中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.016
Jian Tian, Yingqiang Li, Lei Wang, Jianing Xiong, Cui-Jie Gong
{"title":"Endovascular treatment of multiple intracranial aneurysms with severe coronary heart disease: one case report","authors":"Jian Tian, Yingqiang Li, Lei Wang, Jianing Xiong, Cui-Jie Gong","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.016","url":null,"abstract":"","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"9 1","pages":"1161-1163"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81090069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.021
Wentao Zheng
{"title":"Recent advance in treatment of Meige syndrome","authors":"Wentao Zheng","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.021","url":null,"abstract":"Meige syndrome is a rare segmental craniocervical dystonia, mainly characterized by blepharospasm and involuntary contraction of jaw and neck muscles, which will seriously decrease the patient's quality of life. The etiology and pathogenesis of the disease remain unclear, despite of some progress having been made in the relevant studies. Current treatments include drug therapy, botulinum toxin A injection and surgical treatment. In this article, the pathogenesis, clinical manifestations and treatment of Meige syndrome will be briefly reviewed. \u0000 \u0000 \u0000Key words: \u0000Meige syndrome; Dystonia; Botulinum toxin; Deep brain stimulation","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"35 1","pages":"1180-1183"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81335691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.008
Weiwei Li, Huimian Li
{"title":"Correlations of serum level of thyroid-stimulating hormone with tumor necrosis factor-α, lipoprotein associated phospholipase A2 and interleukine-6 levels in ischemic stroke patients with subclinical hypothyroidism","authors":"Weiwei Li, Huimian Li","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.008","url":null,"abstract":"Objective \u0000To evaluate the correlations of serum level of thyroid-stimulating hormone (TSH) with levels of inflammatory factors lipoprotein associated phospholipase A2 (Lp-PLA2), tumor necrosis factor-α (TNF-α) and interleukine (IL)-6 in ischemic stroke (IS) patients with subclinical hypothyroidism (SCH) and its clinical significance. \u0000 \u0000 \u0000Methods \u0000Twenty SCH patients, 30 IS patients and 30 IS+SCH patients, admitted to our hospital from October 2017 to October 2018, were enrolled in our study; 27 subjects underwent physical examination in our hospital at the same period were selected as the control group. The serum levels of TSH, Lp-PLA2, TNF-α and IL-6 were measured by up-converting phoshor assay and enzyme - linked immunosorbent assay with double antibody sandwich. The common carotid artery, internal carotid artery and vertebral artery were examined by Doppler ultrasonography to analyze the morphology, location, and echo characteristics of the plaques and stenosis rates. Pearson correlation analysis was used to analyze the correlations of TSH with inflammatory factors, carotid artery stenosis rate. \u0000 \u0000 \u0000Results \u0000The levels of Lp-PLA2, TNF-α and IL-6 in IS+SCH group were significantly higher than those in SCH group, IS group and control group (P<0.05); those in the SCH group and IS group were significantly higher than those in the control group (P<0.05). The serum TSH levels in IS+SCH group and SCH group were positively correlated with Lp-PLA2 level (r=0.739, P=0.000; r= 0.697, P=0.000), TNF-α level (r=0.981, P=0.000; r=0.723, P=0.000) and IL-6 level (r=0.859, P=0.000; r=0.583, P=0.000); but the serum TSH levels in IS group and NC group were not correlated with Lp-PLA2 level (r=0.223, P=0.236; r=0.249, P=0.210), TNF-α level (r=0.304, P=0.103; r=0.056, P=0.780) and IL-6 level (r=0.027, P=0.887; r=0.138, P=0.491). The number of unstable plaques and degree of stenosis in IS+SCH group were larger/higher than those in IS group, SCH group and control group (P< 0.05); there was a positive correlation between serum TSH level and artery stenosis rate (r=0.739, P= 0.000). \u0000 \u0000 \u0000Conclusion \u0000SCH may lead to occurrence and development of atherosclerosis by increasing the serum levels of TNF-α, Lp-PLA2 and IL-6 caused by low-level chronic inflammation, which in turn increases the risk of ischemic stroke. \u0000 \u0000 \u0000Key words: \u0000Ischemic stroke; Subclinical hypothyroidism; Thyroid-stimulating hormone; Lipoprotein associated phospholipase A2; Tumor necrosis factor-α; Interleukin-6","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"22 1","pages":"1124-1130"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73806625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.020
Guoxian Sun, Weili Liu, A. Sun, Hongling Hou
