WFUMB Ultrasound Open最新文献

{"title":"Reflections on CGAA module for fetal torso ultrasound plane identification: Image parameters, interpretability, and dataset adaptation","authors":"Sanglin Zhao , Måns Gustaf","doi":"10.1016/j.wfumbo.2025.100098","DOIUrl":"10.1016/j.wfumbo.2025.100098","url":null,"abstract":"","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 2","pages":"Article 100098"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145415814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Twinkling artifact: a novelty finding for gel bleeding in silicone induced granuloma of breast implant capsule","authors":"Giulia Matheus e Castro ,&nbsp;Eduardo de Faria Castro Fleury","doi":"10.1016/j.wfumbo.2025.100091","DOIUrl":"10.1016/j.wfumbo.2025.100091","url":null,"abstract":"<div><div>The Twinkling artifact is an ultrasound finding commonly observed for the diagnosis of urolithiasis. The artifact consists of the formation of noise in the Doppler flowmetry study. However, when it comes to the evaluation of breast implants, there is no reported evidence in literature concerning its presence and significance.</div><div>In this case report, we describe a 41-year-old patient with implants for 8 years, asymptomatic, but who undergoes regular screening exams. In the Doppler ultrasound, the twinkling artifact was detected unilaterally inside an intracapsular mass compatible with silicone-induced granuloma of breast implant capsule (SIGBIC).</div><div>The objective of this case report is to demonstrate the strong correlation between the twinkling artifact and the presence of the silicone, foreign body. Specifically, when this artifact appears within the fibrous capsule, it strongly suggests gel bleeding. Therefore, the twinkling artifact can serve as an early sign of silicone bleeding in intact breast implants.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 2","pages":"Article 100091"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating long-term skill retention following teledidactic vs. on-campus musculoskeletal ultrasound training: The TELMUS-follow-up study","authors":"Ricarda Neubauer ,&nbsp;Claus-Juergen Bauer ,&nbsp;Simon Michael Petzinna ,&nbsp;Pantelis Karakostas ,&nbsp;Elena Höhne ,&nbsp;Charlotte Behning ,&nbsp;Valentin Sebastian Schäfer ,&nbsp;Florian Recker","doi":"10.1016/j.wfumbo.2025.100092","DOIUrl":"10.1016/j.wfumbo.2025.100092","url":null,"abstract":"<div><h3>Purpose</h3><div>Musculoskeletal ultrasound (MSUS) relies on examiner competence, requiring ongoing practice, supervision, and quality assurance. Limited resources and densely packed medical curricula demand effective training methods to ensure long-term skill retention. Teledidatic as well as peer-assisted learning approaches have shown short-term results in training MSUS comparable with conventional in-class teaching. Consequently, this study aimed to evaluate the long-term retention of MSUS skills.</div></div><div><h3>Materials and methods</h3><div>One year after completing either the teledidactic or conventional course of a standardized MSUS elective (TELMUS study), medical students’ retention of MSUS skills in image acquisition and interpretation was assessed by a repeated objective structured clinical examination (OSCE). The follow-up OSCE scores of the teledidactic cohort and the on-campus cohort were compared to their previous results as well as between the two study groups.</div></div><div><h3>Results</h3><div>A total of 24 medical students of the initial 30 (80 %) participated in the follow-up study. In the follow-up OSCE, students enrolled in the teledidactic course achieved an average score of 52.88 (SD ± 6.12), which corresponds to 90.35 % of the results of the post-course assessment. Similarly, the on-campus participating students reached 91.99 % of their post-course OSCE with 52.25 (SD ± 7.45) points. No significant differences could be found between the two teaching cohorts (p &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>Teledidactic teaching formats lead to an equivalent long-term maintenance of practical MSUS skills and serve as a sustainable didactic approach in medical education. The observed decline in skills across both cohorts highlights the critical need for repetition in student ultrasound education, ideally integrated into a longitudinal curriculum.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 2","pages":"Article 100092"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of congenital heart diseases in children from 2D and 3D sonography using convolutional neural networks: A scoping literature review","authors":"Ayiga Majid ,&nbsp;Johnes Obungoloch ,&nbsp;Alfred Enywaku ,&nbsp;Obeti Francis ,&nbsp;Denis Jjuuko ,&nbsp;Eugene Bizimana ,&nbsp;Biryomumeisho Joshua ,&nbsp;Wasswa William","doi":"10.1016/j.wfumbo.2025.100096","DOIUrl":"10.1016/j.wfumbo.2025.100096","url":null,"abstract":"<div><div>Congenital heart diseases (CHDs) are the commonest congenital anomalies and a leading cause of neonatal morbidity and mortality worldwide. They affect approximately 1 % of live births globally. Prenatal detection with fetal echocardiography allows for timely referral and intervention. However, screening performance remains uneven because of operator dependence and resource limits. Convolutional neural networks (CNNs) offer automated image interpretation and have been widely applied to 2D and 3D fetal ultrasound (US) in recent years.