Spanish Journal of Psychiatry and Mental Health最新文献

{"title":"Psychotherapies in current clinical psychology and psychiatry in Spain","authors":"José Manuel Bertolín Guillén","doi":"10.1016/j.rpsm.2020.01.004","DOIUrl":"10.1016/j.rpsm.2020.01.004","url":null,"abstract":"<div><h3>Background</h3><p>The practice of psychotherapy in Spain (Europe) continues being a reason for doubts, uncertainty, controversy or confusion. The access to psychotherapy is also controversial. To contribute to clarify all this in order to improve quality and minimise risks is the aim of our work.</p></div><div><h3>Method</h3><p>Update of the regulations and legal rules which are applicable in psychotherapy to those graduated in both psychology and medicine.</p></div><div><h3>Results and discussion</h3><p>Neuroscience, clinical psychology and psychiatry<span> develop in a parallel and convergent way. It is necessary to emphasise the risks of pseudotherapies, including pseudopsychotherapies, and pseudosciences in general. The practice of psychotherapy as a psychological treatment necessarily implies the healthcare field both for the private and public sectors. In order to practice as a psychotherapist in Spain, it is necessary to be a psychologist specialised in clinical psychology or a doctor specialised in psychiatry. The figure of the sanitary general psychologist is a regulated profession in Spain at present, but that is not equivalent to be a specialist. The former psychologists who have the required legal qualification are also allowed to act for the public sector in the healthcare field. Other doctors who are not psychiatrists, other psychologists or the nurses specialised in mental health are not allowed to name themselves or act as psychotherapists in any field or sector.</span></p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 59-63"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37877668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Humanization in mental health plans in Spain","authors":"David Fraguas ,&nbsp;Julio Zarco ,&nbsp;Vicent Balanzá-Martínez ,&nbsp;Juan Francisco Blázquez García ,&nbsp;Cecilia Borràs Murcia ,&nbsp;Ana Cabrera ,&nbsp;Julián Carretero ,&nbsp;Agustina Crespo ,&nbsp;Marina Díaz-Marsá ,&nbsp;Vicente Gasul ,&nbsp;Miguel A. González ,&nbsp;Iria Grande ,&nbsp;Carmen Muela ,&nbsp;Elena de las Heras Liñero ,&nbsp;Fermín Mayoral ,&nbsp;Guadalupe Morales Cano ,&nbsp;José Ramón Pagés-Lluyot ,&nbsp;José Romo ,&nbsp;Bibiana Serrano Marín ,&nbsp;Antonio Lozano Sauceda ,&nbsp;Celso Arango","doi":"10.1016/j.rpsm.2021.08.003","DOIUrl":"10.1016/j.rpsm.2021.08.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Mental health (MH) care has important challenges, especially in the field of humanization. Our objectives were to identify the humanization measures in MH plans of the Spanish autonomous communities (AC) and the priorities to be developed in this area.</p></div><div><h3>Material and methods</h3><p>A large and multidisciplinary group of people involved in MH care participated in a consensus, according to a modified Delphi method, based on «design thinking», in three phases: (1) identification of humanization measures in MH plans of AC; (2) analysis of the implementation of these measures; and (3) identification of humanization priorities in MH.</p></div><div><h3>Results</h3><p>Fourteen of the 17 AC have current MH plans. They contained four types of humanization measures: (1) improvement of the quality of care; (2) promotion of user participation; (3) campaigns against stigma and discrimination; (4) caring for especially vulnerable people. Implementation of measures ranged from 6.3% (i.e.: specific budget) to 100%, with an average of 64.1%. We identified priority issues, operationalized in 5 proposals: (1) information campaigns; (2) multidisciplinary meeting forums; (3) platforms of support entities; (4) strategies on MH education; (5) humanization in study plans.</p></div><div><h3>Conclusions</h3><p>Some MH plans include humanization among their objectives, but partially. The implementation of humanization proposals such as those identified in this study is essential to achieve a high-quality MH care.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 71-80"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39392799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Content validation using Aiken methodology through expert judgment of the first Spanish version of the Eppendorf Schizophrenia Inventory (ESI) in Peru: A brief qualitative report","authors":"Victor Anculle-Arauco ,&nbsp;Hever Krüger-Malpartida ,&nbsp;Martin Arevalo-Flores ,&nbsp;Liany Correa-Cedeño ,&nbsp;Reinhard Mass ,&nbsp;Wolfgang Hoppe ,&nbsp;Bruno Pedraz-Petrozzi","doi":"10.1016/j.rpsm.2022.11.004","DOIUrl":"10.1016/j.rpsm.2022.11.004","url":null,"abstract":"<div><h3>Background</h3><p>The main objective of this study was the validation through the expert judgment of the first Spanish version of the Eppendorf Schizophrenia Inventory (ESI-Sp).