Spanish Journal of Psychiatry and Mental Health最新文献

{"title":"Correlation between low sleep satisfaction and death wish in a three-month Ecological Momentary Assessment study.","authors":"Francisco J Diaz, María L Barrigón, Ismael Conejero, Alejandro Porras-Segovia, Jorge Lopez-Castroman, Philippe Courtet, Jose de Leon, Enrique Baca-García","doi":"10.1016/j.sjpmh.2024.06.003","DOIUrl":"10.1016/j.sjpmh.2024.06.003","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141474391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking down processing speed: Motor and cognitive insights in first-episode psychosis and unaffected first-degree relatives.","authors":"Ángel Yorca-Ruiz, Rebeca Magdaleno Herrero, Víctor Ortiz García de la Foz, Nancy Murillo-García, Rosa Ayesa-Arriola","doi":"10.1016/j.sjpmh.2024.06.002","DOIUrl":"10.1016/j.sjpmh.2024.06.002","url":null,"abstract":"<p><strong>Introduction: </strong>Processing speed (PS) deficits represent a fundamental aspect of cognitive impairment, evident not only in schizophrenia but also in individuals undergoing their first episode of psychosis (FEP) and their unaffected first-degree relatives. Heterogeneity in tests assessing PS reflects the participation of motor and cognitive subcomponents to varying degrees. We aim to explore differences in performance of the subcomponents of PS in FEP patients, parents, siblings, and controls.</p><p><strong>Materials and methods: </strong>Results from tests, including Trail Making Test part A and part B, Digit Symbol Coding Test, Grooved Pegboard Test, and Stroop Word and Stroop Color subtests, were obtained from 133 FEP patients, 146 parents, and 202 controls. Exploratory factor analysis (EFA) was employed in controls to establish the structure, followed by confirmatory factor analysis (CFA) to verify if the other groups share this structure.</p><p><strong>Results: </strong>EFA revealed a two-factor model: Factor 1 for the motor subcomponent and Factor 2 for the cognitive subcomponent. Subsequently, CFA indicated a good fit for the remaining groups with differences in the relationship between the factors.</p><p><strong>Conclusions: </strong>Differences in the relationships of factors within a common structure suggest the involvement of different compensatory strategies among groups, providing insights into the underlying mechanisms of PS deficits in patients and relatives.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clozapine use in the first two years after first-episode psychosis in a real-world clinical sample.","authors":"Emilio Pechuán, Alba Toll, Daniel Bergé, Teresa Legido, Laura Martínez-Sadurní, Amira Trabsa, Gonzalo De Iturbe, Sara García Fernández, Beltran Jiménez-Fernández, Aurea Fernández, Víctor Pérez-Solà, Anna Mané","doi":"10.1016/j.sjpmh.2024.06.001","DOIUrl":"10.1016/j.sjpmh.2024.06.001","url":null,"abstract":"<p><strong>Background: </strong>Approximately 20-30% of patients with schizophrenia fail to respond to antipsychotic treatment and are considered treatment resistant (TR). Although clozapine is the treatment of choice in these patients, in real-world clinical settings, clinicians often delay clozapine initiation, especially in first-episode psychosis (FEP).</p><p><strong>Aim: </strong>The main aim of this study was to describe prescription patterns for clozapine in a sample of patients diagnosed with FEP and receiving specialized treatment at a university hospital. More specifically, we aimed to determine the following: (1) the proportion of patients who received clozapine within two years of disease onset, (2) baseline predictors of clozapine use, (3) time from starting the first antipsychotic to clozapine initiation, (4) concomitant medications, and (5) clozapine-related adverse effects.</p><p><strong>Methods: </strong>All patients admitted to a specialized FEP treatment unit at our hospital between April 2013 and July 2020 were included and followed for two years. The following variables were assessed: baseline sociodemographic characteristics; medications prescribed during follow-up; clozapine-related adverse effects; and baseline predictors of clozapine use. We classified the sample into three groups: clozapine users, clozapine-eligible, and non-treatment resistant (TR).</p><p><strong>Results: </strong>A total of 255 patients were consecutively included. Of these, 20 (7.8%) received clozapine, 57 (22.4%) were clozapine-eligible, and 178 (69.8%) were non-TR. The only significant variable associated with clozapine use at baseline was the Global Assessment of Functioning (GAF) score (R²=0.09, B=-0.07; OR=0.94; 95% CI: 0.88-0.99; p=0.019). The median time to clozapine initiation was 55.0 (93.3) days. The most common side effect was sedation.