{"title":"Recent advance in aggressive behavior induced by antiepileptic drugs","authors":"Guoxian Sun, Weili Liu, A. Sun, Hongling Hou","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.020","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.020","url":null,"abstract":"Antiepileptic drugs (AEDs) are the main treatments for epilepsy. Patients with epilepsy will benefit a lot from AEDs. However, AEDs also have a variety of adverse drug effects, including aggressive behavior (AB). It will have important clinical significance of identifying and treating correctly AB since of its dangers, caused by AEDs. This article will review the clinical features, susceptibility factors and mechanisms of AB induced by AEDs. \u0000 \u0000 \u0000Key words: \u0000Antiepileptic drug; Aggressive behavior; Mechanism","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"34 1","pages":"1177-1179"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88436737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.010
Yang Liu, P. Jiang, Jia Yang, Shanshan Wang, B. Wang, Jianxiong Liu
{"title":"Establishment of prognosis prediction scale for aspirin combined with clopidogrel in acute cerebral infarction and preliminary evaluation of its prediction effectiveness","authors":"Yang Liu, P. Jiang, Jia Yang, Shanshan Wang, B. Wang, Jianxiong Liu","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.010","url":null,"abstract":"Objective \u0000To establish a prognosis prediction scale for aspirin combined with clopidogrel in treatment of acute cerebral infarction (ACI) and evaluate its prediction effectiveness. \u0000 \u0000 \u0000Methods \u0000A retrospective analysis of clinical features of 202 ACI patients, admitted to and accepted aspirin combined with clopidogrel in our hospital from October 2017 to April 2019, was performed. According to the differences of National Institutes of Health Stroke Scale (NIHSS) scores before and after treatment, the patients were divided into good prognosis group and poor prognosis group; univariate and multivariate Logistic regression analyses were used to screen the independent risk factors for prognoses of acute cerebral infarction; assignment of these factors was performed, respectively, to establish prediction scale; and finally the prediction scale was applied to the patients for verification. \u0000 \u0000 \u0000Results \u0000Of the 202 patients, 167 had a good prognosis and 35 had a poor prognosis. Multivariate Logistic regression analysis revealed that age≥50 years, hypertension, homocysteine, and carotid stenosis≥50% were independent risk factors for prognoses 14 d after onset in patients with ACI (P< 0.05); the assigned values of age≥50 years, hypertension grading I, hypertension grading II, hypertension grading III, homocysteine, and carotid stenosis≥50% were 1, 1, 2, 3, 1, and 1, respectively; the total pridiction scale scores were 0-6. Validation results showed that the poor prognosis rate of patients with predictive scale scores≥3 was 91.3% (157/172) and that of patients with predictive scale scores<3 was 33.3% (10/30). \u0000 \u0000 \u0000Conclusion \u0000The predictive scale established in this study can be used to quickly and accurately identify patients with acute cerebral infarction who are suitable for aspirin combined with clopidogrel. \u0000 \u0000 \u0000Key words: \u0000Cerebral infarction; Aspirin combined with clopidogrel; Prognosis; Prediction scale; Influencing factor","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"9 1","pages":"1136-1141"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88440939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.003
J. Hao, Meng Zhang, Chao Liu, Zidong Wang, Wei-dong Liu, Kai Lin, Jiyue Wang
{"title":"Hybrid surgery for chronic symptomatic occlusion of the internal carotid artery: an analysis of 9 cases","authors":"J. Hao, Meng Zhang, Chao Liu, Zidong Wang, Wei-dong Liu, Kai Lin, Jiyue Wang","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.003","url":null,"abstract":"Objective \u0000To investigate the feasibility and safety of hybrid surgery in treatment of chronic symptomatic internal carotid artery occlusion. \u0000 \u0000 \u0000Methods \u0000From April 2016 to December 2018, 9 patients with chronic symptomatic internal carotid artery occlusion confirmed by digital subtraction angiography were treated with carotid endarterectomy (CEA)+ double chamber Fogarty balloon (3F) embolectomy or stent implantation when necessary. The clinical data of these patients were retrospectively analyzed. Vascular recanalization and complications during perioperative period and follow-up of the patients were analyzed. \u0000 \u0000 \u0000Results \u0000CEA+double chamber Fogarty balloon (3F) thrombectomy was performed in 5 patients; and stent placement was performed in 4 patients after Fogarty balloon thrombectomy. The internal carotid arteries of all 9 patients were unobstructed immediately during the operation. Postoperative hyperperfusion syndrome occurred in 3 patients; blood pressure was strictly controlled and the symptoms gradually relieved after proper dehydration. No serious complications such as cerebral hemorrhage, cerebral infarction, or nerve injury occurred. The duration of follow-up was 4-36 months; no patient developed a new stroke or death; no re-occlusion appeared; but one mild restenosis (50%) was detected. one patient suffered from a TIA attack 6 months after operation. \u0000 \u0000 \u0000Conclusion \u0000Hybrid surgery is an effective method for treatment of chronic symptomatic internal carotid artery occlusion; however, preoperative evaluation and selection of patients should be carefully; individualized treatment plans should be developed. \u0000 \u0000 \u0000Key words: \u0000Internal carotid artery occlusion; Hybrid surgery; Endarterectomy; Fogarty catheter embolectomy; Carotid artery stenting","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"92 1","pages":"1091-1097"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89134845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.011
