RSC Mechanochemistry最新文献

Moving mechanochemistry forward: mechanocatalysis 推动机械化学向前发展：机械催化

RSC Mechanochemistry Pub Date : 2026-03-02 DOI: 10.1039/D6MR90005D

Ferdi Schüth and Claudia Weidenthaler

引用次数: 0

Amorphous-to-crystalline transformation: a mechanochemical pathway to imine-linked covalent organic frameworks. 无定形到结晶的转变：一个机械化学途径到亚胺连接的共价有机框架。

RSC Mechanochemistry Pub Date : 2026-01-29 DOI: 10.1039/d5mr00161g

Normanda Brown, Yogendra Nailwal, Tyra Blair, Ziad Alsudairy, Qingsong Zhang, Krystal Kennedy, Yi Liu, Xinle Li

{"title":"Amorphous-to-crystalline transformation: a mechanochemical pathway to imine-linked covalent organic frameworks.","authors":"Normanda Brown, Yogendra Nailwal, Tyra Blair, Ziad Alsudairy, Qingsong Zhang, Krystal Kennedy, Yi Liu, Xinle Li","doi":"10.1039/d5mr00161g","DOIUrl":"10.1039/d5mr00161g","url":null,"abstract":"Amorphous-to-crystalline transformation is of profound importance in the crystallization of covalent organic frameworks (COFs), yet its potential through solid-state mechanochemistry remains largely unexplored. Here, we introduce a mechanochemical amorphous-to-crystalline pathway to synthesize imine-linked COFs under ambient conditions. By ball milling their amorphous progenitors, nine imine-linked COFs with distinct core structures, topologies (hcb, sql, kgm, and dia), and dimensions are constructed in as little as one hour. Notably, the unique advantage of this method is highlighted by the successful synthesis of a highly crystalline, porous pyrene-based COF inaccessible by de novo mechanosynthesis. A mechanochemical \"scrambling\" reaction of imine-based model compounds confirms the high reversibility of the imine bonds in the solid state, which is crucial for facilitating error correction during COF reconstruction. This study underscores mechanochemistry as an effective means for amorphous-to-crystalline transformation, establishing a facile, generic, and green pathway to imine-linked COFs, including those unattainable via conventional de novo mechanosynthesis.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12869355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146128393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of ball mass, surface, and contact dynamics in mechanochemical reactions. 球质量、表面和接触动力学在机械化学反应中的作用。

RSC Mechanochemistry Pub Date : 2026-01-28 DOI: 10.1039/d5mr00146c

Marisol F Rappen, Justus Mäder, Tino Schwemin, Sven Grätz, Lars Borchardt

引用次数: 0

When chirality breaks: mechanochemical degradation of biaryl atropisomers 手性断裂时：联芳基反二聚体的机械化学降解

RSC Mechanochemistry Pub Date : 2026-01-27 DOI: 10.1039/D5MR00132C

Leon Poljanić, Tom Leyssens, Laurent Collard and Daniel M. Baier

引用次数: 0

Selective mechanochemical conversion of post-consumer polyethylene terephthalate waste into hcp and fcu UiO-66 metal–organic frameworks† 消费后聚对苯二甲酸乙二醇酯废物选择性机械化学转化成hcp和fcu UiO-66金属有机骨架

RSC Mechanochemistry Pub Date : 2026-01-08 DOI: 10.1039/D4MR00126E

Tomislav Stolar, Dilara Bayram, Anastasia May, Remie Sundermann, Carsten Prinz, Klas Meyer, Anett Myxa, Jana Falkenhagen and Franziska Emmerling

引用次数: 0

Force-driven architectonics of inorganic nanomaterials: pathways to smart and functional interfaces 无机纳米材料的力驱动架构：通往智能和功能界面的途径

RSC Mechanochemistry Pub Date : 2026-01-07 DOI: 10.1039/D5MR00116A

Mohammed Ali Dheyab, Wesam Abdullah, Sara Abdulwahab, Sadeen Metib Alsarayreh, Mothana Hussein Tarawneh, Mutaz Mohammad Alsardi, Mansour A. Alanazi and Azlan Abdul Aziz

{"title":"Force-driven architectonics of inorganic nanomaterials: pathways to smart and functional interfaces","authors":"Mohammed Ali Dheyab, Wesam Abdullah, Sara Abdulwahab, Sadeen Metib Alsarayreh, Mothana Hussein Tarawneh, Mutaz Mohammad Alsardi, Mansour A. Alanazi and Azlan Abdul Aziz","doi":"10.1039/D5MR00116A","DOIUrl":"https://doi.org/10.1039/D5MR00116A","url":null,"abstract":"The deliberate structuring of inorganic nanomaterials through mechanical forces offers a powerful alternative to conventional synthesis, enabling solvent-free, energy-efficient, and scalable design strategies. Rather than serving only as a synthetic shortcut, force-driven processing is increasingly recognized as an architectonic tool as a means of directing matter into well-defined architectures that integrate top-down shaping with bottom-up assembly. This review develops a conceptual framework of architectonics under mechanical activation, treating external force as a design parameter that dictates structure formation across multiple length scales. Methodological platforms such as ball milling, extrusion, and hybrid force–stimuli systems are systematically assessed, alongside mechanistic insights spanning multiscale reaction pathways, computational modeling, and AI-enabled predictions. The potential of this approach to generate smart and functional interfaces is highlighted through applications in catalytic and energy conversion processes, biomedical nanomedicine, and electronic or sensing devices. Finally, we discuss current limitations particularly gaps in mechanistic understanding, predictive control, and scalability and outline future opportunities to advance force-driven architectonics as a foundation for next-generation functional inorganic nanomaterials.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 161-190"},"PeriodicalIF":0.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00116a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-throughput C–H activation in a bead-beater homogenizer: fast and regioselective access to 2-arylindoles 高通量C-H活化在头部加热均质机：快速和区域选择性访问2-芳基吲哚

