Acta medica (Hradec Kralove)最新文献_第2页

The Role of Digital Facebow for CAD/CAM Implant-Supported Crowns Workflow. 数字化 Facebow 在 CAD/CAM 种植体支持冠工作流程中的作用。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.16

Lenka Vavřičková, Martin Kapitán, Jan Schmidt

{"title":"The Role of Digital Facebow for CAD/CAM Implant-Supported Crowns Workflow.","authors":"Lenka Vavřičková, Martin Kapitán, Jan Schmidt","doi":"10.14712/18059694.2024.16","DOIUrl":"10.14712/18059694.2024.16","url":null,"abstract":"Recent advancements in digital technologies have transformed clinical workflows in dentistry, ensuring precise restorations. Custom-made crowns and fixed partial dentures (FPDs) now rely on virtual articulation. The digital facebow provides individualized data for CAD settings, streamlining the fabrication via digital workflow. For the purpose of demonstrating the differences observed during fabrication, we present a case report involving a 68-year-old patient seeking a replacement for missing teeth 24, 25, 26, and 27. The treatment plan involved the fabrication of an implant-supported FPD using monolithic zirconia (ZrO2). However, technical hurdles emerged during the planning phase, primarily due to spatial limitations posing a risk of mechanical failure over time. Consequently, we pivoted approach towards a porcelain fused to metal (PFM) FPD. For the PFM FPD, individual values from the digital facebow adjusted both virtual and conventional articulators. For comparison, two ZrO2 FPDs were milled-individual settings and average settings. All restorations underwent assessment for occlusion in maximal intercuspal position and eccentric mandible movements. In conclusion, the case report showed that individualized PFM FPD required minimal adjustments compared to milled ZrO2 restorations, whether using individual or average values. Utilizing individual values from the digital facebow reduced operator working time and minimized the intraoral adjustments.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 1","pages":"26-31"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

VIPoma: An Unusual Cause of Chronic Diarrhea. VIPoma：慢性腹泻的不寻常原因

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.22

Sutharin Suteetorn, Krit Kitisin, Natcha Wanpiyarat, Supaksorn Kunjan, Thiti Snabboon

{"title":"VIPoma: An Unusual Cause of Chronic Diarrhea.","authors":"Sutharin Suteetorn, Krit Kitisin, Natcha Wanpiyarat, Supaksorn Kunjan, Thiti Snabboon","doi":"10.14712/18059694.2024.22","DOIUrl":"10.14712/18059694.2024.22","url":null,"abstract":"Chronic diarrhea is a significant challenge in clinical practice because of its high prevalence and various causes. Comprehensive clinical assessment and stepwise laboratory approach are crucial for an accurate diagnosis. This report presents a case of an adult woman who experienced chronic watery diarrhea, complicated by renal impairment and multiple electrolyte imbalances, including hypokalemia, hypophosphatemia, and metabolic acidosis. The diagnosis of a vasoactive intestinal polypeptide-secreting tumor (VIPoma) with liver metastases was confirmed by elevated serum levels of a vasoactive intestinal polypeptide (VIP) and imaging findings of a pancreatic mass with multiple hepatic lesions. Preoperative management, including fluid rehydration, electrolyte correction, and somatostatin analog therapy, significantly improved her clinical symptoms. Subsequent surgical tumor removal and radiofrequency ablation of the hepatic lesions resulted in complete resolution of symptoms and normalized VIP levels. This case emphasizes the importance of early recognition of this rare tumor in patients with chronic diarrhea to improve clinical outcomes.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 2","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

P(A)SH Syndrome: Case Presentation and Short Update of Related Disorders. P(A)SH综合征：病例介绍和相关疾病的简短更新。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2025.9