Guoyong Ren, P. Xue, Ying-Jun Mi, Long Zhang
{"title":"Effect of statin pretreatment on collateral circulation and prognoses of patients with cardiac large artery occlusive stroke","authors":"Guoyong Ren, P. Xue, Ying-Jun Mi, Long Zhang","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.011","url":null,"abstract":"Objective \u0000To investigate the effect of statin pretreatment on collateral circulation and prognoses of patients with cardiac large artery occlusive stroke. \u0000 \u0000 \u0000Methods \u0000Fifty-three patients with cardiac large artery occlusive stroke admitted to our hospital from January 2016 to July 2019 were selected. All patients had unilateral middle cerebral artery occlusion. DSA was used to evaluate the collateral flows, and the differences of collateral flows and prognoses in patients took statins before onset were compared with those did not take statins. \u0000 \u0000 \u0000Results \u0000As compared with patients did not take statins, patients took statins had higher incidences of diabetes and coronary heart disease, lower content of low density cholesterol, higher proportion of patients with good collateral circulation (grading 3 to 4), and lower modified Rankin scale scores 3 months after surgery, with statistically significant differences (P< 0.05). Multivariate Logistic regression analysis showed that percentage of patients took statins was independent factors affecting collateral flow in patients with cardiac arterial occlusive stroke(OR=5.000, 95%CI: 1.136-22.006, P=0.033). \u0000 \u0000 \u0000Conclusion \u0000In patients with cardiac large artery occlusive stroke, statin pretreatment could improve collateral flow and clinical prognoses. \u0000 \u0000 \u0000Key words: \u0000Statin; Cardioembolic stroke; Collateral circulation; Large vessel occlusion; Cerebral infarction","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"77 1","pages":"1142-1145"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90513251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.005
Zhao-shuo Li, Teng-fei Zhou, Qiang Li, Min Guan, Huan-Ho Liu, Liang-fu Zhu, Zi-liang Wang
{"title":"Efficacy and safety of a direct aspiration first-pass thrombectomy technique in treating atherosclerotic acute intracranial large vessel occlusion","authors":"Zhao-shuo Li, Teng-fei Zhou, Qiang Li, Min Guan, Huan-Ho Liu, Liang-fu Zhu, Zi-liang Wang","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.005","url":null,"abstract":"Objective \u0000To investigate the efficacy and safety of a direct aspiration first-pass thrombectomy (ADAPT) technique in treating acute atherosclerotic intracranial large vessel occlusion. \u0000 \u0000 \u0000Methods \u0000Seventy-two patients with acute atherosclerotic intracranial large vessel occlusion underwent endovascular treatment in our hospital from March 2018 to March 2019 were chosen in our study; ADAPT technique was used in 24 patients, and Solitaire stent combined with penumbra suction catheter extraction (Solumbra) technique was used in 48 patients. Remedial measures were adopted after the failure of recanalization. Modified intraoperative cerebral infarction thrombolysis grading was used for vascular recanalization evaluation. The prognoses of the patients were determined according to modified Rankin scale (mRS) scores 3 months after operation, and the efficacy and safety of the patients in the two groups were compared. \u0000 \u0000 \u0000Results \u0000As compared with patients in the Solumbra group, patients in the ADAPT group had statistically shorter time from femoral artery puncture to reflow (P 0.05). The final recanalization rates of patients in Solumbra group and ADAPT group were 83.33% and 75.00%, without statistically significant difference (P>0.05). There was no significant difference in proportion of patients with good prognosis, incidence of perioperative symptomatic intracranial hemorrhage and mortality between the two groups (P>0.05). \u0000 \u0000 \u0000Conclusion \u0000For patients with acute atherosclerotic intracranial large vessel occlusion, endovascular treatment with ADAPT technique is comparable with Solumbra technique. \u0000 \u0000 \u0000Key words: \u0000Atherosclerosis; Acute intracranial large vessel occlusion; A direct aspiration first-pass thrombectomy technique; Solitaire stent combined with penumbra suction catheter extraction technique","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"1 1","pages":"1103-1108"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83625131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.006
Yi Zhang, Min Zhang, W. Yun, Yin Cao, Yuan Chen, Zhixiang Zhang, Yu-qian Tao, Jingjing Wang, Xianju Zhou
