RSC Mechanochemistry最新文献_第3页

Force-driven architectonics of inorganic nanomaterials: pathways to smart and functional interfaces 无机纳米材料的力驱动架构：通往智能和功能界面的途径

RSC Mechanochemistry Pub Date : 2026-01-07 DOI: 10.1039/D5MR00116A

Mohammed Ali Dheyab, Wesam Abdullah, Sara Abdulwahab, Sadeen Metib Alsarayreh, Mothana Hussein Tarawneh, Mutaz Mohammad Alsardi, Mansour A. Alanazi and Azlan Abdul Aziz

{"title":"Force-driven architectonics of inorganic nanomaterials: pathways to smart and functional interfaces","authors":"Mohammed Ali Dheyab, Wesam Abdullah, Sara Abdulwahab, Sadeen Metib Alsarayreh, Mothana Hussein Tarawneh, Mutaz Mohammad Alsardi, Mansour A. Alanazi and Azlan Abdul Aziz","doi":"10.1039/D5MR00116A","DOIUrl":"https://doi.org/10.1039/D5MR00116A","url":null,"abstract":"The deliberate structuring of inorganic nanomaterials through mechanical forces offers a powerful alternative to conventional synthesis, enabling solvent-free, energy-efficient, and scalable design strategies. Rather than serving only as a synthetic shortcut, force-driven processing is increasingly recognized as an architectonic tool as a means of directing matter into well-defined architectures that integrate top-down shaping with bottom-up assembly. This review develops a conceptual framework of architectonics under mechanical activation, treating external force as a design parameter that dictates structure formation across multiple length scales. Methodological platforms such as ball milling, extrusion, and hybrid force–stimuli systems are systematically assessed, alongside mechanistic insights spanning multiscale reaction pathways, computational modeling, and AI-enabled predictions. The potential of this approach to generate smart and functional interfaces is highlighted through applications in catalytic and energy conversion processes, biomedical nanomedicine, and electronic or sensing devices. Finally, we discuss current limitations particularly gaps in mechanistic understanding, predictive control, and scalability and outline future opportunities to advance force-driven architectonics as a foundation for next-generation functional inorganic nanomaterials.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 161-190"},"PeriodicalIF":0.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00116a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-throughput C–H activation in a bead-beater homogenizer: fast and regioselective access to 2-arylindoles 高通量C-H活化在头部加热均质机：快速和区域选择性访问2-芳基吲哚

RSC Mechanochemistry Pub Date : 2026-01-07 DOI: 10.1039/D5MR00124B

Mainak Banerjee, Shravya B., Aboy Chatterjee, Shamima Hussain and Amtita Chatterjee

{"title":"High-throughput C–H activation in a bead-beater homogenizer: fast and regioselective access to 2-arylindoles","authors":"Mainak Banerjee, Shravya B., Aboy Chatterjee, Shamima Hussain and Amtita Chatterjee","doi":"10.1039/D5MR00124B","DOIUrl":"https://doi.org/10.1039/D5MR00124B","url":null,"abstract":"High-throughput mechanochemical synthesis is rarely attempted. A bead-beater homogenizer with 24–64 slots offers a unique opportunity for high-throughput mechanosynthesis (HTMS). In this study, C–H bond activation is achieved by homogenizing multiple samples in one go in simple polypropylene (PP) vials with stainless steel balls via liquid-assisted grinding (LAG), with enough frictional force being employed to achieve this challenging transformation. The method demonstrates the preparation of synthetically useful 2-arylindoles through a regioselective reaction between N-alkylated indoles and aryl iodides, catalyzed by Pd(II) and facilitated by C2–H activation in the absence of phosphine ligands, using a bead-beater homogenizer. 5 mol% of Pd(OAc)2 was sufficient to catalyze C2-activation of indoles in the presence of a small volume of EtOAc as the LAG agent, affording 2-arylindoles in high to excellent yields within 9 min. The method demonstrated excellent tolerance to structural variations, including electron-rich and electron-deficient substituents in both indoles and iodoarenes. However, unprotected indoles or indoles with deactivated five-membered rings could not participate well in the reaction. This simple, high-yielding, ambient-temperature high-throughput mechanochemical protocol is devoid of a formal workup step, and with a low E-factor (4.5) and a high Eco-scale score (73.5), it augments well with sustainability matrices.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 309-315"},"PeriodicalIF":0.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00124b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ab initio force prediction for single molecule force spectroscopy made simple 单分子力谱的从头算力预测变得简单

