Circulation: Cardiovascular Imaging最新文献

{"title":"Exploration of ⁶⁸Ga-FAPI-04 PET/MR in Chronic Type B Aortic Dissection.","authors":"Chengkai Hu, Yuchong Zhang, Shouji Qiu, Zheyun Li, Weiguo Fu, Dengfeng Cheng, Hao Lai, Hui Tan, Hongcheng Shi, Lixin Wang","doi":"10.1161/CIRCIMAGING.124.017967","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017967","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017967"},"PeriodicalIF":6.5,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterogeneity of Myocardial Fibrosis Found in Twins With the MYBPC3 Variant Manifesting as Hypertrophic Cardiomyopathy.","authors":"Keyan Wang, Haiyu Li, Yong Zhang, Jie Zheng, Jingliang Cheng","doi":"10.1161/CIRCIMAGING.124.017837","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017837","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017837"},"PeriodicalIF":6.5,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Characterization of Myocardial Stiffness in Healthy Volunteers, Cardiac Amyloidosis, and Hypertrophic Cardiomyopathy: A Case-Control Study Using Multimodality Imaging.","authors":"Dominik C Benz, Ali Sadeghi, Pat G Rafter, Olivier F Clerc, Jocelyn Canseco Neri, Alexandra Taylor, Shilpa Vijayakumar, Carolyn Y Ho, Sarah A M Cuddy, Rodney H Falk, Sharmila Dorbala","doi":"10.1161/CIRCIMAGING.124.017475","DOIUrl":"10.1161/CIRCIMAGING.124.017475","url":null,"abstract":"<p><strong>Background: </strong>Noninvasive tools to measure myocardial stiffness are limited. Intrinsic cardiac elastography in echocardiography relates to myocardial stiffness by measuring the propagation of the myocardial stretch generated by atrial contraction. The aims of the present study were (1) to evaluate myocardial stiffness using intrinsic cardiac elastography in healthy volunteers versus those with myocardial diseases (ie, cardiac amyloidosis [CA] and hypertrophic cardiomyopathy) and (2) to identify key factors that affect myocardial stiffness.</p><p><strong>Methods: </strong>In this prospective study, myocardial stiffness was estimated in 54 participants, including 10 hypertrophic cardiomyopathy, 28 CA, and 16 healthy volunteers. Myocardial stiffness was assessed as intrinsic velocity propagation of myocardial stretch (iVP, m/s) measured by high frame rate echocardiography (ie, above 250 frames per second). Extracellular volume was quantified by cardiac magnetic resonance in 22 participants. Amyloid burden was quantified by cardiac amyloid activity in ^99mTc-labeled pyrophosphate single-photon emission computed tomography in 10 participants.</p><p><strong>Results: </strong>Myocardial stiffness was significantly higher in the CA cohort (median iVP, 2.6 m/s; interquartile range, 1.7-3.9 m/s) than in the hypertrophic cardiomyopathy cohort (median iVP, 1.4 m/s; interquartile range, 1.0-1.8 m/s; <i>P</i>=0.011). In patients with CA or hypertrophic cardiomyopathy, iVP was correlated with NT-proBNP (N-terminal pro-B-type natriuretic peptide) (ρ=0.498, <i>P</i>=0.003), extracellular volume (ρ=0.646, <i>P</i>=0.004), and cardiac amyloid activity (ρ=0.891, <i>P</i><0.001). In multivariate linear regression analysis, extracellular volume was independently associated with myocardial stiffness even after accounting for indexed left ventricular mass, global longitudinal strain, and E/e'. In healthy volunteers, normal myocardial stiffness was defined by the upper limit of normal of iVP at 1.7 m/s. Patients with CA and normal myocardial stiffness (iVP <1.7 m/s) were characterized by a low risk profile including lower NT-proBNP (<i>P</i>=0.034), lower troponin T (<i>P</i>=0.041), lower National Amyloidosis Center stage (<i>P</i>=0.031), smaller interstitial expansion (<i>P</i>=0.014), and smaller amyloid burden (<i>P</i>=0.056).</p><p><strong>Conclusions: </strong>Intrinsic cardiac elastography is a reliable noninvasive tool to measure myocardial stiffness. In this pilot study, it is related to imaging markers of interstitial expansion and amyloid burden.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017475"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11919568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Race- and Sex-Specific Age at Which Coronary Artery Calcium Becomes Detectable Among Young Adults.","authors":"Yvette A Yeboah-Kordieh, Ellen Boakye, Albert D Osei, Omar Dzaye, Zeina A Dardari, Joao A C Lima, Alan Rozanski, Daniel S Berman, Matthew J Budoff, Michael D Miedema, Khurram Nasir, John A Rumberger, Leslee J Shaw, David R Jacobs, Michael J Blaha","doi":"10.1161/CIRCIMAGING.124.016599","DOIUrl":"10.1161/CIRCIMAGING.124.016599","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery calcium (CAC) is an excellent predictor of atherosclerotic cardiovascular disease (ASCVD) risk. Limited data exist on the age at which CAC transitions to nonzero among young adults. We aimed to assess the prevalence of CAC by the number of ASCVD risk factors and use this data to model the race- and sex-specific ages at which young adults transition to a CAC >0.</p><p><strong>Methods: </strong>We included 17 285 participants aged 30 to 50 years from the CAC Consortium and the CARDIA (Coronary Artery Risk Development in Young Adults) study in this cross-sectional study. We estimated the burden of CAC by the number of ASCVD risk factors and used sex- and race-specific multivariable logistic regression models to predict the probability of CAC >0. From these, we estimated the age at CAC conversion from zero, using a minimum testing yield of 25%.