Science in One Health最新文献

{"title":"Fieldwork on animals living in extreme conditions as a source of biomedical innovation","authors":"Yvon Le Maho ,&nbsp;Aurélie Tasiemski ,&nbsp;Fabrice Bertile ,&nbsp;Philippe Bulet","doi":"10.1016/j.soh.2024.100096","DOIUrl":"10.1016/j.soh.2024.100096","url":null,"abstract":"<div><div>Most biomedical research on animals is based on the handful of the so-called standard model organisms, i.e. laboratory mice, rats or <em>Drosophila</em>, but the keys to some important biomedical questions may simply not be found in these. However, compared with the high number of molecules originating from plants in clinical use, and with the countless unique adaption mechanisms that animals have developed over the course of evolution to cope with environmental constrains, there is still few investigations on wild animals with biomedical objectives, and field studies are far fewer. A major limitation is insufficient funding, the main causes of which we analyze. We argue, however, that fieldwork is a key driver in generating new scientific knowledge as part of a One Health approach, by observing/documenting and understanding the diverse and largely unexplored biological processes evolved by animals adapted to unusual environmental conditions, which would be extreme conditions for humans. These conditions do not only refer to extreme temperatures, since lack of food or water, high pressures or lack of oxygen, are clearly extreme constraints. To conduct this research, there are serious limitations we propose to address. Specific techniques and methods are requested, not only to work in extreme environments, but also to minimize the ecological footprint of field work. The erosion of biodiversity is a major threat. The reduction of animal disturbance, a key issue, requires specific technologies and expertise. An ethical approach is requested, for the sake of transparency and to comply with the Nagoya Protocol on genetic resources. An interdisciplinary expertise and a meticulous planning are requested to overcome the field constraints and interface the associated laboratory work. We recommend focusing on the major threats to global human health today, which wild animals appear to resist particularly well, such as antibioresistance and diseases associated with lifestyle and senescence.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100096"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of sentinel surveillance and climate factors to accelerate malaria elimination in a changing climate of Senegal","authors":"Ibrahima Mamby Keita ,&nbsp;Mariama Diouf ,&nbsp;Medoune Ndiop ,&nbsp;Boly Diop ,&nbsp;Khaly Gueye ,&nbsp;Marianne Kouawo ,&nbsp;Ousmane Ndiaye ,&nbsp;Doudou Sene ,&nbsp;Elhadji Mamadou Ndiaye ,&nbsp;Marie Khemesse Ngom Ndiaye","doi":"10.1016/j.soh.2025.100112","DOIUrl":"10.1016/j.soh.2025.100112","url":null,"abstract":"<div><h3>Background</h3><div>Senegal is located in a malaria-endemic zone. Malaria is a highly climate-sensitive vector-borne disease, yet its sentinel surveillance shows a weak integration of malaria morbidity data with climatic factors. Therefore, it is useful to analyse the correlation between these factors in Senegal from 2012 to 2019.</div></div><div><h3>Methods</h3><div>An analytical cross-sectional study of malaria incidence rate (MIR) with its climatic factors from 2012 to 2019 was carried out. This was followed by predictive modelling of MIR and its climatic factors from 2020 to 2023. A reconstituted database, incorporating data from National Malaria Control Program (initiated by Ministry of Health) and National Agency for Civil Aviation and Meteorology, enabled a multi-variate analysis through a vector auto regression approach using <em>Microsoft Excel 2010</em> and <em>R 3.6.1</em> software.</div></div><div><h3>Results</h3><div>MIR evolved in three phases: initially almost zero from January to May, then gradually increases with an accentuation in August–September, and finally gradually decreases from November to December. However, unlike Podor (0.11 ‰), MIR heterogeneity was seen in Kédougou (12.55 ‰) and Bakel (7.34 ‰). Apart from wind strength and mean temperature which moved in the opposite directions, all other climatic factors evolved in the same dynamics as MIR. MIR followed changes in rainfall and hygrometry with an average lag of (2.5 ± 1.0) months and (1.0 ± 0.5) months, respectively. The causal links between MIR and rainfall showed a decreasing trend in Dakar (<em>P</em> = 4.18 × 10⁻⁶), Ziguinchor (<em>P</em> = 7.95 × 10⁻⁴), Diourbel (<em>P</em> = 1.91 × 10⁻³), Kédougou (<em>P</em> = 4.03 × 10⁻³), and Bakel (<em>P</em> = 3.32 × 10⁻²). In Bakel, additional associations were observed between MIR and both minimum temperature (<em>P</em> = 5.87 × 10⁻³) and maximum temperature (<em>P</em> = 1.22 × 10⁻²) temperatures. Predictive modelling shows an overall downward trend for MIR from 2020 to 2023, with its climatic factors preceding MIR by an average of two months.