Circulation: Cardiovascular Imaging最新文献

{"title":"Response to Letter Regarding Article, \"Progressive LV Dysfunction and Adverse Outcomes After Aortic Valve Replacement With Bioprosthetic Valves in Young Patients\".","authors":"Alexander C Egbe","doi":"10.1161/CIRCIMAGING.125.018560","DOIUrl":"10.1161/CIRCIMAGING.125.018560","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018560"},"PeriodicalIF":6.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac CT Versus Transesophageal Echocardiography Following Left Atrial Appendage Closure: A Systemic Review and Meta-Analysis.","authors":"Bryan E-Xin Tan, Faiz Baqai, Fernando Padilla, Nadeem Nimri, Jim W Cheung, Anupama Kottam, Hector M Medina","doi":"10.1161/CIRCIMAGING.125.018151","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018151","url":null,"abstract":"<p><strong>Background: </strong>In the landmark WATCHMAN trials, transesophageal echocardiography (TEE) was used to evaluate peri-device leak (PDL) and device-related thrombus (DRT) after percutaneous left atrial appendage closure (LAAC). We aimed to investigate the diagnostic utility of cardiac computed tomography angiography (CCTA) compared with TEE for post-LAAC device surveillance.</p><p><strong>Methods: </strong>We conducted a literature search of 5 electronic databases to identify studies that included patients who underwent both CCTA and TEE after LAAC. We performed a meta-analysis by pooling outcomes for residual leak (left atrial appendage patency), any PDL, large PDL (>5 mm), and DRT.</p><p><strong>Results: </strong>We included 17 cohort studies with 1313 patients who underwent both CCTA and TEE after LAAC. CCTA was associated with higher odds of detecting residual leak (58.8% versus 34.6%, odds ratio, 2.26 [95% CI, 1.48-3.44], <i>P</i>=0.0002; <i>I</i>²=73%; 15 studies, 975 patients; moderate certainty) and any PDL (51.6% versus 35.5%, odds ratio, 1.59 [95% CI, 1.01-2.51], <i>P</i>=0.04; <i>I</i>²=73%; 12 studies, 870 patients; moderate certainty) when compared with TEE. There were no significant differences in the detection rates of large PDL (>5 mm) between CCTA and TEE (2.8% versus 0.8%, odds ratio, 3.12 [95% CI, 0.73-13.36], <i>P</i>=0.13; <i>I</i>²=0%; 5 studies, 338 patients; moderate certainty). The incidence of DRT was low (1.7%), and the detection rate did not differ between the 2 modalities (1.7% versus 1.7%, odds ratio, 1.0 [95% CI, 0.41-2.42], <i>P</i>=1.0; <i>I</i>²=0%; 6 studies, 584 patients; high-certainty).</p><p><strong>Conclusions: </strong>Following LAAC, CCTA had higher odds of detecting residual leak and any PDL compared with TEE, whereas there were no significant differences in the detection of large PDL and DRT between the 2 modalities. The findings of this meta-analysis should provide reassurance to patients and clinicians who prefer CCTA over TEE after LAAC. While DRT and left atrial appendage patency with visible PDL are known to be associated with thromboembolism, the clinical significance of left atrial appendage patency without visible PDL is uncertain and warrants further investigation.</p><p><strong>Registration: </strong>URL: https://www.crd.york.ac.uk/PROSPERO/; Unique identifier: CRD42024578802.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018151"},"PeriodicalIF":6.5,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Clinical Utility of Fetal Cine CMR Using Deep Learning Super-Resolution.","authors":"Thomas M Vollbrecht, Christopher Hart, Christoph Katemann, Alexander Isaak, Marilia B Voigt, Claus C Pieper, Daniel Kuetting, Annegret Geipel, Brigitte Strizek, Julian A Luetkens","doi":"10.1161/CIRCIMAGING.125.018090","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018090","url":null,"abstract":"<p><strong>Background: </strong>Fetal cardiovascular magnetic resonance is an emerging tool for prenatal congenital heart disease assessment, but long acquisition times and fetal movements limit its clinical use. This study evaluates the clinical utility of deep learning super-resolution reconstructions for rapidly acquired, low-resolution fetal cardiovascular magnetic resonance.</p><p><strong>Methods: </strong>This prospective study included participants with fetal congenital heart disease undergoing fetal cardiovascular magnetic resonance in the third trimester of pregnancy, with axial cine images acquired at normal resolution and low resolution. Low-resolution cine data was subsequently reconstructed using a deep learning super-resolution framework (cine_DL). Acquisition times, apparent signal-to-noise ratio, contrast-to-noise ratio, and edge rise distance were assessed. Volumetry and functional analysis were performed. Qualitative image scores were rated on a 5-point Likert scale. Cardiovascular structures and pathological findings visible in cine_DL images only were assessed. Statistical analysis included the Student paired <i>t</i> test and the Wilcoxon test.