Circulation: Cardiovascular Imaging最新文献

{"title":"Prognostic Value of Coronary Flow Capacity by ⁸²Rb PET in Patients With Suspected Coronary Artery Disease and Normal Myocardial Perfusion at Semiquantitative Imaging Analysis.","authors":"Emilia Zampella, Roberta Assante, Adriana D'Antonio, Teresa Mannarino, Valeria Gaudieri, Carmela Nappi, Parthiban Arumugam, Mariarosaria Panico, Pietro Buongiorno, Mario Petretta, Alberto Cuocolo, Wanda Acampa","doi":"10.1161/CIRCIMAGING.124.016815","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.016815","url":null,"abstract":"<p><strong>Background: </strong>Coronary flow capacity (CFC) is a measure that integrates hyperemic myocardial blood flow and myocardial flow reserve to quantify the pathophysiological impact of coronary artery disease on vasodilator capacity. We assessed the prognostic value of CFC derived from ⁸²Rb positron emission tomography/computed tomography in patients with suspected coronary artery disease and normal myocardial perfusion imaging.</p><p><strong>Methods: </strong>We studied 1967 patients with suspected coronary artery disease and normal myocardial perfusion at the semiquantitative analysis of stress/rest cardiac ⁸²Rb positron emission tomography/computed tomography imaging. Coronary artery calcium scores were calculated and categorized into 3 groups: 0, 0.1 to 99.9, and ≥100. Patients were classified as having myocardial steal, severely reduced CFC, moderately reduced CFC, mildly reduced CFC, minimally reduced CFC, or normal flow using previously defined thresholds. The outcome end points were myocardial infarction and cardiac death, whichever occurred first.</p><p><strong>Results: </strong>During a mean time of 41±27 months, 49 events occurred (2.5% cumulative event rate, with an annualized event rate of 0.5% person-years). At multivariable Cox analysis, coronary artery calcium score categories and impaired CFC resulted as independent predictors of events (both <i>P</i><0.001). The annualized event rate was higher in patients with impaired CFC compared with those with normal CFC (<i>P</i><0.05). Kaplan-Meier analysis showed that patients with impaired CFC were at the highest risk of events.</p><p><strong>Conclusions: </strong>In patients with suspected coronary artery disease and normal myocardial perfusion, impaired CFC is associated with a higher risk of cardiac events. Evaluating CFC can help identify patients' candidates for additional therapies to prevent future events.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single Meandering Right Pulmonary Vein With Potential Systemic Arterial Fistula: Serial Cardiac MRI Assessment With 4D Flow Characterization.","authors":"Michael DiMaria, Adam Dorfman, Sowmya Balasubramanian, Jimmy Lu, Prachi Agarwal, Swati Mody, Aparna Joshi, Anil Attili","doi":"10.1161/CIRCIMAGING.124.017147","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017147","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transitions From Basic Experimental to Clinical Coronary Pathophysiology for Guiding Chronic CAD Management.","authors":"K Lance Gould, Nils P Johnson","doi":"10.1161/CIRCIMAGING.124.017530","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017530","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thin Disguise: Workup of a Left Atrial Appendage Anomaly.","authors":"Robyn Bryde, B Robbie Williams, Matthew W Martinez","doi":"10.1161/CIRCIMAGING.124.017067","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017067","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Coronary Artery Assessment and Myocardial Late Enhancement Imaging With Photon-Counting Detector CT: Visualizing the Invisible.","authors":"Marie-Julie D K Lemmens, Samuel Heuts, Elham Bidar, Joachim E Wildberger, Casper Mihl, Martijn W Smulders","doi":"10.1161/CIRCIMAGING.124.017238","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017238","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platypnea-Orthodeoxia Syndrome After Esophageal Dilation in a Patient With a Dilated Ascending Aorta.","authors":"Matthew B Saunders, Matthew S Michaleski, Jeffrey Yim, Miles Marchand, John Jue, David A Wood, Christina L Luong, Michael Y C Tsang, Teresa S M Tsang, Darwin F Yeung","doi":"10.1161/CIRCIMAGING.124.016887","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.016887","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sudden Cardiac Arrest With Acute Myocardial Infarction Due to Myocardial Bridging and Hypertrophic Cardiomyopathy.","authors":"Yi-Ching Liu, Wei-Chung Tsai, Shu-Chien Huang, Min-Fang Chao, Shuenn-Nan Chiu, Yen-Hsien Wu, Shih-Hsing Lo, I-Chen Chen, Zen-Kong Dai, Jong-Hau Hsu","doi":"10.1161/CIRCIMAGING.124.016993","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.016993","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraindividual Comparison of Ultrahigh-Spatial-Resolution Photon-Counting Detector CT and Energy-Integrating Detector CT for Coronary Stenosis Measurement.","authors":"Milán Vecsey-Nagy, Giuseppe Tremamunno, U Joseph Schoepf, Chiara Gnasso, Emese Zsarnóczay, Nicola Fink, Dmitrij Kravchenko, Moritz C Halfmann, Gerald S Laux, Jim O'Doherty, Bálint Szilveszter, Pál Maurovich-Horvat, Ismail Mikdat Kabakus, Pal Spruill Suranyi, Akos Varga-Szemes, Tilman Emrich","doi":"10.1161/CIRCIMAGING.124.017112","DOIUrl":"10.1161/CIRCIMAGING.124.017112","url":null,"abstract":"<p><strong>Background: </strong>A recent simulation study proposed that stenosis measurements on coronary computed tomography (CT) angiography are influenced by the improved spatial resolution of photon-counting detector (PCD)-CT. The aim of the current study was to evaluate the impact of ultrahigh-spatial-resolution (UHR) on coronary stenosis measurements and Coronary Artery Disease Reporting and Data System (CAD-RADS) reclassification rates in patients undergoing coronary CT angiography on both PCD-CT and energy-integrating detector (EID)-CT and to compare measurements against quantitative coronary angiography.