{"title":"Influence of estimated glomerular filtration rate in motor function rehabilitation and short-term prognoses in patients with acute middle cerebral artery infarction","authors":"Yi Zhang, Min Zhang, W. Yun, Yin Cao, Yuan Chen, Zhixiang Zhang, Yu-qian Tao, Jingjing Wang, Xianju Zhou","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.006","url":null,"abstract":"Objective \u0000To investigate the influence of estimated glomerular filtration rate (eGFR) in rehabilitation of motor function and short-term prognoses in patients with acute middle cerebral artery (MCA) infarction. \u0000 \u0000 \u0000Methods \u0000Seventy-four patients with acute MCA infarction, admitted to Department of Neurology from March 2016 to September 2018, and then, accepted rehabilitation training for 4 weeks in Department of Rehabilitation medicine, were recruited. Modification of Diet in Renal Disease was used to evaluate the eGFR instead of renal function; according to the results, these patients were divided into normal renal function group and mild-moderate renal dysfunction group. National Institute of Health Stroke Scale (NIHSS) was used to assess the neurologic function. Fazekas scale was used to assess degrees of leukoaraiosis. Fugl-Meyer Motor Function Assessment (FMA) was used to assess motor functions before rehabilitation treatment and 90 d after onset. Modified Barthel Index (MBI) was used to assess activity of daily living 90 d after onset. According to MBI scores, the patients were divided into good prognosis group (MBI scores>60) and poor prognosis group (MBI scores≤60); multivariate Logistic regression analysis was used to confirm the risk factors affecting prognoses 90 d after onset. \u0000 \u0000 \u0000Results \u0000Among 74 enrolled patients, 40 were classified as normal renal function group and 34 as mild-moderate renal dysfunction group; patients in the mild-moderate renal dysfunction group had significantly higher level of blood urea nitrogen, proportion of silent lacunar cerebral infarction and Fazekas scale scores, and had statistically lower FMA scores and MBI 90 d after onset than normal renal function group (P<0.05). Among the 74 patients, good prognosis was found in 32 patients and poor prognosis in 42 patients; multivariate Logistic regression analysis found that age, eGFR (OR=0.944, P= 0.011, 95%CI: 0.903-0.987), baseline NIHSS scores, and Fazekas scale scores were risk factors affecting prognoses 90 d after onset. \u0000 \u0000 \u0000Conclusion \u0000In acute MCA infarction patients, eGFR can influence the rehabilitation of motor function and short-term prognoses. \u0000 \u0000 \u0000Key words: \u0000Cerebral infarction; Middle cerebral artery; Estimated glomerular filtration rate; Motor function; Rehabilitation; Short-term prognosis","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"170 1","pages":"1109-1115"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74872848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华神经医学杂志Pub Date : 2019-11-15DOI: 10.3760/CMA.J.ISSN.1671-8925.2019.11.004
Hua Yang, Chun-ou Tian, Qianghua He
{"title":"Efficacy and safety of carotid endarterectomy in restenosis after carotid stenosis stenting","authors":"Hua Yang, Chun-ou Tian, Qianghua He","doi":"10.3760/CMA.J.ISSN.1671-8925.2019.11.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-8925.2019.11.004","url":null,"abstract":"Objective \u0000To evaluate the efficacy and safety of carotid endarterectomy (CEA) in restenosis after carotid stenosis stenting. \u0000 \u0000 \u0000Methods \u0000In a prospective study, 29 patients with restenosis after carotid artery stenosis stenting, admitted to our hospital from January 2017 to December 2017, were selected as study group; and 29 patients with moderate or severe carotid artery stenosis matched with age, gender and course of disease and admitted to our hospital at the same period were selected as control group. All of them were treated with CEA, and patients in the study group also had their stents removed. The patients in the two groups were compared in terms of surgical indicators, efficacy, perioperative complications and incidence of adverse events during follow-up. \u0000 \u0000 \u0000Results \u0000The success rate of surgery was 100% in both groups; the intraoperative flow rate was 10.34% in the control group and 17.24% in the study group without statistically significant difference (P>0.05). There were no significant differences in carotid artery occlusion times and operation times between the two groups (P>0.05). The lengths of skin incision and carotid artery incision in the study group were significantly longer than those in the control group (P 0.05). The incidence of perioperative complications was 10.34% in the study group, and the incidence of adverse events was 10.34% in the follow-up period, and 3.45% and 6.90% in the control group, respectively, without statistically significant differences (P>0.05). \u0000 \u0000 \u0000Conclusions \u0000CEA is effective in the treatment of restenosis after carotid stenosis stenting. Because of stent dissection, the skin and carotid artery incision lengths are relatively long, but it does not increase the surgery risks and complications. \u0000 \u0000 \u0000Key words: \u0000Carotid endarterectomy; Stent molding; Carotid artery stenosis; Curative effect; Safety","PeriodicalId":10104,"journal":{"name":"中华神经医学杂志","volume":"59 1","pages":"1098-1102"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75418143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}