Sahil Patel , Emily Kao , Xu Wang , Kristyn Ringgold , Jeff Thiel , Nathan White , Shahram Aarabi , Daniel F. Leotta
{"title":"A novel 4D volumetric M-mode ultrasound scanning technique for evaluation of intravascular volume and hemodynamic parameters","authors":"Sahil Patel , Emily Kao , Xu Wang , Kristyn Ringgold , Jeff Thiel , Nathan White , Shahram Aarabi , Daniel F. Leotta","doi":"10.1016/j.wfumbo.2024.100058","DOIUrl":"10.1016/j.wfumbo.2024.100058","url":null,"abstract":"<div><h3>Introduction</h3><p>We use a novel 4-dimensional (4D) volumetric M-mode (VMM) ultrasound (US) technique to assess intravascular volume by monitoring the inferior vena cava (IVC). The VMM method expands the spatial coverage of standard M-mode scanning (depth vs time) by including lateral image direction and adds transducer tilt to cover the region surrounding the IVC. Current ultrasound methods for volume assessment suffer from intra- and inter-operator variability. The VMM technique aims to address these limitations, aiding in early detection of hypovolemia/hemorrhage and guiding resuscitation.</p></div><div><h3>Methods/technical approach</h3><p>The 4D VMM technique was used on animals that underwent a swine hemorrhagic shock protocol with fluid resuscitation. 2D ultrasound images obtained were formatted in a 3D volume to capture changes over time in vessel size with respiration and volume status. Planes were then extracted from the 3D volume at multiple lateral locations to find and track the IVC. The vessel walls were manually traced on vertical planes (depth vs. time) to determine mean IVC diameter and IVC collapsibility at each measurement time point in the shock/resuscitation protocol. Planes at constant depth (lateral vs. time) were selected to extract respiratory and cardiac cycle data.</p></div><div><h3>Results</h3><p>Mean IVC diameter in the baseline phase was significantly greater than in the hemorrhage phase (p = 0.020). There was no significant different in mean IVC diameter between baseline and resuscitation (p = 0.064) or hemorrhage and resuscitation phases (p = 0.531). There was no statistically significant difference in mean collapsibility or ΔIVC diameter between protocol phases. The 4D VMM technique effectively measured heart and respiratory rates, consistent with monitored vitals.</p></div><div><h3>Conclusion</h3><p>4D VMM identified IVC changes corresponding to blood loss and resuscitation during hemorrhagic shock as well as heart/respiratory rates. This innovative approach holds promise in reducing operator variability and providing actionable information during treatment of shock.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000260/pdfft?md5=6bc463d87f8bd57e910db0b8ee1bbe04&pid=1-s2.0-S2949668324000260-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Cao , Alex Jayyosi , Jennifer Nietupski , Giulio Tomassy , Ingeborg M. Langohr , Michelle Potter , Srinivas Rao , Dinesh S. Bangari , Xiaoyou Ying
{"title":"Ultrasound imaging for assessing aortic phenotypes: A preclinical tool for measuring cardiac disease model progression and therapeutic effect","authors":"James Cao , Alex Jayyosi , Jennifer Nietupski , Giulio Tomassy , Ingeborg M. Langohr , Michelle Potter , Srinivas Rao , Dinesh S. Bangari , Xiaoyou Ying","doi":"10.1016/j.wfumbo.2024.100060","DOIUrl":"10.1016/j.wfumbo.2024.100060","url":null,"abstract":"<div><p>Cardiac dysfunction is a common feature of numerous diseases, ranging from metabolic disorders like Mucopolysaccharidosis Type 1 (MPS I), a.k.a. Hurler syndrome to neuromuscular disorders such as Myotonic Dystrophy type 1 (DM1). The ability to quantify cardiac abnormalities in animal models of these diseases is a valuable translational tool for preclinical testing of novel therapeutic approaches. In contrast to methods that measure the left ventricle (LV) phenotype, we employed ultrasound imaging to assess the ascending aortic diameter and ascending aortic blood velocity.</p></div><div><h3>Methods</h3><p>We imaged two disease models - MPS I Hurler mouse model and DM1 mouse model (DMSXL) - using the Vevo2100 platform. Ascending aortic diameter in the proximal thoracic aortic region and ascending aortic blood velocity just before the branching point of the brachiocephalic artery were measured as rapid imaging readouts. In addition, histopathology was performed on relevant tissue samples.