Daniel Pleissner , Nicole Händel , Stephanie Schönfelder , Janos-Istvan Petrusan , Beatriz Queiroz Silva , Jens Schröder , Josef Müller , Keith Cowan , Sergiy Smetana
{"title":"Long-term heterotrophic cultivation of Galdieria sulphuraria at technical scale under non-sterile conditions","authors":"Daniel Pleissner , Nicole Händel , Stephanie Schönfelder , Janos-Istvan Petrusan , Beatriz Queiroz Silva , Jens Schröder , Josef Müller , Keith Cowan , Sergiy Smetana","doi":"10.1016/j.scowo.2025.100116","DOIUrl":"10.1016/j.scowo.2025.100116","url":null,"abstract":"<div><div>The transition to a sustainable bioeconomy relies on efficient conversion of biomass and industrial side-streams into value-added products. This study evaluates the heterotrophic cultivation of the extremophilic microalga <em>Galdieria sulphuraria</em> using a decentralized, 200 L-scale bioreactor system, testing alternative nutrient sources including glycerol, molasses, and hydrolysates from brewer’s spent grains. The growth performance, yield, and compositional robustness under these complex substrates were compared with a defined medium containing glucose, ammonium, and phosphate. <em>G. sulphuraria</em> demonstrated robust growth across all tested substrates, reaching biomass concentrations between 10 and 26 g L<sup>−1</sup> in semi-continuous operation for over 40 days under acidic and thermophilic conditions. While defined medium supported higher productivity (0.4 kg day<sup>−1</sup>) and consistent nutrient supply, complex substrates derived from agro-industrial residues enabled substantial biomass formation (0.1–0.2 kg day<sup>−1</sup>) but required careful management of nutrient balance and potential inhibitory by-products such as acetic and lactic acids from molasses. Biomass analysis revealed variable macromolecular content depending on the substrate, with protein levels between 25 % and 42 % (w/w) and carbohydrates and lipids ranging broadly. The findings highlight the technical feasibility and adaptability of <em>G. sulphuraria</em> for decentralized conversion of waste streams, supporting more resilient and distributed models of resource valorization within the bioeconomy. Further optimization of substrate processing and system integration is recommended to improve productivity and scalability.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"8 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nur Aifa Fadil , Siti Nursyazweena Zul-kharnain , Mohamad Syafiq Abdul Wahab , Anca Awal Sembada , Mohamed Syazwan Osman , Nur Sakinah Burhan , Alia Khalidah Ismail
{"title":"Advancing green chemistry through ultrasound-assisted extraction of flavonoids from Moringa oleifera using response surface methodology","authors":"Nur Aifa Fadil , Siti Nursyazweena Zul-kharnain , Mohamad Syafiq Abdul Wahab , Anca Awal Sembada , Mohamed Syazwan Osman , Nur Sakinah Burhan , Alia Khalidah Ismail","doi":"10.1016/j.scowo.2025.100115","DOIUrl":"10.1016/j.scowo.2025.100115","url":null,"abstract":"<div><div><em>Moringa oleifera</em> is widely recognized for its rich content of bioactive compounds, particularly flavonoids, which possess strong antioxidant properties beneficial for health and functional applications. Efficient extraction of these compounds is essential to support their industrial utilization. In this study, ultrasound-assisted extraction (UAE) was optimized using Response Surface Methodology (RSM) with Central Composite Design (CCD) to maximize the flavonoid yield from Moringa oleifera leaves. The effects of extraction temperature, time, and solvent-to-solid ratio were evaluated to identify optimal conditions. The optimal parameters. 30°C, 60 min, and a 20:1 solvent-to-solid ratio, resulted in a total flavonoid content of 378.06 mg QE/g, closely matching the predicted value of 379.82 mg QE/g, thus validating the robustness of the RSM-CCD model. Scanning electron microscopy (SEM) analysis of the spray-dried extract revealed dense, non-porous microparticles with irregular shapes and clustered surfaces. These structural characteristics suggest potential applications in food application and biodegradable films and coatings, though they may limit usage in controlled-release formulations. Compared to other plant sources and extraction methods, the optimized UAE approach produced superior flavonoid yields, confirming its efficiency and relevance for scalable functional material development.