RSC Mechanochemistry Pub Date : 2026-01-07 DOI: 10.1039/D5MR00129C

Pooja Bhat, Wafa Maftuhin and Michael Walter

引用次数: 0

Mechanochemical synthesis of bent metallacycles and confinement catalysis in the solid-state 弯曲金属环的机械化学合成及固相约束催化

RSC Mechanochemistry Pub Date : 2025-12-23 DOI: 10.1039/D5MR00075K

Peiyi Wang, Shi Li, Fang-Zi Liu and KaKing Yan

引用次数: 0

Sustainable mechanochemical synthesis of functionalisable fluorinated scaffolds for drug discovery using green LAG 利用绿色LAG可持续机械化学合成可功能化的氟化支架用于药物发现

RSC Mechanochemistry Pub Date : 2025-12-18 DOI: 10.1039/D5MR00100E

Adam G. Buchanan, Elizabeth T. Areola, Maryam Farrukh Butt, Yan Kiu Lee, Jasper Murphy, Annie E. Taylor, Avninder S. Bhambra and George W. Weaver

{"title":"Sustainable mechanochemical synthesis of functionalisable fluorinated scaffolds for drug discovery using green LAG","authors":"Adam G. Buchanan, Elizabeth T. Areola, Maryam Farrukh Butt, Yan Kiu Lee, Jasper Murphy, Annie E. Taylor, Avninder S. Bhambra and George W. Weaver","doi":"10.1039/D5MR00100E","DOIUrl":"https://doi.org/10.1039/D5MR00100E","url":null,"abstract":"Fluoroarenes have become widely recognised as useful building blocks in medicinal chemistry, and manipulation of these compounds can be achieved readily using nucleophilic aromatic substitution (SNAr) to introduce a diverse range of functionality for drug development. A more sustainable mechanochemical approach to SNAr of fluoroarenes using planetary ball milling with a range of aliphatic and aromatic amines as nucleophiles has been investigated with 20 examples described. An efficient set of milling conditions using liquid assisted grinding (LAG) employing the bio-solvent Cyrene or water, and short reaction times (30 minutes) has been developed. Yields were consistently higher when using Cyrene or water as LAG agent rather than DMF. The method provides a useful alternative to the dipolar aprotic solvents DMF and DMSO and high temperatures commonly used in SNAr. Ethyl acetate is employed in the extractive work-up, but is recyclable and considered a green solvent. The method reduces or obviates bulk reaction solvent and aqueous waste streams containing dipolar aprotic solvents.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 265-272"},"PeriodicalIF":0.0,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00100e?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highlights from the Mech'cheM 2025 conference: New forces in Mechanochemistry, Montpellier, France, June 4-6, 2025 Mech'cheM 2025会议亮点：机械化学的新力量，法国蒙彼利埃，2025年6月4-6日

RSC Mechanochemistry Pub Date : 2025-12-18 DOI: 10.1039/D5MR90034D

Xavier Bantreil, Olivia Giani, Laure Monconduit, Nicolas Pétry, Julien Pinaud, Béatrice Roy and Frédéric Lamaty

引用次数: 0

Relationships between milling input energy and chemical reactivity for mechanochemical activation of clays 粘土机械化学活化的研磨输入能量与化学反应性的关系

RSC Mechanochemistry Pub Date : 2025-12-17 DOI: 10.1039/D5MR00088B

Alastair T. M. Marsh, Sreejith Krishnan, Suraj Rahmon, Susan A. Bernal and Xinyuan Ke