</p></div><div><h3>Materials and methods</h3><p>A translation and cultural adaptation procedure as a first stage was carried out, which was evaluated by four psychiatrists with clinical experience. In a second stage, we recruited a group of clinical psychiatrists to evaluate the translated instrument by judging the items’ clarity and relevance. Content validity was performed using the Aiken methodology (Aiken's <em>V</em>).</p></div><div><h3>Results</h3><p>For the first stage, we did not find any items that needed alteration during translation and adaptation. Concerning the raters’ stage, 30 clinical psychiatrists (47.07<!--> <!-->±<!--> <!-->13.62 years) completed the rating of the ESI-Sp. Of them, the majority worked in an institute (10/30; 33.33%) and had “15 or more” years of experience (12/30; 40.00%). The null hypothesis was rejected for all items and demonstrated the content validity of each item. Similar results were found for the factors of the ESI. Finally, the total Aiken's <em>V</em> for the ESI did not include the values of the null hypothesis in the confidence intervals (<em>V</em> <!-->=<!--> <!-->0.78; CI95 [0.70; 0.85]), demonstrating content validity.</p></div><div><h3>Conclusions</h3><p>ESI-Sp is a valid and representative instrument to determine subjective experiences in patients with a high risk of schizophrenia. The construct validation of the ESI-Sp is pending, which our research group will carry out after this first step.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 110-113"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41238293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basic quality indicators for clinical care of patients with major depression, schizophrenia, and bipolar disorder","authors":"Eduard Vieta ,&nbsp;José Manuel Menchón Magriña ,&nbsp;Miguel Bernardo Arroyo ,&nbsp;Víctor Pérez Sola ,&nbsp;Carmen Moreno Ruiz ,&nbsp;Celso Arango López ,&nbsp;Julio Bobes García ,&nbsp;Manuel Martín Carrasco ,&nbsp;Diego Palao Vidal ,&nbsp;Ana González-Pinto Arrillaga","doi":"10.1016/j.rpsm.2023.03.001","DOIUrl":"10.1016/j.rpsm.2023.03.001","url":null,"abstract":"<div><h3>Objective</h3><p><span>To identify a set of indicators to monitor the quality of care for patients with major depression, schizophrenia, or </span>bipolar disorder.</p></div><div><h3>Methods</h3><p>A group of 10 experts selected the most automatically applicable indicators from a total of 98 identified in a previous study. Five online sessions and 5 discussion meetings were performed to select the indicators that met theoretical feasibility criteria automatically. Subsequently, feasibility was tested in a pilot study conducted in two hospitals of the Spanish Health Service.</p></div><div><h3>Results</h3><p><span><span>After evaluating its measurement possibilities in the Spanish Health Service, and the fulfillment of all the quality premises defined, 16 indicators were selected. Three were indicators of major depression, 5 of schizophrenia, 3 of bipolar disorder, and 5 indicators common to all three pathologies. They included measures related to patient safety, maintenance and follow-up of </span>treatment, therapeutic adherence, and adequacy of hospital admissions. After the pilot study, 5 indicators demonstrated potential in the automatic generation of results, with 3 of them related to treatments (clozapine in schizophrenia, lithium for bipolar disorder, and </span>valproate in women of childbearing age).</p></div><div><h3>Conclusions</h3><p>Indicators support the monitoring of the quality of treatment of patients with major depression, schizophrenia, or bipolar disorder. Based on this proposal, each care setting can draw up a balanced scorecard adjusted to its priorities and care objectives, which will allow for comparison between centers.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 103-109"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49681817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of mental disorders in Mexico, 1990-2019: Mental and neurological disorders, substance use, suicides, and related somatic disorders","authors":"José Ángel García-Pacheco ,&nbsp;María de Lourdes Torres Ortega ,&nbsp;Guilherme Borges","doi":"10.1016/j.rpsm.2021.06.005","DOIUrl":"10.1016/j.rpsm.2021.06.005","url":null,"abstract":"<div><h3>Introduction</h3><p>Mental, neurological, substance use, suicide, and related somatic disorders<span> (MNSS, for the Spanish acronym) have a negative impact on the quality-of-life of people and the Mexican economy, but updated information is lacking. The objective of this work is to analyze the disability adjusted life years (DALYs) of the MNSS in Mexico by sex, age, state, and degree of marginalization between 1990 and 2019.</span></p></div><div><h3>Methods</h3><p>The data and methodology of the «Global Burden of Disease Group» (GBD) are used. The GBD calculates DALYs as the sum of two components: years of life lost due to premature mortality (YLL) and years lived with disability (YLD). Likewise, the data on the degree of marginalization from the National Population Council in Mexico are used.</p></div><div><h3>Results</h3><p>MNSS represented 16.3% of the disease burden in the Mexican population in 2019. The trend of the age-standardized rates of DALYs of the MNSS has increased little from 1990 to 2019. The highest increase has been for women. Mental (depression) and neurological (headache) disorders contribute the most to the disease burden among MNSS. In the interior of the country, Baja California Sur presented the highest increase in the period.