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"8 ","pages":"Article 100115"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145060621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustainable leather tanning: Evaluation of Aphanamixis polystachya extract as an eco-friendly alternative to conventional tanning agents","authors":"Md. Mojaharul Islam, Sumaiya Mim, Umme Habiba Bodrun Naher, Md. Abdul Mottalib","doi":"10.1016/j.scowo.2025.100114","DOIUrl":"10.1016/j.scowo.2025.100114","url":null,"abstract":"<div><div>Vegetable tanning agents have emerged as sustainable alternatives to chromium-based tanning, which generates hazardous waste harmful to ecosystems and human health. Although numerous plant-derived tannins have been studied, few meet commercial standards due to limitations in efficiency, quality, and extraction methods. This study investigates the potential of <em>Aphanamixis polystachya</em> bark extract as a novel vegetable tanning agent in comparison with conventional mimosa tannin. Among the solvents tested, methanol yielded the highest extraction efficiency (30.75 ± 1.45 %). The extract showed a pH of 4.02 ± 0.15, moisture content of 4.14 ± 0.12 %, and total tannin content of 115.34 mg/g—comparable to mimosa (114.25 mg/g) and slightly lower than quebracho (129.96 mg/g). Condensed tannin content (23.7 ± 1.92 %) also fell within the reported range of reference tannins. FTIR analysis confirmed functional groups essential for collagen interaction, and UV-Vis spectroscopy revealed a characteristic peak at 280 nm, indicative of catechin and tannic acid-like compounds. Leather tanned with the extract showed a shrinkage temperature of 82.67 ± 0.57 °C, tensile strength of 250.35 ± 0.77 kg/cm², and elongation of 41.67 ± 1.03 %. It also outperformed mimosa in tear resistance, grain distension (8.5 mm), and fracture resistance (22.81 ± 1.39 kg). No surface cracks appeared after 50,000 dry flexing cycles. TGA and SEM analyses confirmed the thermal stability and fiber integrity of the treated leather. Overall, <em>Aphanamixis polystachya</em> extract demonstrated strong tanning performance and eco-friendly characteristics, making it a promising alternative to conventional vegetable tanning agents.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"8 ","pages":"Article 100114"},"PeriodicalIF":0.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Green synthesis and bioactivity of peach hibiscus silver nanoparticles","authors":"Geetha Kezhukut Ravunni , Mercy Madhumitha Kings , Anbumalarmathi Jeyabaskaran , Aruna Sharmili Sundararaj , Mani Divya , Sekar Vijayakumar","doi":"10.1016/j.scowo.2025.100113","DOIUrl":"10.1016/j.scowo.2025.100113","url":null,"abstract":"<div><div>Petals of peach hibiscus (<em>Hibiscus rosa-sinensis</em>) were used in the Synthesis of silver nanoparticles. The biosynthesized peach hibiscus silver nanoparticles (PH-AgNPs) were defined by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, Scanning Electron Microscopy (SEM) and Energy dispersive X-ray analysis (EDX). PH-AgNPs was validated by the color shift from pink to dark brown. UV–visible spectrophotometry (UV–vis) results showed a strong absorbance peak at 420 nm. XRD spectra confirmed the crystalline nature of the nanoparticles. FT-IR analysis confirmed the functional moieties responsible for the capping and stabilizing of AgNPs nanoparticles. SEM verified the nanoparticles spherical form, with an average size of 46.5 nm. The nature of the elements was found to be 60 % silver using EDX. Total phenolic content and flavonoid content in peaches hibiscus extract (PHE) was determined. Maximum radical scavenging efficacy of 99.82 % was observed in PH-AgNPs. The PH-AgNPs were found to possess potent antibacterial activity against <em>Klebsiella pneumonia</em>, <em>Escherichia coli, Enterococcus faecalis</em> and <em>Staphylococcus aureus.</em> PH-AgNPs showed potent antidiabetic activity and anti-inflammatory activities. Cytotoxicity was evaluated by larvicidal activity of <em>Artemia nauplii</em>. MTT assay of the PH-AgNPs showed potent inhibitory effect on the A549 lung cancer cell lines with the IC<sub>50</sub> value 50.070 ± 1.685 µg/mL.