</p><p><strong>Conclusions: </strong>A significant proportion (30.2%) of patients in this cohort were treatment resistant and eligible for clozapine. However, only 7.8% of the sample received clozapine, indicating that this medication was underprescribed. A lower baseline GAF score was associated with clozapine use within two years, suggesting that it could be used to facilitate the early identification of patients who will need treatment with clozapine, which could in turn improve treatment outcomes.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does suicide contagion (Werther effect) take place in response to social media? A systematic review.","authors":"Serena Calvo, Juan Pablo Carrasco, Celia Conde-Pumpido, Jose Esteve, Eduardo Jesús Aguilar","doi":"10.1016/j.sjpmh.2024.05.003","DOIUrl":"10.1016/j.sjpmh.2024.05.003","url":null,"abstract":"<p><strong>Introduction: </strong>The Werther, Copycat or contagion effect of suicidal behaviour is a complex phenomenon that can arise due to exposure to media stories in which identifiable people take their lives. On the contrary, the Papageno effect prevents people from suicide by promoting positives examples of suicidal crisis management. Impact of both effects has been widely studied in different types of situations, but its existence in social media is a source of much debate.</p><p><strong>Methods: </strong>A systematic search following the PRISMA guidelines of PubMed, Scopus, Embase, PsycInfo, Web of Science and the references of prior reviews yielded 25 eligible studies.</p><p><strong>Results: </strong>Most of the studies found were observational, with very different methodologies and generally with low risk of bias. In these, the results suggest the existence of the Werther effect in response to social media stories about suicide. This is mediated by multiple factors, including the characteristic of the users, the type of interaction and the content of the publications. At the same time, the Papageno effect is also described. Evidence found by type of social media and future implications are discussed.</p><p><strong>Conclusion: </strong>Suicidal content on social media can be both contagious and protective. It is confirmed that the Werther and Papageno effects may occur in response to social media, so they could be an interesting target for preventive interventions.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141289099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of health services use and clinical profiles in the year prior to suicide between 2010 and 2018: An opportunity to improve its prevention.","authors":"Andrea Gabilondo, Ana Gonzalez-Pinto, Jon Garcia, David Del Valle, Benito Morentin, Alvaro Iruin","doi":"10.1016/j.sjpmh.2024.05.002","DOIUrl":"10.1016/j.sjpmh.2024.05.002","url":null,"abstract":"<p><strong>Introduction: </strong>Suicide is the first cause of external death in Spain. International studies show frequent and varied health contacts in the months prior to suicide. There are hardly any studies on that phenomenon in this country.</p><p><strong>Objective: </strong>To analyze health care use in the year prior to suicide between 2010 and 2018 in the Basque Country, as well as pharmacological prescriptions and psychiatric diagnoses received.</p><p><strong>Methods: </strong>Retrospective descriptive study with all suicides registered by the Basque Institute of Legal Medicine (BILM) between 2010 and 2018. The records of the BILM and the Basque Health Service (Osakidetza) were cross-checked.</p><p><strong>Results: </strong>1526 suicides were analyzed. 74% had health contacts in the previous year. The use was higher in women (p<0.05) and in older ages (p<0001). Primary care was the most used specialty (58.8% the previous year and 7.1% the previous week), followed by Hospital Emergencies (50.3% and 10.2%) and Outpatient Medical Specialties (49% and 11.6%), especially Radiology. Outpatient psychiatry only contacted 29.6% that year, although it had the highest average number of visits (15.1 SD22.6). The most frequent diagnostic category among psychiatric patients was F30-39 (26.7%), with differences between sexes and ages. 49.7% received psychotropic drugs.</p><p><strong>Conclusions: </strong>The results are aligned with international evidence, which they also extend, and reinforce the need to extend prevention beyond psychiatric services. It seems advisable to increase proactivity in the search for risk by sensitizing and training different professional profiles, but also to work from non-health settings to improve assistance to highly vulnerable profiles (young men) with low health links.