</p></div><div><h3>Results</h3><p>The two mouse models demonstrate opposing aorta phenotypes. Hurler mice had a dilated aorta and slightly increased blood velocity with disease progression, while the aorta diameter in DMSXL mice narrowed and had a blood velocity decrease as the disease progressed. In the Hurler model, we demonstrated that a single dose of adeno-associated virus (AAV) delivered gene therapy provides aortic phenotype improvement. In the DMSXL model, we established aortic phenotype criteria at baseline.</p></div><div><h3>Conclusion</h3><p>Ultrasound imaging of aortic diameter and blood velocity can offer objective and longitudinal assessments of disease progression and treatment efficacy in real time. This method might therefore have noninvasive clinical applicability as phenotype indicator of cardiac dysfunction.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100060"},"PeriodicalIF":0.0,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000284/pdfft?md5=1a56e979162a16019bd4a64cd6c8458f&pid=1-s2.0-S2949668324000284-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shown Haluzani , Agripa Lungu , Mweetwa Mudenda , Arnold Hamapa , Catherine Mkandawire , Abraham Kaluba , Oswell Khondowe , Mushelelwa Mutale , Karren Imasiku , Muyereka Nyirenda , Osbert Nkolola , Lackson Kasonka , Felix Simute , Angel Mwiche , Evarist Njelesani , Peter Mwaba , C. Viner Alexandra , David Lissauer , Mubambe Mulaya , Desire Kabamba , Lydia Hangulu
{"title":"Quality of ultrasound images by midwives implementing ultrasound scanning services during antenatal clinics within selected healthcare facilities of Zambia","authors":"Shown Haluzani , Agripa Lungu , Mweetwa Mudenda , Arnold Hamapa , Catherine Mkandawire , Abraham Kaluba , Oswell Khondowe , Mushelelwa Mutale , Karren Imasiku , Muyereka Nyirenda , Osbert Nkolola , Lackson Kasonka , Felix Simute , Angel Mwiche , Evarist Njelesani , Peter Mwaba , C. Viner Alexandra , David Lissauer , Mubambe Mulaya , Desire Kabamba , Lydia Hangulu","doi":"10.1016/j.wfumbo.2024.100057","DOIUrl":"10.1016/j.wfumbo.2024.100057","url":null,"abstract":"<div><h3>Background</h3><p>Limited access to ultrasound services in low and middle-income countries (LMICs) prompts the development of an intensive training program for midwives. The aim of this study was to evaluate the quality of ultrasound images produced by midwives and assess their competency in gestational age assessment using femur length.</p></div><div><h3>Methods</h3><p>A cross-sectional study conducted in 11 healthcare facilities across four districts in Zambia involved the evaluation of 928 images captured during the implementation of the Training in Ultrasound to Determine Gestational Age (TUDA) program in 2021. TUDA, collaboration under the DIPLOMATIC Study, trained 24 midwives intensively for 14 days, followed by eight weeks of supervised scanning. Image assessment utilized the Sarries four-point tool, and statistical analyses included descriptive and inferential statistics.</p></div><div><h3>Results</h3><p>Midwives achieved an 87.95 % competency level in basic ultrasound scans for gestational age determination using femur length. Assessment by four evaluators showed an average proportion of good-quality images also at 87.95 %. There were no statistically significant differences among assessors, indicating consistency in evaluations. Trainers and radiographers exhibited different average proportions of good-quality images at 91.5 % and 83.9 %, respectively, with no statistically significant differences observed between them.</p><p>Furthermore, analysis of image quality revealed significant variation among different facilities. Specifically, in Chipata, 24.32 % of scans were classified as poor quality, while in George Clinic, only 2.30 % were considered poor quality. A Chi-square test indicated a substantial correlation between health facility and image quality (χ<sup>2</sup> = 15.99, p = 0.025). However, no significant correlations were found between image quality and factors such as work experience, age group, or gender.</p></div><div><h3>Conclusion</h3><p>This study provides critical evidence for successfully training midwives to competent produce high-quality ultrasound images for determining gestational age. These findings are essential for guiding interventions aimed at enhancing ultrasound service delivery and ensuring consistent, high-quality healthcare outcomes, because this is critical for effective prenatal care in Zambia. This has high potential to improve prenatal care.</p></div><div><h3>Recommendation</h3><p>Zambia needs to train more midwives to provide routine ultrasound services during Antenatal Care (ANC) which may ultimately reduce preterm and still births. We recommend the inclusion of ultrasound scanning in-service and pre-service training and establishment of standardized protocols and guidelines for ultrasound scanning services during antenatal clinics.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100057"},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000259/pdfft?md5=1e6e884893ae74abbd964869ad0fda89&pid=1-s2.0-S2949668324000259-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roxane Munsterman , Tim Boers , Sicco J. Braak , Jelmer M. Wolterink , Michel Versluis , Srirang Manohar
