Science in One Health最新文献

{"title":"Regulating antimicrobial resistance in the environment: analysis of Thailand legal framework and areas for reinforcement","authors":"Angkana Lekagul ,&nbsp;Saowapa Khotchalai ,&nbsp;Wanwisa Kaewkhankhaeng ,&nbsp;Mary Gordoncillo ,&nbsp;Fuangfa Utrarachkij ,&nbsp;Viroj Tangcharoensathien","doi":"10.1016/j.soh.2025.100110","DOIUrl":"10.1016/j.soh.2025.100110","url":null,"abstract":"<div><h3>Background</h3><div>Antimicrobial resistance (AMR) is a pressing global health issue, exacerbated by extensive antimicrobial use across human, animal, and plant sectors. The environment plays a crucial role in AMR emergence and spread due to the contamination from resistant bacteria, resistance genes, and antimicrobial residues from various sources. In Thailand, the regulatory framework that can reinforce AMR mitigation in environmental settings remains underdeveloped. This study aims to analyse the existing regulatory framework for environmental AMR control by identifying regulatory gaps and assessing the challenges of implementing these regulations.</div></div><div><h3>Methods</h3><div>A qualitative approach was employed, combining a literature review and semi-structured interviews with 28 key informants from diverse regulatory sectors, including the ministries of health, agriculture, and environment. This included multi-level stakeholders at national, provincial, and local levels, as well as selected farmers. Content analysis of interview transcripts and regulatory documents was performed to triangulate findings on regulatory gaps and implementation barriers.</div></div><div><h3>Results</h3><div>The study identified five regulatory categories governing water contamination across settings: rivers/canals, hospital wastewater, household wastewater, industrial waste (including pharmaceuticals), and animal farms. While the regulatory frameworks guide pollution standards, regulations lack provisions specific to AMR, highlighting a significant gap in AMR oversight and data on AMR pathogens in environmental wastewater. Key barriers include insufficient incorporation of AMR indicators in routine monitoring, limited enforcement, and inadequate technical and budgetary support.</div></div><div><h3>Conclusion</h3><div>Thailand's current environmental AMR framework lacks comprehensive AMR-specific regulations and robust enforcement mechanisms. Addressing these gaps requires multi-sectoral coordination, enhanced funding, and capacity-building initiatives. By prioritizing indicator development and establishing AMR-focused policies, Thailand can enhance its environmental AMR control measures and contribute to global AMR mitigation efforts.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100110"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144107542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk assessment of emerging infectious diseases in China under the One Health framework","authors":"Ne Qiang ,&nbsp;Tianyun Li ,&nbsp;Lijun Jia ,&nbsp;Zelin Zhu ,&nbsp;Xinyu Feng ,&nbsp;Jinjun Ran ,&nbsp;Xiaoxi Zhang ,&nbsp;Lefei Han","doi":"10.1016/j.soh.2025.100104","DOIUrl":"10.1016/j.soh.2025.100104","url":null,"abstract":"<div><h3>Background</h3><div>Emerging infectious diseases (EIDs) pose significant public health challenges due to increasing interactions between humans, animals, and the environment. The One Health framework, an interdisciplinary and collaborative approach, plays a critical role in the risk assessment of EIDs. The study aims to systematically review the risk assessment of EIDs in China under the One Health framework, covering policy support, monitoring and assessment systems, and implementation methods.</div></div><div><h3>Methods</h3><div>Relevant literature and official documents between 1997 and 2024 were retrieved from Web of Science, PubMed, Scopus, China National Knowledge Infrastructure, Wan Fang, China Science and Technology Journal Database, and government websites. Data were synthesized to analyze progress, challenges, and gaps.</div></div><div><h3>Results</h3><div>There were 43 academic studies and 31 official documents included in this review. The study found that risk assessment systems existed across human, animal, and environmental health sectors in China, and the government was advancing intelligent monitoring and fostering inter-departmental cooperation. However, several challenges remain in risk assessment of EIDs, including inadequate monitoring systems for unknown EIDs, limited capacity building for risk assessment in ecosystems and environmental systems, insufficiently detailed risk assessment guidance at the county level, and barriers to cross-sectoral information sharing at the international and county levels.</div></div><div><h3>Conclusion</h3><div>The findings highlighted the need to enhance risk assessment of EIDs at the local level, expand the scope of disease surveillance including aquatic and wild animals, and strengthen inter-departmental data sharing to improve early warning capabilities under the One Health framework.