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"8 ","pages":"Article 100113"},"PeriodicalIF":0.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lithium-ion batteries and prospects for using biomass-derived carbon as electrode material - Overview","authors":"Sachin Channappa Hallad, N.L. Panwar","doi":"10.1016/j.scowo.2025.100112","DOIUrl":"10.1016/j.scowo.2025.100112","url":null,"abstract":"<div><div>High-power, high-energy-density electrochemical storage devices are essential for reducing fossil fuel dependence and enabling efficient renewable energy storage. Among various electrode materials, carbon remains a strong candidate due to its abundance, electrical conductivity, and tunable physicochemical properties. Biomass offers a renewable, low-cost, and sustainable route for producing carbon materials, drawing increasing attention for both environmental and energy applications. This review explores recent advancements in converting biomass into functional carbon for use as electrode materials in lithium-ion batteries (LIBs), particularly for electric vehicle (EV) applications. It summarizes diverse biomass sources, processing techniques, and structure property relationships, while addressing key challenges in scaling, performance optimization, and raw material sustainability. The transition from laboratory research to industrial application is discussed, including the potential of biomass carbon to reduce dependence on critical minerals. Finally, the review highlights emerging trends, integration with advanced battery technologies, and future perspectives for sustainable LIB development in EVs.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"8 ","pages":"Article 100112"},"PeriodicalIF":0.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Narasimha Raghavendra , Leena V. Hublikar , A.S. Sowmyashree , Suhas Basagonda Kale
{"title":"Investigation of acid-base indicator and antioxidant properties of beetroot and pomegranate peel extract","authors":"Narasimha Raghavendra , Leena V. Hublikar , A.S. Sowmyashree , Suhas Basagonda Kale","doi":"10.1016/j.scowo.2025.100111","DOIUrl":"10.1016/j.scowo.2025.100111","url":null,"abstract":"<div><div>An investigation into the indicator property of beetroot and pomegranate peel extract has been conducted. To obtain precise and trustworthy results for each of the four types of neutralization titrations such as strong acid (HCl) against strong base (NaOH), strong acid (HCl) against a weak base (NH<sub>4</sub>OH), weak acid (CH<sub>3</sub>COOH) against strong base (NaOH), and weak acid (CH<sub>3</sub>COOH) against weak base (NH<sub>4</sub>OH), the extracted pigments were used as an indicator. Monte Carlo (MC) simulation studies confirm the strong interaction between the plant extracted species and water molecules. A variety of analytical techniques was used to describe the green chemicals in the beetroot and pomegranate peel extract species. These techniques included FT-IR spectroscopy, optical profilometer, zeta potential and particle size analyzer. The beetroot and pomegranate peel extract antioxidant activity were also evaluated using the DPPH assay method. Plant extracts naturally contain highly colored substances called pigments, which can alter in response to changes in the pH and it is verified by spectral tests. The beetroot and pomegranate peel extract titrations' equivalency points are nearly identical to or coincide with those of the synthetic indicator (phenolphthalein) across all the titration types. The DPPH test findings demonstrated that the beetroot extract exhibited higher antioxidant activity than the pomegranate peel extract, with an IC50 value of 12. 31 mg/mL compared to 15.10 mg/mL for the pomegranate peel extract. The electron donation property of plant extract species was confirmed by using the DFT approach.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"8 ","pages":"Article 100111"},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144989684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sudha S. Patil , Vaibhavi Basavaraj Kulkarni , Narasimha Raghavendra