</div><div>This scoping review maps CNN applications for prenatal CHD across 2010–September 2025. In adherence to the PRISMA-ScR methodology, we screened 845 records from PubMed, IEEE Xplore, Google Scholar, ScienceDirect and preprint servers and included 29 studies for synthesis. The volume of articles published on the topic rose sharply after 2020, with most datasets drawn from Asia and North America and no representation from sub-Saharan Africa. The most commonly reported architectures were DenseNet variants, U-Net families for segmentation, YOLO (You Only Look Once) variants for real-time detection, and ensemble hybrids for classification.</div><div>Reported internal performance is high in many studies, with top models achieving near-expert discrimination with AUCs (Area Under the Curve) up to 0.99. In our cohort, the mean AUC across studies reporting that metric was 0.911 (Standard Deviation-SD = 0.09; 95 % CI: 0.86–0.96; n = 11). Average sensitivity and specificity across studies reporting these metrics were 0.92 (SD = 0.04; n = 13) and 0.91 (SD = 0.04; n = 7), respectively. However, external and multi-centre validation remains limited, and performance commonly falls when models are tested on unseen centers or different scanner types. Methodological gaps include small or imbalanced lesion classes, inconsistent patient-level splitting, sparse reporting of deployment constraints, and limited fairness analyses.</div><div>Recent work shows promising directions such as multimodal fusion of B-mode and Doppler, lightweight networks, on-device optimization, federated and privacy-preserving training, and prospective protocols for multi-centre evaluation. To translate CNNs into clinical screening, we recommend coordinated efforts to build diverse, well-annotated repositories, adopt strict patient-level validation and external testing, report deployment metrics, and run prospective, pragmatic trials that measure clinical outcomes and health-economic impact. These steps can move CNNs from high-performance demonstrations to dependable tools that improve prenatal CHD detection equitably.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 2","pages":"Article 100096"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145324295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of superficial high-frequency ultrasonography in assessing vulvovaginal lesions: A retrospective study","authors":"Kakoly Borthakur","doi":"10.1016/j.wfumbo.2025.100089","DOIUrl":"10.1016/j.wfumbo.2025.100089","url":null,"abstract":"<div><h3>Objective</h3><div>Ultrasound is a well-established imaging modality for assessing the female pelvis and perineum, primarily using convex or transvaginal probes. However, the vulvar region, being superficially located, remains inadequately evaluated by conventional ultrasound techniques. This study aims to explore the efficacy of superficial linear high-frequency ultrasonography, employing a targeted trans-perineal approach, in detecting and characterizing vulvovaginal lesions.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed 61 patients presenting with clinical symptoms of pain or swelling in the vulvar region. Superficial high-resolution linear ultrasound was utilized as the primary diagnostic tool, with convex and intracavitatory probes employed in select cases. The ultrasound findings were correlated with clinical assessments, surgical outcomes, and pathological results.</div></div><div><h3>Results</h3><div>The ultrasound findings demonstrated a diagnostic accuracy of 95 % (CI - 89.5 %). Notably, 78.6 % of patients were treated based solely on ultrasound findings. While some cases underwent further evaluation with Magnetic Resonance Imaging (MRI), the additional findings did not significantly alter management or treatment outcomes. The predominant lesions identified were cystic in nature, originating from the vulva, vagina, or urethra, with most cases being acute inflammatory or infective lesions necessitating urgent medical intervention.</div></div><div><h3>Conclusion</h3><div>This study underscores the potential of ultrasound in the diagnosis and management of vulvar and superficial perineal lesions. The findings support the use of superficial high-frequency ultrasonography as a valuable tool in the morphological assessment of vulvovaginal lesions, facilitating timely diagnosis and treatment. This approach can potentially reduce healthcare costs and improve patient outcomes for those suffering from acute conditions, ultimately leading to improved clinical outcomes.