{"title":"Correction to: Mahmod et al, \"Differentiating Left Ventricular Remodeling in Aortic Stenosis From Systemic Hypertension\".","authors":"","doi":"10.1161/HCI.0000000000000085","DOIUrl":"https://doi.org/10.1161/HCI.0000000000000085","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raffaello Ditaranto, Chiara Chiti, Agnese Milandri, Francesco Lai, Luigi Lovato, Maddalena Graziosi, Francesca Graziani, Maurizio Pieroni, Francesco Cappelli, Giuseppe Limongelli, Iacopo Olivotto, Elena Biagini
{"title":"Atypical Subendocardial Late Gadolinium Enhancement in Anderson-Fabry Cardiomyopathy.","authors":"Raffaello Ditaranto, Chiara Chiti, Agnese Milandri, Francesco Lai, Luigi Lovato, Maddalena Graziosi, Francesca Graziani, Maurizio Pieroni, Francesco Cappelli, Giuseppe Limongelli, Iacopo Olivotto, Elena Biagini","doi":"10.1161/CIRCIMAGING.124.016865","DOIUrl":"10.1161/CIRCIMAGING.124.016865","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shruti S Joshi, Jolien Geers, Alessia Gimelli, Fabien Hyafil, Gilbert Habib, Paola Erba, Olivier Gheysens, Andor W J M Glaudemans, David E Newby, Riemer H J A Slart, Marc R Dweck
{"title":"Current and Emerging Radiotracers in Molecular Cardiovascular Imaging.","authors":"Shruti S Joshi, Jolien Geers, Alessia Gimelli, Fabien Hyafil, Gilbert Habib, Paola Erba, Olivier Gheysens, Andor W J M Glaudemans, David E Newby, Riemer H J A Slart, Marc R Dweck","doi":"10.1161/CIRCIMAGING.123.016323","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.123.016323","url":null,"abstract":"<p><p>Cardiovascular imaging has rapidly advanced over the past decades. Traditional imaging techniques such as echocardiography, computed tomography, and cardiovascular magnetic resonance are essential for assessing the structural and functional aspects of the cardiovascular system but often fall short in providing direct insights into disease activity. This gap is increasingly being bridged by molecular nuclear imaging techniques, including positron emission tomography and single-photon emission computed tomography, which enable the visualization of disease processes at the molecular and cellular levels. This review highlights the role of cardiovascular molecular imaging, emphasizing its current and potential applications in diagnosing and managing cardiovascular disease. With advancements in positron emission tomography scanners, novel radiotracers, and sophisticated imaging software, molecular imaging is set to play an essential role in precision medicine by enhancing our understanding of disease mechanisms, accelerating the development of targeted therapies, and facilitating personalized patient care.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert J H Miller, Nipun Manral, Andrew Lin, Aakash Shanbhag, Caroline Park, Jacek Kwiecinski, Aditya Killekar, Priscilla McElhinney, Hidenari Matsumoto, Aryabod Razipour, Kajetan Grodecki, Alan C Kwan, Donghee Han, Keiichiro Kuronuma, Guadalupe Flores Tomasino, Jolien Geers, Markus Goeller, Mohamed Marwan, Heidi Gransar, Balaji K Tamarappoo, Sebastien Cadet, Victor Y Cheng, Stephan Achenbach, Stephen J Nicholls, Dennis T Wong, Lu Chen, J Jane Cao, Daniel S Berman, Marc R Dweck, David E Newby, Michelle C Williams, Piotr J Slomka, Damini Dey
{"title":"Patient-Specific Myocardial Infarction Risk Thresholds From AI-Enabled Coronary Plaque Analysis.","authors":"Robert J H Miller, Nipun Manral, Andrew Lin, Aakash Shanbhag, Caroline Park, Jacek Kwiecinski, Aditya Killekar, Priscilla McElhinney, Hidenari Matsumoto, Aryabod Razipour, Kajetan Grodecki, Alan C Kwan, Donghee Han, Keiichiro Kuronuma, Guadalupe Flores Tomasino, Jolien Geers, Markus Goeller, Mohamed Marwan, Heidi Gransar, Balaji K Tamarappoo, Sebastien Cadet, Victor Y Cheng, Stephan Achenbach, Stephen J Nicholls, Dennis T Wong, Lu Chen, J Jane Cao, Daniel S Berman, Marc R Dweck, David E Newby, Michelle C Williams, Piotr J Slomka, Damini Dey","doi":"10.1161/CIRCIMAGING.124.016958","DOIUrl":"10.1161/CIRCIMAGING.124.016958","url":null,"abstract":"<p><strong>Background: </strong>Plaque quantification from coronary computed tomography angiography has emerged as a valuable predictor of cardiovascular risk. Deep learning can provide automated quantification of coronary plaque from computed tomography angiography. We determined per-patient age- and sex-specific distributions of deep learning-based plaque measurements and further evaluated their risk prediction for myocardial infarction in external samples.</p><p><strong>Methods: </strong>In this international, multicenter study of 2803 patients, a previously validated deep learning system was used to quantify coronary plaque from computed tomography angiography. Age- and sex-specific distributions of coronary plaque volume were determined from 956 patients undergoing computed tomography angiography for stable coronary artery disease from 5 cohorts. Multicenter external samples were used to evaluate associations between coronary plaque percentiles and myocardial infarction.