</p><p><strong>Results: </strong>A total of 42 participants were included (median gestational age, 35.9 weeks [interquartile range (IQR), 35.1-36.4]). Cine_DL acquisition was faster than cine images acquired at normal resolution (134±9.6 s versus 252±8.8 s; <i>P</i><0.001). Quantitative image quality metrics and image quality scores for cine_DL were higher or comparable with those of cine images acquired at normal-resolution images (eg, fetal motion, 4.0 [IQR, 4.0-5.0] versus 4.0 [IQR, 3.0-4.0]; <i>P</i><0.001). Nonpatient-related artifacts (eg, backfolding) were more pronounced in Cine_DL compared with cine images acquired at normal-resolution images (4.0 [IQR, 4.0-5.0] versus 5.0 [IQR, 3.0-4.0]; <i>P</i><0.001). Volumetry and functional results were comparable. Cine_DL revealed additional structures in 10 of 42 fetuses (24%) and additional pathologies in 5 of 42 fetuses (12%), including partial anomalous pulmonary venous connection.</p><p><strong>Conclusions: </strong>Deep learning super-resolution reconstructions of low-resolution acquisitions shorten acquisition times and achieve diagnostic quality comparable with standard images, while being less sensitive to fetal bulk movements, leading to additional diagnostic findings. Therefore, deep learning super-resolution may improve the clinical utility of fetal cardiovascular magnetic resonance for accurate prenatal assessment of congenital heart disease.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018090"},"PeriodicalIF":6.5,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144494978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter by Sacoransky Regarding Article, \"Deep Learning-Derived Cardiac Chamber Volumes and Mass From PET/CT Attenuation Scans: Associations With Myocardial Flow Reserve and Heart Failure\".","authors":"Ethan Sacoransky","doi":"10.1161/CIRCIMAGING.125.018652","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018652","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018652"},"PeriodicalIF":6.5,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response by Murai et al to Letter Regarding Article, \"Impact of Post-PCI Lipid Core Burden Index on Angiographic and Clinical Outcomes: Insights From NIRS-IVUS\".","authors":"Woohyeun Kim, Hyungdon Kook, Yonggu Lee, Young-Hyo Lim","doi":"10.1161/CIRCIMAGING.125.018586","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018586","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018586"},"PeriodicalIF":6.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dark Side of Pericardial Effusions: What Shall We Keep in Mind.","authors":"Alexander Suchodolski, Rafał Skowronek, Jan Głowacki, Jerzy Nożyński, Paweł Ziora, Bogna Drozdzowska, Dariusz Lange, Mariola Szulik","doi":"10.1161/CIRCIMAGING.124.017747","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017747","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017747"},"PeriodicalIF":6.5,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Echocardiographic Probability of Pulmonary Hypertension on Prognosis and Outcomes Among Patients With Myeloproliferative Neoplasms.","authors":"Orly Leiva, Steven Soo, Nathaniel R Smilowitz, Harmony Reynolds, Binita Shah, Samuel Bernard, Joan How, Michelle Hyunju Lee, Gabriela Hobbs","doi":"10.1161/CIRCIMAGING.124.017986","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.124.017986","url":null,"abstract":"<p><strong>Background: </strong>Myeloproliferative neoplasms (MPN) are a group of chronic leukemias that are associated with pulmonary hypertension (PH), which has been associated with increased risk adverse outcomes. The echocardiographic characterization of PH in MPN has not been reported, and the prognostic significance of PH among patients with MPN remains unclear.</p><p><strong>Methods: </strong>Multicenter, retrospective cohort study of patients with MPN with ≥1 echocardiogram from 2010 to 2023. The echocardiographic probability of PH was determined according to the guidelines. The outcomes were hematologic progression and major adverse cardiovascular events. Exploratory analysis included outcomes among patients with right heart catheterization after the first echocardiogram, with PH defined as mean pulmonary artery pressure of >20 mm Hg. Multivariable Fine-Gray competing risk regression was used to estimate the subhazard ratio of hematologic progression and major adverse cardiovascular events.</p><p><strong>Results: </strong>Five hundred fifty-five patients were included and 237 (42.7%) had an intermediate or high probability of PH on echocardiography. Over a median follow-up period of 51.2 months (interquartile range, 29.5-79.8), it was observed that echocardiographic probability of PH was associated with increased risk of hematologic progression (adjusted subhazard ratio, 1.92 [95% CI, 1.09-3.39]) and major adverse cardiovascular events (adjusted subhazard ratio, 1.66 [95% CI, 1.04-2.66]) but not all-cause death (adjusted hazard ratio, 1.51 [95% CI, 0.98-2.32]). Among patients with right heart catheterization (n=61), PH was present in 51 (83.6%) of patients and was associated with a higher risk of hematologic progression (29.4% versus 0%; <i>P</i>=0.048).