</p></div><div><h3>Discussion</h3><p>The results show a complex panorama of the MNSS and its subtypes by sex, age groups and territory. More resources are needed to improve mental health care.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 64-70"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39172129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic and gender inequalities in mental disorders among adolescents and young adults","authors":"Javier Mar ,&nbsp;Igor Larrañaga ,&nbsp;Oliver Ibarrondo ,&nbsp;Ana González-Pinto ,&nbsp;Carlota las Hayas ,&nbsp;Ane Fullaondo ,&nbsp;Irantzu Izco-Basurko ,&nbsp;Jordi Alonso ,&nbsp;Maider Mateo-Abad ,&nbsp;Esteban de Manuel ,&nbsp;on behalf of the UPRIGHT Consortium","doi":"10.1016/j.rpsm.2022.07.001","DOIUrl":"10.1016/j.rpsm.2022.07.001","url":null,"abstract":"<div><h3>Background</h3><p>Socioeconomic status (SES) and gender play a key role in mental health. The objective of this study was to assess socioeconomic and gender mental health inequalities in adolescents and young adults using a population-based registry.</p></div><div><h3>Materials and methods</h3><p>We conducted a lifetime follow-up study of all residents in the Basque Country between 1 and 30 years old (<em>n</em> <!-->=<!--> <!-->609,381) as of 31 December 2018. Primary care, specialized outpatient, and hospital care records were searched for diagnoses. SES was assessed based on household income. We estimated disaggregated lifetime prevalence of substance use, behaviour, anxiety, depression, psychosis, and attention deficit hyperactivity disorder. The local Institute of Statistics validated the mortality data. The likelihood of risks was estimated using logistic regression.</p></div><div><h3>Results</h3><p>Overall, 96,671 individuals (15.9%) had a diagnosed mental disorder, with clear gradients by gender and SES. Females of medium-to-high SES had the lowest prevalence of all mental disorders, except anxiety and depression. This group was followed by males of the same SES and females of low SES, while the highest prevalence of mental disorders was observed in low-SES males. The lower income categories had higher risks of psychiatric admission (adjusted odds ratio [AOR]: 3.64 for females; 6.66 for males) and death (AOR: 5.42). People with a mental health diagnosis had higher mortality (AOR: 2.38).</p></div><div><h3>Conclusions</h3><p>Our work evidenced important SES and gender inequalities in the mental health and premature mortality of adolescents and young adults, findings that should drive the development and implementation of early preventive interventions.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 95-102"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989122000763/pdfft?md5=c9b5f5508d0ebb2f31f278e81a6d2d37&pid=1-s2.0-S1888989122000763-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89796902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upholding rights through fostering equity and quality in mental health care","authors":"Benedicto Crespo-Facorro","doi":"10.1016/j.sjpmh.2024.04.001","DOIUrl":"https://doi.org/10.1016/j.sjpmh.2024.04.001","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 57-58"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950285324000243/pdfft?md5=1f1aa1549d46cf052b399d0000f9bc17&pid=1-s2.0-S2950285324000243-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140843788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective connectivity of the locus coeruleus in patients with late-life Major Depressive Disorder or mild cognitive impairment.","authors":"Pablo Maturana-Quijada, Pamela Chavarría-Elizondo, Inés Del Cerro, Ignacio Martínez-Zalacaín, Asier Juaneda-Seguí, Andrés Guinea-Izquierdo, Jordi Gascón-Bayarri, Ramón Reñé, Mikel Urretavizcaya, José M Menchón, Isidre Ferrer, Virginia Soria, Carles Soriano-Mas","doi":"10.1016/j.sjpmh.2024.02.002","DOIUrl":"10.1016/j.sjpmh.2024.02.002","url":null,"abstract":"<p><strong>Introduction: </strong>We compared effective connectivity from the locus coeruleus (LC) during the resting-state in patients with late-life Major Depressive Disorder (MDD), individuals with amnestic Mild Cognitive Impairment (aMCI), and Healthy Controls (HCs).</p><p><strong>Participants: </strong>23 patients with late-life MDD, 22 patients with aMCI, and 28 HCs.</p><p><strong>Material and methods: </strong>Participants were assessed in two time-points, 2 years apart. They underwent a resting-state functional magnetic resonance imaging and a high-resolution anatomical acquisition, as well as clinical assessments. Functional imaging data were analyzed with dynamic causal modeling, and parametric empirical Bayes model was used to map effective connectivity between 7 distinct nodes: 4 from the locus coeruleus and 3 regions displaying gray matter decreases during the two-year follow-up period.