</p><p><strong>Results: </strong>Quantitative deep learning plaque volumes increased with age and were higher in male patients. In the combined external sample (n=1847), patients in the ≥75th percentile of total plaque volume (unadjusted hazard ratio, 2.65 [95% CI, 1.47-4.78]; <i>P</i>=0.001) were at increased risk of myocardial infarction compared with patients below the 50th percentile. Similar relationships were seen for most plaque volumes and persisted in multivariable analyses adjusting for clinical characteristics, coronary artery calcium, stenosis, and plaque volume, with adjusted hazard ratios ranging from 2.38 to 2.50 for patients in the ≥75th percentile of total plaque volume.</p><p><strong>Conclusions: </strong>Per-patient age- and sex-specific distributions for deep learning-based coronary plaque volumes are strongly predictive of myocardial infarction, with the highest risk seen in patients with coronary plaque volumes in the ≥75th percentile.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anomalous Origin of Left Pulmonary Artery From the Left Carotid Artery With a Right Aortic Arch and Aberrant Left Subclavian Artery in a Neonate With DiGeorge Syndrome.","authors":"Naruhito Watanabe, Ashley Hapak, Teimour Nasirov","doi":"10.1161/CIRCIMAGING.124.016355","DOIUrl":"10.1161/CIRCIMAGING.124.016355","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
You-Jung Choi, Jah Yeon Choi, Jieun Lee, Byoung Geol Choi, Soohyung Park, Dong Oh Kang, Eun Jin Park, Ji Bak Kim, Seung-Young Roh, Cheol Ung Choi, Jin Won Kim, Eung Ju Kim, Seung-Woon Rha, Chang Gyu Park, Hwan Seok Yong, Man-Jong Baek, Jin Oh Na
{"title":"Prognostic Value of Pulmonary Artery Systolic Pressure in Severe Rheumatic Mitral Stenosis.","authors":"You-Jung Choi, Jah Yeon Choi, Jieun Lee, Byoung Geol Choi, Soohyung Park, Dong Oh Kang, Eun Jin Park, Ji Bak Kim, Seung-Young Roh, Cheol Ung Choi, Jin Won Kim, Eung Ju Kim, Seung-Woon Rha, Chang Gyu Park, Hwan Seok Yong, Man-Jong Baek, Jin Oh Na","doi":"10.1161/CIRCIMAGING.123.016302","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.123.016302","url":null,"abstract":"<p><strong>Background: </strong>Current guidelines recommend intervention for asymptomatic rheumatic mitral stenosis (MS) with mitral valve area ≤1.5 cm<sup>2</sup> based on indicators including pulmonary arterial systolic pressure (PASP) >50 mm Hg and new-onset atrial fibrillation; however, evidence supporting this is lacking.</p><p><strong>Methods: </strong>This single-center retrospective study included patients with rheumatic MS between 2006 and 2022. Pulmonary hypertension was evaluated by using echocardiography to estimate PASP. Primary outcomes were major adverse cardiovascular events (MACE), including all-cause mortality, hospitalization for heart failure, and arterial thromboembolic events for up to 5 years.</p><p><strong>Results: </strong>Overall, 287 patients with severe rheumatic MS were enrolled (mean age, 62.5±11.3 years; 74.6% women). During a median follow-up of 2.52 years, MACE occurred in 99 patients. There were no differences in echocardiographic parameters, such as the mean mitral valve pressure gradient, mitral valve area, and proportion of mitral valve area <1.0 cm<sup>2</sup>, between patients who developed primary outcomes and those who did not. Survival analysis showed a worse prognosis in patients with estimated PASP (ePASP) >50 mm Hg than in those with ePASP ≤50 mm Hg (log-rank <i>P</i><0.001); however, atrial fibrillation was not a significant prognostic indicator. As a continuous variable, ePASP (mm Hg) was a significant predictor of MACE (adjusted hazard ratio, 1.027 [95% CI, 1.011-1.042]; <i>P</i><0.001). Receiver operating characteristic analysis revealed an optimal ePASP threshold of >45 mm Hg, which was an independent predictor of MACE in patients with severe rheumatic MS (adjusted hazard ratio, 2.127 [95% CI, 1.424-3.177]; <i>P</i><0.001). Competing risk analysis considering mitral valve intervention as a competing risk showed similar results.</p><p><strong>Conclusions: </strong>Our study demonstrated the prognostic significance of ePASP, rather than atrial fibrillation, in relation to MACE among patients with severe rheumatic MS. Additionally, we proposed a lower ePASP threshold (>45 mm Hg) as a predictor of an unfavorable prognosis.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Jose Santa Ana-Bayona, Pavel Martinez-Dominguez, Oscar Perez-Orpinel, Enrique C Guerra, Nilda Espinola-Zavaleta
{"title":"Beyond the Usual Suspects: Myocardial Infarction Triggered by Coronary Vasculitis in a Young Patient With Systemic Lupus Erythematosus.","authors":"Maria Jose Santa Ana-Bayona, Pavel Martinez-Dominguez, Oscar Perez-Orpinel, Enrique C Guerra, Nilda Espinola-Zavaleta","doi":"10.1161/CIRCIMAGING.124.017009","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017009","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":6.5,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accelerated Pace of Atherosclerosis in Steatotic Liver Disease: Implications for Risk Stratification.","authors":"Andrei C Sposito","doi":"10.1161/circimaging.124.017376","DOIUrl":"https://doi.org/10.1161/circimaging.124.017376","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Paolisso et al, \"Cardiac Magnetic Resonance to Predict Cardiac Mass Malignancy: The CMR Mass Score\".","authors":"","doi":"10.1161/hci.0000000000000084","DOIUrl":"https://doi.org/10.1161/hci.0000000000000084","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}