Acta medica (Hradec Kralove)最新文献

{"title":"Peritendinitis of the Fourth Dorsal Compartment Due to Anomalous Extensor Indicis Proprius: A Case Report and Review of Anatomical Variations.","authors":"Dimas Drummond, José Luiz Masson de Almeida Prado, Henrique Shimidu, Márcio Luís Duarte","doi":"10.14712/18059694.2025.23","DOIUrl":"10.14712/18059694.2025.23","url":null,"abstract":"<p><p>Anomalous extensor indicis proprius (EIP) tendons are rare anatomical variations that can cause wrist pain and dysfunction due to tendon compression and inflammation. These variations, though often asymptomatic, are implicated in conditions such as fourth extensor compartment peritendinitis, requiring accurate diagnosis and tailored treatment. We report the case of a 56-year-old man with chronic right wrist pain lasting eight months, primarily aggravated by finger extension. Physical examination revealed a tender nodule on the dorsum of the wrist and pain elicited by the Spinner test, indicating involvement of the fourth dorsal compartment. Magnetic resonance imaging (MRI) showed an anomalous, thickened EIP tendon with peritendinitis. The patient opted for conservative management, including nonsteroidal anti-inflammatory drugs (NSAIDs) and activity modification, which led to complete symptom resolution within two weeks. This case highlights the clinical relevance of EIP tendon anomalies, which can mimic other wrist pathologies. The Spinner test and imaging modalities such as MRI are essential for diagnosis. While conservative treatment is often sufficient, surgical decompression may be necessary in refractory cases. Awareness of these rare anatomical variations is crucial for accurate diagnosis and effective management, ensuring better outcomes for patients with wrist pain.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 2","pages":"73-75"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145254296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EUS Guided FNA Cell Block Cytology and Intraoperative Squash Cytology in the Diagnostic Approach of Unfamiliar Malignant Neoplastic Disorders.","authors":"Alexandra Kalogeraki, Dimitrios Tamiolakis, Eleni Moustou, Evangelos Kalaitzakis","doi":"10.14712/18059694.2025.22","DOIUrl":"10.14712/18059694.2025.22","url":null,"abstract":"<p><p>Endoscopic ultrasound guided fine needle aspiration cytology (EUS-FNAC) with the employment of cell block preparations and intraoperative squash smear cytology upgrade the interpretation accuracy and typing of common malignant lesions. Yet, their capacity in the diagnostic workup of less familiar neoplastic entities is not clearly determined and this analysis was designed towards this direction. We describe four cases of patients with uncommon malignancies and evaluate EUS-FNA cell block cytology and intraoperative squash smear cytology as a necessary (important) step in rendering the diagnosis. All cases enhance the diagnostic role of cytology in a wide variety of neoplastic disorders including lymphoproliferative conditions and rare carcinomas.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 2","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145254309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Evaluation of Oxidized Cellulose Powder and Endoscopic Applicator in Multicenter Trial.","authors":"Petr Habal, Veronika Sívková, Zdeněk Šorm, Milan Chobola, Jiří Feix, Igor Slaninka, Jiřina Habalová, Tomáš Hosszú, Jaroslav Pacovský","doi":"10.14712/18059694.2025.13","DOIUrl":"10.14712/18059694.2025.13","url":null,"abstract":"<p><strong>Purpose: </strong>Oxidized cellulose-based haemostatic agents are widely used for managing bleeding in various surgical procedures. This study evaluates the efficacy and safety of oxidized cellulose powder and an endoscopic applicator across a broad spectrum of surgical settings.</p><p><strong>Methods: </strong>This was a prospective, multicentre study involving 99 evaluable patients undergoing surgeries with varying bleeding severities and surgical approaches (open, laparoscopic, or thoracoscopic). The primary endpoint was achieving haemostasis within 3 minutes and avoiding revision surgery within 12 hours. The time to haemostasis (TTH) and complications were recorded, and statistical comparisons were made using a paired and unpaired t-test, with a significance threshold of P < 0.05. Data from this study were compared to historical results from fibrillar haemostats.</p><p><strong>Results: </strong>Haemostasis was achieved within 3 minutes in 61.6% (95% CI [52.0, 71.2]) of patients and within 5 minutes in 99.0% (95% CI [97.0, 100.0]) of patients. The overall mean TTH was 153.8 seconds (95% CI: 141.5-166.1), with shorter TTH observed in minimally invasive procedures using the endoscopic applicator. Subgroup analysis revealed higher success rates for patients with mild bleeding (78%) compared to moderate bleeding (50%).</p><p><strong>Conclusion: </strong>Oxidized cellulose powder demonstrates reliable haemostatic performance across diverse surgical applications. The endoscopic applicator enhances precision and applicability, particularly in minimally invasive settings, making it a valuable tool in modern surgical practice.