</div></div><div><h3>Conclusion</h3><div>This study highlights the importance of synchronous, multi-sectoral, and integrated surveillance of malaria alongside climatic factors to more effectively meet pre-elimination requirements in Senegal.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100112"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tackling antimicrobial resistance in the food chain under the One Health umbrella: a systems thinking approach with a focus on Jordan","authors":"Ala'a B. Al-Tammemi ,&nbsp;Salam Momani ,&nbsp;Hanan Hasan ,&nbsp;Amal Obeidat ,&nbsp;Muna Horabi","doi":"10.1016/j.soh.2025.100115","DOIUrl":"10.1016/j.soh.2025.100115","url":null,"abstract":"<div><div>Antimicrobial resistance (AMR) has emerged as a critical public health threat and one of the most complicated global challenges due to its multi-faceted nature. In addition to health burden, AMR also drives up healthcare costs and imposes substantial indirect economic impacts. Despite the ongoing global efforts, the burden of drug-resistant infections is still growing and alarming. Although AMR has been well addressed pertaining to human health, AMR linked to pathogens in other pillars of the food chain has been a hidden menace and a growing public health concern. AMR may arise in the food chain through various pathways, with foodborne drug-resistant pathogens being reported in the literature. Tackling and combatting AMR in the food chain requires a multi-faceted comprehensive approach under the One Health umbrella. This approach is crucial not only to protect public health but also to ensure the sustainability and safety of all components of the food chain.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100115"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Milk and meat safety in Nepal: addressing challenges and exploring solutions","authors":"Deepak Subedi ,&nbsp;Sameer Thakur ,&nbsp;Anil Gautam ,&nbsp;Madhav Poudel ,&nbsp;Sumit Jyoti ,&nbsp;Abhinandan Devkota ,&nbsp;Milan Kandel ,&nbsp;Ananda Tiwari","doi":"10.1016/j.soh.2025.100116","DOIUrl":"10.1016/j.soh.2025.100116","url":null,"abstract":"<div><div>The transmission of zoonotic diseases through animal-derived food products poses a significant global public health challenge, with contaminated milk and meat serving as major transmission pathways. In Nepal, the growing consumption of these products has amplified the risk of foodborne illnesses, largely due to widespread bacterial contamination. This review systematically explores the prevalence, distribution, and public health significance of key bacterial pathogens, including <em>Salmonella, Escherichia coli</em>, <em>Shigella</em>, <em>Staphylococcus aureus</em>, <em>Brucella</em>, <em>Bacillus cereus</em>, <em>Mycobacterium tuberculosis</em>, and <em>Campylobacter</em> in Nepalese milk and meat products. The analysis identifies major contributing factors: inadequate hygiene and sanitation practices, weak regulatory frameworks, insufficient infrastructure, improper antibiotic usage, and limited public awareness. The high levels of bacterial contamination, coupled with the emergence of antibiotic-resistant strains, underscore the urgency for strategic interventions. Recommended measures include strict enforcement of hygiene and sanitation standards, strengthening regulatory policies, enhancing infrastructure, comprehensive public education campaigns, and prudent antibiotic stewardship. Implementation of these strategies is imperative to improve food safety, protect public health, and mitigate the risks posed by bacterial zoonotic diseases in Nepal.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mpox (monkeypox): a comprehensive updated of current epidemic evidence","authors":"Amir Hossain ,&nbsp;Md. Abdul Monem ,&nbsp;Mamunur Rahman ,&nbsp;Rashadur Raza","doi":"10.1016/j.soh.2024.100100","DOIUrl":"10.1016/j.soh.2024.100100","url":null,"abstract":"<div><div>Mpox, formerly referred to as monkeypox, is a viral disease endemic to central Africa, resulting from the monkeypox virus (MPXV). This study provides a current overview of the Mpox epidemic as of 2024, emphasizing significant developments and epidemiological trends. The World Health Organization (WHO) initially designated a clade Ⅱb outbreak as a global health emergency in May 2022, which was subsequently managed through vaccination and public health interventions by May 2023. In September 2023, a resurgence of cladeⅠ in the Democratic Republic of the Congo (DRC) resulted in a 160 % increase in cases by 2024. The WHO declared this increase a public health emergency of international concern (PHEIC) in August 2024. The outbreak timeline indicates substantial rises in cases and fatalities, especially among children under 15 in the DRC. Regional analysis reveals that the European Region initially recorded the highest incidence of