</p><p><strong>Conclusions: </strong>Among patients with MPN, echocardiographic probability of PH was associated with an increased risk of hematologic progression. Prospective studies are needed to assess the optimal use of echocardiography on MPN-specific prognostication.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e017986"},"PeriodicalIF":6.5,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter by Murai et al Regarding Article, \"Impact of Post-PCI Lipid Core Burden Index on Angiographic and Clinical Outcomes: Insights From NIRS-IVUS\".","authors":"Kota Murai, Yu Kataoka, Teruo Noguchi","doi":"10.1161/CIRCIMAGING.125.018568","DOIUrl":"https://doi.org/10.1161/CIRCIMAGING.125.018568","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018568"},"PeriodicalIF":6.5,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unfolding Evidence on Risk Stratification in Women Using Quantitative Atherosclerotic Plaque Measurements.","authors":"Leslee J Shaw, Fay Y Lin","doi":"10.1161/CIRCIMAGING.125.018438","DOIUrl":"10.1161/CIRCIMAGING.125.018438","url":null,"abstract":"","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018438"},"PeriodicalIF":6.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-Quantitative CT Coronary Plaque Features Associate With a Higher Relative Risk in Women: CONFIRM2 Registry.","authors":"Gudrun M Feuchtner, Pietro G Lacaita, Jeroen J Bax, Fatima Rodriguez, Rine Nakanishi, Gianluca Pontone, Saima Mushtaq, Ronny R Buechel, Christoph Gräni, Amit R Patel, Cristiane C Singulane, Andrew D Choi, Mouaz Al-Mallah, Daniele Andreini, Ronald P Karlsberg, Geoffrey Cho, Carlos E Rochitte, Mirvat Alasnag, Ashraf Hamdan, Filippo Cademartiri, Erica Maffei, Hugo Marques, Pedro M Gonçalves Pereira, Himanshu Gupta, Martin Hadamitzky, Omar Khalique, Dinesh Kalra, James D Mills, Nick S Nurmohamed, Paul Knaapen, Matthew Budoff, Kashif Shaikh, Enrico Martin, David M German, Maros Ferencik, Andrew C Oehler, Roderick Deaño, Prashant Nagpal, Marly Van Assen, Carlo Nicola De Cecco, Borek Foldyna, Jan Michael Brendel, Victor Y Cheng, Kelley Branch, Marcio Bittencourt, Sabha Bhatti, Venkateshwar Polsani, George Wesbey, Rhanderson Cardoso, Ron Blankstein, Augustin Delago, Amit Pursnani, Amro Alsaid, Stephen Bloom, Vasileios Kamperidis, Fabian Barbieri, Melissa Aquino, Ibrahim Danad, Alexander van Rosendael","doi":"10.1161/CIRCIMAGING.125.018235","DOIUrl":"10.1161/CIRCIMAGING.125.018235","url":null,"abstract":"<p><strong>Background: </strong>Coronary plaque features are imaging biomarkers of cardiovascular risk, but less is known about sex-specific patterns in their prognostic value. This study aimed to define sex differences in the coronary atherosclerotic phenotypes assessed by artificial intelligence-based quantitative computed tomography (AI-QCT) and the associated risk of major adverse cardiovascular events (MACEs).</p><p><strong>Methods: </strong>Global multicenter registry including symptomatic patients with suspicion of coronary artery disease referred for coronary computed tomography angiography. AI-QCT analyzed 16 coronary artery disease features. The primary end point was MACE defined as death, myocardial infarction, late revascularization, cerebrovascular events, unstable angina, and congestive heart failure.</p><p><strong>Results: </strong>Among 3551 patients (mean age, 59±12 years; 49.5% women), MACE occurred in 3.2% of women and 6.1% of men during an average follow-up of 4.8±2.2 years. The AI-QCT features total plaque volume, noncalcified plaque, calcified plaque, and percentage atheroma volume were significantly higher in men (<i>P</i><0.001), and high-risk plaques were more prevalent (9.2% versus 2.5%; <i>P</i><0.0001). Independent of age and cardiovascular risk factors, the AI-QCT-derived features of total plaque volume, noncalcified plaque, calcified plaque, and percentage atheroma volume conferred a higher relative risk of MACE in women than men. For every 50-mm³ increase in total plaque volume, relative risk increased by 17.7% (95% CI, 1.12-1.24) in women versus 5.3% (95% CI, 1.03-1.07) in men (<i>P</i>_interaction<0.001); for noncalcified plaque, relative risk increased by 27.1% (95% CI, 1.17-1.38) versus 11.6% (95% CI, 1.08-1.15; <i>P</i>_interaction=0.0015); and for calcified plaque, relative risk increased by 22.9% (95% CI, 1.14-1.33) versus 5.4% (95% CI, 1.01-1.10; <i>P</i>_interaction=0.0012), respectively. Similarly, for percentage atheroma volume, the risk was higher in women. The findings remained unchanged when restricted to a secondary composite end point (death and myocardial infarction).</p><p><strong>Conclusions: </strong>The AI-QCT plaque features, total plaque volume, noncalcified plaque, calcified plaque, and percentage atheroma volume, conferred a higher relative MACE risk in women and may prompt more aggressive antiatherosclerotic therapy and reinforced preventive interventions.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT04279496.</p>","PeriodicalId":10202,"journal":{"name":"Circulation: Cardiovascular Imaging","volume":" ","pages":"e018235"},"PeriodicalIF":6.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}