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Immaturity CD Markers Expression between Pediatric and Adult Acute Lymphoblastic Leukemia: Insights and Implications for Diagnostic and Therapeutic Strategies.","authors":"Ihsan Mardan Al-Badran, Ahmed Mardan Al-Badran","doi":"10.14712/18059694.2025.19","DOIUrl":"https://doi.org/10.14712/18059694.2025.19","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study is to assess the expression levels of different immaturity CD markers in diverse subtypes of Acute Lymphoblastic Leukemia (ALL) among children and adults, and determine any statistically significant variations in marker expression between these two groups.</p><p><strong>Methods: </strong>This dataset included CD marker expressions (CD34, HLA-DR, TdT, and CD38) for 130 ALL patients (51 pediatric B-ALL, 16 pediatric T-ALL, 44 adult B-ALL, and 19 adult T-ALL patients). The Shapiro-Wilk test analysis was conducted to check for normality distribution in all data points before proceeding with the statistical analysis test. As a result for each marker within these subtypes, descriptive statistics were calculated. Independent samples t-tests were initially conducted to compare mean expression levels of CD markers between groups. Moreover, since non-normal distributions are likely to occur, Mann-Whitney U tests were used for Pediatric T-ALL and Adult T-ALL.</p><p><strong>Results: </strong>Descriptive analysis indicated variability in CD marker expression levels among the different subtypes of ALL. Both t-tests and Mann-Whitney U tests revealed statistically significant differences (p < 0.05) in the expression levels of CD markers between pediatric and adult groups, or between B-ALL and T-ALL groups.</p><p><strong>Conclusion: </strong>Significant differences have been identified using different analysis methods across the studied groups. The investigation analyzes the expression levels of CD34, HLA-DR CD38, and TdT within pediatric B-ALL patients and pediatric T-ALL patients along with adult B-ALL patients and adult T-ALL patients. The patterns need appreciation because they might reveal biological differences at their base which influence disease development and both treatment results and patient survival outcomes.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 2","pages":"50-57"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145254327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Copeptin (Not Only) in Water and Sodium Disorders.","authors":"Jan Drugda, Filip Gabalec, Jiří Horáček","doi":"10.14712/18059694.2025.24","DOIUrl":"10.14712/18059694.2025.24","url":null,"abstract":"<p><p>Arginine vasopressin (AVP) is a key regulator of fluid balance and vascular tone. Its diagnostic utility in various disorders is limited by its short half-life, pulsatile secretion, and preanalytical instability. Copeptin, the C-terminal fragment of preprovasopressin, is secreted in equimolar amounts with AVP and offers a stable, easily measurable surrogate marker. This review highlights the clinical relevance of copeptin in the differential diagnosis of polyuria-polydipsia syndrome, hyponatraemia, critical illness, cardiovascular disease and diabetes mellitus. Copeptin improves diagnostic accuracy, particularly in differentiating types of diabetes insipidus and in the early exclusion of acute myocardial infarction. It also shows prognostic value in heart failure, stroke, and diabetic complications. Given its broad diagnostic potential and analytical advantages, copeptin represents a valuable biomarker for AVP-related pathologies.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 3","pages":"77-81"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Ordinary: Giant Parotid Oncocytoma and the Complexity of Diagnosis.","authors":"Burak Kaan İnan, Altan Argun, Saim Pamuk, Mehmet Akif Abakay, İbrahim Sayın, Zahide Mine Yazıcı","doi":"10.14712/18059694.2025.21","DOIUrl":"https://doi.org/10.14712/18059694.2025.21","url":null,"abstract":"<p><p>Parotid oncocytoma is a rare benign salivary gland tumor, often misdiagnosed due to overlapping features with other parotid neoplasms. We present the case of an 87-year-old male with a progressively enlarging right parotid mass, confirmed as oncocytoma through imaging and histopathological analysis. The excised oncocytoma measured approximately 9 cm in its greatest dimension, making it one of the largest parotid oncocytomas reported in the literature to date. This case highlights the diagnostic challenges associated with parotid oncocytomas, the limitations of fine-needle aspiration, and the importance of comprehensive diagnostic tools. Surgical resection was curative, with no recurrence at 12 months.