</p><p><strong>Methods: </strong>Patients with coronary calcification on EID-CT (collimation, 192×0.6 mm) were prospectively enrolled for a research coronary CT angiography with UHR PCD-CT (collimation, 120×0.2 mm) within 30 days (between April 1, 2023 and January 31, 2024). PCD-CT was acquired with the same or lower CT dose index and equivalent contrast media volume as EID-CT. Percentage diameter stenosis (PDS) for calcified, partially calcified, and noncalcified lesions were compared between scanners. Patient-level reclassification rates for CAD-RADS were evaluated. The accuracy of PDS measurements was validated against quantitative coronary angiography in patients who underwent invasive coronary angiography.</p><p><strong>Results: </strong>In total, PDS of 278 plaques were quantified in 49 patients (calcified, 202; partially calcified, 51; noncalcified, 25). PCD-CT-based PDS values were lower than EID-CT measurements for calcified (45.1±20.7 versus 54.6±19.2%; <i>P</i><0.001) and partially calcified plaques (44.3±19.6 versus 54.9±20.0%; <i>P</i><0.001), without significant differences for noncalcified lesions (39.1±15.2 versus 39.0±16.0%; <i>P</i>=0.98). The reduction in stenosis degrees led to a 49.0% (24/49) reclassification rate to a lower CAD-RADS with PCD-CT. In a subset of 12 patients with 56 lesions, UHR-based PDS values showed higher agreement with quantitative coronary angiography (mean difference, 7.3%; limits of agreement, -10.7%/25.2%) than EID-CT measurements (mean difference, 17.4%; limits of agreement, -6.9%/41.7%).</p><p><strong>Conclusions: </strong>Compared with conventional EID-CT, UHR PCD-CT results in lower PDS values and more accurate stenosis measurements in coronary plaques with calcified components and leads to a substantial Coronary Artery Disease Reporting and Data System reclassification rate in 49.0% of patients.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Plaque Characteristics in Patients With Chronic Kidney Failure: Impact on Cardiovascular Events and Mortality.","authors":"Jonathan Nørtoft Dahl, Marie B Nielsen, Laust D Rasmussen, Per Ivarsen, Michelle C Williams, My Hanna Sofia Svensson, Henrik Birn, Morten Bøttcher, Simon Winther","doi":"10.1161/CIRCIMAGING.124.017066","DOIUrl":"10.1161/CIRCIMAGING.124.017066","url":null,"abstract":"<p><strong>Background: </strong>In patients with coronary artery disease, coronary plaques with high-risk features and low-attenuation plaque burden are independent measures associated with major adverse cardiovascular events (MACEs). Patients with chronic kidney failure may have different coronary artery disease characteristics. The aim was to assess the association of coronary plaque characteristics and coronary artery disease extent with MACE and all-cause mortality in patients with chronic kidney failure.</p><p><strong>Methods: </strong>Potential kidney transplant candidates who underwent coronary computed tomography angiography as part of the cardiac screening program before kidney transplantation were included. We evaluated high-risk plaques and diameter stenosis semiqualitatively and quantified coronary artery calcium score and plaque burden (percentage atheroma volume).</p><p><strong>Results: </strong>In 484 patients with chronic kidney failure and few or no symptoms of coronary artery disease (mean age, 53±12 years; 62% men; 32% on dialysis), 56 (12%) patients suffered MACE and 69 (14%) patients died during a median follow-up of 4.9 years. High-risk plaques were present in 39 (70%) patients with MACE. Median calcified plaque burden was 3.7% in patients with MACE versus 0.2% in patients without MACE. The median low-attenuation plaque burden was 0.3% versus 0.03%, respectively. In semiqualitative analyses, the presence of high-risk plaque and a higher coronary artery calcium score were associated with increased risk of MACE (hazard ratio (HR), 2.0 [95% CI, 1.0-3.7]; <i>P</i>=0.040; HR, 1.2 [95% CI, 1.0-1.3]; <i>P</i>=0.014), respectively. Neither were associated with all-cause mortality. In quantified analysis, increasing levels of both calcified and low-attenuation plaque burdens were associated with risk of MACE (HR, 2.6 [95% CI, 1.8-3.7]; <i>P</i><0.001; HR, 2.6 [95% CI, 1.5-4.5]; <i>P</i>=0.001 [per variable doubling, respectively]) and all-cause mortality (HR, 1.6 [95% CI, 1.2-2.1]; <i>P</i>=0.002; HR, 1.8 [95% CI, 1.1-3.0]; <i>P</i>=0.028, respectively).</p><p><strong>Conclusions: </strong>In patients with chronic kidney failure, calcified and low-attenuation plaque burdens were independently associated with MACE and all-cause mortality, while high-risk plaques and coronary artery calcium score were only associated with MACE.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT01344434.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrafast Myocardial Contrast Echocardiography for the Assessment of Coronary Artery Disease: First In-Human Study.","authors":"Lasha Gvinianidze, Matthieu Toulemonde, Reinette Hampson, Biao Huang, Gabriel Bioh, Leigh-Ann Wakefield, Ashish Patel, Kiruba Rajan, Meng-Xing Tang, Roxy Senior","doi":"10.1161/CIRCIMAGING.124.017267","DOIUrl":"10.1161/CIRCIMAGING.124.017267","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}