Supramolecular Materials最新文献_第7页

Self-powered assemblies for tissue engineering applications 组织工程应用的自供电组件

Supramolecular Materials Pub Date : 2023-08-03 DOI: 10.1016/j.supmat.2023.100036

Yi Zhang , Qi An

{"title":"Self-powered assemblies for tissue engineering applications","authors":"Yi Zhang , Qi An","doi":"10.1016/j.supmat.2023.100036","DOIUrl":"https://doi.org/10.1016/j.supmat.2023.100036","url":null,"abstract":"<div><p>Bioelectric phenomena play important roles in living organisms and are essential for regulating cellular and tissue behavior. Electroactive assemblies can facilitate tissue repair and/or regulate neural activity by simulating the tissue microenvironment, while providing electrical signals and biocompatible component niches. Self-powered nanogenerators including TENG and PENG are essential part in electroactive assemblies. Assemblies incorporating TENG or PENG can present the advantages of controllable morphology, portability, low cost, and flexibility, making them a new and promising research content in the biomedical field. Herein, we describe in detail the basic physical rules underlining electric field generations in assemblies, and discuss constructing rules and research progress of self-powered assemblies in tissue engineering. Their applications in the fields of bone tissue repair and regeneration, nerve modulation and injury repair, skin wound healing, and antibacterial are sequentially discussed. Finally, current challenges and possible solutions of self-powered artificial assemblies are discussed, expecting to promote the research efforts and advance the self-powered assemblies from laboratory to clinical applications.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"2 ","pages":"Article 100036"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49738993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrazide–pillar[5]arene-mediated silver nanoparticles for highly efficient reductive degradation of organic dyes 用于高效还原降解有机染料的酰腙柱[5]芳烃介导的纳米银

Supramolecular Materials Pub Date : 2023-06-10 DOI: 10.1016/j.supmat.2023.100035

Chun-Li Song, Zheng Li, Yi-Nan Zhang, Ge Zhang, Ying-Wei Yang

引用次数: 3

Block copolymer particles with tunable and robust internal nanostructures by combining hydrogen-bonding and crosslinking 通过结合氢键和交联，嵌段共聚物颗粒具有可调和坚固的内部纳米结构

Supramolecular Materials Pub Date : 2023-05-11 DOI: 10.1016/j.supmat.2023.100034

Shuai Deng , Tinghao Yan , Mian Wang , Jingye Liu , Renhua Deng , Jintao Zhu

{"title":"Block copolymer particles with tunable and robust internal nanostructures by combining hydrogen-bonding and crosslinking","authors":"Shuai Deng , Tinghao Yan , Mian Wang , Jingye Liu , Renhua Deng , Jintao Zhu","doi":"10.1016/j.supmat.2023.100034","DOIUrl":"https://doi.org/10.1016/j.supmat.2023.100034","url":null,"abstract":"<div><p>Nanostructured block copolymer (BCP) particles are attractive due to their ordered internal structures, unique shape and surface patterns; however, their structural integrity can be easily lost because of weak intermolecular interactions, which limits their practical applications. In this study, we present a simple and reliable method to fabricate nanostructured particles of polystyrene-<em>block</em>-poly(4-vinylpyridine) with tunable and robust nanostructures by employing hydrogen-bonding and cross-linking strategies. The key feature of poly(4-vinylpyridine) is the presence of reactive pyridyl moieties, which allow precise regulation of internal nanostructures via hydrogen bonds and locking of the structural integrity via quaternarization by feeding hydrogen bond donors and cross-linkers, respectively. The solvent resistance is well proven by immersing the particles in either selective solvents of the continuous phase or good solvent of the BCP. Furthermore, mesoporous BCP particles derived from the cross-linked particles are obtained simply by a swelling/deswelling treatment. This study provides a way to improve the structural robustness of BCP particles and could be a key step that advances the functionalization and subsequent applications of such nanostructured BCP colloidal particles<em>.</em></p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"2 ","pages":"Article 100034"},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49719420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In situ supramolecular self-assembly for alleviating multidrug resistance in cancer 原位超分子自组装减轻癌症多药耐药

Supramolecular Materials Pub Date : 2023-04-26 DOI: 10.1016/j.supmat.2023.100033

Jie Zhao , Xiaobo Wu , Jiali Chen , Chengling Wu , Ruijia Zhang , Qingxin Yao , Jianjun Xie , Yuan Gao