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tobacco use disorder and other mental disorders: The neglected dual disorder.","authors":"Carlos Parro-Torres, Miquel Casas, José Martínez-Raga, Ma Cristina Pinet Ogué, Pilar Alejandra Sáiz Martínez, Néstor Szerman","doi":"10.1016/j.sjpmh.2024.04.002","DOIUrl":"10.1016/j.sjpmh.2024.04.002","url":null,"abstract":"","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammation and weight change related to neurocognitive and functional impairment in diabetes and psychiatric disorders.","authors":"Joan Vicent Sánchez-Ortí, Vicent Balanzá-Martínez, Patricia Correa-Ghisays, Gabriel Selva-Vera, Joan Vila-Francés, Rafael Magdalena-Benedito, Constanza San-Martin, Víctor M Victor, Irene Escribano-Lopez, Antonio Hernandez-Mijares, Juliana Vivas-Lalinde, Benedicto Crespo-Facorro, Rafael Tabarés-Seisdedos","doi":"10.1016/j.sjpmh.2024.05.001","DOIUrl":"10.1016/j.sjpmh.2024.05.001","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity is a global pandemic associated with various cardio-metabolic and psychiatric disorders. Neurocognitive and functional deficits have been associated with several somatic and psychiatric disorders. Adiposity-related inflammation has recently emerged as a key risk factor for neurocognitive and functional impairments. This prospective transdiagnostic study aimed to investigate the role of adiposity-related inflammatory markers in neurocognitive and functional outcomes associated with weight changes.</p><p><strong>Methods: </strong>Peripheral blood inflammatory and oxidative stress biomarkers and neurocognitive and functional performance were assessed twice over 1 year in 165 individuals, including 30 with schizophrenia, 42 with bipolar disorder, 35 with major depressive disorder, 30 with type 2 diabetes mellitus (T2DM), and 28 healthy controls. Participants were stratified by body mass index into categories of type 2 obesity (T2OB; n=30), type 1 obesity (T1OB; n=42), overweight (OW; n=53), and average weight (NW; n=40). Mixed one-way analysis of covariance and linear and binary logistic regression analyses were performed.</p><p><strong>Results: </strong>Compared with NW, T2OB and T1OB were significantly associated with impaired neurocognitive and functional performance (p<0.01; η²p=0.06-0.12) and higher levels of C-reactive protein and platelets (PLT) (p<0.01; η²p=0.08-0.16), with small-to-moderate effect sizes. IL-6, IL-10, and PLT were key factors for detecting significant weight changes in T1OB and T2OB over time. Regression models revealed that inflammatory and oxidative stress biomarkers and cellular adhesion molecules were significantly associated with neurocognitive and functional performance (p<0.05).</p><p><strong>Discussion: </strong>Obesity is characterized by neurocognitive and functional impairments alongside low-grade systemic inflammation. Adiposity-related inflammatory biomarkers may contribute to neurocognitive and functional decline in individuals with T2DM and psychiatric disorders. Our data suggest that these biomarkers facilitate the identification of specific subgroups of individuals at higher risk of developing obesity.</p>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of social phobia in Andalusia","authors":"Pablo González-Domenech ,&nbsp;Blanca Gutiérrez ,&nbsp;José Eduardo Muñoz-Negro ,&nbsp;Esther Molina ,&nbsp;Margarita Rivera ,&nbsp;Jorge A. Cervilla","doi":"10.1016/j.rpsm.2021.09.006","DOIUrl":"10.1016/j.rpsm.2021.09.006","url":null,"abstract":"<div><h3>Introduction</h3><p>Population studies on social anxiety disorder (SAD) are relatively scarce and there is no previous reported evidence on prevalence or correlates of SAD in an Andalusian general population sample.</p></div><div><h3>Material and methods</h3><p>We used a random representative sample previously identified via standard stratification procedures. Thus, a final sample of 4507 participants were included (response rate 83.7%). Interviewees were thoroughly assessed on sociodemographic, clinical and psychosocial factors, including: exposures to threatening life events (TLEs), childhood abuse, personality disorder and traits (neuroticism, impulsivity, paranoia), global functioning, physical health and toxics consumption. SAD diagnosis was ascertained using the Mini International Neuropsychiatric Interview. Both, pooled prevalences (with 95% confidence intervals) and risk correlates for SAD were estimated using binary logistic regression.</p></div><div><h3>Results</h3><p>Estimated prevalence for SAD was 1.1% (95% CI<!--> <!-->=<!--> <!-->0.8-1.4). Having a SAD diagnosis was independently and significantly associated with younger age, poorer global functioning, higher neuroticism and paranoia personality traits, having suffered childhood abuse and exposure to previous TLEs. Furthermore, SAD was significantly associated with comorbid personality disorder, major depression, panic disorder and alcohol abuse.