit. There were no findings in the intermediate and posterior segments of the eye secondary to nerf gun injuries.</p><p><strong>Conclusion: </strong>This current study specifically focuses on Nerf gun-related ocular injuries and their definite visual outcomes in a larger study population and period in an optometric setting. Most injuries are limited to the anterior segment with limited to no visual sequalae. Poorer visual outcomes are still possible and therefore proper safety eyewear, safe play, and safe distancing when using Nerf gun-type projectiles is recommended.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-4"},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined central retinal vein and cilioretinal artery occlusion with anterior ischaemic optic neuropathy in a haemodialysis patient.","authors":"Kemal Örnek, Özkan Kocamış, Sezin Seyitoğlu","doi":"10.1080/08164622.2025.2505569","DOIUrl":"https://doi.org/10.1080/08164622.2025.2505569","url":null,"abstract":"","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-2"},"PeriodicalIF":1.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azadeh Tavakoli, Judith Flanagan, Eric Papas, Maria Markoulli
{"title":"The impact of probiotics and prebiotics on ocular and systemic inflammation in dry eye disease: a double-masked, randomised controlled trial.","authors":"Azadeh Tavakoli, Judith Flanagan, Eric Papas, Maria Markoulli","doi":"10.1080/08164622.2025.2502529","DOIUrl":"https://doi.org/10.1080/08164622.2025.2502529","url":null,"abstract":"<p><strong>Clinical relevance: </strong>The management of dry eye disease remains a challenge due to its multifactorial nature and the involvement of chronic inflammation. Exploring the connection between gut health and eye inflammation is essential for developing more effective, holistic treatment strategies.</p><p><strong>Background: </strong>Dry eye disease is considered to have an inflammatory component. The gut microbiome plays an important role in the regulation of low-grade chronic inflammation in different parts of the body including the eye. Probiotics and prebiotics are recognised for their beneficial effects on gut health and have been previously reported to alleviate dry eye symptoms. This study aimed to further investigate the impact of these supplements on tear and blood serum inflammatory biomarkers.</p><p><strong>Methods: </strong>In this double-masked, randomised trial (registration number ACTRN12624000444583), 41 dry eye participants received either the probiotic and prebiotic supplements (treatment group, <i>n</i> = 23), or their respective placebos (control group, <i>n</i> = 18), for a duration of four months. The participants were followed up at one month and four months, and again one month after treatment cessation. Tear levels of inflammatory markers matrix metalloproteinase-9 (MMP-9) and tissue inhibitors of metalloproteinase-1 (TIMP-1), and serum C-reactive protein levels were determined. The MMP-9:TIMP-1 ratio also was calculated.</p><p><strong>Results: </strong>No significant changes in MMP-9, TIMP-1, or C-reactive protein levels were observed in either group during treatment (<i>p</i> > 0.05). Post-treatment, MMP-9 levels rose in the treatment group (<i>p</i> < 0.05), and MMP-9:TIMP-1 ratios increased in both groups (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>No significant changes were found in the examined biomarkers in either group during the intervention. The apparent post-treatment rise in these markers requires further investigation, particularly in light of reported associations between MMP-9, inflammation, and ocular discomfort.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lijuan Wang, Yee Ling Wong, Björn Drobe, Xiaoqian Wang