{"title":"In situ supramolecular self-assembly for alleviating multidrug resistance in cancer","authors":"Jie Zhao , Xiaobo Wu , Jiali Chen , Chengling Wu , Ruijia Zhang , Qingxin Yao , Jianjun Xie , Yuan Gao","doi":"10.1016/j.supmat.2023.100033","DOIUrl":"https://doi.org/10.1016/j.supmat.2023.100033","url":null,"abstract":"<div><p>Drug resistance is one of the major causes of cancer treatment failures. In recent years, to combat the issue of drug resistance, a large volume of strategies has been established along the development of biomedical nanomaterials. Compared with traditional nanocarrier-based drug delivery strategies, <em>in situ</em> supramolecular self-assembly has emerged as a promising strategy to overcome drug resistance. This review first introduced the concept of <em>in situ</em> supramolecular self-assembly. The second part illustrated the mechanisms of constructing <em>in situ</em> supramolecular self-assembly as a multi-step process. The third part elucidated the role of <em>in situ</em> supramolecular self-assembly to reverse drug resistance, which included three categories: active self-assembly materials, drug-carrier self-assembly materials and drug-coupled self-assembly materials. At last, we summarized the current development of <em>in situ</em> supramolecular self-assembly for the reversal of drug resistance and the remaining concerns to be addressed.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"2 ","pages":"Article 100033"},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49738989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogen-bonded supramolecular adhesives: Synthesis, responsiveness, and application 氢键超分子胶粘剂:合成、反应性和应用

Supramolecular Materials Pub Date : 2023-02-10 DOI: 10.1016/j.supmat.2023.100032

Senbin Chen, Kaixing Zhang, Zeke Li, Yanggui Wu, Bengao Zhu, Jintao Zhu

{"title":"Hydrogen-bonded supramolecular adhesives: Synthesis, responsiveness, and application","authors":"Senbin Chen, Kaixing Zhang, Zeke Li, Yanggui Wu, Bengao Zhu, Jintao Zhu","doi":"10.1016/j.supmat.2023.100032","DOIUrl":"https://doi.org/10.1016/j.supmat.2023.100032","url":null,"abstract":"<div><p>Adhesive bonding to diverse substances is vital to a great number of the established, cutting-edge and emerging applications. We have witnessed, in the last few years, the transformative progress in achieving robust adhesive bonding and tunable debonding behavior, which mostly employing the supramolecular forces. Among the diverse supramolecular forces, the contribution of hydrogen-bonds (H-bonds) to adhesives, on the modality of directionality, selectivity and sensitivity, can function as nano-scaled bonding agents for improved interfacial interactions, thus paved novel perspectives to the design and creation of glue materials with outstanding performance. On account of the dynamic and reversible feature, a characteristic principally determined for H-bonding (macro)molecules could be employed as adhesive platform for affording outstanding attaching, connecting and on demand disconnecting, arising from the combination of adhesion/cohesion process via H-bonding interactions and the responsive characteristics. Thus, H-bonded adhesives with abundant diverse molecular configuration furnish a rich toolbox that can fulfill universal yet specific needs with unique advantages, demonstrating great opportunities for fundamental researches and practical applications. Herein we outline and summarize the design and creation of H-bonded adhesives, responsive attaching/detaching, and applications in advanced materials. We propose the guidance for further designing H-bonded adhesives, in concert with biomedical science, physics, mechanical and electric, informatics or robotics of promising future.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"2 ","pages":"Article 100032"},"PeriodicalIF":0.0,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49719183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Perylene diimide supramolecular aggregates: Constructions and sensing applications 苝二亚胺超分子聚集体:结构和传感应用

Supramolecular Materials Pub Date : 2023-02-07 DOI: 10.1016/j.supmat.2023.100031

Junhong Wu, Min Peng, Mengxin Mu, Jie Li, Meizhen Yin

引用次数: 5

Exploring chemical space and structural diversity of supramolecular peptide materials 探索超分子多肽材料的化学空间和结构多样性

Supramolecular Materials Pub Date : 2022-12-31 DOI: 10.1016/j.supmat.2022.100030

Mengyue Zhu, Jing Chen, Yiyang Lin

引用次数: 0

Multicomponent coassembled nanodrugs based on ovalbumin, pheophorbide a and Zn2+ for in vitro photodynamic therapy 体外光动力治疗中基于卵清蛋白、磷酸a和Zn2+的多组分协同组装纳米药物

