Supramolecular Materials最新文献_第8页

Progress for the development of antibacterial surface based on surface modification technology 基于表面改性技术的抗菌表面研究进展

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100008

Lin Huang , Chuan-Jun Liu

{"title":"Progress for the development of antibacterial surface based on surface modification technology","authors":"Lin Huang , Chuan-Jun Liu","doi":"10.1016/j.supmat.2022.100008","DOIUrl":"10.1016/j.supmat.2022.100008","url":null,"abstract":"<div><p>With the increasing requirement for antibacterial surface especially in biomedical apparatus, constructing the new material surface with bactericidal activity for combating the infection caused by multi-resistant microbials possesses great significance. The surface sterilization in traditional way cannot remove the bacteria completely, and new strategy which could kill the bacteria with high efficiency, safety and convenience is urgently needed. In this review, we recapitulate the commonly used approaches about surface modification technology for combating the bacteria on material surface. According to different mechanism of disinfectant, we first list two widely used bactericidal manners on surface, contacting killing and releasing killing, and summarize its characterizations. Then, the antibacterial surface with these killing factors are concluded, and further categorized into the form of covalent polymer brushes coatings and non-covalent supramolecular coatings. Besides, smart responsive surface adjusted by light, pH or salt, and surface morphology structure such as physical puncture are superficially discussed. We hope this review can provide a comprehensive knowledge in preparing for antibacterial surface.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100008"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000022/pdfft?md5=fc0c8ea4f2dd43b8a614b07fbd82cf51&pid=1-s2.0-S2667240522000022-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88662916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Converting microscale linear to rotary motion in kinesin-powered systems 在运动动力系统中将微尺度线性运动转换为旋转运动

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100022

Yifei Zhang , Henry Hess

引用次数: 1

Coupling an artificial receptor with macrophage membrane for targeted and synergistic treatment of cholestasis 巨噬细胞膜偶联人工受体靶向和协同治疗胆汁淤积症

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100020

Qiaoxian Huang , Zong-Ying Hu , Shuwen Guo , Dong-Sheng Guo , Ruibing Wang

{"title":"Coupling an artificial receptor with macrophage membrane for targeted and synergistic treatment of cholestasis","authors":"Qiaoxian Huang , Zong-Ying Hu , Shuwen Guo , Dong-Sheng Guo , Ruibing Wang","doi":"10.1016/j.supmat.2022.100020","DOIUrl":"https://doi.org/10.1016/j.supmat.2022.100020","url":null,"abstract":"<div><p>Cholestasis is defined as an impairment of bile acid flow leading to intrahepatic retention of toxic bile acids (BAs), which induce apoptosis or necrosis of hepatocytes and liver inflammation. Ursodeoxycholic acid (UDCA), a FDA-approved drug to treat cholestasis, has limited therapeutic effects due to its poor specificity. Herein, we report a targeted therapeutic platform (namely, MAP) based upon co-assembly of macrophage membrane and amphiphilic calix[4]arene on PLGA nanoparticles. With UDCA loaded into calix[4]arene on the surface, MAP exhibited long-term stability, excellent biocompatibility, prolonged retention in the inflammatory liver due to the homing effects of macrophage membrane, and effective therapy of cholestasis via the specific action of UDCA and efficient sequestration of toxic BAs and inflammatory cytokines by the artificial receptor and membrane receptors, respectively. This study not only provides an artificial receptor coupled macrophage-mimetic nanomedicine platform to conquer cholestasis but also offers new insights into the design of improved versions of biomimetic nanomaterials that harness the power of both the natural and artificial receptors.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100020"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000137/pdfft?md5=da3a127feffbb44045e9d5d520988faf&pid=1-s2.0-S2667240522000137-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136553696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discrete terpyridine-lanthanide molecular and supramolecular complexes 离散的三吡啶-镧系分子和超分子复合物

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100017

Xiujun Yu , Yaqi Hu , Chenxing Guo , Zhi Chen , Heng Wang , Xiaopeng Li

{"title":"Discrete terpyridine-lanthanide molecular and supramolecular complexes","authors":"Xiujun Yu , Yaqi Hu , Chenxing Guo , Zhi Chen , Heng Wang , Xiaopeng Li","doi":"10.1016/j.supmat.2022.100017","DOIUrl":"10.1016/j.supmat.2022.100017","url":null,"abstract":"<div><p>Integrating the advantages of terpyridine (tpy) ligands with excellent chromophoric sensitization ability and lanthanides (Lns) with characteristic luminescent and magnetic properties, discrete terpyridine-lanthanide (tpy-Ln) molecular and supramolecular complexes are of great value in many fields and have drawn significant attention from the community of supramolecular chemistry, coordination chemistry and materials science. Compared to the well-documented coordination behavior between transition metals and tpy, the construction of tpy-Ln molecular and supramolecular complexes remains a longstanding challenge due to the high coordination diversity and the lack of stereochemical preference of Lns. Nevertheless, with the advancement of self-assembly strategies, <em>i.e.</em>, employing diverse anions as capping components and utilizing secondary auxiliary ligands as well as engineering of tpy ligands, diverse tpy-Ln molecular and supramolecular complexes have been constructed and their potential applications have been explored. This review comprehensively summarizes the progress of discrete tpy-Ln molecular and supramolecular complexes in the past decades, covering the structures of mononuclear, binuclear and multinuclear architectures. Beyond structures, the potential applications of these tpy-Ln complexes are also introduced. This review aims to shed more light on the design and construction of novel discrete tpy-Ln supramolecular complexes and materials with molecular level precision and multiple functions through coordination-driven self-assembly.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100017"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000101/pdfft?md5=812ed8891e1ef6137276e6df197e36b4&pid=1-s2.0-S2667240522000101-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75497601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Visualizing polymer diffusion in hydrogel self-healing 可视化聚合物在水凝胶自愈中的扩散

