Chinese Chemical Letters最新文献_第4页

Targeting novel sites represents an effective strategy for combating drug resistance 靶向新位点是对抗耐药性的有效策略

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-30 DOI: 10.1016/j.cclet.2024.110378

Shaoqing Du , Xinyong Liu , Xueping Hu , Peng Zhan

引用次数: 0

Topologically close-packed intermetallic alloy electrocatalysts for CO2 reduction towards high value-added multi-carbon chemicals 拓扑紧密堆积金属间合金电催化剂，用于还原二氧化碳，生产高附加值多碳化学品

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-30 DOI: 10.1016/j.cclet.2024.110384

Qiyan Wu, Qing Li

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Mini review: Strategies for enhancing stability of high-voltage cathode materials in aqueous zinc-ion batteries 小评论：提高锌离子水电池中高压阴极材料稳定性的策略

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-25 DOI: 10.1016/j.cclet.2024.110368

Lingjiang Kou , Yong Wang , Jiajia Song , Taotao Ai , Wenhu Li , Mohammad Yeganeh Ghotbi , Panya Wattanapaphawong , Koji Kajiyoshi

{"title":"Mini review: Strategies for enhancing stability of high-voltage cathode materials in aqueous zinc-ion batteries","authors":"Lingjiang Kou , Yong Wang , Jiajia Song , Taotao Ai , Wenhu Li , Mohammad Yeganeh Ghotbi , Panya Wattanapaphawong , Koji Kajiyoshi","doi":"10.1016/j.cclet.2024.110368","DOIUrl":"10.1016/j.cclet.2024.110368","url":null,"abstract":"<div><div>As battery technology evolves and demand for efficient energy storage solutions, aqueous zinc ion batteries (AZIBs) have garnered significant attention due to their safety and environmental benefits. However, the stability of cathode materials under high-voltage conditions remains a critical challenge in improving its energy density. This review systematically explores the failure mechanisms of high-voltage cathode materials in AZIBs, including hydrogen evolution reaction, phase transformation and dissolution phenomena. To address these challenges, we propose a range of advanced strategies aimed at improving the stability of cathode materials. These strategies include surface coating and doping techniques designed to fortify the surface properties and structure integrity of the cathode materials under high-voltage conditions. Additionally, we emphasize the importance of designing antioxidant electrolytes, with a focus on understanding and optimizing electrolyte decomposition mechanisms. The review also highlights the significance of modifying conductive agents and employing innovative separators to further enhance the stability of AZIBs. By integrating these cutting-edge approaches, this review anticipates substantial advancements in the stability of high-voltage cathode materials, paving the way for the broader application and development of AZIBs in energy storage.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 1","pages":"Article 110368"},"PeriodicalIF":9.4,"publicationDate":"2024-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A TOC- and deposition-free electrochromic window driven by redox flow battery 氧化还原液流电池驱动的无 TOC 和沉积物电致变色窗

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-23 DOI: 10.1016/j.cclet.2024.110355

Jinlong Li , Ruixin Li , Jiahui Liu , Ji-Quan Liu , Jia Xu , Xianglin Zhou , Yefan Zhang , Kairui Wang , Lin Lei , Gang Xie , Fengmei Wang , Ying Yang , Liping Cao

{"title":"A TOC- and deposition-free electrochromic window driven by redox flow battery","authors":"Jinlong Li , Ruixin Li , Jiahui Liu , Ji-Quan Liu , Jia Xu , Xianglin Zhou , Yefan Zhang , Kairui Wang , Lin Lei , Gang Xie , Fengmei Wang , Ying Yang , Liping Cao","doi":"10.1016/j.cclet.2024.110355","DOIUrl":"10.1016/j.cclet.2024.110355","url":null,"abstract":"<div><p>Under “green architecture” principles, electrochromic smart windows are employed to adjust optical transmittance and indoor temperature, yet their high costs limit the wide application. Here, an electrochromic window is driven by a redox flow battery (RFB), where TOC and deposition layers are no longer needed. The transmittance of the electrochromic window is modulated by the state of oxidation (SOC) of aqueous posolyte Fe(phen)<sub>3</sub>Cl<sub>2</sub>, which is coupled with BTMAP-Vi negolyte in RFB. Under optimized conditions, average CE, VE, and EE reach 93.25 %, 92.61 %, and 86.35 % for RFB with a capacity fading rate of 1.57 % per cycle. 88.66 % optical modulation and 9.36 cm<sup>2</sup>/C coloration efficiency are achieved in the electrochromic process, and 72.34 % optical modulation is maintained after 12000 s. Essentially, the indoor temperature declines 3 °C for posolyte with 100 % SOC when compared with the control experiment using circulating water for a model house. This means minimum electricity of 0.0185 kWh is saved when using an air conditioner to cool a 100 m<sup>3</sup> house, which corresponds to declined CO<sub>2</sub> emission (COE) of 0.0185 kg. This work provides a novel and cost-efficient strategy for modulating indoor comfort <em>via</em> electrochromic windows driven by RFB.</p></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"35 12","pages":"Article 110355"},"PeriodicalIF":9.4,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142172858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surface controllable wettability using amphiphilic rotaxane molecular shuttles 利用两亲性轮烷分子穿梭器实现表面可控润湿性

