Chinese Chemical Letters最新文献_第4页

Recent development in fluorescent probes for monitoring organophosphorus pollutants 荧光探针监测有机磷污染物的研究进展

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-09-26 DOI: 10.1016/j.cclet.2025.111902

Kun Song , Lijia Zhang , Yunhui Meng , Jiantong Ding , Xiaobai Li , Yongpeng Liu , Hongwei Ma

引用次数: 0

Synergistic homogeneous photochemical and halogen-bond catalysis toward antitumor sulfonylated fused (hetero)arenes 协同均相光化学和卤素键催化抗肿瘤磺化融合（杂）芳烃

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2026-01-06 DOI: 10.1016/j.cclet.2026.112373

Jia-Sheng Wang , Lin-Heng He , Yan-Ting Liu , Yu-Ting Wu , Hai-Tao Zhu , Sheng-Hua Wang , Yu-Yu Tan , Wei-Min He , Yong-Hong Zhang

引用次数: 0

Construction of donor-acceptor supramolecular organic framework with enhanced superoxide anion radical generation for photocatalytic synthesis of benzimidazole 光催化合成苯并咪唑用增强超氧阴离子自由基生成的供受体超分子有机框架的构建

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-07 DOI: 10.1016/j.cclet.2025.111426

Xianya Yao , Ning Han , Hui Liu , Lingbao Xing

{"title":"Construction of donor-acceptor supramolecular organic framework with enhanced superoxide anion radical generation for photocatalytic synthesis of benzimidazole","authors":"Xianya Yao , Ning Han , Hui Liu , Lingbao Xing","doi":"10.1016/j.cclet.2025.111426","DOIUrl":"10.1016/j.cclet.2025.111426","url":null,"abstract":"<div><div>The fabrication of three-component supramolecular organic frameworks (SOFs) is a considerable difficulty owing to the intricate noncovalent interactions and the constraints of current synthesis techniques. In this study, we designed and synthesized two photosensitive modules: a naphthalene-modified triphenylamine derivative (NA-TPA) as the donor unit, and a trimethylated viologen-modified triphenylamine (MV-TPA) as the acceptor unit. These modules can self-assemble into a novel two-dimensional SOF <em>via</em> encapsulation-enhanced donor-acceptor interactions with cucurbit[8]uril (CB[8]) in the aqueous solution. The resulting donor-acceptor SOF forms stable two-dimensional nanosheet structures in water. Compared to the individual monomers NA-TPA and MV-TPA, the SOF enhances electron transfer and significantly improves the generation of superoxide anion radicals (O<sub>2</sub><sup>•−</sup>), which in turn effectively promotes the photocatalytic cyclization reaction between <em>o</em>-phenylenediamine and benzaldehyde in water, achieving a yield of up to 94 %. This work offers valuable insights into the design and construction of three-component SOFs based on encapsulation-enhanced donor-acceptor interactions for photocatalytic applications.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111426"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monofluoroiodane(III) reagent mediated Wagner−Meerwein rearrangement fluorination: Construction of quaternary C(sp3)−F bond 单氟碘烷（III）试剂介导的Wagner - Meerwein重排氟化：四元C(sp3) - F键的构建

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-04 DOI: 10.1016/j.cclet.2025.111407

Jing Ren , Feng-Huan Du , Xiaowei Chen , Chi Zhang

{"title":"Monofluoroiodane(III) reagent mediated Wagner−Meerwein rearrangement fluorination: Construction of quaternary C(sp3)−F bond","authors":"Jing Ren , Feng-Huan Du , Xiaowei Chen , Chi Zhang","doi":"10.1016/j.cclet.2025.111407","DOIUrl":"10.1016/j.cclet.2025.111407","url":null,"abstract":"<div><div>Fluoroorganic chemistry is one of the most hectic areas of current chemical research, exerting a profound effect on the most vital industries such as medicine, pesticide, and material science. Synthesis of fluorine-containing organic molecules, particularly those that bear C(sp<sup>3</sup>)−F bonds, remains a great challenge in modern chemical synthesis. Herein, we disclose a new strategy for the construction of a carbon−fluorine quaternary center, which was accomplished with the silver(I)-catalyzed intramolecular Wagner−Meerwein rearrangement fluorination of allylic gem-disubstituted alkene derivatives by using a hypervalent monofluoroiodine(III) reagent <strong>1</strong> (<strong>AFBI</strong>). Interestingly, the tunable five/six-membered heterocycle selectivity is achieved by the intramolecular Wagner−Meerwein rearrangement fluorination <em>via</em> a judicious choice of the group R<sup>1</sup> attached to the C−C double bond. This versatile strategy features simple starting materials, mild reaction conditions, good functional-group compatibility, high bond-forming efficiency (<em>e.g</em>., one C−F and one C−O bond), and excellent chemoselectivity. The proposed reaction mechanisms and the roles of the catalyst AgBF<sub>4</sub> were understood by control experiments and density functional theory calculations.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111407"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A concise asymmetric synthesis of (–)-oseltamivir phosphate via a biphasic Pd-catalyzed Heck-type cyclization 通过双相pd催化heck型环化合成(-)-磷酸奥司他韦的简明不对称合成