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 2","pages":"63-66"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145254355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Urine Kidney Injury Molecule-1 as an Early Biomarker for Nephropathy in Sickle Cell Anaemia Patients.","authors":"Akeem Olayinka Busari, Shola Lois Jolayemi, Muhammad Bello Ahmad, Renata Trentin Perdomo","doi":"10.14712/18059694.2025.27","DOIUrl":"10.14712/18059694.2025.27","url":null,"abstract":"<p><strong>Background: </strong>Sickle cell anemia (SCA), a form of sickle cell disorder (SCD), is characterized by chronic hemolytic anemia, recurrent acute and persistent pain episodes, and progressive multiorgan complications. Among these, sickle cell nephropathy (SCN) is a significant and severe complication that may advance to chronic kidney disease (CKD), often beginning asymptomatically in childhood. Despite its clinical relevance, data on the early assessment of renal function in patients with SCA remain limited in Nigeria, hindering timely detection and intervention. This study, therefore, investigates the diagnostic utility of urinary kidney injury molecule-1 (KIM-1) as a biomarker for renal dysfunction in patients with steady-state SCA.</p><p><strong>Objective: </strong>This study assessed urinary kidney injury molecule 1 as an early biomarker of nephropathy in patients with sickle cell anemia.</p><p><strong>Method: </strong>This cross-sectional comparative study included ninety participants, comprising forty-five individuals with a normal hemoglobin genotype (HbAA) and forty-five with sickle cell anemia (HbSS). Hemoglobin genotype was determined using cellulose acetate electrophoresis. Serum creatinine levels were measured using the modified Jaffe method, and the estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Urinary kidney injury molecule-1 (KIM-1) concentrations were assessed using the enzyme-linked immunosorbent assay (ELISA) technique.</p><p><strong>Results: </strong>This study observed no significant difference in mean age between the HbAA and HbSS groups (14.16 ± 2.54 vs. 13.52 ± 3.33 years; p = 0.121). However, the mean body mass index (BMI) was significantly higher in the HbAA group (21.40 ± 1.02 kg/m2) compared to the HbSS group (18.69 ± 2.19 kg/m2; p = 0.004). Serum creatinine levels did not differ significantly between the two groups (p = 0.311). In contrast, urinary KIM-1 levels were significantly elevated in the HbSS group relative to the HbAA group (p r = -0.64, p = 0.005; HbSS: r = -0.79, p = 0.002).</p><p><strong>Conclusion: </strong>The findings from this study observed no significant difference in serum creatinine levels between individuals with HbAA and HbSS genotypes. However, urinary KIM-1 concentrations were significantly higher in the HbSS group, with a stronger negative correlation with eGFR. These findings suggest that, while serum creatinine may not be effective in detecting early renal impairment in sickle cell anemia, urinary KIM-1 has promising potential for detecting renal dysfunction in this population.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 3","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between XRCC1 Arg399gln Polymorphism and Risk of Luminal Subtype Breast Cancer in Bali, Indonesia.","authors":"I Wayan Gede Sutadarma, I Gede Putu Supadmanaba, Putu Anda Tusta Adiputra, Anggi Amanda Triana Devy, Anak Agung Bagus Putra Indrakusuma, I Gede Aswin Parisya Sasmana","doi":"10.14712/18059694.2025.14","DOIUrl":"https://doi.org/10.14712/18059694.2025.14","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer is the second leading cause of cancer-related death and the most common type of cancer in women. Recent studies have shown that the development of carcinogenesis is influenced by impaired XRCC1 expression. Therefore, research on the relationship between the XRCC1 Arg399Gln polymorphism and the luminal subtype of breast cancer is important so that it can be used as a reference for further research development.</p><p><strong>Methods: </strong>This study lasted for 12 months at the Integrated Biomedical Laboratory and Biochemistry Laboratory, Faculty of Medicine, Udayana University. The samples consisted of 30 samples of stored biological material from previous studies with a case-control study design. The status of the XRCC1 Arg399Gln polymorphism was determined by performing PCR on blood samples. Furthermore, the samples were analyzed with SPSS version 25.0.</p><p><strong>Results: </strong>The number of samples in this study was 15 cases and 15 controls with the majority aged > 50 years. The results of the analysis showed that differences in age groups, menstrual status, and cancer grade were significantly associated with breast cancer subtypes (p < 0.05). Based on the results of sequencing and bivariate analysis, the XRCC1 Arg399Gln polymorphism acted as a protective risk factor for the development of luminal subtype breast cancer (OR = 0.182; p = 0.028).</p><p><strong>Conclusion: </strong>XRCC1 Arg399Gln polymorphism is associated with the risk of luminal subtype breast cancer in Bali.