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100009

Mengfan Hai , Qian Zhang , Zengzhao Li , Mengjiao Cheng , Alexander J.C. Kuehne , Feng Shi

{"title":"Visualizing polymer diffusion in hydrogel self-healing","authors":"Mengfan Hai , Qian Zhang , Zengzhao Li , Mengjiao Cheng , Alexander J.C. Kuehne , Feng Shi","doi":"10.1016/j.supmat.2022.100009","DOIUrl":"10.1016/j.supmat.2022.100009","url":null,"abstract":"<div><p>Self-healing hydrogels are attractive to extend material lifetime by rapid recovery from damage; the underlying healing mechanism regarding polymer diffusion are of broad research interest. However, intuitive and convenient characterization of polymer diffusion remains challenging due to the complex and dynamic features of hydrogels. Herein, we have constructed a dually-crosslinked hydrogel system to decouple complex factors for direct visualization of polymer diffusion and quantified study of healing dynamics. The successively formed dually-crosslinked hydrogel networks are designated for purposes of self-healing/visualization and tunable constraining effects (varied crosslinking density), respectively. As a result, we observed direct polymer diffusion across the crack interface and calculated the diffusion speed ranging from 0.51 to 0.04 μm/s depending on varied constraining degree. The corresponding self-healing performance is consistent with other conventional characterizations (e.g., dynamic mechanical properties, surface morphology changes). The above method has enabled facile visualization of dynamic healing processes with flexible adjustment of polymeric systems, which could inspire novel designs of high-performance self-healing materials.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100009"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000034/pdfft?md5=179aa73f04d696115bc0948da3b1cf2d&pid=1-s2.0-S2667240522000034-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83572830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Multicompartment polymer capsules 多室聚合物胶囊

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100015

Zhiliang Gao , Xiaomiao Cui , Jiwei Cui

引用次数: 2

Engineering coacervate droplets towards the building of multiplex biomimetic protocells 工程凝聚液滴构建多重仿生原细胞

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100019

Hua Wu , Yan Qiao

{"title":"Engineering coacervate droplets towards the building of multiplex biomimetic protocells","authors":"Hua Wu , Yan Qiao","doi":"10.1016/j.supmat.2022.100019","DOIUrl":"https://doi.org/10.1016/j.supmat.2022.100019","url":null,"abstract":"<div><p>The origin of life on Earth remains one of the biggest open questions in science. Despite recent advances in molecular mechanism of cell biology, a large blind spot still exists between non-living matter and the emergence of life which cannot be filled by biology alone. The quest to comprehend the cell origin inspires the construction of synthetic analogs (protocells) to mimic their life-like functionality and structural complexity. Among all kinds, coacervates formed by liquid-liquid phase separation featured by their dynamic structure, molecularly crowded interior and molecular sequestration capability, have been regarded as a protocell model for exploring the origin of life. Their biological counterparts in natural cells are also found to facilitate subcellular organization and spatiotemporal regulation of biological molecules. In this tutorial review, we summarize the recent progress on engineering coacervate protocells to potentially reproduce the function and structure of primitive life by multiphase organization, membranization and structural hybridization. Routes to high-ordered protocellular system comprising spatially arranged coacervates, as well as to the construction of tissue-like structures are also described. Finally, we deduce some perspectives of coacervate engineering in the direction of the emergence of life, from molecular scale to the emergence of integrated multicellular system.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100019"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000125/pdfft?md5=900a8735b5af9a45e2c13e35e9e59f82&pid=1-s2.0-S2667240522000125-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72280167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Self-assembly of fibril-forming histidine-rich peptides for cofactor-free oxidase-mimetic catalysis 用于无辅助因子氧化酶模拟催化的富含组氨酸的纤维形成多肽的自组装