</p><p><strong>Results: </strong>Of the 17 285 participants included in this study (mean age, 43.3±4.7years, 66.9% men, and 87.5% White), 30.1% had CAC >0. The probability of CAC >0 at each specified age and risk factor profile was higher among men than women and White compared with Black individuals. With 2 ASCVD risk factors, the estimated age at which CAC became detectable was 36.1 (35.1-36.9) years for White men, 41.9 (40.6-43.2) years for Black men, 47.6 (46.3-48.9) years for White women, and 51.6 (48.2-54.5) years for Black women.</p><p><strong>Conclusions: </strong>The age at which CAC becomes detectable in young adults varies substantially by race, sex, and the number of ASCVD risk factors. Earlier initiation of CAC scans may be indicated in select subgroups at greater risk of premature atherosclerosis.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e016599"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11919561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"T1 Mapping and Interstitial Fibrosis as a Marker for Heart Failure in Hypertrophic Cardiomyopathy.","authors":"Saad Ur Rahman, Ethan J Rowin","doi":"10.1161/CIRCIMAGING.124.017938","DOIUrl":"10.1161/CIRCIMAGING.124.017938","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017938"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thin Disguise: Workup of a Left Atrial Appendage Anomaly.","authors":"Robyn Bryde, B Robbie Williams, Matthew W Martinez","doi":"10.1161/CIRCIMAGING.124.017067","DOIUrl":"10.1161/CIRCIMAGING.124.017067","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017067"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can We Make the Next Step in Precision Risk Stratification of Dilated Cardiomyopathy?","authors":"Viren Ahluwalia, Brian P Halliday","doi":"10.1161/CIRCIMAGING.125.018057","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018057","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":"18 3","pages":"e018057"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Case Against Race-Based Coronary Artery Calcium Screening.","authors":"Shoa L Clarke","doi":"10.1161/CIRCIMAGING.124.017875","DOIUrl":"10.1161/CIRCIMAGING.124.017875","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017875"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of Myocardial T1 Mapping for Predicting Adverse Events in Hypertrophic Cardiomyopathy.","authors":"Jie Wang, Jinquan Zhang, Wei Liu, Lutong Pu, Weitang Qi, Yuanwei Xu, Ke Wan, Georgios V Gkoutos, Yuchi Han, Yucheng Chen","doi":"10.1161/CIRCIMAGING.124.017174","DOIUrl":"10.1161/CIRCIMAGING.124.017174","url":null,"abstract":"<p><strong>Background: </strong>In patients with hypertrophic cardiomyopathy, the prognostic value of myocardial T1 and extracellular volume fraction for adverse cardiovascular events has not been well defined.</p><p><strong>Methods: </strong>A total of 663 consecutive participants with hypertrophic cardiomyopathy who underwent 3T cardiovascular magnetic resonance were recruited. The follow-up end points included heart failure (HF)-related death, HF hospitalization, and sudden cardiac death or aborted sudden cardiac death.</p><p><strong>Results: </strong>On Cox proportional hazards regression multivariable analyses, global native T1 excluding late gadolinium enhancement areas (hazard ratio [HR], 1.04 [95% CI, 0.99-1.09]; <i>P</i>=0.094) and global extracellular volume fraction excluding late gadolinium enhancement (HR, 1.02 [95% CI, 0.95-1.10]; <i>P</i>=0.565) were not associated with sudden cardiac death. Conversely, global native T1 (HR, 1.08 per 10 ms increase [95% CI, 1.02-1.16], <i>P</i>=0.014; HR, 1.05 per 10 ms increase [95% CI, 1.01-1.09]; <i>P</i>=0.009) and global extracellular volume fraction (HR, 1.23 per 1% increase [95% CI, 1.11-1.36], <i>P</i><0.001; HR, 1.10 per 1% increase [95% CI, 1.04-1.16]; <i>P</i><0.001) were independently associated with HF-related death and the composite end point of HF-related death or HF hospitalization in multivariable Cox models, respectively.</p><p><strong>Conclusions: </strong>In this study of patients with hypertrophic cardiomyopathy, we found global native T1 and global extracellular volume fraction (excluding late gadolinium enhancement) to be both independently associated with HF-related events, but not sudden cardiac death in multivariable analysis. These findings are hypothesis-generating and will require external validation in larger cohorts.</p><p><strong>Registration: </strong>URL: https://www.chictr.org.cn; Unique identifier: ChiCTR1900024094.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017174"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single Meandering Right Pulmonary Vein With Potential Systemic Arterial Fistula: Serial Cardiac MRI Assessment With 4D Flow Characterization.","authors":"Michael DiMaria, Adam Dorfman, Sowmya Balasubramanian, Jimmy Lu, Prachi Agarwal, Swati Mody, Aparna Joshi, Anil Attili","doi":"10.1161/CIRCIMAGING.124.017147","DOIUrl":"10.1161/CIRCIMAGING.124.017147","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017147"},"PeriodicalIF":6.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}