Simona Kordeva, Alice Hristova, Valentina Broshtilova, Georgi Tchernev

{"title":"P(A)SH Syndrome: Case Presentation and Short Update of Related Disorders.","authors":"Simona Kordeva, Alice Hristova, Valentina Broshtilova, Georgi Tchernev","doi":"10.14712/18059694.2025.9","DOIUrl":"10.14712/18059694.2025.9","url":null,"abstract":"Hidradenitis suppurativa (HS) is a chronic inflammatory disease that is frequently associated with syndromes, such as those within the PAPA spectrum. Syndromic HS presents unique management challenges, as it often shows resistance to conventional therapies. Pyoderma gangrenosum is a rare inflammatory neutrophilic dermatosis that is often seen in association within the spectrum of autoinflammatory diseases. The PAPA spectrum disorders include a group of autoinflammatory diseases characterized by mutations in the PSTPIP1 gene or by clinical manifestations that closely resemble or overlap with those of PAPA syndrome. Each syndrome (PASH, PAPASH, PsAPASH, PASS, PAC, and PAMI syndrome) in this spectrum highlights specific inflammatory pathways and symptoms, providing insight into targeted therapeutic approaches. Here, we present a rare case of incomplete PASH (pyoderma gangrenosum and hidradenitis suppurativa) syndrome successfully managed with a standard combination of antibiotics (ceftriaxone and metronidazole) and corticosteroids (methylprednisolone), followed by immunosuppressant (azathioprine) and corticosteroids (dexamethasone). We review both novel and established/standard treatment options, with an emphasis on treatment outcomes. Conventional therapies remain both effective and affordable, providing valuable alternatives for patients.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 4","pages":"125-132"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging Findings of Solitary Fibrous Tumors of the Gallbladder. 胆囊孤立性纤维性肿瘤的影像学表现。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2025.5

Trinh Anh Tuan, Le-Thi Mai Huong, Nguyen Thu Minh Chau, Ngo Quang Duy, Nguyen-Thi Hai Anh, Nguyen Duy Hung, Luc Ceugnart, Nguyen Minh Duc

引用次数: 0

Academic Responsibilities, Obligations, and Freedom: A Call for Review - In Memory of Professor Dr. Tomáš Hudlický. 学术责任、义务和自由：呼吁回顾--纪念 Tomáš Hudlický 教授博士。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.17

Consolato M Sergi

引用次数: 0

Visual Acuity Screening of Refugees and Immigrants with a Web-Based Digital Test: A Pilot Study. 基于网络的数字测试对难民和移民的视力筛查：一项试点研究。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2025.2

Minas Bakirtzis, Eirini Michaleakou, Maria-Eleni Martidou, Eleni Lahana, Petros Kostagiolas, Dimitris Niakas, Georgios Labiris

{"title":"Visual Acuity Screening of Refugees and Immigrants with a Web-Based Digital Test: A Pilot Study.","authors":"Minas Bakirtzis, Eirini Michaleakou, Maria-Eleni Martidou, Eleni Lahana, Petros Kostagiolas, Dimitris Niakas, Georgios Labiris","doi":"10.14712/18059694.2025.2","DOIUrl":"10.14712/18059694.2025.2","url":null,"abstract":"Purpose: To screen visual acuity in two refugee camps in Greece and explore the feasibility of replicating these methods on a nationwide scale.Methods: Visual acuity was assessed in all participants using web-based Democritus Digital Acuity & Reading Test (DDART). Furthermore, the immigrants responded to a structured questionnaire regarding their demographics and medical history.Results: A total of 330 adult refugees and immigrants were recruited. A total of 47.3% of the patients had never undergone ophthalmological examination. A significant negative correlation was detected between age (r = -0.207, p < 0.001) and educational background (r = -0.135, p = 0.014), suggesting that younger immigrants who had attended compulsory education were more likely to have their eyes checked in their home country. A total of 6.97% of patients presented with impaired vision and were referred for further care. All remote DDART measurements presented no differences from the corresponding hospital-based data in the referred cases.Conclusions: Visual acuity screening using DDART provides valuable information regarding the visual capacity of refugees. The study outcomes suggest that pilot methods can be replicated on a nationwide scale.Clinical trials: Gov number NCT05209581; date of registration: January 13, 2022. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors have no funding or conflicts of interest to disclose. Patients Consent Statement: The patients sign written consent form.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 3","pages":"79-86"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical Manifestation of X-linked Agammaglobulinemia - the Importance of Genetic Testing. X 连锁阿加球蛋白血症的非典型表现--基因检测的重要性。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.21