cases and fatalities. In contrast, regions including African Region (AFRO), Eastern Mediterranean Region (EMRO), South-East Asia Region (SEARO), and Western Pacific Region (WPRO) exhibited a rise in cases, indicating a potential spread or resurgence of the health event. Gender disparities in transmission pathways were apparent, with males exhibiting higher case numbers, particularly via person-to-person contact. The research highlights the necessity of ongoing surveillance, global collaboration, and focused public health measures. The discourse addresses obstacles in vaccine distribution and the necessity for emergency use authorizations, highlighting the imperativeness for adaptive strategies in public health management. This extensive update offers critical insights into the present condition of the Mpox epidemic and the necessary measures to mitigate its proliferation.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategy and mechanism of One Health governance: case study of China","authors":"Xinchen Li ,&nbsp;Yanyan Zhang ,&nbsp;Qiyu Zhang ,&nbsp;Jingshu Liu ,&nbsp;Zelin Zhu ,&nbsp;Xinyu Feng ,&nbsp;Lefei Han ,&nbsp;Xiaoxi Zhang","doi":"10.1016/j.soh.2024.100098","DOIUrl":"10.1016/j.soh.2024.100098","url":null,"abstract":"<div><h3>Background</h3><div>Strategy and mechanism are crucial components of One Health governance in China, designed to address the interconnected health issues between humans, animals, and the environment. This study aims to evaluate China's current One Health governance framework, identify key strengths and gaps, and provide recommendations for establishing a more integrated and effective system.</div></div><div><h3>Methods</h3><div>A qualitative approach was employed, including in-depth interviews, policy analysis, and a review of existing literature, to evaluate the strengths and gaps in China's One Health framework.</div></div><div><h3>Results</h3><div>The analysis identified progress and challenges in six key areas: (1) political commitment: strong national support exists, but lacks a unified strategy; (2) legislation and regulation: notable legislative efforts are in place, yet they remain fragmented; (3) leadership building: effective leadership structures have been established during crises but are not institutionalized; (4) strategic planning: initial regional planning is underway, but a comprehensive national focus is needed; (5) coordination and communication: mechanisms exist but require formalized, consistent information-sharing channels; (6) stakeholder engagement: public and academic awareness is growing, yet local community involvement needs strengthening.</div></div><div><h3>Conclusion</h3><div>To advance its One Health governance, China must focus on creating a unified strategy, enhancing interdepartmental coordination, and deepening stakeholder engagement, ensuring its alignment with international standards and improving public health outcomes.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100098"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulating antimicrobial resistance in the environment: analysis of Thailand legal framework and areas for reinforcement","authors":"Angkana Lekagul ,&nbsp;Saowapa Khotchalai ,&nbsp;Wanwisa Kaewkhankhaeng ,&nbsp;Mary Gordoncillo ,&nbsp;Fuangfa Utrarachkij ,&nbsp;Viroj Tangcharoensathien","doi":"10.1016/j.soh.2025.100110","DOIUrl":"10.1016/j.soh.2025.100110","url":null,"abstract":"<div><h3>Background</h3><div>Antimicrobial resistance (AMR) is a pressing global health issue, exacerbated by extensive antimicrobial use across human, animal, and plant sectors. The environment plays a crucial role in AMR emergence and spread due to the contamination from resistant bacteria, resistance genes, and antimicrobial residues from various sources. In Thailand, the regulatory framework that can reinforce AMR mitigation in environmental settings remains underdeveloped. This study aims to analyse the existing regulatory framework for environmental AMR control by identifying regulatory gaps and assessing the challenges of implementing these regulations.</div></div><div><h3>Methods</h3><div>A qualitative approach was employed, combining a literature review and semi-structured interviews with 28 key informants from diverse regulatory sectors, including the ministries of health, agriculture, and environment. This included multi-level stakeholders at national, provincial, and local levels, as well as selected farmers. Content analysis of interview transcripts and regulatory documents was performed to triangulate findings on regulatory gaps and implementation barriers.</div></div><div><h3>Results</h3><div>The study identified five regulatory categories governing water contamination across settings: rivers/canals, hospital wastewater, household wastewater, industrial waste (including pharmaceuticals), and animal farms. While the regulatory frameworks guide pollution standards, regulations lack provisions specific to AMR, highlighting a significant gap in AMR oversight and data on AMR pathogens in environmental wastewater. Key barriers include insufficient incorporation of AMR indicators in routine monitoring, limited enforcement, and inadequate technical and budgetary support.