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100104"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human-wildlife conflict and its consequences in Tanzania: advocating the use of One Health approach as a mitigation measure","authors":"Mikidadi Muhanga","doi":"10.1016/j.soh.2025.100109","DOIUrl":"10.1016/j.soh.2025.100109","url":null,"abstract":"<div><div>Globally, human, livestock, and wildlife interactions have been reported to result in innumerable forms of conflict and consequences. The most notable consequences are on the environment and human health, among others. The least developed countries, Tanzania inclusive, due to their bio-geographical and social characteristics, are mostly reported to register such consequences, which have sometimes led to zoonotic diseases due to the existence of risk factors. The factors include the growth of the human population, absence of infrastructural capacity, and skilled manpower to effectively deal with disease outbreaks and livestock keeping associated lifestyles. This article employs a documentary research method to analyse the human-wildlife conflict (HWC) and its consequences in Tanzania. It further assesses the potential of the One Health approach to curb the consequences of HWC following the introduction of One Health Strategic Plan (2015–2020). This article, therefore, analyses the potential for One Health approach to minimize the undesirable impacts of human, livestock, and wildlife interactions on health. This approach underscores the need for collaborative working efforts involving human, livestock, wildlife, and environmental health professionals and the need for a good understanding of the consequences of the interactions towards the realisation of optimum health for people, animals, and our environment.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100109"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143898533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and antibiotic resistance patterns of Pseudomonas aeruginosa and Acinetobacter baumannii strains isolated from chicken droppings on poultry farms in Gondar city, Northwest Ethiopia","authors":"Mitkie Tigabie ,&nbsp;Muluneh Assefa ,&nbsp;Yalewayker Gashaw ,&nbsp;Azanaw Amare ,&nbsp;Aklilu Ambachew ,&nbsp;Sirak Biset ,&nbsp;Feleke Moges","doi":"10.1016/j.soh.2024.100099","DOIUrl":"10.1016/j.soh.2024.100099","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;&lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; and &lt;em&gt;Acinetobacter baumannii&lt;/em&gt; are common nosocomial pathogens in hospital settings. Recently, they have also been found in non-hospital environments, such as poultry farms. While most studies in Ethiopia have focused on these bacteria's antibiotic resistance patterns in hospitals, information regarding their prevalence and resistance in veterinary settings, particularly poultry farms, is limited. This study aimed to assess the prevalence and antibiotic resistance patterns of &lt;em&gt;P. aeruginosa&lt;/em&gt; and &lt;em&gt;A. baumannii&lt;/em&gt; isolated from chicken droppings on poultry farms.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A cross-sectional study was conducted from March 2022 to June 2022. A total of 87 poultry farms were included in this study, and pooled chicken dropping samples were collected. The samples were subsequently transferred to buffered peptone water and cultured on MacConkey agar. Species of the isolates were identified via routine biochemical tests, including oxidase, catalase, urease, Simon's citrate, sulfide indole motility medium, triple sugar iron agar and growth at temperatures of 37 °C and 42 °C. The Kirby–Bauer disk diffusion technique was used for antibiotic susceptibility testing. The data were entered into &lt;em&gt;EpiData&lt;/em&gt; version 4.6 and then exported to &lt;em&gt;SPSS&lt;/em&gt; version 26 for analysis. Fisher's exact test was used to observe an appropriate association between independent variables and the occurrence of isolates. The results are presented in the text, figures and tables.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Among the 87 poultry farms, 41 (47.1 %) were positive for &lt;em&gt;Pseudomonas&lt;/em&gt; and &lt;em&gt;Acinetobacter&lt;/em&gt;. Among these strains, 24 (27.6 %) &lt;em&gt;P. aeruginosa&lt;/em&gt; strains and 13 (14.9 %) &lt;em&gt;A. baumannii&lt;/em&gt; strains were recovered. &lt;em&gt;P. aeruginosa&lt;/em&gt; showed complete resistance to tetracycline (24, 100.0 %) and trimethoprim-sulfamethoxazole (24, 100.0 %). Additionally, there was a high rate of resistance to ciprofloxacin (13, 54.2 %) and amikacin (12, 50.0 %). Similarly, 13 (100.0 %) &lt;em&gt;A. baumannii&lt;/em&gt; isolates were resistant to tetracycline, and 12 (92.3 %) were resistant to trimethoprim-sulfamethoxazole. However, both isolates presented lower resistance rates to piperacillin-tazobactam (4, 9.8 %) and cefepime (7, 17.1 %). Both &lt;em&gt;A. baumannii&lt;/em&gt; and &lt;em&gt;P. aeruginosa&lt;/em&gt; exhibited multidrug resistance in 10/13 (76.9 %) and 16/24 (66.7 %) of the strains, respectively. The overall prevalence of multidrug resistance in this study was 28/41 (68.3 %).