Adam Markocsy, Daniela Kapustová, Andrej Čereš, Eva Froňkova, Miloš Jeseňák

{"title":"Atypical Manifestation of X-linked Agammaglobulinemia - the Importance of Genetic Testing.","authors":"Adam Markocsy, Daniela Kapustová, Andrej Čereš, Eva Froňkova, Miloš Jeseňák","doi":"10.14712/18059694.2024.21","DOIUrl":"10.14712/18059694.2024.21","url":null,"abstract":"X-linked agammaglobulinemia (XLA) was one of the first inborn errors of immunity to be described. It is caused by pathogenic variants in the gene for Bruton tyrosine kinase (BTK), which has important functions in B cell development and maturation. Recurrent bacterial infections in the first two years of life and hypogammaglobulinemia with absent B cells in male patients are the most common symptoms. A four-month-old male patient underwent surgical removal of urachus persistens complicated with recurrent scar abscesses. Hypogammaglobulinemia (IgG, IgA, and IgM), low phagocytic activity, mild neutropenia, and a normal percentage of B cells were observed in the patient's immune laboratory profile. Over time, he suffered recurrent respiratory infections (otitis media and rhinosinusitis) and developed B cell depletion, but interestingly, this was with a normalisation of IgG and IgA levels along with undetectable IgM. Molecular-genetic testing confirmed the presence of the pathogenic variant c.1843C>T in the BTK gene, which is associated with a milder phenotype of XLA. Molecular-genetic testing uncovers the variability of clinical and laboratory features of apparently well-known inherited disorders. Patients with mild \"leaky\" XLA may have normal levels of non-functional or oligoclonal immunoglobulins.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 2","pages":"60-63"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zirconia Ceramics. 氧化锆陶瓷。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2024.18

Bedirhan Savas Yigit, Marwan Al-Akkad, Radek Mounajjed

引用次数: 0

Sensorineural Hearing Loss in Otosclerosis Surgery. 耳硬化症手术中的感音神经性听力损失。

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2025.1

Kristýna Néma, Viktor Chrobok, Jan Mejzlík, Vladimír Pavlík, Lukáš Školoudík

{"title":"Sensorineural Hearing Loss in Otosclerosis Surgery.","authors":"Kristýna Néma, Viktor Chrobok, Jan Mejzlík, Vladimír Pavlík, Lukáš Školoudík","doi":"10.14712/18059694.2025.1","DOIUrl":"https://doi.org/10.14712/18059694.2025.1","url":null,"abstract":"Background: During otosclerosis surgery, operative trauma can lead to decreased bone conduction.Aims: The study aims to observe the bone conduction changes after otosclerosis operations and analyse possible factors affecting the postoperative decrease in bone conduction.Material and methods: Authors retrospectively processed the data of 109 patients and evaluated pure tone audiometry before surgery and consequently 2 days, 1 month and 1 year after surgery.Results: We noted a deterioration of bone conduction >5 dB on the second postoperative day in 28% (30/109) of patients, which persisted one year after the surgery in 9% (10/109) cases. Analysis of individual factors affecting bone conduction loss revealed a higher risk of permanent loss of bone conduction in patients with early postoperative loss in higher frequencies, in older patients and patients with a preoperative threshold of bone conduction >20 dB. Revision surgery was not a statistically significant factor.Conclusion and significance: The bone conduction decrease after otosclerosis surgery is usually temporary. The recovery of bone conduction is influenced by the age of patients and the level of bone conduction before the surgery. The early postoperative decrease of bone conduction in higher frequencies is a negative predictive factor for permanent hearing loss.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"67 3","pages":"73-78"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colloid Cyst of the Third Ventricle: A Case Report. 第三脑室胶体囊肿：病例报告

Acta medica (Hradec Kralove) Pub Date : 2024-01-01 DOI: 10.14712/18059694.2025.4

Aleš Kopal, Jiří Preis, Leoš Ungermann, Edvard Ehler, Ivana Štětkářová

引用次数: 0