Circulation: Cardiovascular Imaging最新文献

{"title":"PNPLA2 Mutation-Associated Cardiomyopathy Mimicking Dilated Cardiomyopathy: A Case Report.","authors":"Keyan Wang, Jie Zheng, Yong Zhang","doi":"10.1161/CIRCIMAGING.125.018597","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018597","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018597"},"PeriodicalIF":7.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortitis in Disguise: Cardiomyopathy in a Child With Takayasu Arteritis.","authors":"Liwei Yu, Amir B Orandi, Christian Hanna, Talha Niaz","doi":"10.1161/CIRCIMAGING.125.018497","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018497","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018497"},"PeriodicalIF":7.0,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platypnea-Orthodeoxia Syndrome After Transcatheter Aortic Valve Implantation.","authors":"Ling-Na Wong, Hei-Tung Chan, Tsz-Ho Chan, Wang-Hei Hui, Leo Kar-Lok Lai, Kevin Ka-Ho Kam, Simon Chi-Ying Chow, Alex Pui-Wai Lee, Kent Chak-Yu So","doi":"10.1161/CIRCIMAGING.125.018495","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018495","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018495"},"PeriodicalIF":7.0,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Cardiovascular Events Using Fully Automated Global Longitudinal and Circumferential Strain in Patients Undergoing Stress CMR.","authors":"Andreea Sorina Afana, Jérôme Garot, Suzanne Duhamel, Thomas Hovasse, Stéphane Champagne, Thierry Unterseeh, Philippe Garot, Mariama Akodad, Teodora Chitiboi, Puneet Sharma, Athira Jacob, Trecy Gonçalves, Jeremy Florence, Alexandre Unger, Francesca Sanguineti, Sebastian Militaru, Théo Pezel, Solenn Toupin","doi":"10.1161/CIRCIMAGING.125.018350","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018350","url":null,"abstract":"<p><strong>Background: </strong>Stress perfusion cardiovascular magnetic resonance (CMR) is widely used to detect myocardial ischemia, mostly through visual assessment. Recent studies suggest that strain imaging at rest and during stress can also help in prognostic stratification. However, the additional prognostic value of combining both rest and stress strain imaging has not been fully established. This study examined the incremental benefit of combining these strain measures with traditional risk prognosticators and CMR findings to predict major adverse clinical events (MACE) in a cohort of consecutive patients referred for stress CMR.</p><p><strong>Methods: </strong>This retrospective, single-center observational study included all consecutive patients with known or suspected coronary artery disease referred for stress CMR between 2016 and 2018. Fully automated machine learning was used to obtain global longitudinal strain at rest (rest-GLS) and global circumferential strain at stress (stress-GCS). The primary outcome was MACE, including cardiovascular death or hospitalization for heart failure. Cox models were used to assess the incremental prognostic value of combining these strain features with traditional prognosticators.</p><p><strong>Results: </strong>Of 2778 patients (age 65±12 years, 68% male), 96% had feasible, fully automated rest-GLS and stress-GCS measurements. After a median follow-up of 5.2 (4.8-5.5) years, 316 (11.1%) patients experienced MACE. After adjustment for traditional prognosticators, both rest-GLS (hazard ratio, 1.09 [95% CI, 1.05-1.13]; <i>P</i><0.001) and stress-GCS (hazard ratio, 1.08 [95% CI, 1.03-1.12]; <i>P</i><0.001) were independently associated with MACE. The best cutoffs for MACE prediction were >-10% for rest-GLS and stress-GCS, with a C-index improvement of 0.02, continuous net reclassification improvement of 15.6%, and integrative discrimination index of 2.2% (all <i>P</i><0.001).</p><p><strong>Conclusions: </strong>The combination of rest-GLS and stress-GCS, with a cutoff of >-10% provided an incremental prognostic value over and above traditional prognosticators, including CMR parameters, for predicting MACE in patients undergoing stress CMR.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018350"},"PeriodicalIF":7.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Lesion Visualization Following Interventional CMR Flutter Ablation Using PATRIOT CMR Imaging.","authors":"Luuk H G A Hopman, Nikki van Pouderoijen, Michiel J B Kemme, Raschel van Luijk, Pranav Bhagirath, Cornelis Allaart, Marco J W Gotte","doi":"10.1161/CIRCIMAGING.125.018540","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018540","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018540"},"PeriodicalIF":7.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broken Heart Does Not Forget: Persistent Microvascular Dysfunction in Takotsubo Syndrome.","authors":"Yasmeen Golzar, Rami Doukky","doi":"10.1161/CIRCIMAGING.125.018881","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018881","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018881"},"PeriodicalIF":7.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Microvascular Dysfunction and Incomplete Recovery in Takotsubo Syndrome: Insights From Serial PET Imaging.","authors":"Yoshito Kadoya, Aun Yeong Chong, Gary R Small, Benjamin Chow, Robert deKemp, Terrence D Ruddy, Rob Beanlands, Andrew M Crean","doi":"10.1161/CIRCIMAGING.125.018266","DOIUrl":"10.1161/CIRCIMAGING.125.018266","url":null,"abstract":"<p><strong>Background: </strong>The proposed cause of Takotsubo syndrome (TTS) includes coronary microvascular dysfunction. This study aimed to investigate coronary microvascular dysfunction and its recovery in patients with TTS using serial positron emission tomography myocardial perfusion imaging.