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;This study demonstrated that poultry farms may be potential reservoirs for &lt;em&gt;P. aeruginosa&lt;/em&gt; and &lt;em&gt;A. baumannii,&lt;/em&gt; including antibiotic-resistant strains. This is a significant concern to public health because poultry farmers may be contaminated, increasing their dissemination to the community. Therefore, poultry farmers should improve sanitation and reduc","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143163118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated surveillance and early warning system of emerging infectious diseases in China at community level: current status, gaps and perspectives","authors":"Chenjia Zhou ,&nbsp;Suping Wang ,&nbsp;Chenxi Wang ,&nbsp;Ne Qiang ,&nbsp;Leshan Xiu ,&nbsp;Qinqin Hu ,&nbsp;Wenyu Wu ,&nbsp;Xiaoxi Zhang ,&nbsp;Lefei Han ,&nbsp;Xinyu Feng ,&nbsp;Zelin Zhu ,&nbsp;Leilei Shi ,&nbsp;Peng Zhang ,&nbsp;Kun Yin","doi":"10.1016/j.soh.2024.100102","DOIUrl":"10.1016/j.soh.2024.100102","url":null,"abstract":"<div><div>Emerging infectious diseases (EIDs) pose a significant threat to public health. Effective surveillance and early warning systems that monitor EIDs in a timely manner are crucial for their control. Given that more than half of EIDs are zoonotic, traditional integrated surveillance systems remain inadequate. Despite recent advances in integrated systems in China, there are few systemic reviews on the integrated surveillance and early warning system of EIDs at community level, particularly under the One Health framework. Here, this systematic review summarizes the current status of surveillance advances in China, including the multi-trigger integrated monitor system. It also highlights the mechanisms for embedding the One Health approach into local policy and practice, while identifying challenges and opportunities for improvement. Additionally, guidelines and recommendations are proposed to optimize the integration of multi-sectoral, multi-level and interdisciplinary cooperation at the human–animal–environment interface.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143454718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-impacts of climate change and mitigation strategies in Nigeria: agricultural production and food security","authors":"Godspower Oke Omokaro","doi":"10.1016/j.soh.2025.100113","DOIUrl":"10.1016/j.soh.2025.100113","url":null,"abstract":"<div><div>Climate change poses a significant threat to Nigeria's agricultural sector, which is a cornerstone of its economy and food security. The increasing frequency of extreme weather events, erratic rainfall patterns, and rising temperatures have disrupted agricultural productivity, threatening the livelihoods of millions of Nigerians. Through a comprehensive literature review, synthesizing data from peer-reviewed journals, institutional reports, and credible online sources from 2000 to 2023, this study aims to explore the multi-faceted impacts of climate variability on agricultural production, livestock, fisheries, and food security in Nigeria, and to identify effective adaptation strategies to mitigate these impacts. The findings reveal that climate change has significantly disrupted agricultural productivity in Nigeria, with erratic rainfall, rising temperatures, and extreme weather events leading to reduced crop yields, increased pest and disease pressure, and land degradation. Vulnerable crops such as maize, cassava, and rice are particularly affected, while livestock production faces challenges such as heat stress and reduced feed availability. The fisheries sector is also impacted, with shrinking water resources and increasing contamination levels threatening livelihoods. Adaptation strategies, including crop diversification, improved irrigation, and indigenous knowledge practices, offer some resilience but require substantial policy and financial support. The study highlights the urgency of implementing climate-smart agricultural practices, enhancing infrastructure, and promoting public-private partnerships to mitigate climate-induced risks. Recommendations align with the United Nations Sustainable Development Goals (SDGs) 2 (Zero Hunger), 13 (Climate Action), and 15 (Life on Land), emphasizing the need for sustainable agricultural practices, ecosystem preservation, and adaptive policy frameworks to ensure food security and economic stability in Nigeria. This study provides valuable insights into the impacts of climate change on Nigeria's agricultural sector and offers practical recommendations for building resilience and ensuring sustainable food systems. It reveals the importance of collaborative efforts at all levels to address the challenges posed by climate change and safeguard the nation's agricultural heritage for future generations.