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 2","pages":"Article 100089"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic determination of bifurcation site of the tibial nerve at the tarsal tunnel","authors":"Donald Spears Wilcox ,&nbsp;Antonio Tom Howard ,&nbsp;Mark S. Mennemeier ,&nbsp;Jacqueline Rainey ,&nbsp;Charlotte Yates ,&nbsp;Melissa Allen ,&nbsp;Kevin D. Phelan","doi":"10.1016/j.wfumbo.2025.100090","DOIUrl":"10.1016/j.wfumbo.2025.100090","url":null,"abstract":"<div><h3>Objective</h3><div>Variability of Tibial nerve branching patterns with regard to the tarsal tunnel and malleolar-calcaneal axis has been established in a limited number of cadaveric studies with relatively few subjects. The current study used high-resolution ultrasonography to investigate tibial nerve branching variability, in-vivo, from a large number of healthy subjects.</div></div><div><h3>Methods</h3><div>High resolution ultrasonography was used to map the course of the tibial nerve, to determine the bifurcation point into to medial and lateral plantar nerves with regard to the malleolar-calcaneal axis and the tarsal tunnel, and to classify them into one of five established branching patterns. The in-vivo, ultrasonography findings were then compared with findings from cadaveric studies.</div></div><div><h3>Results</h3><div>The ultrasonography data for 156 feet (78 subjects-40 male, 38 female) of young, healthy individuals produced results similar to the cadaveric data with only small differences in each branching classification. Additionally, variation in the type of branching patterns between the left and right legs was observed in 23 % of the sample (i.e., 18 of 78 subjects).</div></div><div><h3>Conclusions</h3><div>In-vivo, high-resolution ultrasound appears to be a valid approach for investigating anatomic variation of superficial nerves as the US data converge with those for cadaveric dissection. Further, not only were the percentages of branching pattern types replicated from earlier cadaveric studies, but also differences in the types of branching patterns between the left and right legs of the same subjects were observed in 23 % of the sample. A side-to-side difference of this type has not been previously reported. Finally, a decided advantage of using ultrasound to map nerve branching, when possible, is that it is easier to obtain a larger sample than in typical cadaveric studies. The current study more than doubled the number of specimens collected in previous cadaveric studies which greatly improves the external validity of our findings.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 2","pages":"Article 100090"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Induction of an anti-tumor immune response by sonodynamic therapy, combining 5-aminolevulinic acid and high-intensity focused ultrasound using the trigger pulse sonication","authors":"Tohru Satoh ,&nbsp;Rui Tada ,&nbsp;Taiki Yamaguchi ,&nbsp;Yoko Endo-Takahashi ,&nbsp;Takashi Kanno ,&nbsp;Mai Hayakawa ,&nbsp;Yoshiyuki Adachi ,&nbsp;Yoichi Negishi ,&nbsp;Jun Okamoto ,&nbsp;Shin Yoshizawa ,&nbsp;Ken Masamune","doi":"10.1016/j.wfumbo.2025.100088","DOIUrl":"10.1016/j.wfumbo.2025.100088","url":null,"abstract":"<div><div>Ultrasound-based cancer therapies offer non-invasive treatment options for deep-seated tumors, yet their clinical application is often limited by safety concerns. High-intensity focused ultrasound (HIFU) has demonstrated therapeutic potential, but its high-power requirements can damage surrounding healthy tissues, particularly near sensitive structures such as the gastrointestinal tract. The optimal balance between therapeutic efficacy and safety remains a significant challenge in ultrasound-based cancer treatment. Here we show that combining 5-aminolevulinic acid (5-ALA)-mediated sonodynamic therapy (SDT) with a novel HIFU system achieves effective tumor suppression at reduced acoustic intensities while enhancing anti-tumor immune responses. This novel system features the use of a trigger HIFU sequence that enables precise control over cavitation bubbles within the target tissue. In a murine colon carcinoma model, this approach demonstrated significant tumor growth inhibition with single-session treatment comparable to multiple HIFU sessions, while increasing tumor infiltration by activated CD8⁺ T cells and antigen-presenting dendritic cells. These findings extend beyond previous studies by revealing that SDT not only enables effective tumor treatment at lower, safer acoustic intensities but also promotes beneficial immune responses that could enhance therapeutic outcomes. This combination of reduced treatment intensity, shortened duration, and immune system activation suggests potential applications for treating tumors in anatomically sensitive locations. The demonstrated immunological effects also indicate possible synergies with existing cancer immunotherapies, potentially expanding treatment options for patients with deep-seated solid tumors.