</div></div><div><h3>Conclusion</h3><div>Thailand's current environmental AMR framework lacks comprehensive AMR-specific regulations and robust enforcement mechanisms. Addressing these gaps requires multi-sectoral coordination, enhanced funding, and capacity-building initiatives. By prioritizing indicator development and establishing AMR-focused policies, Thailand can enhance its environmental AMR control measures and contribute to global AMR mitigation efforts.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100110"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144107542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Health: governance and regulatory framework for antimicrobial use in Malawi","authors":"Amos Lucky Mhone ,&nbsp;Dishon M. Muloi ,&nbsp;Arshnee Moodley","doi":"10.1016/j.soh.2025.100119","DOIUrl":"10.1016/j.soh.2025.100119","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Antimicrobial resistance (AMR) poses a global threat to both human and animal health, associated with widespread use of antimicrobials across sectors. In low- and middle-income countries (LMICs) such as Malawi, weak regulatory frameworks and limited enforcement capacity contribute to inappropriate use of antibiotics. This study examined the governance and regulatory frameworks for antimicrobial use (AMU) in Malawi's agricultural sector, identified regulatory gaps, and offers recommendations to antimicrobial stewardship.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A qualitative approach was used, combining a review of policy and legal documents with semi-structured stakeholder interviews. Relevant policies and laws were sourced from government databases, the Food and Agricultural Organisation of the United Nations' (FAO) FAOLEX and AMR-LEX databases, and other publicly available resources. The FAO's legal assessment methodology was used to evaluate the policy landscape across nine key thematic areas: (1) veterinary medicinal products, (2) animal health and production practices to prevent animal diseases in terrestrial and aquatic animals, (3) feed registration, (4) pesticides, (5) food safety, (6) environment, soil and waste, (7) water quality, (8) plant health, and (9) institutional coordination. Stakeholder interviews with representatives from relevant government ministries and regulatory bodies validated findings from the document review and provided additional insight into governance challenges. A One Health governance mapping exercise was conducted to identify key institutional actors, assess their role in AMR/AMU governance, and evaluate inter-institutional relationships using social network analysis.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The analysis identified 522 policies relevant to AMU in agriculture, with most addressing aquatic animal health (11.3 %, &lt;em&gt;n&lt;/em&gt; = 59), food safety (10.9 %, &lt;em&gt;n&lt;/em&gt; = 57) and animal feed (10.9 %, &lt;em&gt;n&lt;/em&gt; = 57). Several critical regulatory gaps were identified, including the absence of a legal definition for “antimicrobials,” a national essential veterinary medicines list, and standardized veterinary treatment guidelines. Additionally, there are no restrictions on the use of critically important antimicrobials for human health in veterinary settings, minimal oversight of antimicrobial-medicated feed, and no established protocols for on-farm antimicrobial disposal. Stakeholder mapping revealed limited knowledge sharing among institutions and a dependence on international donors for AMR/AMU-related activities, raising concerns about the sustainability of current initiatives. Malawi also lacks an integrated AMR and AMU monitoring system, a national prioritised AMR research agenda, and clear targets for reducing AMU in animals.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;To address these gaps, we recommend that Malawi: (1) establish a comprehensive AMR and AMU monitoring program, (2) up","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144831351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of potentially zoonotic Rickettsia species in dogs and their attached ticks in Malawi through the lens of One Health","authors":"Elisha Chatanga ,&nbsp;Henson Kainga ,&nbsp;John Kothowa ,&nbsp;Michael Luwe ,&nbsp;Richard Ssuna ,&nbsp;Tinotenda Razemba ,&nbsp;Laston Chimaliro ,&nbsp;Naoki Hayashi ,&nbsp;Yuki Ohsugi ,&nbsp;Yongjin Qiu ,&nbsp;Kyoko Hayashida ,&nbsp;Nariaki Nonaka ,&nbsp;Ryo Nakao","doi":"10.1016/j.soh.2025.100122","DOIUrl":"10.1016/j.soh.2025.100122","url":null,"abstract":"<div><h3>Background</h3><div>The genus <em>Rickettsia</em> in the order Rickettsiales (Alphaproteobacteria) consists of gram-negative obligate intracellular bacteria that infect a wide range of hosts. Epidemiological studies on the occurrence of <em>Rickettsia</em> spp. and their associated tick vectors are essential to understand their distribution, host range, and transmission mechanisms in nature. This is particularly relevant within the One Health framework, which emphasizes the interconnectedness of animal, human, and environmental health.