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100113"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144168685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mismatched online public concern and tick-borne disease risk in China","authors":"Yuxin Li ,&nbsp;Tengfei Hu ,&nbsp;Tingting Wang ,&nbsp;Sen Li","doi":"10.1016/j.soh.2024.100101","DOIUrl":"10.1016/j.soh.2024.100101","url":null,"abstract":"<div><h3>Introduction</h3><div>Ticks and tick-borne diseases are increasing public health concerns in China. This study examines public awareness and concern using data from the People Cloud, a national public opinion data platform.</div></div><div><h3>Methods</h3><div>We analyzed 358,862 posts related to ticks, tick bites, Lyme disease, and tick-borne encephalitis from October 2022 to November 2023. Temporal trends and geographic distribution were assessed to identify patterns of public interest.</div></div><div><h3>Results</h3><div>Public concern peaked in April, coinciding with tick season, with “ticks” being the most mentioned term, particularly on social media platforms, such as WeChat. High search activity was concentrated in southeastern and northern provinces, especially Zhejiang, Guangdong, and Jiangsu. Lyme disease posts were more dispersed, while tick-borne encephalitis posts clustered in southern areas.</div></div><div><h3>Conclusion</h3><div>Public interest in ticks follows seasonal and regional trends, reflecting tick activity but not always matching disease risk or tick distribution. Monitoring public opinion data can guide targeted health interventions and improve disease prevention efforts.</div></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"4 ","pages":"Article 100101"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143163016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global burden of HIV-negative multidrug- and extensively drug-resistant tuberculosis based on Global Burden of Disease Study 2021","authors":"Yiming Chen ,&nbsp;Weiye Chen ,&nbsp;Zile Cheng ,&nbsp;Yiwen Chen ,&nbsp;Min Li ,&nbsp;Lingchao Ma ,&nbsp;Nan Zhou ,&nbsp;Jing Qian ,&nbsp;Yongzhang Zhu ,&nbsp;Chang Liu","doi":"10.1016/j.soh.2024.100072","DOIUrl":"10.1016/j.soh.2024.100072","url":null,"abstract":"<div><h3>Background</h3><p>Tuberculosis (TB), caused by <em>Mycobacterium tuberculosis</em>, remains the second leading cause of death from a single infectious disease globally and poses a significant economic and clinical burden in the world in 2022. Of particular concern is the emergence of drug-resistant TB, accounting for 15%–20% of TB deaths. It is imperative to delve into the global trends of incidence and death rate for multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB), drawing upon the comprehensive Global Burden of Disease (GBD) 2021 drug-resistant tuberculosis dataset.</p></div><div><h3>Methods</h3><p>From the GBD 2021, data on incidence, prevalence, disability-adjusted life years (DALYs), and death of MDR-TB and XDR-TB from 1990 to 2021 were collected. We calculated the estimated annual percentage changes in age standardized incidence rate (ASIR) and age-standardized death rate (ASDR), segmented by age, sex, and Socio-demographic Index (SDI). The impacts of various risk factors on MDR-TB and XDR-TB were also analyzed.</p></div><div><h3>Results</h3><p>In 2021, there were an estimated 443,680 (95% uncertainty interval [<em>UI</em>]: 259,196–766,545) incident cases of MDR-TB, and an estimated 106,818 (95% <em>UI</em>: 41,612–211,854) death cases of MDR-TB, while there were an estimated 24,036 (95% <em>UI</em>: 17,144–34,587) incident cases of XDR-TB and 7,946 (95% <em>UI</em>: 3,326–14,859) death cases of XDR-TB. The incidence and death cases of MDR-TB were lowest in high SDI regions, whereas the incidence rates of XDR-TB in high-middle SDI regions were higher than those in middle SDI and high SDI regions.</p></div><div><h3>Conclusion</h3><p>This study reported the disease burden of drug-resistant TB from 1990 to 2021. Until 2021, drug-resistant TB is still a serious problem in low SDI countries, especially for high-risk age populations with high-risk factors. Controlling drug-resistant TB requires effective control strategies and healthcare systems.