{"title":"Deep learning-based segmentation of 3D ultrasound images of the thyroid","authors":"Roxane Munsterman , Tim Boers , Sicco J. Braak , Jelmer M. Wolterink , Michel Versluis , Srirang Manohar","doi":"10.1016/j.wfumbo.2024.100055","DOIUrl":"10.1016/j.wfumbo.2024.100055","url":null,"abstract":"<div><p>The goal of the study was to develop a method for segmentation of the thyroid, carotid artery (CA), and jugular vein (JV) using 3D ultrasound data. This method forms the basis for a computer-assisted needle-based intervention for thyroid nodules and thyroid volume estimation accuracy. Two datasets were used: the first was acquired using a tracked 2D sweep and the second with a 3D matrix transducer. A 2D and 3D U-Net model were trained on the full data set with different strategies (2D, majority vote in 2.5D and 3D). The 2D model achieved the best results for the tracked 2D sweep data set in terms of median Dice Score Coefficient (DSC) (0.934, 0.924, 0.897) and Hausdorff distance at the 95 percentile (HD<sub>95</sub>) (1.206, 0.588, 1.571 mm) for the thyroid, CA, and JV, respectively. For the matrix data set, the 3D model gave overall the best results in its median DSC (0.869, 0.930, 0.856) and HD<sub>95</sub> (1.814, 0.606, 1.405 mm) for the thyroid, CA, and JV, respectively, showing comparable results in vessel segmentation but inferior results in thyroid segmentation compared to the tracked sweep data set. The model demonstrated lower median volume estimation errors in the tracked sweep data set (4.45 %) compared to the matrix data set (7.40 %) and the ellipsoid formula (13.84 %) for thyroid volume estimation. This work shows that automatic segmentation in 3D ultrasound of the human neck is best performed with 3D ultrasound. Improving the quality of the 3D data is important for the development of a planning and navigation method to be used with needle-based interventions for thyroid nodules.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100055"},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000235/pdfft?md5=33e77984ac9b8fcd628e6b4f206b9cf2&pid=1-s2.0-S2949668324000235-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141709610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meijun Zhou , Jialin Ye , Sushu Li , Wenhong Yi , Yu Wang , Jiangting Ji , Tianyue Wang , Yi Yin , Yanni He , Hongmei Liu
{"title":"Diagnostic value of sonographic signs in acute injury of anterior talofibular ligament","authors":"Meijun Zhou , Jialin Ye , Sushu Li , Wenhong Yi , Yu Wang , Jiangting Ji , Tianyue Wang , Yi Yin , Yanni He , Hongmei Liu","doi":"10.1016/j.wfumbo.2024.100056","DOIUrl":"10.1016/j.wfumbo.2024.100056","url":null,"abstract":"<div><h3>Objectives</h3><p>The present study aimed to determine the diagnostic value of sonographic signs in patients who have experienced an acute injury of the anterior talofibular ligament (ATFL), and provide diagnostic evidence for improving the classification of ATFL injuries.</p></div><div><h3>Methods</h3><p>We retrospectively analyzed a total of 158 ATFL injuries, confirmed by surgery or magnetic resonance imaging (MRI), in 157 patients (one patient had bilateral ankle injury). A group of senior radiologists, along with two junior radiologists, identified the direct and indirect sonographic signs of ATFL injuries on ultrasound (US) images, and determined the ATFL injury classification. We then compared the diagnostic accuracy of the ATFL injury classifications, as well as the consistency of sonographic sign identification, between the senior radiologist group and the two junior radiologists. The sonographic signs identified by the senior radiologist group were used as the standard by which we analyzed the diagnostic efficacy of each sonographic sign for ATFL injury classification.