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-07-11 DOI: 10.1016/j.cclet.2025.111555

Qi Wang , Bichu Cheng , Minjie Liu , Fen-Er Chen

引用次数: 0

Enantioselective intramolecular C–H alkylation of pyridine derivatives with alkene by rare-earth catalysts: Facile synthesis of chiral tetrahydro-1,5-naphthyridines 稀土催化剂对映选择性吡啶衍生物与烯烃的分子内C-H烷基化反应：手性四氢-1,5-萘啶的简易合成

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-06-11 DOI: 10.1016/j.cclet.2025.111442

Jing Zhang , Lichao Ning , Yong Qiu , Minghui Ji , Shiyu Wang , Yuji Wang , Fei Wang , Xiaoming Feng , Shunxi Dong

{"title":"Enantioselective intramolecular C–H alkylation of pyridine derivatives with alkene by rare-earth catalysts: Facile synthesis of chiral tetrahydro-1,5-naphthyridines","authors":"Jing Zhang , Lichao Ning , Yong Qiu , Minghui Ji , Shiyu Wang , Yuji Wang , Fei Wang , Xiaoming Feng , Shunxi Dong","doi":"10.1016/j.cclet.2025.111442","DOIUrl":"10.1016/j.cclet.2025.111442","url":null,"abstract":"<div><div>Chiral 1,2,3,4-tetrahydro-1,5-naphthyridines are frequently encountered in many bioactive compounds. However, the methods for their asymmetric synthesis are quite limited. Herein, we developed a straightforward and efficient route to enantioenriched tetrahydro-1,5-naphthyridines from pyridine derivatives tethered with alkene moieties (34 examples, up to 99 % yield, 93 % <em>ee</em>). The reaction proceeded <em>via</em> Csp<sup>2</sup>‒H activation pathway initiated by site-selective deprotonation with the assistance of La[N(SiMe<sub>3</sub>)<sub>2</sub>]<sub>3</sub>/<strong>PyBox</strong>, followed by alkene insertion into the resulting La-aryl bond. The potential utility of the current method in organic synthesis was highlighted by scale-up synthesis of chiral product and its further transformations. Moreover, some of the products show a pronounced inhibitory effect on A549 cell activity. In addition, experimental studies and DFT calculations were carried out to elucidate the origin of enantiocontrol.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111442"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metallocene-based molecule junctions: Electron transport across Au||Au and Au||graphene electrodes 茂金属基分子结：Au||Au和Au b| |石墨烯电极上的电子传输

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-09-09 DOI: 10.1016/j.cclet.2025.111811

Chang Liu , Jianbo Li , Yijia Wang , Chenguang Liu , Sylvain Pitie , Mahamadou Seydou , Chun Zhao , Paul J. Low , Yannick J. Dappe , Li Yang

{"title":"Metallocene-based molecule junctions: Electron transport across Au||Au and Au||graphene electrodes","authors":"Chang Liu , Jianbo Li , Yijia Wang , Chenguang Liu , Sylvain Pitie , Mahamadou Seydou , Chun Zhao , Paul J. Low , Yannick J. Dappe , Li Yang","doi":"10.1016/j.cclet.2025.111811","DOIUrl":"10.1016/j.cclet.2025.111811","url":null,"abstract":"<div><div>Metallocenes are a wide family of organometallic compounds, in which two cyclopentadienyl ligands ‘sandwich’ a metal ion, M(<em>η</em><sup>5</sup>-C<sub>5</sub>R<sub>5</sub>)<sub>2</sub>, and have considerable potential for use as components in molecular electronics applications. Here we have studied the electronic transport properties of the matallocenes MCp<sub>2</sub> (M = V, Cr, Mn, Fe, Co, Ni, Ru; Cp = <em>η</em><sup>5</sup>-C<sub>5</sub>H<sub>5</sub>) and MCp*<sub>2</sub> (M =  Mn, Fe, Co; Cp* = <em>η</em><sup>5</sup>-C<sub>5</sub>Me<sub>5</sub>). Molecular junctions have been fabricated using either two gold, or one gold and one graphene electrode(s), giving rise to single-molecule conductance values of the order of -4 to -3 log(<em>G</em>/<em>G</em><sub>0</sub>)) depending on both the nature of the metallocene and the electrode materials. Calculations on model junctions at the density functional theory level of theory reveal significant charge transfer from the metallocene to the junction electrodes and changes in the nature of the primary charge transport pathways in response to the nature of the metal, supporting ligands, molecular oxidation state and electrode composition.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111811"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances on asymmetric reduction via dynamic kinetic resolution 动态动力学分辨非对称还原研究进展