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100012

Yuanxi Liu , Peidong Du , Qiao Teng , Hao Sun , XiangYu Ye , Zhen-Gang Wang

{"title":"Self-assembly of fibril-forming histidine-rich peptides for cofactor-free oxidase-mimetic catalysis","authors":"Yuanxi Liu , Peidong Du , Qiao Teng , Hao Sun , XiangYu Ye , Zhen-Gang Wang","doi":"10.1016/j.supmat.2022.100012","DOIUrl":"10.1016/j.supmat.2022.100012","url":null,"abstract":"<div><p>Most oxidases rely on the cofactors for catalyzing the electron transfer reactions, while tend to suffer from externally-induced protein unfolding, cofactor dissociation and nonrecovery of the activities. We have previously demonstrated that the self-assembled oligohistidine peptides, without assistance of the heme cofactor, can mimic the catalytic function of the heme-dependent peroxidases that promoted H<sub>2</sub>O<sub>2</sub> reduction reactions. Herein, we conjugate a fibril-forming peptide to the oligohistidine, to guide the self-assembly of the heme-free catalyst into amyloid-like structures, which facilitate the association of the histidine residues. The modified oligohistidine materials are able to catalyze H<sub>2</sub>O<sub>2</sub> reduction reactions efficiently through the formation of reactive ternary complex intermediates, similar to the mechanism to the unmodified oligohistdine, but the catalytic efficiency is over one order of magnitude higher. Moreover, the catalyst can be switched between inactive and active state without loss of activity for more than ten cycles of heating/cooling treatments, and showed selective oxidation of benzidine substrates over phenolic substrates. These results may aid the future design of the robust cofactor-free supramolecular catalysts and support the evolutionary link between the primitive amyloids and modern-day enzymes.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100012"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000058/pdfft?md5=c9322c4bba9a0d4b8dd4bac06f650569&pid=1-s2.0-S2667240522000058-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79742597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Stimuli-responsive hydrogel sponge for ultrafast responsive actuator 用于超快速响应驱动器的刺激响应水凝胶海绵

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2021.100002

Yukun Jian , Baoyi Wu , Xuxu Yang , Yu Peng , Dachuan Zhang , Yang Yang , Huiyu Qiu , Huanhuan Lu , Jiawei Zhang , Tao Chen

{"title":"Stimuli-responsive hydrogel sponge for ultrafast responsive actuator","authors":"Yukun Jian , Baoyi Wu , Xuxu Yang , Yu Peng , Dachuan Zhang , Yang Yang , Huiyu Qiu , Huanhuan Lu , Jiawei Zhang , Tao Chen","doi":"10.1016/j.supmat.2021.100002","DOIUrl":"10.1016/j.supmat.2021.100002","url":null,"abstract":"<div><p>With the ability to deform in response to specific stimuli, polymeric hydrogel actuators are important bionic materials. However, because shape deformation is derived from the diffusion of water molecules, the response rate of hydrogel actuators is usually slow, which severely limits their potential applications. In this work, a thermo-responsive PNIPAm hydrogel sponge is developed, and the hydrogel sponge shows ultrafast de-swelling/swelling capacity (equilibrium time 7 s) and large deformation degree (40%) due to the assistance of capillary force. Hydrogel sponge actuator with rapid response performance is further constructed, and the hydrogel sponge actuator could be used to capture moving objects and living creatures. Moreover, light-controlled directional movement can be achieved by incorporating photothermal functional components into the hydrogel sponge actuator. This work would promote the application of hydrogel actuators in soft robots.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100002"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240521000027/pdfft?md5=2740fa7c5da8f7236805e676d7169404&pid=1-s2.0-S2667240521000027-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79079997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Supramolecular microgels/microgel scaffolds for tissue repair and regeneration 用于组织修复和再生的超分子微凝胶/微凝胶支架

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2021.100006

Kai Wang, Zhaoyi Wang, Haijun Hu, Changyou Gao

{"title":"Supramolecular microgels/microgel scaffolds for tissue repair and regeneration","authors":"Kai Wang, Zhaoyi Wang, Haijun Hu, Changyou Gao","doi":"10.1016/j.supmat.2021.100006","DOIUrl":"10.1016/j.supmat.2021.100006","url":null,"abstract":"<div><p>Biomedical microgels are a novel type of materials with promising perspectives for repair and regeneration of multi-types of tissues and organs due to their highly hydrated nature, tunable microporous structure, ability to encapsulate bioactive factors, and tailorable properties such as stiffness and composition. In particular, the reversible bonding in supramolecular microgels leads to their ease of injectability and self-healing ability, which are essential for therapeutic delivery of cells and drugs, assembly to generate scaffolds, and bioinks for 3D printing. <em>In vivo</em> studies of microgels have pioneered the clinical relevance of these novel and innovative materials for regenerative medicine. In this review, the important supramolecular interactions such as hydrogen bonding, ionic bonding, and host-guest and hydrophobic interactions, and metal coordination are summarized with respect to the formation of supramolecular microgels for biomedical applications, highlighting their advantages over the traditional bulk ones. The applications of supramolecular microgels in the fields of cardiac tissue repair, osteoarthritis therapy, and bone and neuronal tissue engineering are discussed.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100006"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240521000064/pdfft?md5=6173a8fc8e74a873a7ddfeed58000f18&pid=1-s2.0-S2667240521000064-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91499568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11