</p></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"3 ","pages":"Article 100072"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949704324000118/pdfft?md5=521aef4f703bbd32d1a1bd9b547f2d92&pid=1-s2.0-S2949704324000118-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary exposure assessment of perchlorate and chlorate in infant formulas marketed in Shanghai, China","authors":"Shenghao Yu ,&nbsp;Yonghui Ge ,&nbsp;Lujing Zhang ,&nbsp;Yiqi Li ,&nbsp;Wen Zhang ,&nbsp;Chang Liu ,&nbsp;Shaojie Peng","doi":"10.1016/j.soh.2024.100062","DOIUrl":"10.1016/j.soh.2024.100062","url":null,"abstract":"<div><p>Perchlorate and chlorate are ubiquitous pollutants that can adversely affect the thyroid function in humans. This study assessed the potential health risks associated with the dietary exposure of infants and young children to perchlorate and chlorate present in infant formulas available in Shanghai. The assessment was based on risk monitoring data from 150 samples of infant formulas in Shanghai between 2020 and 2022, along with the dietary consumption data of infants and young children. The detection rates of perchlorate and chlorate in infant formulas were 46.0% and 98.7%, with mean contents of 9.98 μg/kg and 112.01 μg/kg, and the maximum values of 151.00 μg/kg and 1475.00 μg/kg, respectively. The mean and 95th percentile (<em>P</em>₉₅) values of daily perchlorate exposure of 0–36-month-old infant and young children via infant formulas were 0.07 and 0.17 μg/kg body weight (bw) per day, respectively, which were lower than the tolerable daily intake (TDI) of perchlorate (0.3 μg/kg bw per day). The mean and <em>P</em>₉₅ values of chlorate exposure via infant formulas in 0–36-month-old infants and young children were 0.83 and 1.89 μg/kg bw per day, which were lower than the TDI of chlorate (3 μg/kg bw per day). The <em>P</em>₉₅ exposure of different age groups (0–6 months, 7–12 months and 13–36 months) of infants and young children to perchlorate and chlorate in infant formulas was below the TDI. Therefore, the risk associated with the exposure of 0–36-month-old infants and young children to perchlorate and chlorate from infant formulas in Shanghai is considered acceptable. Prioritizing environmental pollution control efforts to reduce the levels of perchlorate and chlorate in food products is important to safeguard the health of the infants and children under the One Health concept.</p></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"3 ","pages":"Article 100062"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949704324000015/pdfft?md5=23155952d0e7b28f4b7a19e3fd32b52f&pid=1-s2.0-S2949704324000015-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139634859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing Chagas disease from a One Health perspective: risk factors, lessons learned and prevention of oral transmission outbreaks in Colombia","authors":"Mario J. Olivera ,&nbsp;Claudia Yaneth Rincón Acevedo ,&nbsp;Antonio José Olivera ,&nbsp;Sergio Mendez-Cardona ,&nbsp;Mauricio Javier Vera Soto","doi":"10.1016/j.soh.2024.100066","DOIUrl":"10.1016/j.soh.2024.100066","url":null,"abstract":"<div><h3>Background</h3><p>Chagas disease (CD) is transmitted by vectors but can also be transmitted orally through contaminated food, drinks, or meat. The One Health perspective aims to understand the complex interaction between human, animal, and environmental health in controlling disease. This study analyzed risk factors and drew lessons from past outbreaks of orally transmitted CD to develop effective preventive strategies.</p></div><div><h3>Methods</h3><p>A simultaneous mixed methods study was conducted. The study consisted of two phases: an ecological epidemiological analysis at the municipal level using secondary data spanning from 1992 to 2023, and semistructured interviews with health providers and policymakers at the national level in Colombia. The results from both phases were triangulated to gain a comprehensive understanding of the topic.</p></div><div><h3>Results</h3><p>A total of 64 outbreaks, infecting 302 individuals, were reported. Most of these outbreaks (89.2%) were classified as family-related, and they occurred most frequently during the months of April to June (46.6%). It is worth noting that a significant number of these outbreaks took place in municipalities that lacked vector control plans. Risk factors for oral transmission included the location of food preparation, poor housing quality, food preparation water source, the presence of vectors/marsupials, forest type, and climatic variables. Interviews conducted emphasized the importance of implementing outbreak plans and providing staff training to effectively address the issue.</p></div><div><h3>Conclusion</h3><p>A One Health approach strengthening prevention, surveillance, case management and cross-sectoral collaboration is needed to control outbreaks and reduce transmission in Colombia. Preparedness plans and education of health professionals are also important. This study identified modifiable risk factors to guide public health interventions.</p></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"3 ","pages":"Article 100066"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949704324000052/pdfft?md5=1b9a4cf54660df97b5db10200ddcbf67&pid=1-s2.0-S2949704324000052-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140773076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}