</p></div><div><h3>Results</h3><p>The diagnostic accuracy for complete ATFL tears was 88.5 % in the senior radiologist group, which was higher than that for the two junior radiologists (72.3 % and 67.7 %). Compared to the senior radiologist group, the consistency between the two junior radiologists in identifying all sonographic signs of ATFL injuries was low (kappa value < 0.75). Most complete tear, partial tear, and sprain/normal ATFL showed ligament thickening and were predominantly hypoechoic, but there were significant differences in ligament tension, clarity, and continuity (<em>P</em> < 0.05). The sensitivity of direct sonographic signs alone in the diagnosis of complete ATFL tears reached 100 %, and the positive predictive value, negative predictive value, and accuracy rate were all > 80 %. Direct sonographic signs were further combined with indirect sonographic signs to improve the diagnostic specificity and positive predictive value for the diagnosis of ATFL injuries.</p></div><div><h3>Conclusions</h3><p>High-frequency US is the first choice for the diagnosis of ATFL injuries; however, radiologists with different levels of experience may classify ATFL injuries differently. Refined sonographic signs, especially ligament tension, clarity, and continuity, are helpful in the classification and diagnosis of ATFL injuries and provide guidance for the treatment and management of ankle injuries in clinical practice.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100056"},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000247/pdfft?md5=05dde5b3d2a59adfe42be5124b536b80&pid=1-s2.0-S2949668324000247-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141701331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Le Chong , Luhua Xia , Xiulan Wu , Hongyu Li , Zhiying Jia
{"title":"Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis","authors":"Le Chong , Luhua Xia , Xiulan Wu , Hongyu Li , Zhiying Jia","doi":"10.1016/j.wfumbo.2024.100054","DOIUrl":"10.1016/j.wfumbo.2024.100054","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the accuracy of contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer.</p></div><div><h3>Methods</h3><p>PubMed, EMBASE, The Cochrane Library, Chinese Biomedical Literature Database, the full database of China, Chinese National Knowledge Infrastructure, and Wanfang database databases were utilized. Perspective studies regarding CEUS diagnosis of axillary lymph nodes in breast cancer were included. QUADAS-2 was used to estimate the research quality by two reviewers independently. Metadisc1.4 software and Stata 14.0 were used to examine data from the included studies. The diagnostic value of CEUS was assessed by aspects such as summary sensitivity, specificity, receiver operating characteristic (SROC).</p></div><div><h3>Results</h3><p>Fourteen studies were included and 1127 patients were included. A meta-analysis showed that the summary sensitivity of CEUS was 0.85 (95 % CI 0.82–0.87), the specificity was 0.86 (95 % CI 0.82–0.89), the diagnostic odds ratio was 31.15 (95 % CI 17.16–56.52) and the SROC was 0.9186.</p></div><div><h3>Conclusions</h3><p>CEUS diagnosis of axillary lymph nodes in breast cancer has high sensitivity and specificity and it is the preferred method to diagnose axillary lymph nodes in breast cancer in clinical practice.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100054"},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000223/pdfft?md5=a45010cf49a4fd869067f9cdcdfcdb6f&pid=1-s2.0-S2949668324000223-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141629935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anas Elgenidy , Ramez M. Odat , Mohamed Hesn , Asmaa Abodaif , Mohamed S. Elgendy , Mohammad Alzu'bi , Abdelrahman R. Youssef , Shady Sapoor , Mahmoud Mohamed AlSanafini , Moustafa Elnewishy , Paula Gamal Wassef
{"title":"Ultrasound for evaluating gastrointestinal symptoms in irritable bowel syndrome patients: A systematic review","authors":"Anas Elgenidy , Ramez M. Odat , Mohamed Hesn , Asmaa Abodaif , Mohamed S. Elgendy , Mohammad Alzu'bi , Abdelrahman R. Youssef , Shady Sapoor , Mahmoud Mohamed AlSanafini , Moustafa Elnewishy , Paula Gamal Wassef","doi":"10.1016/j.wfumbo.2024.100053","DOIUrl":"https://doi.org/10.1016/j.wfumbo.2024.100053","url":null,"abstract":"<div><h3>Introduction</h3><p>Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder with unclear pathogenesis, characterized by diverse symptoms such as bloating, abdominal pain, and altered bowel habits. Medical imaging, particularly ultrasound, has gained importance in diagnosing and managing IBS due to its non-invasiveness and affordability. We aim to evaluate the utility of ultrasound (US) in diagnosing and monitoring IBS by assessing various aspects such as intestinal motility, gallbladder function, urinary bladder, gastric function, autonomic dysfunction, and vagus nerve assessment.