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 2","pages":"Article 100088"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Added clinical advantage of combining ultrasound with radiograph in assessing ankle injuries: Comparison with MRI","authors":"Yanni He ,&nbsp;Wenhong Yi ,&nbsp;Chenqian Guo ,&nbsp;Wenjun Li ,&nbsp;Changpeng Xu ,&nbsp;Jialin Ye ,&nbsp;Sushu Li ,&nbsp;Meijun Zhou ,&nbsp;Tong Bai ,&nbsp;Tong Wang ,&nbsp;Lixian Liu ,&nbsp;Ning Zhang ,&nbsp;Yu Wang ,&nbsp;Jingjiao Xu ,&nbsp;Hongmei Liu","doi":"10.1016/j.wfumbo.2025.100081","DOIUrl":"10.1016/j.wfumbo.2025.100081","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the diagnostic accuracy of ultrasound (US) and magnetic resonance imaging (MRI) for ankle ligament injuries, and evaluate ankle injury using the combination of US and X-ray.</div></div><div><h3>Materials and methods</h3><div>A retrospective study was conducted on 1419 participants presenting with ankle injury at hospital between July 2020 and March 2022. 1153 patients included after exclusion underwent US imaging, while 584 patients were also diagnosed by X-ray and 78 accepted MRI. The diagnostic abilities of MRI and US for ankle ligamentous injuries (anterior inferior tibiofibular ligament (AITFL), anterior talofibular ligament (ATFL), calcaneofibular ligament (CFL), medial deltoid ligament (MDL)) were compared by Wilcoxon signed-rank test. The diagnostic performance of US for ligamentous tear was evaluated in terms of sensitivity, specificity, and AUC value, with MRI as the reference standard. The detection rates of X-ray imaging, US imaging, and their combination were compared by Kendall's W test and Wilcoxon signed-rank test.</div></div><div><h3>Results</h3><div>The study population included 558 males and 595 females with a mean age of 30 ± 13 years. There were no significant differences on the grade of ligament injury detected by US and MRI (P _AITFL = 0.52, P _ATFL = 0.15, P _CAL = 0.061, P _MDL = 0.26). The diagnostic sensitivity, specificity and AUC of US imaging for ligamentous tear were 50.0 %, 88.9 % and 0.69 in AITFL, 92.7 %, 60.9 % and 0.77 in ATFL, 90.9 %, 86.6 % and 0.89 in CFL, 66.7 %, 96.0 % and 0.81 in MDL respectively. The detection rate of bone fracture increased significantly after combining US and X-ray imaging (R _{US &amp; x-ray} = 42.6 %, R _US = 36.5 %, R _x-ray = 26.5 %, P &lt; 0.0001).</div></div><div><h3>Conclusion</h3><div>US imaging showed similar diagnostic performance for AITFL, ATFL, CFL and MDL injury as MRI. The combination of US and X-ray imaging can be a useful complementary tool for primary evaluation of ankle injuries.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 1","pages":"Article 100081"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of evoked vibrational signatures under ultrasound examination as a novel method of tissue classification","authors":"Baxton R. Chen","doi":"10.1016/j.wfumbo.2024.100078","DOIUrl":"10.1016/j.wfumbo.2024.100078","url":null,"abstract":"<div><h3>Background</h3><div>Ultrasound interpretation requires extensive training and can be subjective and inexact. We previously reported a novel method of identifying tissues by analyzing the evoked vibrational signatures based on inherent tissue structural integrity and density during ultrasound examination. We now demonstrate the evoked tissue vibrational signatures of different tissues.</div></div><div><h3>Results</h3><div>During ultrasound examination, the evoked vibrational signatures are detected by a portable dynamic signal recorder and interpreted based on time, amplitude, dampening, and frequency on single or multiple degrees of freedom. Various organs and tissue types were examined using ultrasound and unique vibrational signatures were recorded and stored in a proprietary database. Representative signatures of liver, kidney, lungs, and muscles were demonstrated, and their vibration frequencies and amplitudes were compared.</div></div><div><h3>Conclusion</h3><div>We developed a method of using vibrational signatures to identify tissues under ultrasound examination, and we now report the signatures of different tissue types.</div></div>","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 1","pages":"Article 100078"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143160096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A proposal to use bubble exposure time instead of bubble count to grade PFOs","authors":"Ruud W. Keunen,&nbsp;Mark M. Rubin,&nbsp;Emily Ho","doi":"10.1016/j.wfumbo.2024.100077","DOIUrl":"10.1016/j.wfumbo.2024.100077","url":null,"abstract":"","PeriodicalId":101281,"journal":{"name":"WFUMB Ultrasound Open","volume":"3 1","pages":"Article 100077"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143127955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}