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-23 DOI: 10.1016/j.cclet.2024.110353

Dongpu Wu, Zheng Yang, Yuchen Xia, Lulu Wu, Yingxia Zhou, Caoyuan Niu, Puhui Xie, Xin Zheng, Zhanqi Cao

引用次数: 0

Plasma metabolomics combined with mass spectrometry imaging reveals crosstalk between tumor and plasma in gastric cancer genesis and metastasis 血浆代谢组学结合质谱成像揭示了胃癌发生和转移过程中肿瘤与血浆之间的相互影响

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-20 DOI: 10.1016/j.cclet.2024.110351

Yanhua Chen , Xian Ding , Jun Zhou , Zhaoying Wang , Yunhai Bo , Ying Hu , Qingce Zang , Jing Xu , Ruiping Zhang , Jiuming He , Fen Yang , Zeper Abliz

{"title":"Plasma metabolomics combined with mass spectrometry imaging reveals crosstalk between tumor and plasma in gastric cancer genesis and metastasis","authors":"Yanhua Chen , Xian Ding , Jun Zhou , Zhaoying Wang , Yunhai Bo , Ying Hu , Qingce Zang , Jing Xu , Ruiping Zhang , Jiuming He , Fen Yang , Zeper Abliz","doi":"10.1016/j.cclet.2024.110351","DOIUrl":"10.1016/j.cclet.2024.110351","url":null,"abstract":"<div><div>Gastric Carcinoma (GC) is a highly fatal malignant tumor with a poor prognosis. Its elevated mortality rates are primarily due to its proclivity for late-stage metastasis. Exploring the metabolic interactions between tumor microenvironment and the systemic bloodstream could help to clearly understand the mechanisms and identify precise biomarkers of tumor growth, proliferation, and metastasis. In this study, an integrative approach that combines plasma metabolomics with mass spectrometry imaging of tumor tissue was developed to investigate the global metabolic landscape of GC tumorigenesis and metastasis. The results showed that the oxidized glutathione to glutathione ratio (GSSH/GSH) became increased in non-distal metastatic GC (M0), which means an accumulation of oxidative stress in tumor tissues. Furthermore, it was found that the peroxidation of polyunsaturated fatty acids, such as 9,10-EpOMe, 9-HOTrE, <em>etc</em>., were accelerated in both plasma and tumor tissues of distal metastatic GC (M1). These changes were further confirmed the potential effect of CYP2E1 and GGT1 in metastatic potential of GC by mass spectrometry imaging (MSI) and immunohistochemistry (IHC). Collectively, our findings reveal the integrated multidimensional metabolomics approach is a clinical useful method to unravel the blood-tumor metabolic crosstalk, illuminate reprogrammed metabolic networks, and provide reliable circulating biomarkers.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 1","pages":"Article 110351"},"PeriodicalIF":9.4,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IFC - Editorial Board/ Publication info 国际金融公司 - 编辑委员会/出版信息

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-14 DOI: 10.1016/S1001-8417(24)00782-4

引用次数: 0

H2S and NIR light-driven nanomotors induce disulfidptosis for targeted anticancer therapy by enhancing disruption of tumor metabolic symbiosis H2S和近红外光驱动的纳米马达通过加强对肿瘤代谢共生的破坏，诱导二硫化氢，实现抗癌靶向治疗

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-02 DOI: 10.1016/j.cclet.2024.110314

Shangqian Zhang, Jiaxuan Li, Xuan Hu, Zelong Chen, Junliang Dong, Chenhao Hu, Shuang Chao, Yinghua Lv, Yuxin Pei, Zhichao Pei

{"title":"H2S and NIR light-driven nanomotors induce disulfidptosis for targeted anticancer therapy by enhancing disruption of tumor metabolic symbiosis","authors":"Shangqian Zhang, Jiaxuan Li, Xuan Hu, Zelong Chen, Junliang Dong, Chenhao Hu, Shuang Chao, Yinghua Lv, Yuxin Pei, Zhichao Pei","doi":"10.1016/j.cclet.2024.110314","DOIUrl":"10.1016/j.cclet.2024.110314","url":null,"abstract":"<div><div>Disulfidptosis, a novel mechanism of programmed cell death through the disruption of tumor metabolic symbiosis (TMS), has showed tremendous potential in cancer therapy. However, the efficacy of disulfidptosis is limited by poor permeability of drugs in solid tumors. Herein, hydrogen sulfide (H<sub>2</sub>S) and near-infrared (NIR) light-driven nanomotors (denoted as HGPP) have been constructed to efficiently penetrate tumors and induce disulfidptosis. HGPP demonstrate glutathione (GSH)-responsive release of H<sub>2</sub>S, which combined with NIR light-induced photothermal effect drive HGPP movement to facilitate deep tumor penetration. The released H<sub>2</sub>S induces tumor acidosis and disrupts TMS, where disulfide accumulation following cell starvation leads to disulfidptosis. In addition, HGPP induce hepatoma specific cellular uptake and catalyze the conversion of glucose and oxygen to produce hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), leading to glucose starvation. Overall, this study has developed a multifunctional Janus nanomotor that provides a novel strategy for disulfidptosis-based solid tumor therapy.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 1","pages":"Article 110314"},"PeriodicalIF":9.4,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polydopamine-modified biochar supported polylactic acid and zero-valent iron affects the functional microbial community structure for 1,1,1-trichloroethane removal in simulated groundwater 聚多巴胺改性生物炭（支持聚乳酸和零价铁）影响模拟地下水中去除 1,1,1- 三氯乙烷的功能微生物群落结构