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-09-30 DOI: 10.1016/j.cclet.2025.111929

Ao Zhou , Mostafa M.K. Amer , Qin Yin

{"title":"Recent advances on asymmetric reduction via dynamic kinetic resolution","authors":"Ao Zhou , Mostafa M.K. Amer , Qin Yin","doi":"10.1016/j.cclet.2025.111929","DOIUrl":"10.1016/j.cclet.2025.111929","url":null,"abstract":"<div><div>Asymmetric reduction of unsaturated compounds <em>via</em> dynamic kinetic resolution (DKR) has significantly enhanced the efficiency and selectivity of synthesizing enantiomerically pure compounds from racemic substrates. This approach combines the simultaneous racemization of substrates with enantioselective reduction, enabling quantitative yields and high enantiomeric excess. In the past several years, remarkable advances in this field have been achieved, ranging from the development of innovative catalytic systems, novel synthetic strategies, expansion of substrate scope, deeper mechanistic understanding, and their applications. These advancements offer alternative and efficient methods in the asymmetric synthesis of chiral molecules bearing multiple consecutive stereogenic centers, particularly beneficial for the synthesis of natural products or chiral intermediates in pharmaceuticals and fine chemicals. In this review, we summarize the recent advances during the last several years according to the substrate types in this powerful and productive field, with an emphasis on the development of new catalytic systems and the insight into the DKR process.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 5","pages":"Article 111929"},"PeriodicalIF":8.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146186613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inverse-electron-demand Diels–Alder approach to densely substituted bicyclo[3.2.2]nonanes: Discovery of an autophagy regulator 密集取代双环壬烷的逆电按需Diels-Alder方法：自噬调节因子的发现

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-05-01 Epub Date: 2025-05-27 DOI: 10.1016/j.cclet.2025.111381

Jiulong Li , Pengxin Ren , Lin Wang , Yuting Zhang , Peng Yang , Weiwei He , Ang Li

引用次数: 0

Covalent organic framework photocatalysts: Design and photocatalytic U(VI) separation 共价有机骨架光催化剂：设计与光催化U（VI）分离

IF 9.5 1区化学

Chinese Chemical Letters Pub Date : 2026-04-08 DOI: 10.1016/j.cclet.2026.112742

Yougan Wang, Sanmei Liu, Fangfang Li, Zhijian Li, Leilei Sun, Congbin Fan, Chunhui Deng

{"title":"Covalent organic framework photocatalysts: Design and photocatalytic U(VI) separation","authors":"Yougan Wang, Sanmei Liu, Fangfang Li, Zhijian Li, Leilei Sun, Congbin Fan, Chunhui Deng","doi":"10.1016/j.cclet.2026.112742","DOIUrl":"10.1016/j.cclet.2026.112742","url":null,"abstract":"<div><div>The highly selective and effective separation of radioactive uranium from wastewater containing uranium and seawater through photocatalytic technique holds great significance for alleviating the energy crisis and protecting the environment, yet it also presents great challenges. Covalent organic frameworks (COFs) are considered desirable photocatalytic candidates for separating hexavalent uranium (U(VI)) on account of their tunable and programmable structure. Herein, the crucial advances in COF-based photocatalysts for U(VI) photocatalytic reduction from radioactive wastewater and seawater are presented, emphasizing particularly the relationship between structure-property-activity. A detailed discussion is conducted on the design of linkage of COF for important factors affecting photocatalysis. Subsequently, the performance enhancement strategies (such as morphology control, skeleton functionalization, hybrid materials, metalized, elemental doping and piezo-photocatalysis) are systematically highlighted. The experimental parameters of COF photocatalysts for practical application in radioactive wastewater or seawater are discussed, and the underlying mechanisms of U(VI) photocatalytic reduction by COF materials carefully analyzed. Finally, the challenges and prospects of COFs-based photocatalysts on separation U(VI) are envisaged, and a variety of strategies for improving the performance are elaborated. This review establishes the structure-activity relationship between COF linkages, band structure, and uranium reduction efficiency, which aims to and affords guidance for the design and synthesis of diverse COF-based photocatalyst with excellent photocatalytic performance to achieve the high-efficiency photoreduction U(VI) from radioactive wastewater and seawater.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 12","pages":"Article 112742"},"PeriodicalIF":9.5,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148870726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0