</p><p><strong>Results: </strong>Longitudinal analysis of structural data identified three clusters of larger over-time gray matter volume reduction in patients (MDD+aMCI vs. HCs): the right precuneus, and the visual association and parahippocampal cortices. aMCI patients showed decreased effective connectivity from the left rostral to caudal portions of the LC, while connectivity from the left rostral LC to the parahippocampal cortex increased. In MDD, there was a decline in effective connectivity across LC caudal seeds, and increased connectivity from the left rostral to the left caudal LC seed over time. Connectivity alterations with cortical regions involved cross-hemisphere increases and same-hemisphere decreases.</p><p><strong>Conclusions: </strong>Our discoveries provide insight into the dynamic changes in effective connectivity in individuals with late-life MDD and aMCI, also shedding light on the mechanisms potentially contributing to the onset of neurodegenerative disorders.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term trajectories of clinical staging in first-episode psychosis and their associated cognitive outcome: A 21-year follow-up study.","authors":"Manuel J Cuesta, Ana M Sánchez-Torres, Lucia Moreno-Izco, Elena García de Jalón, Gustavo J Gil-Berrozpe, Victor Peralta, Alejandro Ballesteros, Lourdes Fañanás, Lucia Janda, Sergi Papiol, David Peralta, María Ribeiro, Ángela Rosero, Amalia Zarzuela, Eloi Giné, Esther Rosado","doi":"10.1016/j.sjpmh.2024.02.001","DOIUrl":"10.1016/j.sjpmh.2024.02.001","url":null,"abstract":"<p><p>Cognitive deficits are already present before psychosis onset but are a key feature of first-episode psychosis (FEP). The objective of this study was to investigate the cognitive outcomes of a cohort of FEP patients who were diagnosed using the clinical staging approach and were followed for up to 21 years. We analyzed data from 173 participants with first-admission psychosis who were followed-up for a mean of 20.9 years. The clinical staging assessment was adapted from the clinical staging framework developed by McGorry et al.¹ Cognitive assessment was performed using the MATRICS Consensus Cognitive Battery (MMCB) at the end of follow-up. FEP patients who were longitudinally diagnosed in the lowest clinical stages (stages 2A and 2B) showed better performance in attention, processing speed, and MCCB overall composite score than those in the highest clinical stages (stages 4A and 4B). There was a significant linear trend association between worsening of all MCCB cognitive functions and MCCB overall composite score and progression in clinical staging. Furthermore, the interval between two and five years of follow-up appears to be associated with deficits in processing speed as a cognitive marker. Our results support the validation of the clinical staging model over a long-term course of FEP based on neuropsychological performance. A decline in some cognitive functions, such as processing speed, may facilitate the transition of patients to an advanced stage during the critical period of first-episode psychosis.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in clinical response to deep brain stimulation in resistant obsessive-compulsive disorder.","authors":"Lorea Mar-Barrutia, Oliver Ibarrondo, Javier Mar, Eva Real, Cinto Segalàs, Sara Bertolín, Marco Alberto Aparicio, Gerard Plans, José Manuel Menchón, Pino Alonso","doi":"10.1016/j.sjpmh.2024.01.006","DOIUrl":"10.1016/j.sjpmh.2024.01.006","url":null,"abstract":"<p><strong>Introduction: </strong>Deep brain stimulation (DBS) is an effective alternative to treat severe refractory obsessive-compulsive disorder (OCD), although little is known on factors predicting response. The objective of this study was to explore potential sex differences in the pattern of response to DBS in OCD patients.</p><p><strong>Methods: </strong>We conducted a prospective observational study in 25 patients with severe resistant OCD. Response to treatment was defined as a ≥35% reduction in Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score. Logistic regression models were calculated to measure the likelihood of response at short and long-term follow-up by sex as measured by Y-BOCS score. Similar analyses were carried out to study changes in depressive symptomatology assessed with the Hamilton Depression Rating Scale (HDRS). Additionally, effect sizes were calculated to assess clinical significance.</p><p><strong>Results: </strong>We did not observe significant clinical differences between men and women prior to DBS implantation, nor in the response after one year of stimulation. At long-term follow-up, 76.9% of men could be considered responders to DBS versus only 33.3% of women. The final response odds ratio in men was 10.05 with significant confidence intervals (88.90-1.14). No other predictors of response were identified. The sex difference in Y-BOCS reduction was clinically significant, with an effect size of 3.2. The main limitation was the small sample size.</p><p><strong>Conclusions: </strong>Our results suggest that gender could influence the long-term response to DBS in OCD, a finding that needs to be confirmed in new studies given the paucity of results on predictors of response to DBS.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}