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100010

Xiaoyan Ma , Yamei Liu , Shukun Li , Kenji Ogino , Ruirui Xing , Xuehai Yan

{"title":"Multicomponent coassembled nanodrugs based on ovalbumin, pheophorbide a and Zn2+ for in vitro photodynamic therapy","authors":"Xiaoyan Ma , Yamei Liu , Shukun Li , Kenji Ogino , Ruirui Xing , Xuehai Yan","doi":"10.1016/j.supmat.2022.100010","DOIUrl":"10.1016/j.supmat.2022.100010","url":null,"abstract":"<div><p>Photodynamic therapy (PDT) has been considered as a therapeutic method based on non-invasiveness and lower side effect. However, photosensitizers (PS), as a major component of PDT, suffer from aggregation and limit reactive oxygen species (ROS) generation in the delivery process, thus causing unsatisfactory therapeutic effect of PDT. Herein, we demonstrate a multicomponent coordination coassembly strategy based on the combination of metal-binding protein (ovalbumin, OVA), metal ions (Zn<sup>2+</sup>) and a photosensitive drug (pheophorbide a, PheoA) for constructing supramolecular photosensitive nanodrugs towards antitumor PDT. The resulting photosensitizer nanodrugs exhibit well-defined nanorod structures, good colloidal dispersity, and high encapsulation efficiency. Most importantly, multicomponent coassembled nanorods possess favorable stability of physiological environment and on-demand release of PS in response to an acidic ambient in tumor cells. These features result in the high level of ROS generation in tumor cells, benefiting for enhanced therapeutic effect of <em>in vitro</em> PDT.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100010"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000046/pdfft?md5=cd59a157b7ae9dcc0f59fc08e31f204f&pid=1-s2.0-S2667240522000046-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73316717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Metallacycle-crosslinked supramolecular polymers constructed by amino–YNE click reaction with enhanced mechanical properties 由氨基-炔键合反应构建的具有增强力学性能的金属环交联超分子聚合物

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2021.100003

Feng Chen, Xiongjie Lin, Yang Li, Dongdong Xu, Huayu Qiu, Shouchun Yin

引用次数: 10

Light controlled drug-based supramolecular polymer self-assemblies for efficient antibacterial manipulation 用于高效抗菌操作的光控药物基超分子聚合物自组装

Supramolecular Materials Pub Date : 2022-12-01 DOI: 10.1016/j.supmat.2022.100014

Chengfei Liu , Zuoting Yang , Xin Song, Yongchao Qian, Hongbin Huo, Jia He, JuAn Zhang, Zhelin Zhang, Menghan Shi, Jun Pang, Baoliang Zhang, Wei Tian

{"title":"Light controlled drug-based supramolecular polymer self-assemblies for efficient antibacterial manipulation","authors":"Chengfei Liu , Zuoting Yang , Xin Song, Yongchao Qian, Hongbin Huo, Jia He, JuAn Zhang, Zhelin Zhang, Menghan Shi, Jun Pang, Baoliang Zhang, Wei Tian","doi":"10.1016/j.supmat.2022.100014","DOIUrl":"https://doi.org/10.1016/j.supmat.2022.100014","url":null,"abstract":"<div><p>The infections and diseases caused by harmful bacteria are regarded as the worldwide health-threatening issue. The most antibiotics-based delivery systems restricted the controlled drug release at specific infection sites due to the stable chemical conjugation, thus largely compromising the treatment effectiveness. Herein, we report the construction of light controlled drug-based supramolecular polymer (<strong>LDSP</strong>), which is endowed the “switch on” function for realizing the controllable antibiotics released in specific sites. <strong>LDSP</strong> was first formed based on the host-guest interaction between β-cyclodextrin units grafted hyaluronic acid chain (<strong>HA-CD</strong>) and azobenzene moiety linked by two enoxacin units (<strong>Azo-(Eno)<sub>2</sub></strong>), and could further self-assemble into light controlled drug-based supramolecular polymer self-assemblies (<strong>LDSPSAs</strong>). Under the UV light irradiation, the “switch on” function of <strong>LDSPSAs</strong> could be effectively turned on at the specific infected tissues due to the smartly dissociated host-guest interaction, facilitating the controlled release of the hydrophobic <strong>Azo-(Eno)<sub>2</sub></strong> to interact with bacteria for efficient antibacterial effect. The biological evaluation demonstrated that <strong>LDSPSAs</strong> achieved good antibacterial efficiency and well biosafety.</p></div>","PeriodicalId":101187,"journal":{"name":"Supramolecular Materials","volume":"1 ","pages":"Article 100014"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667240522000071/pdfft?md5=b28bb8198cf0ae34df00d53b414600e3&pid=1-s2.0-S2667240522000071-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136553695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0