Recent advance in treatment of Meige syndrome

Abstract

Meige syndrome is a rare segmental craniocervical dystonia, mainly characterized by blepharospasm and involuntary contraction of jaw and neck muscles, which will seriously decrease the patient's quality of life. The etiology and pathogenesis of the disease remain unclear, despite of some progress having been made in the relevant studies. Current treatments include drug therapy, botulinum toxin A injection and surgical treatment. In this article, the pathogenesis, clinical manifestations and treatment of Meige syndrome will be briefly reviewed. Key words: Meige syndrome; Dystonia; Botulinum toxin; Deep brain stimulation