{"title":"Relationships between milling input energy and chemical reactivity for mechanochemical activation of clays","authors":"Alastair T. M. Marsh, Sreejith Krishnan, Suraj Rahmon, Susan A. Bernal and Xinyuan Ke","doi":"10.1039/D5MR00088B","DOIUrl":"https://doi.org/10.1039/D5MR00088B","url":null,"abstract":"Mechano-chemical activation is of rapidly growing interest for producing cementitious constituents from clays. The chemical reactivity of clay minerals is enhanced during intensive grinding, due to mechano-chemical dehydroxylation and mechanically-induced amorphisation. The most widely used grinding apparatus for laboratory-scale studies is a planetary ball mill. It is still largely unknown whether activation efficacy is critically dependent on any individual milling parameter, or whether trade-offs are possible between different parameters. In this study a first principles approach, previously applied to alloy amorphisation, is adopted to estimate the energy of an individual collision event and the total milling input energy. Using a combination of primary data generated through experiments and secondary data from literature, a set of nearly 100 datapoints was analysed. Rapid increases in chemical reactivity were generally observed for <100 kJ g−1 of modelled milling energy input, with a plateau beyond this value. The relationship between chemical reactivity and modelled energy input was well fitted by an exponential type function. For the same modelled milling energy input, a higher gain in chemical reactivity was achieved for the 1 : 1 clay minerals compared to the 2 : 1 clay minerals or mixtures of different clay minerals. No strong trends were observed with individual collision energy, with no clear evidence for the existence of a threshold collision energy. The modelled milling input energy was more effective for predicting reactivity increase than measured energy consumption by the mill. Within the ranges tested, increasing ball : powder ratio or rotation speed seemed to be more energetically efficient at increasing reactivity, compared to increasing milling duration. Results from this study can also aid in selection of milling equipment for scaling up this process.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 201-212"},"PeriodicalIF":0.0,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00088b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rock tumbler for mechanochemistry: generation of a photoactive cocrystal and a metal–organic framework 机械化学用岩石搅拌器：光活性共晶和金属有机骨架的生成

RSC Mechanochemistry Pub Date : 2025-12-16 DOI: 10.1039/D5MR00108K

Christopher Hartwick, Karah A. Putnam, Alexios K. Plessas, Akalanka B. Ekanayake, Cherolyn K. Henke, Michael A. Sinnwell, Alexei V. Tivanski and Leonard R. MacGillivray

引用次数: 0

Mechanistic investigation of the mechanochemical reduction of LiCoO2 with Al in the context of lithium-ion battery recycling 锂离子电池回收背景下Al机械化学还原LiCoO2的机理研究

RSC Mechanochemistry Pub Date : 2025-12-15 DOI: 10.1039/D5MR00092K

Raphael Sieweck, Arseniy Bokov, Oleksandr Dolotko, Thomas Bergfeldt, Udo Geckle, Michael Knapp and Helmut Ehrenberg

{"title":"Mechanistic investigation of the mechanochemical reduction of LiCoO2 with Al in the context of lithium-ion battery recycling","authors":"Raphael Sieweck, Arseniy Bokov, Oleksandr Dolotko, Thomas Bergfeldt, Udo Geckle, Michael Knapp and Helmut Ehrenberg","doi":"10.1039/D5MR00092K","DOIUrl":"https://doi.org/10.1039/D5MR00092K","url":null,"abstract":"Lithium-ion batteries are the most common energy storage system for consumer electronics and electric vehicles, and are now emerging into the market for stationary applications. However, their production depends on critical raw materials, such as lithium, nickel, and cobalt. When reaching the end of their life, spent batteries are regarded as toxic waste, underscoring the need for efficient and inexpensive recycling technologies to enable a circular economy. Current recycling technologies exhibit issues, such as wastewater generation and high consumption of energy and chemicals. While the focus has been on the recovery of valuable transition metals, lithium is often not recovered. In this study, we present a deeper investigation of the solvent-free mechanochemical reduction of LiCoO2 with Al. The combined analysis using XRD, SEM and EDX, together with the observation of a characteristic temperature and pressure profile, proved the reaction to proceed via a mechanically induced self-propagating reaction pathway. A spike in the pressure, detected by an internal sensor in the milling jar, was used to determine the length of the activation phase, which enables a kinematic analysis and the systematic study of milling parameters. Furthermore, the presence of graphite was found to increase the activation time and with a 20% weight fraction, the self-propagating behavior can be suppressed. This research provides important information regarding the application of this process on a real black mass or on a larger scale.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 243-253"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00092k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Moving mechanochemistry forward: accelerating and tuning organic synthesis by mechanochemistry 推动机械化学前进：利用机械化学加速和调整有机合成

RSC Mechanochemistry Pub Date : 2025-12-15 DOI: 10.1039/D5MR90035B

Isaiah R. Speight and James Mack

引用次数: 0