</p></div><div><h3>Methods</h3><p>Studies were collected from PubMed, Scopus, Cochrane, Embase, and the Web of Science. Eligible studies were selected based on the inclusion criteria. Data extraction covered study characteristics (such as country, US device type, patients, age, site of US evaluation, and dyspepsia) and the role of the US in bowel-wall thickness, sigmoid colon motility, gallbladder function, gastric function, autonomic dysfunction, and vagus nerve assessment.</p></div><div><h3>Results</h3><p>Twenty studies were included, encompassing diverse ultrasound modalities and patient populations. Ultrasound showed promise in assessing bowel-wall thickness, sigmoid colon motility, gallbladder function, gastric function, autonomic dysfunction, and vagus nerve assessment in IBS patients. Notably, ultrasound demonstrated potential for distinguishing between IBS and inflammatory bowel disease (IBD) and aiding in disease prediction and severity assessment.</p></div><div><h3>Conclusion</h3><p>This comprehensive review underscores the value of ultrasound in diagnosing and managing IBS, offering insights into its diverse applications and diagnostic accuracies across various aspects of gastrointestinal function. However, further research is warranted to address the limitations and optimize the diagnostic accuracy of ultrasound in IBS management.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100053"},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000211/pdfft?md5=78dd76fc12350a5bb8562535ff663aba&pid=1-s2.0-S2949668324000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Appropriate body position and site for diaphragm ultrasound: Comparison with inspiratory mouth pressure","authors":"Kazunori Okada , Akiko Kamiya , Yusuke Yanagi , Masahiro Nakabachi , Yasuhiro Hayashi , Michito Murayama , Sanae Kaga","doi":"10.1016/j.wfumbo.2024.100052","DOIUrl":"https://doi.org/10.1016/j.wfumbo.2024.100052","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to examine the appropriate body position and anatomical site for DUS through comparisons with maximal inspiratory pressure (MIP).</p></div><div><h3>Methods</h3><p>Thirty healthy adults were included in the study. MIP was measured using a spirometer. DUS was performed in both the right and left intercostal spaces in both sitting and supine positions. The diaphragm thickness at functional residual volume (TD<sub>FRC</sub>) and total lung capacity (TD<sub>TLC</sub>) were measured, and the fractional change in diaphragm thickness (TF) was calculated under each condition. To assess interobserver reproducibility, DUS was performed by an experienced examiner and a novice examiner.</p></div><div><h3>Results</h3><p>Among the DUS parameters, the TD<sub>FRC</sub> measured at the right intercostal space in the sitting position showed the strongest correlation with MIP (r = 0.68, p < 0.001). The correlations of TD<sub>TLC</sub> with MIP tended to be inferior to those of TD<sub>FRC</sub> with MIP, and the TF parameters did not correlate significantly with MIP. DUS measurements in the supine position demonstrated greater reproducibility than those in the sitting position, and those at the right intercostal space tended to be better than those at the left intercostal space.</p></div><div><h3>Conclusion</h3><p>When evaluating respiratory muscle function during inspiration using DUS, TD<sub>FRC</sub> at the right zone of the apposition in the sitting position was found to be appropriate. DUS measurements at the right zone of apposition in the supine position were considered adequate for clinical use because the influence of examiner experience was small.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100052"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S294966832400020X/pdfft?md5=d7a881a506b6171e9ffccbb8569d4a89&pid=1-s2.0-S294966832400020X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141483873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine Paverd , Alexander Martin , Marga Rominger , Lisa Ruby
