Acta medica (Hradec Kralove)最新文献

Two Hurt More Than One: Severe Hyponatraemia and Rhabdomyolysis as Presenting Features of Addison's Disease. 两害大于一害：严重低钠血症和横纹肌溶解是艾迪生病的表现特征。

Acta medica (Hradec Kralove) Pub Date : 2025-01-01 DOI: 10.14712/18059694.2025.16

Luca Foppiani, Christian Cascio, Paola Pesce, Giancarlo Antonucci

引用次数: 0

Beyond the Headlines: Why Henipaviruses Warrant Our Attention. 标题之外：为什么亨尼帕病毒值得我们关注

Acta medica (Hradec Kralove) Pub Date : 2025-01-01 DOI: 10.14712/18059694.2025.11

Biplab Adhikari

引用次数: 0

Intra-Operative and Post-Operative Impact of Body Weight on Total Hip Arthroplasty: Are We Approaching It Correctly? 术中及术后体重对全髋关节置换术的影响：我们是否正确处理？

Acta medica (Hradec Kralove) Pub Date : 2025-01-01 DOI: 10.14712/18059694.2025.15

Edoardo Ipponi, Sara Barderi, Elena Bechini, Belinda Misso, Luca Orsetti, Lorenzo Andreani, Nicola Piolanti, Enrico Bonicoli, Paolo Domenico Parchi

{"title":"Intra-Operative and Post-Operative Impact of Body Weight on Total Hip Arthroplasty: Are We Approaching It Correctly?","authors":"Edoardo Ipponi, Sara Barderi, Elena Bechini, Belinda Misso, Luca Orsetti, Lorenzo Andreani, Nicola Piolanti, Enrico Bonicoli, Paolo Domenico Parchi","doi":"10.14712/18059694.2025.15","DOIUrl":"https://doi.org/10.14712/18059694.2025.15","url":null,"abstract":"Background: To this date, the impact of body weight on total hip arthroplasty is still debated. The literature lacks evidence on the impact of body weight on surgical times and complications.Methods: We retrospectively evaluated all the patients who underwent primary total hip arthroplasty (THA), collecting patients' pre-operative BMI before surgery. We recorded the surgical approach performed (anterior or posterolateral), and their duration. All the major complications were recorded.Results: Seven-hundred-thirty-two cases were included (627 posterolateral and 105 anterior approach). The mean BMI was 27.3. The mean surgical time was 90.8 minutes (104.9 for anterior and 88.5 for posterolateral approach). We found a significant positive relationship between BMI and surgical times for both cases treated with a posterolateral approach, and (even more remarked) in case anterior approach. Thirty-nine cases (5.3%) had major complications; 27 of them (69.2%) were overweight or obese. The surgical times of those who had complications were significantly higher compared to others.Conclusions: Patients' body weight, and in particular their Body Mass index, has a direct impact on the duration of THA surgical procedures, particularly if performed using an anterior approach, and an indirect effect on complication rates.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 1","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Chondral Defect of the Knee Joint - Current Methods, Possibilities of Using Cultured Mesenchymal Stem Cells. 膝关节软骨缺损的治疗-现有方法，利用培养间充质干细胞的可能性。

Acta medica (Hradec Kralove) Pub Date : 2025-01-01 DOI: 10.14712/18059694.2025.12

Libor Prokeš, Tomáš Kučera

引用次数: 0

Clinical Evaluation of Oxidized Cellulose Powder and Endoscopic Applicator in Multicenter Trial. 氧化纤维素粉及内镜下涂抹器在多中心试验中的临床评价。

Acta medica (Hradec Kralove) Pub Date : 2025-01-01 DOI: 10.14712/18059694.2025.13

Petr Habal, Veronika Sívková, Zdeněk Šorm, Milan Chobola, Jiří Feix, Igor Slaninka, Jiřina Habalová, Tomáš Hosszú, Jaroslav Pacovský

{"title":"Clinical Evaluation of Oxidized Cellulose Powder and Endoscopic Applicator in Multicenter Trial.","authors":"Petr Habal, Veronika Sívková, Zdeněk Šorm, Milan Chobola, Jiří Feix, Igor Slaninka, Jiřina Habalová, Tomáš Hosszú, Jaroslav Pacovský","doi":"10.14712/18059694.2025.13","DOIUrl":"https://doi.org/10.14712/18059694.2025.13","url":null,"abstract":"Purpose: Oxidized cellulose-based haemostatic agents are widely used for managing bleeding in various surgical procedures. This study evaluates the efficacy and safety of oxidized cellulose powder and an endoscopic applicator across a broad spectrum of surgical settings.Methods: This was a prospective, multicentre study involving 99 evaluable patients undergoing surgeries with varying bleeding severities and surgical approaches (open, laparoscopic, or thoracoscopic). The primary endpoint was achieving haemostasis within 3 minutes and avoiding revision surgery within 12 hours. The time to haemostasis (TTH) and complications were recorded, and statistical comparisons were made using a paired and unpaired t-test, with a significance threshold of P < 0.05. Data from this study were compared to historical results from fibrillar haemostats.Results: Haemostasis was achieved within 3 minutes in 61.6% (95% CI [52.0, 71.2]) of patients and within 5 minutes in 99.0% (95% CI [97.0, 100.0]) of patients. The overall mean TTH was 153.8 seconds (95% CI: 141.5-166.1), with shorter TTH observed in minimally invasive procedures using the endoscopic applicator. Subgroup analysis revealed higher success rates for patients with mild bleeding (78%) compared to moderate bleeding (50%).Conclusion: Oxidized cellulose powder demonstrates reliable haemostatic performance across diverse surgical applications. The endoscopic applicator enhances precision and applicability, particularly in minimally invasive settings, making it a valuable tool in modern surgical practice.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between XRCC1 Arg399gln Polymorphism and Risk of Luminal Subtype Breast Cancer in Bali, Indonesia. 印尼巴厘岛地区XRCC1 Arg399gln多态性与Luminal亚型乳腺癌发病风险的关系