{"title":"Synthesis of gum ghatti- Andrographis paniculata flower extract-silver nanocomposite and its potential anticancer effects","authors":"Sudha S. Patil , Vaibhavi Basavaraj Kulkarni , Narasimha Raghavendra","doi":"10.1016/j.scowo.2025.100110","DOIUrl":"10.1016/j.scowo.2025.100110","url":null,"abstract":"<div><div>This work describes a sustainable process for the biogenic manufacture of silver nanocomposites (Ag NCs) that uses plant extract species as a capping and reducing agent. First time, the aqueous flower extract of Andrographis paniculata and gum ghatti was used in the current study to perform the biogenic production of silver nanocomposite. Uv-Visible, FT-IR, XRD and optical profilometer were among the methods used to analyze the produced gum ghatti- Andrographis paniculata extract-silver nanocomposite. Characterization results show the strong interaction between the Andrographis paniculata flower extract (APE), gum ghatti (GG) and silver cations in the aqueous environment. As a result of this, nano silver is formed. The findings of anti-lung cancer and anti-skin cancer studies demonstrated dose-dependent cytotoxicity, with greater doses exhibiting notable effects. With a low IC50 value of 35.56 ± 0.15 µg/ml, the cytotoxicity investigation employing the 3–4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay demonstrated that, gum ghatti- Andrographis paniculata flower extract-silver nanocomposites <strong>(</strong>GG-APE-Ag NCs) demonstrated substantial cytotoxicity to the National Cancer Institute - H460 (NCI-H-460) cell-line. An IC50 value of 67.45 ± 0.18 μg/ml was obtained from the cytotoxicity tests conducted on the A 375 skin cancer cell. In contrast to drugs that need larger dosages, a drug with a lower IC50 is more powerful and works at lower concentrations, which may result in less toxicity for patients and is efficient at destroying cancer cells. These results demonstrate the potential of biogenic GG-APE-Ag NCs as potent agents possessing anti -lung cancer and anti-skin cancer capabilities.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"7 ","pages":"Article 100110"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144988206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helen Rose J , Nidhin M , Parin Praveen , Ananya S. Agnihotri , Ganesan Krishnamoorthy
{"title":"Natural template-assisted green synthesis of cobalt oxide and its surface functionalization using β-alanine for biological applications","authors":"Helen Rose J , Nidhin M , Parin Praveen , Ananya S. Agnihotri , Ganesan Krishnamoorthy","doi":"10.1016/j.scowo.2025.100109","DOIUrl":"10.1016/j.scowo.2025.100109","url":null,"abstract":"<div><div>The incorporation of nanotechnology into material science has brought great advancements in diverse fields like medicine, electronics, energy, and the environment. Metal oxides gained notable attention from various nanomaterials due to their unique structure and properties. Cobalt oxide nanoparticles (Co<sub>3</sub>O<sub>4</sub>) stand out especially due to their diverse properties and applications. Synthesis of metal oxides through the traditional method faces many drawbacks, such as the use of toxic chemicals, a complex procedure, and environmental and health impacts. Whereas the green method of synthesis using natural resources, followed by surface modification with amino acids, acts as a better option for metal oxide synthesis. This paper focuses on developing a green, sustainable, and scalable method for synthesising Co<sub>3</sub>O<sub>4</sub> nanoparticles, using a natural template, gum Arabic, followed by surface functionalization of β-alanine. Various physico-chemical characterisation techniques such as DLS, TEM, FTIR and XRD were used to study nanoparticle composition and properties. Biocompatibility studies, cell viability assays and fibroblast cell lines from human skin by Alamar Blue assay, were carried out to test the effects of synthesised nanoparticles, and optimised protocols were also used to enhance performance for particular biomedical applications. Incorporating green synthesis and advanced techniques, β-alanine functionalized Co<sub>3</sub>O<sub>4</sub> nanoparticles, this research points toward developing more stable, biocompatible, and reactive nanoparticles under biological conditions. and multifunctional Co<sub>3</sub>O<sub>4</sub> nanomaterials. Overall, the current study aims at sustainability with innovation towards transformative various biological applications in healthcare, biomedicine, diagnostics, MRI, biosensors, photo-sensing agents and energy technologies while addressing significant gaps in present methodologies.