{"title":"Assessment of ultrasound image quality in a reference phantom using gel and liquid standoff pads","authors":"Catherine Paverd , Alexander Martin , Marga Rominger , Lisa Ruby","doi":"10.1016/j.wfumbo.2024.100051","DOIUrl":"https://doi.org/10.1016/j.wfumbo.2024.100051","url":null,"abstract":"<div><h3>Background</h3><p>and Methods: This paper presents a review of image quality in ultrasound imaging when using gel and liquid standoff pads, compared to imaging without a standoff pad. Imaging metrics assessed are lateral resolution, nearfield target intensity, and contrast to noise ratio of echogenicity targets. Measurements were made with a Canon Aplio i800 ultrasound system on a standardized ultrasound phantom (Computerized Imaging Reference Systems, Inc.), and custom-made agarose phantoms. Two cases are examined: when the ultrasound images are taken with the probe at different heights above the phantom (the normal clinical use-case for standoff pads); and when the ultrasound probe is artificially always placed at the same height above the phantom (allowing for direct image comparison).</p></div><div><h3>Results and conclusion</h3><p>The main differences in the standard clinical use-case were observed in nearfield image intensity, with a mean difference of 22.4 ± 11.1 % between highest and lowest positions. Investigation of probes at the same height above the phantom shows that differences appear to be due primarily due to the height of the probe above the phantom, rather than the pads themselves. Elevational beamwidth was found to be a minimum of 2.2 mm at 25 mm axial depth, and adding a standoff pad can change vessel and cyst visualization due to the elevational beamwidth. This is a useful result to be aware of for clinicians using standoff pads on modern ultrasound systems.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100051"},"PeriodicalIF":0.0,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000193/pdfft?md5=285c2f529ffa468781058da53ccb26e2&pid=1-s2.0-S2949668324000193-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141540698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam Lim , Mohamed Abdalla , Farbod Abolhassani , Wyanne Law , Benjamin Fine , Dafna Sussman
{"title":"Automatic standard plane and diagnostic usability classification in obstetric ultrasounds","authors":"Adam Lim , Mohamed Abdalla , Farbod Abolhassani , Wyanne Law , Benjamin Fine , Dafna Sussman","doi":"10.1016/j.wfumbo.2024.100050","DOIUrl":"https://doi.org/10.1016/j.wfumbo.2024.100050","url":null,"abstract":"<div><h3>Objective</h3><p>This study introduces an innovative end-to-end deep learning pipeline designed to automatically classify and order fetal ultrasound standard planes in alignment with the guidelines of the Canadian Association of Radiologists, while also assessing the diagnostic usability of each view. The primary objective is to address the manual and cumbersome challenges that interpreting radiologists encounter in the existing obstetric ultrasound workflow.</p></div><div><h3>Methods</h3><p>We compiled a diverse dataset, comprising 33,561 de-identified two-dimensional obstetrical ultrasound images acquired from January 1, 2010, to June 1, 2020. This dataset was categorized into 19 distinct classes associated with standard planes and further partitioned into training, validation, and testing subsets via a 60:20:20 stratified split. The standard plane and diagnostic usability networks are founded on a convolutional neural network framework and employ the benefits of transfer learning.</p></div><div><h3>Results</h3><p>The standard plane classification network demonstrated promising results by achieving 99.4 % and 98.7 % for accuracy and F1 score, respectively. Subsequently, the diagnostic usability network demonstrated strong performance, registering 80 % accuracy and an 82 % F1 score. Notably, this study is the first to investigate whether deep learning methods can surpass sonographers in the standard plane labeling task, with some instances revealing the algorithm's capacity to rectify sonographer mislabeled planes.</p></div><div><h3>Conclusion</h3><p>The results highlight the algorithm's potential to be integrated into a clinical setting by serving as a reliable assistive tool, alleviating the cognitive workload faced by radiologists and enhancing efficiency and diagnostic outcomes in the current obstetric ultrasound process.</p></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"2 2","pages":"Article 100050"},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949668324000181/pdfft?md5=6d1b4a97d145109fa7f438f96a49ba42&pid=1-s2.0-S2949668324000181-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}