Acta medica (Hradec Kralove) Pub Date : 2025-01-01 DOI: 10.14712/18059694.2025.14

I Wayan Gede Sutadarma, I Gede Putu Supadmanaba, Putu Anda Tusta Adiputra, Anggi Amanda Triana Devy, Anak Agung Bagus Putra Indrakusuma, I Gede Aswin Parisya Sasmana

{"title":"Relationship Between XRCC1 Arg399gln Polymorphism and Risk of Luminal Subtype Breast Cancer in Bali, Indonesia.","authors":"I Wayan Gede Sutadarma, I Gede Putu Supadmanaba, Putu Anda Tusta Adiputra, Anggi Amanda Triana Devy, Anak Agung Bagus Putra Indrakusuma, I Gede Aswin Parisya Sasmana","doi":"10.14712/18059694.2025.14","DOIUrl":"https://doi.org/10.14712/18059694.2025.14","url":null,"abstract":"Background: Breast cancer is the second leading cause of cancer-related death and the most common type of cancer in women. Recent studies have shown that the development of carcinogenesis is influenced by impaired XRCC1 expression. Therefore, research on the relationship between the XRCC1 Arg399Gln polymorphism and the luminal subtype of breast cancer is important so that it can be used as a reference for further research development.Methods: This study lasted for 12 months at the Integrated Biomedical Laboratory and Biochemistry Laboratory, Faculty of Medicine, Udayana University. The samples consisted of 30 samples of stored biological material from previous studies with a case-control study design. The status of the XRCC1 Arg399Gln polymorphism was determined by performing PCR on blood samples. Furthermore, the samples were analyzed with SPSS version 25.0.Results: The number of samples in this study was 15 cases and 15 controls with the majority aged > 50 years. The results of the analysis showed that differences in age groups, menstrual status, and cancer grade were significantly associated with breast cancer subtypes (p < 0.05). Based on the results of sequencing and bivariate analysis, the XRCC1 Arg399Gln polymorphism acted as a protective risk factor for the development of luminal subtype breast cancer (OR = 0.182; p = 0.028).Conclusion: XRCC1 Arg399Gln polymorphism is associated with the risk of luminal subtype breast cancer in Bali.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 1","pages":"21-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal Jaundice: A Study of the Incidence in Children of Rh (D) Negative and 0 Rh (D) Positive Mothers. 新生儿黄疸：关于 Rh (D) 阴性和 0 Rh (D) 阳性母亲所生子女发病率的研究。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.19

Josef Urbanec, Kateřina Chládková, Magdalena Chvílová Weberová, Sylva Skálová, Jan Kremláček

引用次数: 0

Contrast-Induced Sialadenitis: An Under-Recognized Adverse Reaction in Radiology and Clinical Practice. 造影剂诱导的涎腺炎：放射学和临床实践中未被充分认识的不良反应。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2025.10

Alena Khalil, Kevin J Abrams, Charif Sidani, Márcio Luís Duarte, Leonardo Furtado Freitas

{"title":"Contrast-Induced Sialadenitis: An Under-Recognized Adverse Reaction in Radiology and Clinical Practice.","authors":"Alena Khalil, Kevin J Abrams, Charif Sidani, Márcio Luís Duarte, Leonardo Furtado Freitas","doi":"10.14712/18059694.2025.10","DOIUrl":"10.14712/18059694.2025.10","url":null,"abstract":"Contrast-induced sialadenitis (CIS), a rare inflammatory reaction of the salivary glands, occurs after exposure to iodinated contrast media (ICM). This self-limiting condition typically manifests as glandular swelling and pain, with variable severity, from hours to days post-contrast administration. Its etiology includes inflammatory edema, ductal obstruction, and pseudoallergic or idiosyncratic reactions. Non-ionic, low-osmolar agents such as Iohexol and Iodixanol are frequently implicated. Risk factors include iodine allergy, renal dysfunction, and inadequate premedication. Diagnostic imaging via CT or ultrasound reveals characteristic findings such as glandular enlargement, periglandular fat stranding, and heterogeneous enhancement, aiding differentiation from other causes like infection or neoplasms. This case series presents three patients who developed sialadenitis following contrast-enhanced CT scans. Presentations ranged from mild, localized submandibular swelling to rapid-onset bilateral glandular inflammation involving the parotid and submandibular glands. All cases highlight the need for prompt recognition and adherence to preventive measures, including premedication with corticosteroids and hydration, especially in high-risk patients. Management is largely supportive, involving corticosteroids, antihistamines, and NSAIDs, with severe cases requiring closer monitoring. By raising awareness of this underreported condition, this article underscores the importance of early recognition and differentiation from other conditions by radiologists, emphasizing their role in timely diagnosis and management. It also calls for further research to optimize prevention and management strategies.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 4","pages":"133-136"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Age on Predictive Capabilities of Ferritin, Ferritin-Hemoglobin Ratio, IL-6, and sIL-2R for COVID-19 Severity and Mortality. 年龄对铁蛋白、铁蛋白-血红蛋白比值、IL-6 和 sIL-2R 对 COVID-19 严重程度和死亡率的预测能力的影响。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.20