</div></div><div><h3>Methods</h3><div>To investigate the presence of <em>Rickettsia</em> spp. in dogs and their ticks in Malawi, a molecular survey was conducted. A total of 209 dog blood and 259 tick samples of the species <em>Haemaphysalis elliptica</em> (<em>n</em> = 16) and <em>Rhipicephalus linnaei</em> (<em>n</em> = 243) were screened using real-time quantitative PCR (qPCR) targeting the citrate synthase (<em>gltA</em>) gene. Positive samples were further characterized via the conventional PCR and Sanger sequencing of <em>gltA</em> and the outer membrane protein A (<em>ompA</em>) genes.</div></div><div><h3>Results</h3><div><em>Rickettsia</em> DNA was not detected in any dog samples. However, the detection rates in <em>R</em>. <em>linnaei</em> and <em>H. elliptica</em> were 2.5 % (<em>n</em> = 6) and 6.3 % (<em>n</em> = 1), respectively. The obtained sequences showed 100 % identity with <em>Rickettsia conorii</em> subsp. <em>conorii</em> (<em>n</em> = 4), 99 %–100 % with <em>Rickettsia massiliae</em> (<em>n</em> = 2), and 100 % with <em>Rickettsia rhipicephali</em> (<em>n</em> = 1). Phylogenetic analysis clustered these sequences with the corresponding sequences of <em>R</em>. <em>conorii</em> subsp. <em>conorii</em>, <em>R</em>. <em>massiliae</em>, and <em>R</em>. <em>rhipicephali</em> reported from other countries in both <em>gltA</em> and <em>ompA</em> gene-based phylogenetic trees. The detection of <em>R</em>. <em>massiliae</em> and <em>R</em>. <em>rhipicephali</em> in southern Africa suggests expansion of the geographical distribution of these potentially zoonotic <em>Rickettsia</em> species.</div></div><div><h3>Conclusion</h3><div>This is the first report of <em>Rickettsia</em> species detection in ticks collected from dogs in Malawi. The findings highlight the need for further surveillance, including humans and other animals, to better assess the public and veterinary health risks. Public engagement is needed to raise awareness on the role of dogs and their ticks in the transmission of <em>Rickettsia</em> within the One Health approach.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk assessment of emerging infectious diseases in China under the One Health framework","authors":"Ne Qiang ,&nbsp;Tianyun Li ,&nbsp;Lijun Jia ,&nbsp;Zelin Zhu ,&nbsp;Xinyu Feng ,&nbsp;Jinjun Ran ,&nbsp;Xiaoxi Zhang ,&nbsp;Lefei Han","doi":"10.1016/j.soh.2025.100104","DOIUrl":"10.1016/j.soh.2025.100104","url":null,"abstract":"<div><h3>Background</h3><div>Emerging infectious diseases (EIDs) pose significant public health challenges due to increasing interactions between humans, animals, and the environment. The One Health framework, an interdisciplinary and collaborative approach, plays a critical role in the risk assessment of EIDs. The study aims to systematically review the risk assessment of EIDs in China under the One Health framework, covering policy support, monitoring and assessment systems, and implementation methods.</div></div><div><h3>Methods</h3><div>Relevant literature and official documents between 1997 and 2024 were retrieved from Web of Science, PubMed, Scopus, China National Knowledge Infrastructure, Wan Fang, China Science and Technology Journal Database, and government websites. Data were synthesized to analyze progress, challenges, and gaps.</div></div><div><h3>Results</h3><div>There were 43 academic studies and 31 official documents included in this review. The study found that risk assessment systems existed across human, animal, and environmental health sectors in China, and the government was advancing intelligent monitoring and fostering inter-departmental cooperation. However, several challenges remain in risk assessment of EIDs, including inadequate monitoring systems for unknown EIDs, limited capacity building for risk assessment in ecosystems and environmental systems, insufficiently detailed risk assessment guidance at the county level, and barriers to cross-sectoral information sharing at the international and county levels.</div></div><div><h3>Conclusion</h3><div>The findings highlighted the need to enhance risk assessment of EIDs at the local level, expand the scope of disease surveillance including aquatic and wild animals, and strengthen inter-departmental data sharing to improve early warning capabilities under the One Health framework.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100104"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}