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 1","pages":"21-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes and Survival of Peritoneal Dialysis Beyond 10 Years: A Single-Center Study.","authors":"Hmaidouch Nabil, El Kadiri Nada, Ouzeddoun Naima, Benamar Loubna","doi":"10.14712/18059694.2025.28","DOIUrl":"10.14712/18059694.2025.28","url":null,"abstract":"<p><strong>Introduction: </strong>Long-term peritoneal dialysis (PD) beyond 10 years is uncommon and reflects both advances in dialysis care and the complexity of long-term patient management. The objective of this study is to describe the clinical characteristics, complications, and outcomes of patients undergoing peritoneal dialysis for more than 10 years, and to identify factors associated with long-term technique survival.</p><p><strong>Methods: </strong>This is a retrospective, descriptive, and analytical study including 12 patients treated with peritoneal dialysis (PD) for more than 10 years between June 2006 and January 2024. Data collected included demographics, comorbidities, dialysis parameters, complications, and outcomes.</p><p><strong>Results: </strong>The mean age at PD initiation was 45.5 ± 16.5 years. Tubulointerstitial nephropathy was the most common etiology of end-stage kidney disease. The mean duration on PD was 10.4 ± 0.9 years. During follow-up, residual kidney function significantly declined. Seven patients remained on PD at last follow-up. The peritonitis rate was low (0.024 episodes/patient-month), with favorable technique survival and no cases of encapsulating peritoneal sclerosis.</p><p><strong>Discussion: </strong>PD beyond 10 years is feasible with proper patient selection, education, and follow-up. Preservation of residual kidney function and effective management of complications are key to long-term success, especially in non-transplantable patients.</p>","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 3","pages":"101-106"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral Microcirculation Alterations as an Indicator of Predisposition to Tendon Degeneration of the Shoulder Joint: A Preliminary Study.","authors":"Lorenzo Svolacchia, Fabiano Svolacchia","doi":"10.14712/18059694.2025.29","DOIUrl":"10.14712/18059694.2025.29","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The etiology of rotator cuff tear (RCT) is multifactorial and includes extrinsic and intrinsic factors. Alterations of the peripheral microcirculation represent a main intrinsic etiological factor; recent evidence demonstrates that at the level of the rotator cuff tendons there is significant reduction in capillary density and microvascular blood flow. On the basis of the alterations of the microcirculation present at the level of the rotator cuff (RC) tendons, the aim of our study was to evaluate the possible presence of alterations of the peripheral nail microcirculation, through capillaroscopic examination, in a consecutive series of patients with RCT, comparing them with an adequate control group. The hypothesis of our study is that the alteration of the local microcirculation is accompanied in patients with RCT by an alteration of the peripheral microcirculation that may represent a systemic predisposing factor for tendon degeneration.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;A case-control study was conducted. The Case Group consisted of 82 patients (mean age 61 years ± 8) with RCT, the size of which was assessed intraoperatively and classified into small, large and massive according to Snyder; the control group was represented by 43 healthy subjects (mean age 63 years ± 9). All control subjects underwent ultrasound examination to objectively exclude rotator cuff tears. All participants underwent a nail capillaroscopic examination of the hands to evaluate morphological and dynamic parameters. The data was subsequently analyzed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In the Case Group, 34 patients had a small RC lesion, 23 had a large lesion, and 25 had a massive lesion. The main capillaroscopic differences between cases and controls were found in the morphology of the capillary loops and in the flow. In the group of cases, 50% have normal loops, 47.56% have tortuous loops and 2.44% have branched loops; in the control group 62.79% had normal loops, 34.88% had tortuous loops and 2.33% had branched loops. The capillary flow was normal in 46.34% of the cases group, granular in 48.78% and slowed in 2.44%. 95.35% of the control group had normal flow and 2.33% grainy flow. Regarding the severity of the lesion, no significant differences were found between patients with small, large and massive lesion (small lesion: 50% normal loops, 41.2% normal flow; large lesion: 52% normal loops, 47.8% normal flow; massive lesion: 48% normal loops, 48% normal flow).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The prevalence of capillaroscopic alterations was higher in patients with rotator cuff tears: the capillary loops are more tortuous and present ectasias more frequently than in the control group. Additionally, capillary flow in patients with RCT is grainier and slowed. However, the compromise of the capillary picture is not proportional to the severity of the tendon lesion, limiting the direct clinical applicability of this finding.","PeriodicalId":101400,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"68 3","pages":"107-112"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}