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-08-02 DOI: 10.1016/j.cclet.2024.110313

Haitao Yin , Liang Meng , Li Li , Jiamu Xiao , Longrui Liang , Nannan Huang , Yansong Shi , Angang Zhao , Jingwen Hou

{"title":"Polydopamine-modified biochar supported polylactic acid and zero-valent iron affects the functional microbial community structure for 1,1,1-trichloroethane removal in simulated groundwater","authors":"Haitao Yin , Liang Meng , Li Li , Jiamu Xiao , Longrui Liang , Nannan Huang , Yansong Shi , Angang Zhao , Jingwen Hou","doi":"10.1016/j.cclet.2024.110313","DOIUrl":"10.1016/j.cclet.2024.110313","url":null,"abstract":"<div><div><em>In-situ</em> enhanced bioreduction by functional materials is a cost-effective technology to remove chlorinated hydrocarbons in groundwater. Herein, a novel polydopamine (PDA)-modified biochar (BC)-based composite containing nanoscale zero-valent iron (nZVI) and poly-<span>l</span>-lactic acid (PLLA) (PB-PDA-Fe) was synthesized to enhance the removal of 1,1,1-trichloroethane (1,1,1-TCA) in simulated groundwater with actual site sediments. Its impact on functional microbial community structure in system was also investigated. The typical characterizations revealed uniform dispersion of PLA and nZVI particles on the BC surface, being smoother after PDA coating. The composite exhibited a significantly higher performance on 1,1,1-TCA removal (82.38%, initial concentration 100 mg/L) than Fe-PDA and PB-PDA treatments. The diversity and richness of the microbial community in the composite treatment consistently decreased during incubation due to a synergistic effect between PLLA-BC and nZVI. <em>Desulfitobaterium, Pedobacter, Sphaerochaeta, Shewanella</em>, and <em>Clostridium</em> were identified as enriched genera by the composite through DNA-stable isotope probing (DNA-SIP), playing a crucial role in the bioreductive dechlorination process. All the above results demonstrate that this novel composite selectively enhances the activity of microorganisms with extracellular respiration functions to efficiently dechlorinate 1,1,1-TCA. These findings could contribute to understanding the responsive microbial community by carbon-iron composites and expedite the application of <em>in-situ</em> enhanced bioreduction for effective remediation of chlorinated hydrocarbon-contaminated groundwater.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 1","pages":"Article 110313"},"PeriodicalIF":9.4,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in virus-host interaction research based on microfluidic platforms 基于微流控平台的病毒-宿主相互作用研究进展

IF 9.4 1区化学

Chinese Chemical Letters Pub Date : 2024-07-31 DOI: 10.1016/j.cclet.2024.110302

Cheng Wang , Ji Wang , Dong Liu , Zhi-Ling Zhang

{"title":"Advances in virus-host interaction research based on microfluidic platforms","authors":"Cheng Wang , Ji Wang , Dong Liu , Zhi-Ling Zhang","doi":"10.1016/j.cclet.2024.110302","DOIUrl":"10.1016/j.cclet.2024.110302","url":null,"abstract":"<div><p>Viral epidemics pose a serious threat to global public health, making it essential to explore virus-host interactions for uncovering the pathogenesis of viral diseases and developing effective antiviral strategies. Traditional <em>in vitro</em> cell infection models struggle to replicate physiological microenvironment, while animal infection models may encounter obstacles such as species gap, high-cost, and ethical issues. Additionally, potential heterogeneous infection outcomes are usually inaccessible by population-based experiments. Microfluidics, as an emerging interdisciplinary platform, has proven to be a powerful tool for inquiring virus-host interactions. In this review, conventional virological methods were introduced first and remarkable advantages of microfluidics in viral cell biology were highlighted. Next, the in-depth applications of microfluidics in analyzing heterogeneity of virus-host interplays, dynamic monitoring of events related to viral life cycle, and modeling of viral infectious diseases were fully elaborated from the perspective of single-cell chip, multi-cell culture chip and organ-on-a-chip (organ chip). Finally, the opportunities and challenges in developing robust microfluidic methods for virology were discussed. Overall, this review aims to provide an overview of microfluidic-based research on virus-host interaction and promote multidisciplinary collaborations for better understanding and responding to viral threats.</p></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"35 12","pages":"Article 110302"},"PeriodicalIF":9.4,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0