{"title":"Effectiveness of spectacle lenses with highly aspherical lenslets in slowing axial elongation among non-myopic children.","authors":"Lijuan Wang, Yee Ling Wong, Björn Drobe, Xiaoqian Wang","doi":"10.1080/08164622.2025.2502527","DOIUrl":"https://doi.org/10.1080/08164622.2025.2502527","url":null,"abstract":"<p><strong>Clinical relevance: </strong>Spectacle lenses with aspherical lenslets are effective in controlling axial elongation and slowing myopia progression in children with myopia, and its effectiveness may extend to children at risk of developing myopia.</p><p><strong>Background: </strong>This study aims to examine the effectiveness of plano highly aspherical lenslets (HAL) spectacle lenses in slowing down axial elongation and spherical equivalent refraction (SER) progression among non-myopic children, using retrospective data records.</p><p><strong>Methods: </strong>This retrospective study included data from medical records from an eye hospital network (Wellem Group) in Shanghai, China. Non-myopic children (non-cycloplegic SER between >-0.50 and ≤+0.75 D) aged 4-9 years, prescribed plano HAL lenses, were reviewed (<i>N</i> = 147). With available data prior to intervention, annualised changes in axial length and SER before and after wearing plano HAL lenses were computed. Effectiveness was evaluated with pre-treatment rates acting as controls, and differences in changes over time were calculated.</p><p><strong>Results: </strong>A total of 105 non-myopic children were prescribed plano HAL lenses and had both pre-treatment and post-treatment visits (≥6 months). The mean ±SD age, SER, and axial length was 6.8 ± 1.3 years, 0.22 ± 0.29 D, and 23.1 ± 0.7 mm, respectively. The mean ±SE axial length and SER pre-treatment change was +0.44 ± 0.01 mm/year and -0.28 ± 0.03 D/year, respectively. After treatment, the mean axial length and SER change were +0.13 ± 0.01 mm/year and +0.14 ± 0.03 D/year, respectively. The mean difference in axial length and SER change over time was significantly different at -0.31 ± 0.02 mm/year and 0.42 ± 0.06 D/year, respectively (both <i>p</i> < 0.001). Lens wearing time was significantly associated with difference in axial length change over time (R<sup>2</sup> = 0.19, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Plano HAL lenses are effective in slowing axial elongation and SER progression among non-myopic children aged 4-9 years, which can potentially help in delaying myopia onset.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-7"},"PeriodicalIF":1.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corneal microstructural changes, and nephropathy, in participants with diabetes mellitus with and without peripheral neuropathy: a systematic review and meta-analysis.","authors":"Himanshu Wadhwa, Stuti L Misra","doi":"10.1080/08164622.2025.2499601","DOIUrl":"https://doi.org/10.1080/08164622.2025.2499601","url":null,"abstract":"<p><p>The aim of this review is to evaluate corneal microstructural changes and nephropathy in participants with diabetic peripheral neuropathy (DPN+) and without (DPN-) in each of type 1 (T1DM) and type 2 diabetes (T2DM). A systematic review of primary studies was conducted that quantified corneal sub-basal nerve plexus parameters using laser scanning <i>in vivo</i> corneal confocal microscopy (CCM) and DPN+ in at least five humans with diabetes mellitus. CCM parameters examined were corneal nerve fibre density (NFD), nerve branch density (NBD) and nerve fibre length (NFL). Weighted mean difference (±standard error) is reported. Twenty-six studies were included in this meta-analysis (18 for T1DM, 14 for T2DM). This comprised 1,357 participants with T1DM (573,784; DPN+, DPN-), 1,119 with T2DM (598,521; DPN+, DPN-) and 1,032 non-diabetic controls. Compared to T2DM, T1DM participants had larger differences in NFD (8.54 ± 0.83 vs 3.61 ± 0.41), NBD (11.92 ± 1.93 vs 3.56 ± 1.03) and NFL (4.24 ± 0.41 vs 1.65 ± 0.18) between DPN+ and DPN- groups. T1DM participants also had larger differences than T2DM participants in NBD (-21.26 ± 2.90 vs -6.15 ± 1.69) and NFL (-4.25 ± 0.59 vs -2.65 ± 0.31) between DPN- and non-diabetic controls, but smaller, insignificant difference, in NFD (-5.93 ± 0.90 vs -6.39 ± 0.92). eGFR was significantly different between DPN+ and DPN- in T1DM (<i>p</i> < 0.00001) but not in T2DM (<i>p</i> = 0.46). When comparing DPN- to DPN+, ACR was reduced in T1DM (-2.72 ± 1.14) and T2DM (-20.85 ± 8.91). Corneal sub-basal nerve changes and glomerular nephropathy likely precede peripheral neuropathy in T1DM and T2DM, with greater corneal neuropathy in T1DM. The current evidence suggests that CCM may be useful for monitoring the progression of diabetic neuropathy and nephropathy.</p>","PeriodicalId":10214,"journal":{"name":"Clinical and Experimental Optometry","volume":" ","pages":"1-12"},"PeriodicalIF":1.7,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}