RSC Mechanochemistry Pub Date : 2026-01-07 DOI: 10.1039/D5MR00124B

Mainak Banerjee, Shravya B., Aboy Chatterjee, Shamima Hussain and Amtita Chatterjee

{"title":"High-throughput C–H activation in a bead-beater homogenizer: fast and regioselective access to 2-arylindoles","authors":"Mainak Banerjee, Shravya B., Aboy Chatterjee, Shamima Hussain and Amtita Chatterjee","doi":"10.1039/D5MR00124B","DOIUrl":"https://doi.org/10.1039/D5MR00124B","url":null,"abstract":"High-throughput mechanochemical synthesis is rarely attempted. A bead-beater homogenizer with 24–64 slots offers a unique opportunity for high-throughput mechanosynthesis (HTMS). In this study, C–H bond activation is achieved by homogenizing multiple samples in one go in simple polypropylene (PP) vials with stainless steel balls via liquid-assisted grinding (LAG), with enough frictional force being employed to achieve this challenging transformation. The method demonstrates the preparation of synthetically useful 2-arylindoles through a regioselective reaction between N-alkylated indoles and aryl iodides, catalyzed by Pd(II) and facilitated by C2–H activation in the absence of phosphine ligands, using a bead-beater homogenizer. 5 mol% of Pd(OAc)2 was sufficient to catalyze C2-activation of indoles in the presence of a small volume of EtOAc as the LAG agent, affording 2-arylindoles in high to excellent yields within 9 min. The method demonstrated excellent tolerance to structural variations, including electron-rich and electron-deficient substituents in both indoles and iodoarenes. However, unprotected indoles or indoles with deactivated five-membered rings could not participate well in the reaction. This simple, high-yielding, ambient-temperature high-throughput mechanochemical protocol is devoid of a formal workup step, and with a low E-factor (4.5) and a high Eco-scale score (73.5), it augments well with sustainability matrices.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 309-315"},"PeriodicalIF":0.0,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00124b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ab initio force prediction for single molecule force spectroscopy made simple 单分子力谱的从头算力预测变得简单

RSC Mechanochemistry Pub Date : 2026-01-07 DOI: 10.1039/D5MR00129C

Pooja Bhat, Wafa Maftuhin and Michael Walter

引用次数: 0

Mechanochemical synthesis of bent metallacycles and confinement catalysis in the solid-state 弯曲金属环的机械化学合成及固相约束催化

RSC Mechanochemistry Pub Date : 2025-12-23 DOI: 10.1039/D5MR00075K

Peiyi Wang, Shi Li, Fang-Zi Liu and KaKing Yan

引用次数: 0

Sustainable mechanochemical synthesis of functionalisable fluorinated scaffolds for drug discovery using green LAG 利用绿色LAG可持续机械化学合成可功能化的氟化支架用于药物发现

RSC Mechanochemistry Pub Date : 2025-12-18 DOI: 10.1039/D5MR00100E

Adam G. Buchanan, Elizabeth T. Areola, Maryam Farrukh Butt, Yan Kiu Lee, Jasper Murphy, Annie E. Taylor, Avninder S. Bhambra and George W. Weaver

{"title":"Sustainable mechanochemical synthesis of functionalisable fluorinated scaffolds for drug discovery using green LAG","authors":"Adam G. Buchanan, Elizabeth T. Areola, Maryam Farrukh Butt, Yan Kiu Lee, Jasper Murphy, Annie E. Taylor, Avninder S. Bhambra and George W. Weaver","doi":"10.1039/D5MR00100E","DOIUrl":"https://doi.org/10.1039/D5MR00100E","url":null,"abstract":"Fluoroarenes have become widely recognised as useful building blocks in medicinal chemistry, and manipulation of these compounds can be achieved readily using nucleophilic aromatic substitution (SNAr) to introduce a diverse range of functionality for drug development. A more sustainable mechanochemical approach to SNAr of fluoroarenes using planetary ball milling with a range of aliphatic and aromatic amines as nucleophiles has been investigated with 20 examples described. An efficient set of milling conditions using liquid assisted grinding (LAG) employing the bio-solvent Cyrene or water, and short reaction times (30 minutes) has been developed. Yields were consistently higher when using Cyrene or water as LAG agent rather than DMF. The method provides a useful alternative to the dipolar aprotic solvents DMF and DMSO and high temperatures commonly used in SNAr. Ethyl acetate is employed in the extractive work-up, but is recyclable and considered a green solvent. The method reduces or obviates bulk reaction solvent and aqueous waste streams containing dipolar aprotic solvents.","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":" 2","pages":" 265-272"},"PeriodicalIF":0.0,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2026/mr/d5mr00100e?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0