</p></div><div><h3>Conclusions</h3><p>Among this large Andalusian population sample, the prevalence of SAD and its associated factors are relatively similar to previously reported international studies, although no population study had previously reported such a strong association with paranoia.</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 88-94"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S188898912100118X/pdfft?md5=af5c427f33f7345bcb88d06413d047fc&pid=1-s2.0-S188898912100118X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88244362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRimary carE digital Support ToOl in mental health (PRESTO): Design, development and study protocols","authors":"Gerard Anmella ,&nbsp;Mireia Primé-Tous ,&nbsp;Xavier Segú ,&nbsp;Aleix Solanes ,&nbsp;Victoria Ruíz ,&nbsp;Inés Martín-Villalba ,&nbsp;Ivette Morilla ,&nbsp;Antonieta Also-Fontanet ,&nbsp;Elisenda Sant ,&nbsp;Sandra Murgui ,&nbsp;Mireia Sans-Corrales ,&nbsp;Andrea Murru ,&nbsp;Roland Zahn ,&nbsp;Allan H. Young ,&nbsp;Victor Vicens ,&nbsp;Clara Viñas-Bardolet ,&nbsp;Juan Francisco Martínez-Cerdá ,&nbsp;Jordi Blanch ,&nbsp;Joaquim Radua ,&nbsp;Miquel-Àngel Fullana ,&nbsp;Diego Hidalgo-Mazzei","doi":"10.1016/j.rpsm.2021.04.003","DOIUrl":"10.1016/j.rpsm.2021.04.003","url":null,"abstract":"<div><h3>Background</h3><p><span>About 30–50% of Primary Care (PC) users in Spain suffer mental health problems, mostly mild to moderate anxious and depressive symptoms, which account for 2% of Spain's total Gross domestic product and 50% of the costs associated to all </span>mental disorders<span>. Mobile health tools have demonstrated to cost-effectively reduce anxious and depressive symptoms while machine learning (ML) techniques have shown to accurately detect severe cases. The main aim of this project is to develop a comprehensive ML digital support platform (PRESTO) to cost-effectively screen, assess, triage, and provide personalized treatments for anxious and depressive symptoms in PC.</span></p></div><div><h3>Methods</h3><p>The project will be carried out in 3 complementary phases: First, a ML predictive severity model will be built based on all the cases referred to the PC mental health support programme during the last 5 years in Catalonia. Simultaneously, a smartphone app to monitor and deliver psychological interventions for anxiety and depressive symptoms will be developed and tested in a clinical trial<span>. Finally, the ML models and the app will be integrated in a comprehensive decision-support platform (PRESTO) which will triage and assign to each patient a specific intervention based on individual personal and clinical characteristics. The effectiveness of PRESTO to reduce waiting times in receiving mental healthcare will be tested in a stepped-wedge cluster randomized controlled trial in 5 PC centres.</span></p></div><div><h3>Discussion</h3><p>PRESTO will offer timely and personalized cost-effective mental health treatment to people with mild to moderate anxious and depressive symptoms. This will result in a reduction of the burden of mental health problems in PC and on society as a whole.</p></div><div><h3>Trial registration</h3><p>The project and their clinical trials were registered in Clinical Trials.gov: <span>NCT04559360</span><svg><path></path></svg> (September 2020).</p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 114-125"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38870878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Adult Attachment Questionnaire-Revised (CAA-r)","authors":"Remedios Melero ,&nbsp;María José Cantero","doi":"10.1016/j.rpsm.2021.09.003","DOIUrl":"10.1016/j.rpsm.2021.09.003","url":null,"abstract":"<div><p>The Adult Attachment Questionnaire-Revised and its psychometric<span> properties are presented for dimensional and categorical evaluation of adult attachment style. Eight items were added to the original questionnaire (CAA; Melero and Cantero, 2008) that expanded avoidance dimension assessment and sensitivity evaluation. The exploratory factor analysis EFA led to 35 items grouped in 4 affective dimensions. (1) Anxiety: Need for approval, negative self-esteem, fear for rejection/abandonment and relationship anxiety; (2) Socioemotional competence: Emotional openness, sensitivity, and confidence; (3) Avoidance: Self-reliance and emotional discomfort with intimacy, and (4) Anger: Resentment, anger and intransigence. The cluster analysis confirmed the categorization of the 4 styles of attachment described by Bartholomew (Bartholomew and Horowitz, 1991). The questionnaire showed satisfactory levels of reliability and validity.</span></p></div>","PeriodicalId":101179,"journal":{"name":"Spanish Journal of Psychiatry and Mental Health","volume":"17 2","pages":"Pages 81-87"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90353349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}