</p><p><strong>Methods: </strong>Patients with TTS who underwent cardiac positron emission tomography within 30 days of admission and at 6-month follow-up (May 2017-June 2023) were analyzed. Changes in positron emission tomography parameters, including extent of myocardial perfusion abnormality, left ventricular function, rest and stress myocardial blood flow (MBF), myocardial flow reserve, and coronary vascular resistance (CVR), were assessed from baseline to follow-up. In apical TTS, segmental analyses (basal, mid, distal segments, and apex) and intersegment differences were evaluated.</p><p><strong>Results: </strong>Of 130 patients screened, 62 patients (median age, 70 years, 97% female) were included. After a median follow-up of 178 (121-282) days, global rest and stress MBF, myocardial flow reserve, and CVR significantly improved at follow-up (0.81-0.89 mL/min per gram, <i>P</i>=0.004; 1.56-2.61 mL/min per gram, <i>P</i><0.001; 1.96-2.65, <i>P</i><0.001; 52.0-36.2 mm Hg·min·g/mL, <i>P</i><0.001, respectively). Among 53 patients with apical TTS, improvements in stress MBF, myocardial flow reserve, and CVR were noted in all myocardial segments (all <i>P</i><0.001), including the basal segment; however, persistent MBF and CVR abnormalities were identified in the distal segment and apex, despite full recovery of left ventricular function.</p><p><strong>Conclusions: </strong>Patients who underwent serial positron emission tomography perfusion imaging for TTS demonstrated reversible reductions in rest and stress MBF, myocardial flow reserve, and increases in CVR, suggestive of TTS-related coronary microvascular dysfunction and subsequent subtotal recovery. Coronary microvascular dysfunction extended beyond regions of wall motion abnormalities, and regional coronary flow abnormalities persisted in the medium term even after recovery of left ventricular function.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018266"},"PeriodicalIF":7.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Representation of Older Adults and Women in Randomized Trials of Noninvasive Imaging for Chest Pain.","authors":"Phillip Lim, Tansu Eris, Leslee J Shaw, Laura Gelfman, Annetine Gelijns, Alan Moskowitz, Emilia Bagiella, Fay A Lin, Deepak L Bhatt, Gregg Stone, R Sean Morrison, David Cohen, Michael Nanna, Karen Alexander, Krishna K Patel","doi":"10.1161/CIRCIMAGING.125.018295","DOIUrl":"10.1161/CIRCIMAGING.125.018295","url":null,"abstract":"<p><strong>Background: </strong>Noninvasive imaging is widely used both for initial diagnosis and to guide management of ischemic heart disease. Older adults and women with ischemic heart disease may have different responses to imaging as well as to treatments and outcomes that follow compared with younger adults and men. We aimed to study the representation of older adults and women in randomized controlled trials of noninvasive imaging among patients with acute and stable chest pain.</p><p><strong>Methods: </strong>We conducted a systematic search across PubMed, ClinicalTrials.gov, and guidelines to identify randomized controlled trials of noninvasive imaging-guided diagnosis and management for ischemic heart disease that were published between 2002 and 2023. Participation-to-prevalence ratio (PPR) was estimated for women and age subgroups of <65, 65 to 74, ≥75 years. PPR of <0.8, 0.8 to 1.2, and >1.2 indicated underrepresentation, appropriate representation, and overrepresentation, respectively.</p><p><strong>Results: </strong>Among 53 randomized controlled trials, age and sex breakdown were available in 21 (n=35 503) and 53 (n=55 893) trials, respectively. The median age across all trials was 57.4 years (interquartile range, 55.0-60.2). Participants aged <65 years were overrepresented with a median PPR of 2.13 (interquartile range, 1.73-2.43), whereas those aged 65 to 74 years and ≥75 years were underrepresented with median PPRs of 0.74 (interquartile range, 0.56-0.83) and 0.21 (interquartile range, 0.11-0.33), respectively. Women were adequately represented with a median PPR of 1.2 (1.06-1.32).</p><p><strong>Conclusions: </strong>Although women were appropriately represented, adults ≥65 years, especially those ≥75 years, were underrepresented in these trials. Future randomized controlled trials on chest pain imaging should target enrollment of older adults to ensure generalizability of results to this population.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018295"},"PeriodicalIF":7.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory Myofibroblastic Tumor Mimicking Pulmonary Artery Sarcoma and Causing Pulmonary Artery Obstruction: A Rare Case Report.","authors":"Pingping Han, Yanfen Shi, Huan Li, Liping Fu","doi":"10.1161/CIRCIMAGING.124.017658","DOIUrl":"10.1161/CIRCIMAGING.124.017658","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017658"},"PeriodicalIF":7.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is It Time to Retire LVEF as a Predictive Metric in HFpEF?","authors":"Eddy Barasch, Omar K Khalique","doi":"10.1161/CIRCIMAGING.125.018785","DOIUrl":"10.1161/CIRCIMAGING.125.018785","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018785"},"PeriodicalIF":7.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}