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"7 ","pages":"Article 100109"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Azithromycin in the Sabarmati River as an indicator of aquatic environment contamination","authors":"Elisa Kalugendo , Prashant Singh , Rakhi Agarwal","doi":"10.1016/j.scowo.2025.100106","DOIUrl":"10.1016/j.scowo.2025.100106","url":null,"abstract":"<div><div>Azithromycin, a widely prescribed macrolide for respiratory infections, poses significant environmental risks due to its persistence in aquatic ecosystems. The study investigated the occurrence of azithromycin considering factors like, monthly and seasonal variations, with estimation of their ecological risks in the Sabarmati River, Gujarat, India<strong>.</strong> A total of 168 samples were collected from six sites, which were extracted using QuEChERS and analyzed via LC-MS/MS. The measured concentrations were 177 µg/L at Narmada Canal (NC), 165.72 µg/L at Indira Gandhi Bridge (IB), 155 µg/L at Middle Town Riverfront (MTRF), 145.2 µg/L at Riverfront Flower Park (RFFP), 187.6 µg/L at Vasna Barrage (VB), and 162 µg/L at the Wastewater Effluent site (WWE). The highest contamination was observed at VB, followed by NC & IB. Monthly variation data showed that azithromycin concentration was highest in August, while May and June recorded the lowest concentrations. Moreover, concentrations of azithromycin were observed to vary seasonally, with the highest levels during the monsoon, followed by the post-monsoon period, and the lowest during the pre-monsoon period. Further, a Risk Quotient (RQ) assessment identified algae as the most vulnerable organisms, while <em>Daphnia magna</em> and fish showed minimal risk. The contamination of azithromycin in the Sabarmati River might be due to pharmaceutical industries, human disposal activities, including other anthropogenic factors. The present findings underscore the need for urgent regulatory measures to monitor and mitigate antibiotic pollution.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"7 ","pages":"Article 100106"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Karthik, Arunachalam Thirunavukkarasu, Rajarathinam Nithya, Pillaikani Janani, Johnson Arputharaj Evelin, Sivakumar Bhuvaneshwari, Mary Leon Amshina Teresa
{"title":"Adsorptive removal of antibiotics from wastewater: A critical review of challenges and research gaps","authors":"V. Karthik, Arunachalam Thirunavukkarasu, Rajarathinam Nithya, Pillaikani Janani, Johnson Arputharaj Evelin, Sivakumar Bhuvaneshwari, Mary Leon Amshina Teresa","doi":"10.1016/j.scowo.2025.100107","DOIUrl":"10.1016/j.scowo.2025.100107","url":null,"abstract":"<div><div>The prevalent use of antibiotics in the varied sectors, including pharmaceutical industries, hospitals, and poultry/animal farms, is a primary source of antibiotic contamination in the freshwater system. Overdosing, improper handling, and disposal of antibiotics result in significant health effects on microbial communities, aquatic ecosystems, animals and humans. Several innovative strategies involving physical, chemical, and biological methods are being developed to remove antibiotics from polluted system with high efficiency. Of them, physical treatment techniques offer various advantages including ease of operation, versatile, flexible operations, eco-friendly and economically feasible. Surface adsorption science is the core concept behind most physical methods, exploting adsorbate-adsorbent interactions at solid-liquid interfaces for the batch process optimization. The scale-up of such adsorption process and their operation in continuous mode still require extensive research. Despite, the promising advantages of physical treatment methods, several bottlenecks hinder their effective implementation and commercialization such as high costs, regeneration challenges or low selectivity. Hence, this review is critically analyzes the key challenges and research gaps that need addressing by the scientific community.</div></div>","PeriodicalId":101197,"journal":{"name":"Sustainable Chemistry One World","volume":"8 ","pages":"Article 100107"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}