Oleksii Skakun, Yaroslava Vandzhura, Ihor Vandzhura, Khrystyna Symchych, Anton Symchych

{"title":"Impact of Age on Predictive Capabilities of Ferritin, Ferritin-Hemoglobin Ratio, IL-6, and sIL-2R for COVID-19 Severity and Mortality.","authors":"Oleksii Skakun, Yaroslava Vandzhura, Ihor Vandzhura, Khrystyna Symchych, Anton Symchych","doi":"10.14712/18059694.2024.20","DOIUrl":"https://doi.org/10.14712/18059694.2024.20","url":null,"abstract":"The study aimed to establish the impact of age on the predictive capability of ferritin, ferritin-hemoglobin ratio (FHR), IL-6, and sIL-2R in COVID-19 patients. Compared to patients with moderate condition, patients with severe condition had higher ferritin level (441.0 [188.0-829.8] ng/mL vs 281.0 [172.0-388.0] ng/mL, p = 0.002), sIL-2R level (6.0 [4.7-9.0] pg/mL vs 5.3 [3.7-6.9] pg/mL, p = 0.020), FHR (38.4 [15.1-63.4] vs 22.0 [12.1-32.1], p = 0.002). The area under the curves (AUC) for discriminative capabilities of the following biomarkers for severe condition were assessed in patients aged <65 years and patients aged ≥65 years: ferritin (AUC = 0.585, p = 0.309 vs AUC = 0.683, p = 0.002), FHR (AUC = 0.589, p = 0.302 vs AUC = 0.688, p = 0.002), IL-6 (AUC = 0.503, p = 0.972 vs AUC = 0.647, p = 0.019), and sIL-2R (AUC = 0.549, p = 0.552 vs AUC = 0.646, p = 0.017). Also AUCs for discriminative capabilities for in-hospital mortality were compared in patients aged <65 years and ≥65 years: ferritin (AUC = 0.607, p = 0.628 vs AUC = 0.661, p = 0.105), FHR (AUC = 0.612, p = 0.621 vs AUC = 0.688, p = 0.002), IL-6 (AUC = 0.580, p = 0.724 vs AUC = 0.695, p = 0.016), and sIL-2R (AUC = 0.620, p = 0.491 vs AUC = 0.695, p = 0.029). Thus, ferritin, FHR, IL-6, and sIL-2R didn't show acceptable predictive value for severe condition and lethal outcome in patients aged <65 years but had high predictive value for lethal outcome in patients aged ≥65 years.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 2","pages":"53-59"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed-Onset Muscle Soreness of the Psoas Major Muscle Following Abdominal Training: Case Report. 腹部训练后腰大肌延迟性肌肉酸痛：病例报告。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.23

Laura Gabriela Silva, Victor Sudário Takahashi, José Luiz Masson de Almeida Prado, Henrique Shimidu, Luís Henrique Paiva D'Elia, Márcio Luís Duarte

{"title":"Delayed-Onset Muscle Soreness of the Psoas Major Muscle Following Abdominal Training: Case Report.","authors":"Laura Gabriela Silva, Victor Sudário Takahashi, José Luiz Masson de Almeida Prado, Henrique Shimidu, Luís Henrique Paiva D'Elia, Márcio Luís Duarte","doi":"10.14712/18059694.2024.23","DOIUrl":"10.14712/18059694.2024.23","url":null,"abstract":"Edema of the psoas major muscle can indicate various pathologies, such as infection, malignancy, and trauma, but it can also result from benign causes like delayed-onset muscle soreness (DOMS). This article presents the case of a 44-year-old female patient who developed DOMS in the psoas major after participating in an intense abdominal workout. The patient reported hip pain that began a day after the workout, which was confirmed by magnetic resonance imaging (MRI) revealing significant edema in the psoas major muscles, particularly on the right side. Conservative treatment with rest and analgesics led to full recovery within two weeks. DOMS, typically associated with eccentric exercises, can be mistaken for more serious conditions, but its recognition is crucial to avoid unnecessary investigations and interventions. This case highlights the importance of clinical history and imaging findings in distinguishing DOMS from other causes of muscle edema, emphasizing the need for accurate diagnosis to ensure appropriate management.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 2","pages":"69-71"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0